Simultaneous effect of medicinal plants as natural photosensitizers and low-level laser on photodynamic inactivation
This study presents a promising avenue for further exploration of PDI and the use of laser technology in medical science. (Source: Lasers in Medical Science)
Source: Lasers in Medical Science - March 27, 2024 Category: Laser Surgery Source Type: research
The effect of combined red, blue, and near-infrared light-emitting diode (LED) photobiomodulation therapy on speed of wound healing after superficial ablative fractional resurfacing
In conclusion, PBM therapy has the potential to improve wound healing. In this study, a three wavelength PBM device resulted in some subjects achieving faster healing after AFL but the results were not statistically significant. (Source: Lasers in Medical Science)
Source: Lasers in Medical Science - March 27, 2024 Category: Laser Surgery Source Type: research
Blue Laser for Polymerization of Bulk Fill Composites: Influence on dentin bond strength and temperature rise during curing and co-curing method
AbstractBlue diode lasers are alternative curing devices for dental composites. The aim of this study was to investigate the influence of blue diode laser polymerization on shear bond strength of bulk fill composites to human dentin and temperature rise during two types of polymerization. Composite cylinders of SDR Plus(SDR) and Ever X Flow(EX) were bonded to dentin slabs using Adhese Universal and curing devices blue diode laser (449 nm, 1.6 W) and Power Cure LED. For each material and curing device there were two polymerization approaches: 1)conventional: separate curing of adhesive; 2)co-curing: simultaneous adhesive ...
Source: Lasers in Medical Science - March 23, 2024 Category: Laser Surgery Source Type: research
Recent advances in the treatment of acne using radiofrequency techniques
AbstractAcne is a long-lasting inflammatory skin condition that impacts the sebaceous units of the hair follicles, affecting around 85 –90% of the population. Due to the potential for permanent facial scarring and negative social consequences, as well as the limitations of conventional medications like drug resistance and difficulties following treatment plans, it’s crucial to investigate non-pharmacological options for treatin g acne, among which radiofrequency(RF) shows distinct superiority. To assess the impact of RF in the management of acne vulgaris, we conducted a thorough examination of scientific literature (in...
Source: Lasers in Medical Science - March 19, 2024 Category: Laser Surgery Source Type: research
Synergistic effect of mesoporous silica nanocarrier-assisted photodynamic therapy and anticancer agent activity on lung cancer cells
This study aims to explore the combined effects of photodynamic and anticancer treatments using a multifunctional nanocarrier system co-administering the photosensitizer IR780 and the anticancer agent curcumin (Cur) on lung cancer cells. Nanocarriers were prepared by encapsulation IR780 and Cur inside polyethylene glycol-capped mesoporous silica nanoparticles (Cur&IR780@MSN). Various concentrations of nanocarriers were evaluated on A549 cells following 5 min NIR laser light (continuous wave, 785 nm, 500 mW/cm2) irradiation. The internalization of nanocarriers was observed through the fluorescence of Cur. Changes in ...
Source: Lasers in Medical Science - March 16, 2024 Category: Laser Surgery Source Type: research
Effects of photobiomodulation on pain, lactate and muscle performance (ROM, torque, and EMG parameters) of paretic upper limb in patients with post-stroke spastic hemiparesis —a randomized controlled clinical trial
In conclusion, Photobiomodulation (PBM) demonstrated significant improvements in muscle performance, reducing fatigue and pain levels, and enhancing range of motion in post-st roke patients with spastic hemiparesis. These findings support the potential integration of PBM into rehabilitation protocols, but further research and clinical trials are needed to validate and expand upon these promising outcomes. (Source: Lasers in Medical Science)
Source: Lasers in Medical Science - March 8, 2024 Category: Laser Surgery Source Type: research
Evaluation of combining ultrapulse CO2 with fractional CO2 laser for the treatment of atrophic scars in Asians
AbstractVarious treatment modalities have been applied to atrophic scars. Fractional CO2 laser treatment has attracted increasingly more attention because of its quicker recovery time and fewer side effects. However, its limitation of sculpting the edge is an urgent shortcoming. In order to achieve a more effective result with fewer complications, we have integrated ultrapulse CO2 and fractional CO2 lasers to for the treatment of facial atrophic scars. The study included 25 patients (10 males and 15 females) diagnosed with moderate to severe atrophic scars between August 2020 and July 2022. All subjects underwent the same ...
Source: Lasers in Medical Science - March 8, 2024 Category: Laser Surgery Source Type: research
308 nm excimer laser and tacrolimus ointment in the treatment of facial vitiligo: a systematic review and meta-analysis
This study aimed to investigate the effects and safety of 308 nm excimer laser (308 nm EL) and tacrolimus ointment (TO) in the treatment of facial vitiligo (FV). We searched Cochrane Library, PUBMED, EMBASE, CNKI, and WANGFANG from inception to June 1, 2023. Outcomes included overall response rate (ORR), total adverse reaction rate (TARR), recurrence rate a t 3-month (RR-3) and recurrence rate at 6-month (RR-6). The outcome data were presented as odds ratios (OR) with 95% confidence intervals (CI). The risk of bias was assessed by Cochrane risk-of-bias tool and data analysis was performed by RevMan 5.4 software. This st...
Source: Lasers in Medical Science - March 8, 2024 Category: Laser Surgery Source Type: research
Osteoblastic differentiation and changes in the redox state in pulp stem cells by laser treatment
In conclusion, photobiomodulation (PBM) with LLLT induced morphological changes and reduced cell proliferation rate, which was associated with osteoblastic differentiation and increased ROS a nd Δψm, independent of wavelength and time. (Source: Lasers in Medical Science)
Source: Lasers in Medical Science - March 6, 2024 Category: Laser Surgery Source Type: research
Photobiomodulation preconditioned diabetic adipose derived stem cells with additional photobiomodulation: an additive approach for enhanced wound healing in diabetic rats with a delayed healing wound
AbstractIn this preclinical investigation, we examined the effects of combining preconditioned diabetic adipose-derived mesenchymal stem cells (AD-MSCs) and photobiomodulation (PBM) on a model of infected ischemic delayed healing wound (injury), (IIDHWM) in rats with type I diabetes (TIDM). During the stages of wound healing, we examined multiple elements such as stereology, macrophage polarization, and the mRNA expression levels of stromal cell-derived factor (SDF)-1 α, vascular endothelial growth factor (VEGF), hypoxia-induced factor 1α (HIF-1α), and basic fibroblast growth factor (bFGF) to evaluate proliferation and ...
Source: Lasers in Medical Science - March 5, 2024 Category: Laser Surgery Source Type: research
Influence of Intravascular Laser Irradiation of Blood (ILIB) on inflammatory cytokines and nitric oxide in vivo: a systematic review
AbstractThe use of Intravascular Laser Irradiation of Blood (ILIB) as a treatment or adjunct tool has been used around the world since the 1980s. So that more professionals can deliver benefits to their patients in different areas of health, it is necessary to understand in depth the mechanisms of laser action at the molecular level, for correct indication and success in the treatment. To analyze works that evaluated the influence of ILIB on inflammatory cytokines and nitric oxide (NO) in animals and humans. The literature search was carried out between February and April 2023 in Pubmed, Medline, Web of Science, SciELO, ...
Source: Lasers in Medical Science - March 4, 2024 Category: Laser Surgery Source Type: research
Evaluating the effect of glycerol on increasing the safety and efficiency of hyperthermic laser lipolysis
This study aimed to investigate the effect of glycerol as an Optical Clearing Agent on the temperature profile of the skin during HyperThermic Laser Lipolysis using computer simulation. In this study, a three-layer model of the skin was used to simulate HyperThermic Laser Lipolysis. The Monte Carlo MCML code was used to investigate the propagation of laser photons inside skin tissue. The energy absorbed from photons is used as a heat source to determine the increase in temperature and assess thermal damage in the layers of the skin. The finite element method in COMSOL software was used for calculation. The simulation of si...
Source: Lasers in Medical Science - March 1, 2024 Category: Laser Surgery Source Type: research
Evaluation of changes in macular structures after subthreshold micropulse laser therapy on chronic central serous chorioretinopathy
ConclusionSHML treatment proves to be effective in cCSC eyes, leading to satisfactory recovery of macular structures, especially the photoreceptor layer. (Source: Lasers in Medical Science)
Source: Lasers in Medical Science - February 29, 2024 Category: Laser Surgery Source Type: research
Assessment of clinical efficacy of 445 nm Diode laser as an adjunct to Kirkland flap surgery in the management of periodontitis – a split mouth randomized clinical trial
AbstractAim of this study is to assess the clinical efficacy of 445 nm Diode laser as an adjunct to Kirkland flap surgery in management of periodontitis. Type of study is a Split mouth clinical trial in which a total of 13 patients were recruited based on specific inclusion and exclusion criteria. In each participant, random allocation of selected sites into test and control in contralateral quadrants was done. Clinical parameters such as probing depth and clinical attachment loss was measured in control and test sites using occlusal stents. Flap surgery was carried out 6 weeks after phase I therapy and the selected con...
Source: Lasers in Medical Science - February 28, 2024 Category: Laser Surgery Source Type: research
The effect of photobiomodulation with 830-nm LED on corneal alkali burnt rat model
(Source: Lasers in Medical Science)
Source: Lasers in Medical Science - February 28, 2024 Category: Laser Surgery Source Type: research
