Quantitative phase imaging for characterization of single cell growth dynamics
AbstractQuantitative phase imaging (QPI) has emerged as an indispensable tool in the field of biomedicine, offering the ability to obtain quantitative maps of phase changes due to optical path length delays without the need for contrast agents. These maps provide valuable information about cellular morphology and dynamics, unperturbed by the introduction of exogenous substances. In this review, a summary of recent studies that have focused on elucidating the growth dynamics of individual cells using QPI is presented. Specifically, investigations into cellular changes occurring during mitosis, the differentiation of cellula...
Source: Lasers in Medical Science - October 18, 2023 Category: Laser Surgery Source Type: research
Effectiveness of photobiomodulation for people with age-related cognitive impairment: a systematic review and meta-analysis
AbstractThe increasing incident of age-related cognitive impairment worldwide and the lack of pharmaceutical treatments emphasizes the value of non-pharmaceutical therapy. Emerging evidence suggested photobiomodulation (PBM) is a popular intervention to brain disorder; however, it remains unclear the efficacy of PBM for patients with age-related cognitive impairment. The purpose of this systematic review is to compare the different parameters used in PBM, analyze the beneficial effects of PBM as a potential therapy for age-related cognitive impairment. Five electronic database, PubMed, Web of Science, Cochrane Library, CIN...
Source: Lasers in Medical Science - October 16, 2023 Category: Laser Surgery Source Type: research
The quantitative analysis of low-concentration (2%) ALA-PDT assisted with Q-switch 1064-nm Nd:YAG laser for acne vulgaris treatment
AbstractConventional 5 ‐aminolevulinic acid-photodynamic (ALA-PDT) therapy (10–20%) has been widely applied for moderate-to-severe acne. The aim of this study is to investigate the effects of non-ablative Q-switched 1064-nm Nd:YAG laser-assisted ALA-PDT with low concentration (2%) on the treatment of acne vulgaris. En rolled patients were randomly assigned to 2 groups. One group received combined therapy of 2% ALA-PDT and non-ablative Q-switched 1064-nm Nd:YAG laser, and the other received only 2% ALA-PDT. Patients in each group had received 3-session treatments with 4-week intervals (week 0, 4, and 8). Sebum sec retio...
Source: Lasers in Medical Science - October 16, 2023 Category: Laser Surgery Source Type: research
Wound healing process in beagles after vaporization of the prostate with a novel 200W 450-nm laser
In this study, we investigated whether the novel 200W 450-nm laser system (BR6800, Blueray Medical Ltd., Shaanxi, China) is superior to classic transurethral resection of the prostate (TURP) for wound healing in beagles. Twenty-two 6-to 8-yea r-old male beagles were treated with TURP or blue laser vaporization of the prostate (BLVP). Prostate wounds were observed via cystoscopy at 3 h and at 1, 2, 3, and 5 weeks post-operation (two beagles per group). Additionally, two elderly beagles without surgery served as normal controls. After cy stoscopy examination, prostate samples were collected and fixed for hematoxylin and eo...
Source: Lasers in Medical Science - October 13, 2023 Category: Laser Surgery Source Type: research
Comparison of therapeutic effects of 940 nm diode laser acupuncture with transcutaneous electrical nerve stimulation in the myofascial pain dysfunction syndrome: a comparative randomized clinical trial
This study aimed to compare the clinical efficacy of transcutaneous electrical nerve stimulation (TENS) and laser acupuncture (LA) using a 940-nm diode on MPDS improvement. In this randomized clinical trial, 22 MPDS patients were randomly assigned to TENS (180 HZ, 300 µs, 20 min) and LA (940 nm, continuous wave, 0. 5 w, 40 s, 105 J/cm2) groups. Data on overall facial pain, tenderness in the masticatory muscles, deviation, joint sound, and maximum mouth opening without pain (MMO) were collected from all patients at baseline, before and after each treatment ses sion, and 1 month after the end session. Data were analyzed...
Source: Lasers in Medical Science - October 13, 2023 Category: Laser Surgery Source Type: research
Short-term effects of low-level laser versus ultrasound therapy on children ’s neck posture after long-term use of electronic devices
AbstractThe purpose of the study was to compare the effect of low-level laser therapy (LLLT), ultrasound therapy (US), and strengthening and stretching exercise in children diagnosed with cervical straightening caused by long-term use of electronic devices. A total of 60 patients from 12 to 18 years of both gender diagnosed with straight neck syndrome which is losing the normal C shape of cervical vertebrae. Patients were randomized into three groups. In group A, patients received LLLT plus exercise, while in group B, they received US plus exercise, and group C received exercise. In group A and B, Cobb angle and VAS showed...
Source: Lasers in Medical Science - October 13, 2023 Category: Laser Surgery Source Type: research
Effects of low level laser on periodontal tissue remodeling in hPDLCs under tensile stress
This study aimed to investigate the effect of Low-Level Laser Therapy (LLLT) on human Periodontal Ligament Cells (hPDLCs) under tension stress. Primary hPDLCs were obtained using the tissue culture method, and P3 cells were utilized for the subsequent experiments. The study comprised four groups: a blank control group (Group B), a laser irradiation group (Group L), a tension stress group (Group T), and a laser + tension stress group (Group LT). Mechanical loading was applied using an in-vitro cell stress loading device at a frequency of 0.5 Hz and deformation of 2% for two hours per day for two days. Laser irradiatio...
Source: Lasers in Medical Science - October 11, 2023 Category: Laser Surgery Source Type: research
Correction to: Pulsed transcranial photobiomodulation generates distinct beneficial neurocognitive effects compared with continuous wave transcranial light
(Source: Lasers in Medical Science)
Source: Lasers in Medical Science - October 10, 2023 Category: Laser Surgery Source Type: research
Advancements and prospects of Raman spectroscopy in urological tumors: a bibliometric analysis
This study undertook a bibliometric analysis to chart the present state and future prospects of Raman spectroscopy applications in urological tumors. The present study retrieved literature on the utilization of Raman spectroscopy in urological oncology from the Science Citation Index Expanded of Web of Science Core Collection, spanning from its inception to June 2023. Data from included studies were analyzed using CiteSpace, Python, and Excel. Our study examined 897 articles from 65 countries and identified a significant exponential growth in annual publications. The USA and China were prominent contributors to this field,...
Source: Lasers in Medical Science - October 4, 2023 Category: Laser Surgery Source Type: research
Effectiveness of high-intensity laser application combined with splinting and therapeutic exercise in subacute de Quervain ’s tenosynovitis: A pilot study
AbstractThe purpose of this study is to determine the additional effect of high-intensity laser therapy (HILT) when combined with therapeutic exercise and splinting in the treatment of patients diagnosed with de Quervain ’s tenosynovitis. Nineteen patients diagnosed with de Quervain’s tenosynovitis were randomly divided into two groups: the HILT group and the sham HILT group. A total of 9 HILT or sham HILT sessions were administered, with 3 sessions per week for 3 consecutive weeks. Both groups received the thum b spica splint and therapeutic exercise. A comparison was conducted between the two groups, as well as pre- ...
Source: Lasers in Medical Science - October 3, 2023 Category: Laser Surgery Source Type: research
A systematic review and meta-analysis of efficacy, safety, and satisfaction rates of laser combination treatments vs laser monotherapy in skin rejuvenation resurfacing
AbstractLaser therapies have been well-established in ameliorating skin-aging consequences. This systematic review aims to determine the efficacy, safety profile, and satisfaction rates of laser combination therapies on skin rejuvenation resurfacing. A systematic search was performed in four major databases up to September 2022. Skin rejuvenation studies were eligible comprising at least one laser combination arm, inclusive of all laser types (ablative or non-ablatives), and one monotherapy arm selected from one of the combined modalities. Studies combining one laser modality with radiofrequency (RF) or intense pulse light...
Source: Lasers in Medical Science - September 30, 2023 Category: Laser Surgery Source Type: research
Dual laser-assisted hatching: an effective technique to salvage low-grade cleavage-stage embryos and harvest day 7 blastocysts
AbstractTo investigate whether repeating laser-assisted hatching (LAH) procedure on day 6 low-grade cleavage-stage embryos (LGCEs) helps blastulation. A total of 579 cycles with LGCEs from 2019 to 2022 was retrospectively reviewed. In 323 cycles, single LAH producing small holes (10 μm) was performed on LGCEs on day 4 (D4-LAH). In 256 cycles with persistent LGCEs despite D4-LAH, a repeat LAH procedure was performed on day 6 (Dual-LAH) with a bigger hole (30 μm). We compared day 7 blastocyst formation rate, usable blastocyst rate, and good grade blastocyst rate from these day 6 LGCEs between the two groups. Compared to th...
Source: Lasers in Medical Science - September 30, 2023 Category: Laser Surgery Source Type: research
Comparison of ıntracanal ozone and low-level laser therapy on postoperative pain in vital teeth with symptomatic apical periodontitis:placebo-controlled randomize trial
AbstractThe aim of this study was to compare the effect of ozone and low-level-laser therapy (LLLT) on postoperative pain after root canal treatment in symptomatic apical periodontitis on vital teeth. Eighty patients were divided into four groups using a web program as follows: LLLT placebo (mock laser therapy), LLLT, Ozone placebo (mock ozonated water irrigation), and Ozone. Postoperative pain levels for 7 days after treatment and percussion pain levels at the 7th day were recorded on the visual analog scale. A regression analysis, Cochran ’s Q test, Chi-square test, Kruskal-Wallis tests were performed to analyze the da...
Source: Lasers in Medical Science - September 30, 2023 Category: Laser Surgery Source Type: research
Effect of femtosecond laser-assisted arcuate keratotomy versus toric intraocular lens implantation on correction of astigmatism in cataract surgery: a systematic review and meta-analysis
ConclusionsFSAK combined with non-toric IOL implantation was found to be less effective than TIOL implantation in correcting preoperative corneal astigmatism in cataract patients. The difference in the effectiveness of astigmatism correction between the two surgical methods seems to diminish, as the degree of preoperative corneal astigmatism decreases. (Source: Lasers in Medical Science)
Source: Lasers in Medical Science - September 29, 2023 Category: Laser Surgery Source Type: research
Comparative evaluation of effect of chlorhexidine application on dentin bond strength with two different adhesives after ER, CR: YSGG phototherapy: an in vitro study
This study aimed to assess the efficacy of phototherapy with an Er, Cr:YSGG laser on the bond strength of dentin using two different adhesive systems after chlorhexidine (CHX) application. Twenty-four non-carious human molar teeth were separated into three main groups: negative control Group A (Group A), CHX and phototherapy with an Er, Cr:YSGG laser (Group PC), and CHX with conventional diamond bur (no phototherapy) (Group C). These groups were divided into two subgroups based on adhesives: Clearfil Universal Quick Bond and Clearfil SE Bond. To evaluate the microtensile bond strength, the occlusal enamel surfaces of the t...
Source: Lasers in Medical Science - September 29, 2023 Category: Laser Surgery Source Type: research
