Photobiomodulation at molecular, cellular, and systemic levels
AbstractSince the reporting of Endre Mester ’s results, researchers have investigated the biological effects induced by non-ionizing radiation emitted from low-power lasers. Recently, owing to the use of light-emitting diodes (LEDs), the term photobiomodulation (PBM) has been used. However, the molecular, cellular, and systemic effects invo lved in PBM are still under investigation, and a better understanding of these effects could improve clinical safety and efficacy. Our aim was to review the molecular, cellular, and systemic effects involved in PBM to elucidate the levels of biological complexity. PBM occurs as a cons...
Source: Lasers in Medical Science - June 13, 2023 Category: Laser Surgery Source Type: research
Laser ablation of asphalt and coal in different solvents an In Vitro study
In this study, PLAL is used to prepare nanocolloids of asphalt and coal in different solvents (ethanol, dimethyl sulfoxide (DMSO), phosphate buffer saline (PBS), and distilled water (DW)). A fiber laser of wavelength of 1.06 μm and an average power of 10 watts was used to prepare different nanocolloids in different solvents from asphalt and coal. The cytotoxic effect of the prepared materials was tested against breast cancer MCF7 cell line in vitro. The asphalt in both ethanol and DMSO was found to have a significant cytotoxic effect and the growth inhibition (GI) was found to be 62.1% and 50.5% at concentrations of 620...
Source: Lasers in Medical Science - June 10, 2023 Category: Laser Surgery Source Type: research
Photobiomodulation does not improve anaerobic performance in well-trained cyclists
AbstractTo determine if photobiomodulation (PBM) has ergogenic effects on the anaerobic performance of well-trained cyclists. Fifteen healthy male road or mountain bike cyclists participated in this randomized, double-blinded, placebo-controlled, crossover study. Athletes were randomly assigned to receive photobiomodulation (630 nm, 4.6 J/cm2, 6 J per point, 16 points, PBM session) or placebo intervention (PLA session) in the first session. The athletes then performed a 30-s Wingate test to determine mean and peak average power, relative power, mean and peak velocity, mean and peak RPM, fatigue index, total distance, ...
Source: Lasers in Medical Science - June 9, 2023 Category: Laser Surgery Source Type: research
A systematic review and meta-analysis of efficacy and safety comparing greenlight laser vaporization with transurethral resection of the prostate for benign prostatic hyperplasia with prostate volume less than 80 ml
AbstractWe conducted a meta-analysis to evaluate the efficacy and safety of photo selective vaporisation of the prostate (PVP) with the GreenLight Laser versus transurethral resection of the prostate (TURP) for the treatment of small-volume benign prostatic hyperplasia (BPH). As of July 2022, relevant literature in online databases such as Cochrane Library, PubMed, and Embase was searched, including studies published on or before that date, and th ere were 9 studies in total, including 5 RCTs and 4 non-RCTs. In total 1525 patients were included to compare the efficacy of PVP and TURP in treating BPH. The Cochrane Collabo...
Source: Lasers in Medical Science - June 8, 2023 Category: Laser Surgery Source Type: research
The effectiveness of two types of low-level laser therapy in patients with persistent tinnitus
AbstractTinnitus is a perception disorder of sound with no hearing impulse. It is a very common otology complaint that leads to worsening quality of life. The experience of sound is only the product of neural system activity, with no matching mechanical or vibratory activity in the cochlea, and is unrelated to any external stimuli. Low-level laser therapy (LLLT) is a medical treatment of tinnitus that uses low-energy-level lasers or light-emitting diodes to stimulate or inhibit cellular function. The study included nine patients aged 20 –68 years with unilateral or bilateral tinnitus. It was a self-controlled clinical tr...
Source: Lasers in Medical Science - June 5, 2023 Category: Laser Surgery Source Type: research
A study of the objective benefits and safety of Er-YAG laser in the treatment of genitourinary syndrome of menopause
AbstractThe aim of this study is to evaluate changes in vaginal pH and epithelium maturation after erbium-doped yttrium aluminum garnet (Er-YAG) laser treatment, and to assess its safety and efficacy on the symptoms of genitourinary syndrome of menopause (GSM). This was a retrospective study conducted between November 2019 and April 2022 and included 32 women diagnosed with GSM who had not benefitted from lubrication treatment and could not or would not use estrogen. Patients received three sessions of Er- YAG laser. All patient data before and after treatment were obtained from computer records. Vaginal maturation index (...
Source: Lasers in Medical Science - June 4, 2023 Category: Laser Surgery Source Type: research
Can we predict postinflammatory hyperpigmentation after laser treatment based on dermoscopic findings of solar lentigo?
AbstractSolar
lentigo (SL) commonly occurs as hyperpigmented macules in areas exposed to ultraviolet radiation. It typically shows an increased number of melanocytes in the basal cell layer of the skin, with or without elongated rete ridges. This retrospective study aimed to evaluate the characteristic dermoscopic patterns, reflecting different histopathological features, which might be valuable in predicting the possibility of postinflammatory hyperpigmentation (PIH) occurring after laser treatment. In total, 88 Korean patients diagnosed with biopsy-proven SL (a total of 90 lesions were diagnosed) between January, 201...
Source: Lasers in Medical Science - May 29, 2023 Category: Laser Surgery Source Type: research
Photobiomodulation, alone or combined with adipose-derived stem cells, reduces inflammation by modulation of microRNA-146a and interleukin-1 ß in a delayed-healing infected wound in diabetic rats
AbstractDiabetic wounds are categorized by chronic inflammation, leading to the development of diabetic foot ulcers, which cause amputation and death. Herewith, we examined the effect of photobiomodulation (PBM) plus allogeneic diabetic adipose tissue-derived stem cells (ad-ADS) on stereological parameters and expression levels of interleukin (IL)-1 ß and microRNA (miRNA)-146a in the inflammatory (day 4) and proliferation (day 8) stages of wound healing in an ischemic infected (with 2×107 colony-forming units of methicillin-resistantStaphylococcus aureus) delayed healing wound model (IIDHWM) in type I diabetic (TIDM) rat...
Source: Lasers in Medical Science - May 27, 2023 Category: Laser Surgery Source Type: research
The predictive factors that total laser energy consumed during retrograde intrarenal surgery (RIRS): stone area and density
This study aimed to determine the factors affecting the total laser energy in cases with provided stone-free status after a single session of retrograde intrarenal surgery (RIRS). Data of 222 patients who underwent RIRS between October 2017 and March 2020 were evaluated retrospectively. After exclusion criteria, the study was carried out with 184 stone-free cases. All cases were performed without using a ureteral access sheath (UAS), and dusting was preferred as the lithotripsy method. The effects of age, gender, body mass index (BMI), previous RIRS history, previous shock wave lithotripsy (SWL) history, stone localization...
Source: Lasers in Medical Science - May 26, 2023 Category: Laser Surgery Source Type: research
Comparison of the efficacy of excimer laser coronary angioplasty for ST-segment elevation myocardial infarction with onset-to-balloon time
AbstractExcimer laser coronary angioplasty (ELCA) vaporizes plaques and thrombi, provides better microcirculation, and reduces peripheral embolism when treating acute coronary syndrome. Studies on the efficacy of ELCA for long onset-to-balloon time ST-segment elevation myocardial infarction (STEMI) are limited. Thus, we aimed to examine the efficacy of ELCA for STEMI using the onset-to-balloon time (OBT). A total of 319 patients with STEMI who underwent percutaneous coronary intervention from 2009 to 2012 and from 2015 to 2019 were enrolled. Patients who underwent PCI in 2009 –2012 were considered the conventional group,...
Source: Lasers in Medical Science - May 23, 2023 Category: Laser Surgery Source Type: research
Effects of radial extracorporeal shockwave therapy versus high intensity laser therapy in individuals with plantar fasciitis: A randomised clinical trial
This study aimed to compare the effects of radial extracorporeal shockwave therapy (rESWT) to the effects of high-intensity laser therapy (HILT) in the treatment of individuals with plantar fasciitis. Thirty-two individuals with unilateral plantar fasciitis were randomized into two groups: rESWT and HILT. In each group, the individuals underwent the intervention two sessions per week, for three weeks. Outcome measures included morning pain, resting pain, pain at 80 newtons (N) pressure, skin blood flow and temperature, plantar fascia (PF) and flexor digitorum brevis (FDB) thickness, and Foot Function Index (FFI). There was...
Source: Lasers in Medical Science - May 23, 2023 Category: Laser Surgery Source Type: research
Acne treatment based on selective photothermolysis with topically delivered light-absorbing platinum nanoparticles
(Source: Lasers in Medical Science)
Source: Lasers in Medical Science - May 20, 2023 Category: Laser Surgery Source Type: research
Laser ablation: a unique and beneficial therapeutic option for pilonidal sinus? And the potential for further innovation —a review
AbstractLaser has revolutionized the medical field, broadening the diagnostic and therapeutic spectrum, with diode (630 –980 nm) and Nd:YAG (1064 nm) lasers being the common choices in ablation procedures. Laser ablation in pilonidal sinus disease is a new minimally invasive technique with good treatment efficacy, low post-op morbidity, and shorter recovery periods following employment. This review study aimed to p rovide information on the use of lasers in pilonidal sinus disease and their effectiveness compared to other conventional methods. The articles considered were obtained by performing a literature search in Pub...
Source: Lasers in Medical Science - May 18, 2023 Category: Laser Surgery Source Type: research
Transient apical peak pressure measurement of Er:YAG laser –activated irrigation in different in vitro tooth models using a high-frequency sensor system
In conclusion, tooth anatomy factors and laser parameter settings influenced TAPP during Er:YAG LAI. Therefore, proper settings of laser parameters are important to improve the safety of Er:YAG LAI. (Source: Lasers in Medical Science)
Source: Lasers in Medical Science - May 12, 2023 Category: Laser Surgery Source Type: research
Photothermal treatment of glioblastoma cells based on plasmonic nanoparticles
AbstractPhotothermal therapy based on plasmonic gold nanoparticles is considered a promising approach for cancer treatment. Here, we investigate the in vitro photothermal effect of 30-nm gold nanoparticles, optically excited with a 532-nm continuous laser, on the U87MG malignant glioblastoma cells, and demonstrate the role of nanoparticle concentration and exposure power density in achieving its optimum performance. Laser-induced collective oscillation of electrons in plasmonic gold nanoparticles is employed to generate localized heat to denature tumor cells. Optical spectroscopy is used to measure the plasmonic band of na...
Source: Lasers in Medical Science - May 10, 2023 Category: Laser Surgery Source Type: research
