Re-examination of therapeutic management of muscular dystrophies using a vascular smooth muscle-centered approach
We describe the possible mechanisms of action by which this BRMG helps in alleviating the symptoms of DMD by targeting smooth muscle dystrophin, in addition to its advantages over other therapeutic modalities, as well as how it can serve as a valuable adjunct to existing therapies. We suggest that using BRMG adjuncts that target smooth muscle dystrophin would be a potential therapeutic approach that prolongs the lifespan and extends the duration of ambulation from the onset of DMD. Further studies are needed to validate this hypothesis.PMID:37673649 | PMC:PMC10482562 | DOI:10.1540/jsmr.59.67 (Source: Journal of Smooth Muscle Research)
Source: Journal of Smooth Muscle Research - September 6, 2023 Category: Research Authors: Senthilkumar Preethy Naoki Yamamoto Shiro Osaza Kadalraja Raghavan Vidyasagar Devaprasad Dedeepiya Masaru Iwasaki Samuel Jk Abraham Source Type: research
