Interstitial cells of Cajal in gastrointestinal inflammatory diseases
J Smooth Muscle Res. 2023;59:1-13. doi: 10.1540/jsmr.59.1.ABSTRACTThe gastrointestinal (GI) tract is a vital organ that digests food, absorbs nutrients, and excretes waste. Normal GI motility is the basis for these functions. The interstitial cells of Cajal (ICC) in the GI muscularis layer promote GI motility together with the enteric nervous system and smooth muscle cells. Since GI motility results from complex coordination of these heterogeneous cells, failure of any one of them can lead to GI dysmotility. Knowledge about ICC in physiological conditions has accumulated in recent decades, while the pathophysiology of ICC ...
Source: Journal of Smooth Muscle Research - February 15, 2023 Category: Research Authors: Noriyuki Kaji Masatoshi Hori Source Type: research
Quercetin and resveratrol ameliorate nickel-mediated hypercontraction in isolated Wistar rat aorta
CONCLUSION: In this study, we found that quercetin and resveratrol act as ameliorators of nickel-mediated hypercontraction by decreasing ROS and enhancing NO release from endothelial cells.PMID:36517014 | PMC:PMC9748311 | DOI:10.1540/jsmr.58.89 (Source: Journal of Smooth Muscle Research)
Source: Journal of Smooth Muscle Research - December 14, 2022 Category: Research Authors: Shahnawaz Ahmad Wani Luqman Ahmad Khan Seemi Farhat Basir Source Type: research
