Does obstructive sleep apnea increase the risk of cancer and cancer mortality in combined community-based cohorts?
J Sleep Res. 2023 Nov 21:e14089. doi: 10.1111/jsr.14089. Online ahead of print.ABSTRACTObstructive sleep apnea (OSA) has been linked to cancer in several clinical and community-based cohorts. The effect in community-based studies free of clinical referral bias needs to be replicated. In this observational prospective cohort study, we pooled data from three community-based prospective cohorts (Uppsala Sleep and Health in Men cohort [UMEN]; Sleep and health in women [SHE]; Men Androgen Inflammation Lifestyle Environment and Stress Cohort [MAILES]; nTotal = 1467). All cohorts had objective data on obstructive sleep apnea and ...
Source: Journal of Sleep Research - November 22, 2023 Category: Sleep Medicine Authors: Jenny Theorell-Hagl öw Xingwu Zhou Gary Wittert Robert Adams Sarah Appleton Amy Reynolds Mirjam Ljunggren Nathaniel Marshall Source Type: research
Does obstructive sleep apnea increase the risk of cancer and cancer mortality in combined community-based cohorts?
J Sleep Res. 2023 Nov 21:e14089. doi: 10.1111/jsr.14089. Online ahead of print.ABSTRACTObstructive sleep apnea (OSA) has been linked to cancer in several clinical and community-based cohorts. The effect in community-based studies free of clinical referral bias needs to be replicated. In this observational prospective cohort study, we pooled data from three community-based prospective cohorts (Uppsala Sleep and Health in Men cohort [UMEN]; Sleep and health in women [SHE]; Men Androgen Inflammation Lifestyle Environment and Stress Cohort [MAILES]; nTotal = 1467). All cohorts had objective data on obstructive sleep apnea and ...
Source: Journal of Sleep Research - November 22, 2023 Category: Sleep Medicine Authors: Jenny Theorell-Hagl öw Xingwu Zhou Gary Wittert Robert Adams Sarah Appleton Amy Reynolds Mirjam Ljunggren Nathaniel Marshall Source Type: research
Does obstructive sleep apnea increase the risk of cancer and cancer mortality in combined community-based cohorts?
J Sleep Res. 2023 Nov 21:e14089. doi: 10.1111/jsr.14089. Online ahead of print.ABSTRACTObstructive sleep apnea (OSA) has been linked to cancer in several clinical and community-based cohorts. The effect in community-based studies free of clinical referral bias needs to be replicated. In this observational prospective cohort study, we pooled data from three community-based prospective cohorts (Uppsala Sleep and Health in Men cohort [UMEN]; Sleep and health in women [SHE]; Men Androgen Inflammation Lifestyle Environment and Stress Cohort [MAILES]; nTotal = 1467). All cohorts had objective data on obstructive sleep apnea and ...
Source: Journal of Sleep Research - November 22, 2023 Category: Sleep Medicine Authors: Jenny Theorell-Hagl öw Xingwu Zhou Gary Wittert Robert Adams Sarah Appleton Amy Reynolds Mirjam Ljunggren Nathaniel Marshall Source Type: research
Does obstructive sleep apnea increase the risk of cancer and cancer mortality in combined community-based cohorts?
J Sleep Res. 2023 Nov 21:e14089. doi: 10.1111/jsr.14089. Online ahead of print.ABSTRACTObstructive sleep apnea (OSA) has been linked to cancer in several clinical and community-based cohorts. The effect in community-based studies free of clinical referral bias needs to be replicated. In this observational prospective cohort study, we pooled data from three community-based prospective cohorts (Uppsala Sleep and Health in Men cohort [UMEN]; Sleep and health in women [SHE]; Men Androgen Inflammation Lifestyle Environment and Stress Cohort [MAILES]; nTotal = 1467). All cohorts had objective data on obstructive sleep apnea and ...
Source: Journal of Sleep Research - November 22, 2023 Category: Sleep Medicine Authors: Jenny Theorell-Hagl öw Xingwu Zhou Gary Wittert Robert Adams Sarah Appleton Amy Reynolds Mirjam Ljunggren Nathaniel Marshall Source Type: research
Does obstructive sleep apnea increase the risk of cancer and cancer mortality in combined community-based cohorts?
J Sleep Res. 2023 Nov 21:e14089. doi: 10.1111/jsr.14089. Online ahead of print.ABSTRACTObstructive sleep apnea (OSA) has been linked to cancer in several clinical and community-based cohorts. The effect in community-based studies free of clinical referral bias needs to be replicated. In this observational prospective cohort study, we pooled data from three community-based prospective cohorts (Uppsala Sleep and Health in Men cohort [UMEN]; Sleep and health in women [SHE]; Men Androgen Inflammation Lifestyle Environment and Stress Cohort [MAILES]; nTotal = 1467). All cohorts had objective data on obstructive sleep apnea and ...
Source: Journal of Sleep Research - November 22, 2023 Category: Sleep Medicine Authors: Jenny Theorell-Hagl öw Xingwu Zhou Gary Wittert Robert Adams Sarah Appleton Amy Reynolds Mirjam Ljunggren Nathaniel Marshall Source Type: research
A case of monozygotic twins with hereditary spastic paraplegia type 4 and epilepsy, of whom only one developed narcolepsy type 1
We report a case of monozygotic twin sisters with hereditary spastic paraplegia type 4 (SPG4) and epilepsy, only one of whom had a diagnosis of narcolepsy type 1 (NT1). The older sister with NT1 exhibited excessive daytime sleepiness, cataplexy, sleep-onset rapid eye movement period in the multiple sleep latency test, and decreased orexin levels in cerebrospinal fluid. Both sisters had HLA-DRB1*15:01-DQB1*06:02 and were further identified to have a novel missense mutation (c.1156A > C, p.Asn386His) in the coding exon of the spastin (SPAST) gene. The novel missense mutation might be involved in the development of epileps...
Source: Journal of Sleep Research - November 20, 2023 Category: Sleep Medicine Authors: Yuri Mizuno Taira Uehara Yuri Nakamura Toshiki Okadome Takahiko Mukaino Kishin Koh Yoshihisa Takiyama Takashi Kanbayashi Noriko Isobe Jun-Ichi Kira Hiroyuki Murai Hiroshi Shigeto Source Type: research
Impact of light on task-evoked pupil responses during cognitive tasks
J Sleep Res. 2023 Nov 16:e14101. doi: 10.1111/jsr.14101. Online ahead of print.ABSTRACTLight has many non-image-forming functions including modulation of pupil size and stimulation of alertness and cognition. Part of these non-image-forming effects may be mediated by the brainstem locus coeruleus. The processing of sensory inputs can be associated with a transient pupil dilation that is likely driven in part by the phasic activity of the locus coeruleus. In the present study, we aimed to characterise the task-evoked pupil response associated with auditory inputs under different light levels and across two cognitive tasks. ...
Source: Journal of Sleep Research - November 17, 2023 Category: Sleep Medicine Authors: Islay Campbell Elise Beckers Roya Sharifpour Alexandre Berger Ilenia Paparella Jose Fermin Balda Aizpurua Ekaterina Koshmanova Nasrin Mortazavi Siya Sherif Gilles Vandewalle Source Type: research
Impact of light on task-evoked pupil responses during cognitive tasks
J Sleep Res. 2023 Nov 16:e14101. doi: 10.1111/jsr.14101. Online ahead of print.ABSTRACTLight has many non-image-forming functions including modulation of pupil size and stimulation of alertness and cognition. Part of these non-image-forming effects may be mediated by the brainstem locus coeruleus. The processing of sensory inputs can be associated with a transient pupil dilation that is likely driven in part by the phasic activity of the locus coeruleus. In the present study, we aimed to characterise the task-evoked pupil response associated with auditory inputs under different light levels and across two cognitive tasks. ...
Source: Journal of Sleep Research - November 17, 2023 Category: Sleep Medicine Authors: Islay Campbell Elise Beckers Roya Sharifpour Alexandre Berger Ilenia Paparella Jose Fermin Balda Aizpurua Ekaterina Koshmanova Nasrin Mortazavi Siya Sherif Gilles Vandewalle Source Type: research
Impact of light on task-evoked pupil responses during cognitive tasks
J Sleep Res. 2023 Nov 16:e14101. doi: 10.1111/jsr.14101. Online ahead of print.ABSTRACTLight has many non-image-forming functions including modulation of pupil size and stimulation of alertness and cognition. Part of these non-image-forming effects may be mediated by the brainstem locus coeruleus. The processing of sensory inputs can be associated with a transient pupil dilation that is likely driven in part by the phasic activity of the locus coeruleus. In the present study, we aimed to characterise the task-evoked pupil response associated with auditory inputs under different light levels and across two cognitive tasks. ...
Source: Journal of Sleep Research - November 17, 2023 Category: Sleep Medicine Authors: Islay Campbell Elise Beckers Roya Sharifpour Alexandre Berger Ilenia Paparella Jose Fermin Balda Aizpurua Ekaterina Koshmanova Nasrin Mortazavi Siya Sherif Gilles Vandewalle Source Type: research
Healthcare resource utilisation and costs in patients with treated obstructive sleep apnea
J Sleep Res. 2023 Nov 14:e14099. doi: 10.1111/jsr.14099. Online ahead of print.ABSTRACTObstructive sleep apnea (OSA) is a highly prevalent yet underdiagnosed disease that creates a large economic burden on the United States healthcare system. In this retrospective study, we tested the hypothesis that adherence to positive airway pressure (PAP) therapy, the 'gold standard' treatment for OSA, is associated with reduced healthcare resource utilisation and costs. We linked de-identified payer-sourced medical claims and objective PAP usage data for patients newly diagnosed with OSA. Inverse probability of treatment weighting wa...
Source: Journal of Sleep Research - November 15, 2023 Category: Sleep Medicine Authors: Kimberly L Sterling Naomi Alpert Peter A Cistulli Jean-Louis P épin Suyog More Kate V Cole Atul Malhotra medXcloud group Source Type: research
Sleepiness and comorbid sleep disorders in functional motor disorders: a comparative study with central hypersomnia
This study did not find objective correlates of increased sleepiness in patients with FMD. While sleep abnormalities were found to be common in FMD, they were not correlated with self-reports of excessive sleepiness. Positive correlations between self-reported sleepiness and fatigue support the current unified model of non-motor symptoms in FMD.PMID:37967854 | DOI:10.1111/jsr.14098 (Source: Journal of Sleep Research)
Source: Journal of Sleep Research - November 15, 2023 Category: Sleep Medicine Authors: Ji ří Nepožitek Simona Dost álová Gabriela V ěchetová Tom áš Sieger Zuzana Forejtov á Lucia Nov áková Karol ína Galušková Martin Milata Zs óka Varga Hiroki Tanaka Ev žen Růžička Karel Šonka Mark Edwards Tereza Serranov á Source Type: research
Healthcare resource utilisation and costs in patients with treated obstructive sleep apnea
J Sleep Res. 2023 Nov 14:e14099. doi: 10.1111/jsr.14099. Online ahead of print.ABSTRACTObstructive sleep apnea (OSA) is a highly prevalent yet underdiagnosed disease that creates a large economic burden on the United States healthcare system. In this retrospective study, we tested the hypothesis that adherence to positive airway pressure (PAP) therapy, the 'gold standard' treatment for OSA, is associated with reduced healthcare resource utilisation and costs. We linked de-identified payer-sourced medical claims and objective PAP usage data for patients newly diagnosed with OSA. Inverse probability of treatment weighting wa...
Source: Journal of Sleep Research - November 15, 2023 Category: Sleep Medicine Authors: Kimberly L Sterling Naomi Alpert Peter A Cistulli Jean-Louis P épin Suyog More Kate V Cole Atul Malhotra medXcloud group Source Type: research
Sleepiness and comorbid sleep disorders in functional motor disorders: a comparative study with central hypersomnia
This study did not find objective correlates of increased sleepiness in patients with FMD. While sleep abnormalities were found to be common in FMD, they were not correlated with self-reports of excessive sleepiness. Positive correlations between self-reported sleepiness and fatigue support the current unified model of non-motor symptoms in FMD.PMID:37967854 | DOI:10.1111/jsr.14098 (Source: Journal of Sleep Research)
Source: Journal of Sleep Research - November 15, 2023 Category: Sleep Medicine Authors: Ji ří Nepožitek Simona Dost álová Gabriela V ěchetová Tom áš Sieger Zuzana Forejtov á Lucia Nov áková Karol ína Galušková Martin Milata Zs óka Varga Hiroki Tanaka Ev žen Růžička Karel Šonka Mark Edwards Tereza Serranov á Source Type: research
Healthcare resource utilisation and costs in patients with treated obstructive sleep apnea
J Sleep Res. 2023 Nov 14:e14099. doi: 10.1111/jsr.14099. Online ahead of print.ABSTRACTObstructive sleep apnea (OSA) is a highly prevalent yet underdiagnosed disease that creates a large economic burden on the United States healthcare system. In this retrospective study, we tested the hypothesis that adherence to positive airway pressure (PAP) therapy, the 'gold standard' treatment for OSA, is associated with reduced healthcare resource utilisation and costs. We linked de-identified payer-sourced medical claims and objective PAP usage data for patients newly diagnosed with OSA. Inverse probability of treatment weighting wa...
Source: Journal of Sleep Research - November 15, 2023 Category: Sleep Medicine Authors: Kimberly L Sterling Naomi Alpert Peter A Cistulli Jean-Louis P épin Suyog More Kate V Cole Atul Malhotra medXcloud group Source Type: research
The objective assessment of sleep in cluster headache: State of the art and future directions
J Sleep Res. 2023 Nov 14:e14103. doi: 10.1111/jsr.14103. Online ahead of print.ABSTRACTSeveral lines of evidence suggest that cluster headache is related to chronobiology and sleep. Nevertheless, the nature of such a relationship is unclear. In this view, the objective evaluation of sleep in cluster headache has strong theoretical and clinical relevance. Here, we provide an in-depth narrative review of the literature on objective sleep assessment in cluster headache. We found that only a small number of studies (N = 12) focused on this topic. The key research aims were directed to assess: (a) the relationship between clust...
Source: Journal of Sleep Research - November 14, 2023 Category: Sleep Medicine Authors: Maurizio Gorgoni Giada Giuliani Mariangela Fratino Vittorio Di Piero Source Type: research
