The reimbursement process in three national healthcare systems: variation in time to reimbursement of pembrolizumab for metastatic non-small cell lung cancer
AbstractIn this article, we focus on the reimbursement process, and as an example, characterize the time to reimbursement ofpembrolizumab, a PD-1 immune checkpoint inhibitor for treatment of metastatic NSCLC from publicly available websites, in three different healthcare systems: The National Institute for Health and Care Excellence (NICE) in the UK, the Pharmaceutical Benefits Advisory Committee (PBAC) in Australia, and the National Advisory Committee for the Basket of Health Services in Israel, all who have publicly funded health systems which include drug coverage. Our study found that there are substantial differences ...
Source: Journal of Pharmaceutical Policy and Practice - February 16, 2023 Category: Pharmaceuticals Source Type: research

Public –private partnership alternative for a national pharmacare program in Canada
ConclusionWe show that universal coverage is still possible while leveraging the existing system of private extended health insurance so long as a well-established system for coordinating benefits between public and private payers is established. A stable public/private partnership can achieve universal coverage so long as a system for coordinating benefits is instituted. The proposed alternative will achieve the same goals, but maintain a niche for the private sector thereby maintaining therapeutic variety in the marketplace. (Source: Journal of Pharmaceutical Policy and Practice)
Source: Journal of Pharmaceutical Policy and Practice - February 6, 2023 Category: Pharmaceuticals Source Type: research

Hypertension self-care practice and its associated factors in Bale Zone, Southeast Ethiopia: A multi-center cross-sectional study
ConclusionThe level of good hypertension self-care practice in the study area was low. Hence, it is crucial to expand non-communicable disease control programs and implement public health interventions on self-care for hypertension. Moreover, to enhance hypertension self-care practices, patient-centered interventions are essential. (Source: Journal of Pharmaceutical Policy and Practice)
Source: Journal of Pharmaceutical Policy and Practice - February 2, 2023 Category: Pharmaceuticals Source Type: research

Bridging the gap? Local production of medicines on the national essential medicine lists of Kenya, Tanzania and Uganda
ConclusionsThis study highlights the importance of auditing NDRs and NEMLs for local production to inform regional and national local manufacturing strategies. EMs should be prioritized for local production and drug registration to ensure that production is aligned with local health needs. (Source: Journal of Pharmaceutical Policy and Practice)
Source: Journal of Pharmaceutical Policy and Practice - January 30, 2023 Category: Pharmaceuticals Source Type: research

A quantitative classification of OTC medicines regulations in 30 European countries: dispensing restrictions, distribution, pharmacy ownership, and pricing systems
ConclusionsOur findings point out that OTC medicines are in general not subject to pricing systems, selling is allowed online, and ownership of pharmacies is mostly private. However, regarding dispensing restrictions, pharmacy chains, and establishment restrictions of pharmacies, we found heterogeneity that is also visible in our cluster analysis, since we identified 7 clusters. (Source: Journal of Pharmaceutical Policy and Practice)
Source: Journal of Pharmaceutical Policy and Practice - January 30, 2023 Category: Pharmaceuticals Source Type: research

Community pharmacists ’ perceptions and experiences of stress during COVID-19
ConclusionsWe observed a strong emotional exhaustion in the study sample of pharmacists, who reported high-risk perceptions and fear. A comprehensive assistance should be granted to support the well-being of healthcare workers who provide an essential service, despite the high risk of infection. (Source: Journal of Pharmaceutical Policy and Practice)
Source: Journal of Pharmaceutical Policy and Practice - January 27, 2023 Category: Pharmaceuticals Source Type: research

Alvopem ® (pemetrexed) safety assessment in patients with non-small cell lung cancer or malignant pleural mesothelioma: a post-marketing surveillance
ConclusionsThe results of this open-label, observational PMS showed that Pemetrexed (Alvopem®) is safe in patients with non-squamous NSCLC patients receiving pemetrexed-containing regimens.Trial registration: The trial was registered at ClinicalTrials.gov (NCT04843007) in April 13th, 2021. (Source: Journal of Pharmaceutical Policy and Practice)
Source: Journal of Pharmaceutical Policy and Practice - January 25, 2023 Category: Pharmaceuticals Source Type: research

Community physicians ’ attitudes towards meetings with representatives of pharmaceutical companies: a pilot study
ConclusionThe anticipated heterogeneous attitudes of community-based physicians on interactions with representatives of pharmaceutical companies reflect an inherent complex relationship, with aspects that are specific to the Israeli medical field. Interestingly, physicians trained in other countries than Israel also have divergent attitudes, further affecting the socio-cultural impact on practitioner ’s attitudes towards this intricate and often politicized topic. Open professional dialogue and targeted educational programs on the physician–pharmaceutical relationship, with more explicit regulation, could potentially e...
Source: Journal of Pharmaceutical Policy and Practice - January 25, 2023 Category: Pharmaceuticals Source Type: research

Mental health: “it is a subject where most pharmacists [or pharmacy] students have no more knowledge than the general public”
ConclusionsPharmacy students appreciate the importance of mental health care. The majority recognise the role of the pharmacist in providing person-centred care and the potential to enhance this role. Students are keen to learn more, and acquire the confidence and skills to contribute in the future. They would like an integrated approach and have more opportunities to learn from patients. Addressing stigma is an important consideration for educators. (Source: Journal of Pharmaceutical Policy and Practice)
Source: Journal of Pharmaceutical Policy and Practice - January 24, 2023 Category: Pharmaceuticals Source Type: research

Clinical pharmacists ’ intervention on pain management in cancer patients (PharmaCAP trial): study protocol for a randomized controlled trial
This study protocol outlines two-armed multicenter pilot RCT. Cancer patients suffering from pain will be randomly allocated to receive either clinical pharmacy services, i.e., PharmaCAP trial intervention from the CP, or the usual standard care (i.e., control group). Patients will be recruited consecutively from two hospitals in Kathmandu valley, Nepal. The outcomes will be assessed at baseline (pre-intervention) and 4 weeks post-intervention. The primary feasibility outcomes will include eligibility rate, recruitment rate, willingness to participate, acceptability of screening procedures and random allocation, possible c...
Source: Journal of Pharmaceutical Policy and Practice - January 24, 2023 Category: Pharmaceuticals Source Type: research

A multidisciplinary approach to verify and de-label of drug allergic histories in a university hospital in Thailand: a retrospective descriptive study
ConclusionsMore than half of drug allergic histories were successfully confirmed or de-labeled by the multidisciplinary ADR team. The collaborative activities of various healthcare professionals, consisting of physicians, nurse, and pharmacists as presented in the study were effective in VD services and should be implemented in other healthcare settings. (Source: Journal of Pharmaceutical Policy and Practice)
Source: Journal of Pharmaceutical Policy and Practice - January 20, 2023 Category: Pharmaceuticals Source Type: research

Integration of pharmacist independent prescribers into general practice: a mixed-methods study of pharmacists ’ and patients’ views
ConclusionsPharmacist independent prescribers provide a range of clinical services for the management of long-term conditions which appear to be recognised by patients. However, there is a need to address the barriers to PIPs ’ integration into GP practice to optimise their skill-mix and patient-centred care. (Source: Journal of Pharmaceutical Policy and Practice)
Source: Journal of Pharmaceutical Policy and Practice - January 19, 2023 Category: Pharmaceuticals Source Type: research

Prescribing pattern of antibiotics by family physicians in primary health care
ConclusionThe average number of antibiotics per prescription and the percentage of irrational prescriptions were relatively high in this study. There is need to improve antibiotic prescribing patterns among family physicians working in primary health care. (Source: Journal of Pharmaceutical Policy and Practice)
Source: Journal of Pharmaceutical Policy and Practice - January 19, 2023 Category: Pharmaceuticals Source Type: research

Using Failure Mode, Effect and Criticality Analysis to improve safety in the cancer treatment prescription and administration process
ConclusionsFMECA can be useful for identifying potential failures in a process considered to be at high risk. Safety strategies were devised for each high-risk failure mode identified. (Source: Journal of Pharmaceutical Policy and Practice)
Source: Journal of Pharmaceutical Policy and Practice - January 19, 2023 Category: Pharmaceuticals Source Type: research

Cold chain management practices of non-vaccine commodities in public health facilities of Rwenzori Region, Western Uganda
ConclusionThe management practices for non-vaccine cold chain commodities in health centers were fair. More than a third of the facility store managers lacked knowledge on cold chain management practices for non-vaccine commodities. There is a need to strengthen the capacity of the facilities ’ store managers and provide equipment specific for non-vaccine cold chain commodities. (Source: Journal of Pharmaceutical Policy and Practice)
Source: Journal of Pharmaceutical Policy and Practice - January 18, 2023 Category: Pharmaceuticals Source Type: research