Giant tuberculomas of brain: Rare neoplastic mimic
Conclusion: To the best of our knowledge, this is the largest series of giant tuberculoma in the pediatric population reported so far in any part of the world. We have described the various MRI imaging findings of this lesion in great details. Management of such rare cases and pertinent literature is reviewed briefly. (Source: Journal of Pediatric Neurosciences)
Source: Journal of Pediatric Neurosciences - November 6, 2020 Category: Neuroscience Authors: Chandradev Sahu Nishant Bhargava Vivek Singh Pranav Dwivedi Source Type: research
Normative reference value for tactile localization acuity among school-going children: A normative research
Conclusion: Normative reference values of TL acuity have been established among school-going children between 8 and 13 years. (Source: Journal of Pediatric Neurosciences)
Source: Journal of Pediatric Neurosciences - November 6, 2020 Category: Neuroscience Authors: Krati Omar Asir John Samuel Source Type: research
Neonatal seizures and future epilepsy: Predictive value of perinatal risk factors, electroencephalography, and imaging
Conclusion: Although there are recent promising and advanced techniques in neonatal intensive care units, asphyxia is still one of the most important risk factors for not only poor neurological conditions but also for future epilepsy after neonatal seizures. Apgar scores, treatment with multiple antiepileptic drugs, poor background EEG activity, and abnormal neuroimaging seem to have strong predictive values for developing subsequent epilepsy. Therefore, patients with a history of neonatal seizures should be closely followed up to decrease the risk of long-term outcomes and early detection of epilepsy. (Source: Journal of ...
Source: Journal of Pediatric Neurosciences - November 6, 2020 Category: Neuroscience Authors: Tugba Hirfanoglu Zeynep Ozturk Guntulu Sahin Gokdogan Ibrahim Murat Hirfanoglu Eray Esra Onal Canan Turkyilmaz Ebru Ergenekon Esin Koc Source Type: research
Holocord tanycytic ependymoma: An interesting case with unusual presentation, challenging histological diagnosis, and single-staged complete tumor resection
Suresh K Sankhla, Ghulam M KhanJournal of Pediatric Neurosciences 2020 15(3):183-189An interesting case of intramedullary holocord cystic tumor in an 11-year old boy is reported, who presented with unusual clinical manifestations and radiological features. Gross total resection of the tumor was performed in a single-staged surgery. A rare combination of unusual presentation, uncommon histopathological findings, and challenges in the selection of surgical options were discussed with a detailed review of the literature. (Source: Journal of Pediatric Neurosciences)
Source: Journal of Pediatric Neurosciences - November 6, 2020 Category: Neuroscience Authors: Suresh K Sankhla Ghulam M Khan Source Type: research
Medulloblastoma under siege: Genetic and molecular dissection concerning recent advances in therapeutic strategies
Zeal D Rawal, Vinal A Upadhyay, Dipak D Patel, Trupti I TrivediJournal of Pediatric Neurosciences 2020 15(3):175-182Medulloblastoma (MB) is a devastating illness with unmet therapeutic needs, predominantly cytotoxic and nontargeted approaches. Survivors of MB also suffer from severe treatment-related effects of radiation and cytotoxic chemotherapy keeping mortality rate significant. Recently, four distinct molecular subgroups of MB have been identified (WNT [wingless], SHH [sonic hedgehog], Group 3, and Group 4). Novel subgroup-specific therapies are being explored in the daily treatment of patients as a clinical trial and...
Source: Journal of Pediatric Neurosciences - November 6, 2020 Category: Neuroscience Authors: Zeal D Rawal Vinal A Upadhyay Dipak D Patel Trupti I Trivedi Source Type: research
Rare presentations of spontaneous spinal epidural hematomas in children
Smita Ramachandran, Varsha Mishra, Rani GeraJournal of Pediatric Neurosciences 2020 15(3):171-174Spontaneous spinal epidural hematomas are a rare presentation in children with very few case reports of spontaneous spinal hemorrhage in the pediatric age-group. There has to be a high index of suspicion of spontaneous spinal bleed in patients with acute-onset quadriparesis with no prior history of bleeding or trauma, as early diagnosis and surgical decompression is associated with better neurological outcomes. (Source: Journal of Pediatric Neurosciences)
Source: Journal of Pediatric Neurosciences - November 6, 2020 Category: Neuroscience Authors: Smita Ramachandran Varsha Mishra Rani Gera Source Type: research
Sitting position for posterior fossa tumor in infants: A technical report
Dattatraya Muzumdar, Shyle Mehta, Dikpalsingh JadhavJournal of Pediatric Neurosciences 2020 15(3):169-170Surgery for posterior fossa tumors in sitting position is performed in very few neurosurgical centers all over the world. It carries the potential risk of air embolism with consequent related morbidity. However, posterior fossa surgery in the sitting position is still performed in neurosurgical centers with considerable expertise including neurosurgeons and neuroanesthesiologists. In older children and young adults, the sitting position is given with the appropriate modifications in the operating surgical table and the ...
Source: Journal of Pediatric Neurosciences - November 6, 2020 Category: Neuroscience Authors: Dattatraya Muzumdar Shyle Mehta Dikpalsingh Jadhav Source Type: research
James Goodrich: A personal tribute
Sandip ChatterjeeJournal of Pediatric Neurosciences 2020 15(2):166-167 (Source: Journal of Pediatric Neurosciences)
Source: Journal of Pediatric Neurosciences - June 29, 2020 Category: Neuroscience Authors: Sandip Chatterjee Source Type: research
Autism spectrum disorder and mammalian target of rapamycin system
Annio Posar, Paola ViscontiJournal of Pediatric Neurosciences 2020 15(2):164-165 (Source: Journal of Pediatric Neurosciences)
Source: Journal of Pediatric Neurosciences - June 29, 2020 Category: Neuroscience Authors: Annio Posar Paola Visconti Source Type: research
West syndrome and neurocutaneous syndromes: A never-ending association
Singanamalla Bhanudeep, Priyanka Madaan, Niteesh Bharadwaj, Lokesh Saini, Dipankar DeJournal of Pediatric Neurosciences 2020 15(2):162-163 (Source: Journal of Pediatric Neurosciences)
Source: Journal of Pediatric Neurosciences - June 29, 2020 Category: Neuroscience Authors: Singanamalla Bhanudeep Priyanka Madaan Niteesh Bharadwaj Lokesh Saini Dipankar De Source Type: research
Amniotic band syndrome with placenta & #8211;encephalocele adhesion: An uncommon case
Aldo Jose Ferreira da SilvaJournal of Pediatric Neurosciences 2020 15(2):160-161Amniotic band syndrome is a rare condition that is associated with various malformations. Its etiology is controversial. The neuroimage shown here is of a newborn with placenta–encephalocele adhesion and other malformations that suggest amniotic band syndrome. (Source: Journal of Pediatric Neurosciences)
Source: Journal of Pediatric Neurosciences - June 29, 2020 Category: Neuroscience Authors: Aldo Jose Ferreira da Silva Source Type: research
A rare case report of Guillain & #8211;Barr & #233; syndrome presenting as unilateral facial palsy with isolated acute bulbar palsy
Prachi Yadav, Sahil Dhaka, Richa Chaudhary, Sachin Damke, Sham LohiyaJournal of Pediatric Neurosciences 2020 15(2):157-159Guillain–Barré syndrome (GBS) is an immune-mediated acute inflammatory polyradiculoneuropathy and it is the most common cause of acute flaccid paralysis worldwide. There are some rare variants of GBS, which may be easily missed unless suspected. Here we present a case of GBS presenting as isolated acute bulbar palsy. A 10-month-old infant, known case of tricuspid atresia with pulmonary stenosis, presented with left-sided lower motor neuron type of facial palsy and palsy of bilat...
Source: Journal of Pediatric Neurosciences - June 29, 2020 Category: Neuroscience Authors: Prachi Yadav Sahil Dhaka Richa Chaudhary Sachin Damke Sham Lohiya Source Type: research
A rare case of peripheral nerve hyperexcitability in childhood: Isaacs syndrome
We present a 13-year-old girl with muscle stiffness and neuromyotonia diagnosed Isaac syndrome with spontaneous discharge potentials on motor unit in electromyography and the diagnosis supported by the presence of antinuclear antibodies. A successful treatment was obtained using low-dose carbamazepine. Cause of Isaacs syndrome is unknown, generally thought to be an autoimmune etiology with voltage-gated potassium channelopathy; it sometimes occurs as a paraneoplastic syndrome. Early use of electromyography has critical role in the differential diagnosis with certain muscle disorders and peripheral nerve hyperexcitability s...
Source: Journal of Pediatric Neurosciences - June 29, 2020 Category: Neuroscience Authors: Seda Kanmaz Muhittin Ozcan Erdem Simsek Hepsen M Serin Ibrahim Aydogdu Sarenur Gokben Hasan Tekgul Source Type: research
Cerebral venous sinus thrombosis following primary varicella infection in a child
Leema P Cornelius, Vivekasaravanan Raju, Asir J PaulrajJournal of Pediatric Neurosciences 2020 15(2):150-152Varicella infection commonly called chicken pox is a benign self-limiting infection in children. Neurological complications following varicella infection are rare. Cerebral venous sinus thrombosis following varicella infection is very rare. Herewith we report a child who developed transverse and sigmoid sinus thrombosis following chicken pox. (Source: Journal of Pediatric Neurosciences)
Source: Journal of Pediatric Neurosciences - June 29, 2020 Category: Neuroscience Authors: Leema P Cornelius Vivekasaravanan Raju Asir J Paulraj Source Type: research
A rare case of intramedullary lipoma of brainstem to thoracic cord & #8211; & #8211;What to do ?
Conclusion: Such lipoma needs extensive pre-, intra-, and postoperative planning. The goal should be decompression, rather than excision. Outcome is good with partial resection. (Source: Journal of Pediatric Neurosciences)
Source: Journal of Pediatric Neurosciences - June 29, 2020 Category: Neuroscience Authors: Ishu Bishnoi Pardaman Singh Geetika Duggal Sunil Sorout Source Type: research
