Anomalous craniovertebral junction (CVJ) anomalies in pediatric population: Impact of digital three-dimensional animated models in enhancing the surgical decision-making
Jayesh Sardhara, Suyash Singh, Arun Kumar Srivastava, Sanjay BehariJournal of Pediatric Neurosciences 2021 16(3):175-181 (Source: Journal of Pediatric Neurosciences)
Source: Journal of Pediatric Neurosciences - June 3, 2022 Category: Neuroscience Authors: Jayesh Sardhara Suyash Singh Arun Kumar Srivastava Sanjay Behari Source Type: research

Bilateral calf hypertrophy and isolated motor delay: think beyond muscular dystrophy
Ijas Hassan, Singanamalla Bhanudeep, Priyanka Madaan, Monika Chhajed, Lokesh SainiJournal of Pediatric Neurosciences 2021 16(2):173-174 (Source: Journal of Pediatric Neurosciences)
Source: Journal of Pediatric Neurosciences - December 3, 2021 Category: Neuroscience Authors: Ijas Hassan Singanamalla Bhanudeep Priyanka Madaan Monika Chhajed Lokesh Saini Source Type: research

Airway management of a giant encephalocele using mega pillow
Sunaakshi Puri, Rajeev Chauhan, Rashi Sarna, Summit D BloriaJournal of Pediatric Neurosciences 2021 16(2):170-172 (Source: Journal of Pediatric Neurosciences)
Source: Journal of Pediatric Neurosciences - December 3, 2021 Category: Neuroscience Authors: Sunaakshi Puri Rajeev Chauhan Rashi Sarna Summit D Bloria Source Type: research

Brain abscess due to Enterobacter sakazakii in a neonate
Srinivasan Sreeramulu Uddanapalli, Hamood Ali AlSheulliJournal of Pediatric Neurosciences 2021 16(2):168-169 (Source: Journal of Pediatric Neurosciences)
Source: Journal of Pediatric Neurosciences - December 3, 2021 Category: Neuroscience Authors: Srinivasan Sreeramulu Uddanapalli Hamood Ali AlSheulli Source Type: research

Spontaneous calvarial regeneration following decompressive craniectomy obviating need for cranioplasty: A serendipitous occurrence
Dimble Raju, Grandhi Aditya, Abhijit Ray, Nabanita Ghosh, Prasad KrishnanJournal of Pediatric Neurosciences 2021 16(2):165-167 (Source: Journal of Pediatric Neurosciences)
Source: Journal of Pediatric Neurosciences - December 3, 2021 Category: Neuroscience Authors: Dimble Raju Grandhi Aditya Abhijit Ray Nabanita Ghosh Prasad Krishnan Source Type: research

An unusual case of a conus hanging by a thread
We report a rare cause of paraparesis in a 2-year-old girl. Along with lower limb weakness, she presented with a neurogenic bladder and lower limb deformities. Her magnetic resonance imaging showed multiple dorsolumbar segmentation defects and a dysgenetic spinal cord segment between T10 and S1. A thin septum connected the lower end of the normal cord to a bulky conus at S1-2. These features were suggestive of type 1 segmental spinal dysgenesis. The findings were confirmed at surgery, and the child was referred for supportive care. (Source: Journal of Pediatric Neurosciences)
Source: Journal of Pediatric Neurosciences - December 3, 2021 Category: Neuroscience Authors: Panikar Wadhera Saritha Aryan Sumit Thakar Source Type: research

Cyclosporine-induced leukoencephalopathy precipitated following interaction with ciprofloxacin
Divya Nagabushana, Supraja Chandrasekhar, Stalin Ramprakash, Gurudutt Avathi Venkatesha, Rajesh V HelavarJournal of Pediatric Neurosciences 2021 16(2):161-162A bone marrow transplant recipient on cyclosporine initiated on ciprofloxacin for a renal abscess presented with encephalopathy, right hemiparesis, and multiorgan dysfunction. Imaging revealed white matter signal changes characteristic of cyclosporine leukoencephalopathy. This case illustrates the potential drug interaction of cyclosporine with ciprofloxacin and the need to exercise caution while prescribing antibiotics with cyclosporine. (Source: Journal of Pediatric Neurosciences)
Source: Journal of Pediatric Neurosciences - December 3, 2021 Category: Neuroscience Authors: Divya Nagabushana Supraja Chandrasekhar Stalin Ramprakash Gurudutt Avathi Venkatesha Rajesh V Helavar Source Type: research

Posttraumatic pseudoaneurysm of extracranial internal carotid artery presenting as massive oropharyngeal bleed with shock and hemiparesis in a 12-year-old boy: A case report
We present a 12-year-old previously healthy child with recurrent oropharyngeal hemorrhage leading to massive hematemesis and hypovolemic shock due to right-sided internal carotid artery pseudoaneurysm with hemorrhage and right middle cerebral artery territory infarct. The child required urgent endovascular stenting with decompressive craniectomy for life-threatening intracranial bleeding with herniation with near-complete recovery. (Source: Journal of Pediatric Neurosciences)
Source: Journal of Pediatric Neurosciences - December 3, 2021 Category: Neuroscience Authors: Ramaning Loni Archana Addanki Rakesh Ranjan Sambhaji Pawal Priya Mankare Rajesh Source Type: research

Rapidly progressive spastic paraplegia due to hyperhomocysteinemia in child with MTHFR gene mutation and mitochondrial Complex I deficiency: A rare association
We report a 10-year-old girl with rapidly progressive spastic paraplegia requiring wheelchair ambulation within 3 months of symptom onset with behavioral disturbances. Plasma homocysteine and plasma lactate were high with normal vitamin B12 levels. Clinical exome sequencing showed homozygous missense mutation in MTHFR gene which was likely pathogenic variant. Respiratory chain complex assay from muscle sample showed reduced complex 1 deficiency (<20%). (Source: Journal of Pediatric Neurosciences)
Source: Journal of Pediatric Neurosciences - December 3, 2021 Category: Neuroscience Authors: Rohan R Mahale Jyothi Gautam Gautam Arunachal Sandhya Alappati Nibu Varghese Jennifer Kovoor Pooja Mailankody Hansashree Padmanabha Mathuranath Pavagada Source Type: research

Familial global developmental delay secondary to & #946;-mannosidosis
Vykuntaraju K Gowda, Balamurugan Nagarajan, Srividya G Suryanarayana, Varunvenkat M SrinivasanJournal of Pediatric Neurosciences 2021 16(2):149-152β-Mannosidosis is a rare lysosomal storage disorder that is caused by a deficiency of β-mannosidase activity, which is due to mutations of the MANBA gene. Two Indian siblings born out of a third-degree consanguineous marriage presented during late infancy with global developmental delay. On examination, both the siblings had hypotonia; hepatosplenomegaly was present in the first sibling whereas it was absent in the second sibling. Fundus evaluation, heari...
Source: Journal of Pediatric Neurosciences - December 3, 2021 Category: Neuroscience Authors: Vykuntaraju K Gowda Balamurugan Nagarajan Srividya G Suryanarayana Varunvenkat M Srinivasan Source Type: research

Bacteriological profile and antimicrobial susceptibility pattern of cerebrospinal fluid shunt infections in infants and children
Conclusion: Most common organisms isolated were A. baumannii followed by E. faecalis. Carbapenem resistance was noted in these isolates which were sensitive to colistin. All Gram-positive isolates were sensitive to vancomycin and linezolid. (Source: Journal of Pediatric Neurosciences)
Source: Journal of Pediatric Neurosciences - December 3, 2021 Category: Neuroscience Authors: Ankita Chaurasia Alka Shinde Sujata Baveja Source Type: research

Brain perfusion, hippocampal volumetric, and diffusion-weighted imaging findings in children with prolonged febrile seizures and focal febrile seizures
Conclusion: Children with FSE and FFS had comparable hippocampal volume and brain perfusion to healthy children. However, one child with FSE had hippocampal malrotation and another had diffusion restriction. The study findings need to be interpreted in the context of small sample size, and lack of follow-up neuroimaging. (Source: Journal of Pediatric Neurosciences)
Source: Journal of Pediatric Neurosciences - December 3, 2021 Category: Neuroscience Authors: Seema Rohilla Aditya Duhan Kiran Bala Jaya Shankar Kaushik Source Type: research

Effects of long-term antiepileptic therapy on carotid artery intima-media thickness
Conclusion: Children on long-term monotherapy with valproate, phenytoin, and levetiracetam have significantly abnormal CIMT. This might be associated with atherosclerotic changes, and these children may require close follow-up to prevent cardiovascular and cerebrovascular risks. (Source: Journal of Pediatric Neurosciences)
Source: Journal of Pediatric Neurosciences - December 3, 2021 Category: Neuroscience Authors: Vipul U Kolekar Seema P Sindgikar Raghuraj Uppoor Dhrithiman Shetty KM Vijaya Shenoy Source Type: research

How important is to know the psychosocial performance in an operated child of meningioma ? Devil is in the details
Conclusion: The discontinuation in schooling or lack of alternative education may lead to poor MISIC scores, wrongly categorizing the children in poor IQ group. In pediatric benign disease such as meningioma, the holistic approach should be opted from the time of first visit to neurological care team. (Source: Journal of Pediatric Neurosciences)
Source: Journal of Pediatric Neurosciences - December 3, 2021 Category: Neuroscience Authors: Bhawan Nangarwal Suyash Singh Shruti Sinha Kamlesh S Bhaisora Jayesh Sardhara Kuntal K Das Anant Mehrotra Arun K Srivastava Shakti Desh Awadhesh K Jaiswal Sanjay Behari Source Type: research

Childhood hydrocephalus in Sokoto: Experience with 401 series
Conclusion: Poverty and illiteracy were strongly associated with childhood hydrocephalus in our patients. Infection was predominantly associated with morbidity with large number of patients being lost to follow-up. (Source: Journal of Pediatric Neurosciences)
Source: Journal of Pediatric Neurosciences - December 3, 2021 Category: Neuroscience Authors: Henry Olayere Obanife Jinjiri Ismail Nasiru Ali Lasseini Otorkpa Joseph Ega Bello Bala Shehu Source Type: research