Continuous intradialytic amino acid infusion from the start of dialysis is better to avoid catabolism under the high-volume pre-dilution on-line HDF
AbstractIt was reported that amino acid infusion during hemodialysis is useful for improving nutritional status. The optimal administration method of amino acid infusion under the high-volume pre-dilution on-line HDF (HVPO-HDF) was analyzed in this study. Subjects were 10 patients on maintenance dialysis at our clinic. We performed high-volume pre-dilution on-line HDF. We investigated two methods for administration of Neoamiyu® 200-ml total amino acid (TAA) infusion for patients with renal failure: (1) continuous infusion into the dialysis circuit for 4 h from the start of dialysis to its completion (infusion rate 50 m...
Source: Journal of Artificial Organs - December 1, 2022 Category: Transplant Surgery Source Type: research
Comprehensive analysis of cytokine adsorption properties of polymethyl methacrylate (PMMA) membrane material
In this study, we comprehensively analyzed the adsorption of 48 different cytokines in human plasma to PMMA and polysulfone (PS) membranes. Seventy-nine percent (38/48) of the cytokines were adsorbed more efficiently to the PMMA membrane than the PS membrane, which indicates that the PMMA membrane has high cytokine adsorption ability. The adsorption rate tended to be higher for the cytokines with lower molecular weight, and there was a significant correlation between the molecular weight of the cytokines and the adsorption rates. Electron microscopy showed that the PMMA hollow fiber membrane had a uniform internal structur...
Source: Journal of Artificial Organs - December 1, 2022 Category: Transplant Surgery Source Type: research
Hemodynamic performance of INSPIRIS RESILIA aortic bioprosthesis for severe aortic stenosis: 2-year follow-up in Japanese cohort
AbstractThe INSPIRIS RESILIA aortic bioprosthesis (Edwards Lifesciences LLC, Irvine, USA) was fixed in novel tissue preservation technology to ensure long-term durability. Hemodynamic performance after aortic valve replacement (AVR) for severe aortic stenosis (AS) has not been published in the Japanese cohort. Twenty-nine patients underwent AVR with INSPIRIS RESILIA bioprosthesis for severe AS between November 1, 2018 and December 31, 2020. The mean age was 75.1 ± 4.5 years with 19 female patients. Body surface area was 1.58 ± 0.19 m2 and New York Heart Association functional class was 2.2 ± 0.5. Hemodyna...
Source: Journal of Artificial Organs - December 1, 2022 Category: Transplant Surgery Source Type: research
Simultaneous electrical online estimation of changes in blood hematocrit and temperature in cardiopulmonary bypass
AbstractTwo equations have been developed from multi-frequency measurements of blood impedanceZb for a simultaneous electrical online estimation of changes in blood hematocritΔH [%] and temperaturesΔT [K] in cardiopulmonary bypass (CPB).Zb of fixed blood volumes at varyingH andT were measured by an impedance analyzer and changes in blood conductivityσb and relative permittivityεb computed. Correlation analysis were based on changes inσb withH orT atf = 1 MHz whileH andT equations were developed by correlating changes inεb withH andT at dual frequencies off = 1 MHz andf = 10 MHz which best capture blood...
Source: Journal of Artificial Organs - December 1, 2022 Category: Transplant Surgery Source Type: research
Nerve regeneration using the Bio 3D nerve conduit fabricated with spheroids
We reported the first application of the Bio 3D nerve conduit for peripheral nerve injury. A Bio 3D nerve conduit that was created from several cells promotes peripheral nerve regeneration. The Bio 3D nerve conduit may be useful clinically to treat peripheral nerve defects. (Source: Journal of Artificial Organs)
Source: Journal of Artificial Organs - December 1, 2022 Category: Transplant Surgery Source Type: research
Replication of fouling in vitro in hollow fiber dialyzers by albumin immobilization
AbstractFor designing and evaluating the dialyzer and investigating the optimal therapeutic conditions, in vitro studies bring us many useful findings. In hemodialysis, however, the membrane fouling due to protein molecules reduces solute removal performance. Therefore, we investigated a method for replicating the fouling in dialyzers in aqueous experiments. After the albumin solution was circulated in the test circuit with a dialyzer, a glutaraldehyde solution was pumped into the dialyzer to immobilize albumin on the hollow fiber membrane. Under various immobilization conditions, the permeability of creatinine and vitamin...
Source: Journal of Artificial Organs - December 1, 2022 Category: Transplant Surgery Source Type: research
Anterior leaflet-oriented tricuspid annuloplasty using a flexible ring for severe tricuspid regurgitation
We describe our concept and method of tricuspid annuloplasty using flexible ring for patients with severe tricuspid regurgitation accompanied by a severe tethering and a wide separation of the leaflets between the anterior leaflet and septal leaflet. The goal for our tricuspid ring annuloplasty using a flexible ring is to match the patient ’s own anterior leaflet configuration. We reduce the size of the tricuspid annulus respecting the individual configuration of the anterior leaflet to create a sufficient coaptation area of the leaflets. We performed this method in a 78-year-old female patient with very severe tricuspid...
Source: Journal of Artificial Organs - December 1, 2022 Category: Transplant Surgery Source Type: research
Sudden severe left ventricular assist device inflow cannula obstruction caused by huge thrombus after closure of mechanical aortic valve: case report
AbstractThrombus formation is a troublesome and sometimes lethal complication occurring in patients with severe heart failure and supported by a left ventricular assist device (LVAD). Appropriate treatment for pump thrombosis especially in emergency cases with severe pump failure is difficult to choose. Herein, we present important findings of a case of unexpected LVAD pump thrombosis that rapidly developed into serious pump failure and circulatory arrest due to total obstruction of the LVAD inflow tract by a huge thrombus. (Source: Journal of Artificial Organs)
Source: Journal of Artificial Organs - December 1, 2022 Category: Transplant Surgery Source Type: research
Impella 5.0 support as a bridge to the exchange of an infected left ventricular assist device
AbstractA pump infection is a fatal complication specific to left ventricular assist devices. Infection recurrence is a major concern when device exchange is indicated for pump infection. In the present case, we used the Impella 5.0 to maintain proper hemodynamics and to treat the infection in the absence of an implantable device. We demonstrate that the Impella 5.0 can serve as an effective bridge for device exchange by controlling infection and minimizing organ dysfunction, despite prolonged management. (Source: Journal of Artificial Organs)
Source: Journal of Artificial Organs - December 1, 2022 Category: Transplant Surgery Source Type: research
Reconfiguration from veno-arterial to veno-arterio-venous extracorporeal membrane oxygenation for massive pulmonary embolism
AbstractDifferential hypoxia may occur after the initiation of femorofemoral veno-arterial extracorporeal membrane oxygenation (VA ECMO) if cardiac function improves while severe respiratory failure is still present, one of the most difficult problems encountered during VA ECMO. Reconfiguration to veno-arterio-venous ECMO (V-AV ECMO) is one of several methods of dealing with differential hypoxia. V-AV ECMO requires triple cannulation and careful management of the reinjection flow, but the risk of bleeding is lower than in a surgical procedure, such as central ECMO or a subclavian artery graft. Herein, we reported a patient...
Source: Journal of Artificial Organs - December 1, 2022 Category: Transplant Surgery Source Type: research
Successful trans-femoral retrieval of a stuck axillary Impella 5.0 device
We describe a case in which an axillary Impella 5.0, stuck in an area of calcification in the right subclavian artery, could not be retrieved in the usual manner. However, it was successfully removed using a long 22-Fr sheath and snaring catheter by means of the trans-femoral artery. Device retrieval using the trans-femoral artery snare technique is considered a valid option for removing the Impella device in patients who exhibit this complication. (Source: Journal of Artificial Organs)
Source: Journal of Artificial Organs - November 27, 2022 Category: Transplant Surgery Source Type: research
Central extracorporeal membrane oxygenation with left-ventricular vent for fulminant myocarditis: a retrospective study
ConclusionsCentral ECMO with an LV vent was effective for fulminant myocarditis refractory to percutaneous cardiopulmonary support therapy and other therapies. (Source: Journal of Artificial Organs)
Source: Journal of Artificial Organs - November 8, 2022 Category: Transplant Surgery Source Type: research
Correction to: In memoriam of Dr. Hisateru Takano
(Source: Journal of Artificial Organs)
Source: Journal of Artificial Organs - October 26, 2022 Category: Transplant Surgery Source Type: research
