A pilot clinical trial of a self-management intervention in patients with a left ventricular assist device
AbstractSelf-management is a health behavior known to predict treatment outcomes in patients with multiple co-morbidities and/or chronic conditions. However, the self-management process and outcomes in the left-ventricular assist device (LVAD) population are understudied. This pilot randomized control trial (RCT) evaluated the feasibility of a novel “smartphone app-directed and nurse-supported self-management intervention” in patients implanted with durable LVADs. Assessments includedbehavioral (self-efficacy and adherence),clinical (complications), andhealthcare utilization (unplanned clinic, emergency room (ER) visit...
Source: Journal of Artificial Organs - June 1, 2022 Category: Transplant Surgery Source Type: research

Multiple organ retrieval in a brain dead left ventricular assist device donor
We report on intra-abdominal organs procurement strategy in a selected LVAD recipient who suffered a fatal cerebrovascular accident at the time of COVID-19 pandemic outbreak. The liver and kidneys grafts have been successfully transplanted. (Source: Journal of Artificial Organs)
Source: Journal of Artificial Organs - June 1, 2022 Category: Transplant Surgery Source Type: research

Absent right superior vena cava with persistent left superior vena cava in a patient with COVID-19
We report the case of a patient with coronavirus disease (COVID-19) who was expected to undergo ECMO. By performing computed tomography (CT), we identified the absence of right superior vena cava (RSVC) with a persistent left superior vena cava (PLSVC) that could have caused serious complications associated with ECMO cannulation. PLSVC is observed in less than 0.5% of the general population; however, the combination of PLSVC and an absent RSVC in visceroatrial situs solitus is extremely rare. Attempting cannulation for Veno-venous (VV)-ECMO from the right (or left) internal jugular vein to the right atrium may cause seriou...
Source: Journal of Artificial Organs - June 1, 2022 Category: Transplant Surgery Source Type: research

Surgical revision of failed MitraClip procedure for atrial functional mitral regurgitation
AbstractThe MitraClip system is used for patients with severe mitral regurgitation (MR) who are at high risk for open surgery. However, some patients need surgical revision for various complications. The acute outcome of MitraClip treatment for atrial functional MR (aFMR) is scarcely reported. Herein, we describe a rare case of an 80-year-old woman treated with a MitraClip for aFMR with mitral annular dilatation and failed leaflet adaptation. The patient suffered from single leaflet device attachment (SLDA) and posterior leaflet injury 3 days posttreatment. The patient successfully underwent mitral valve replacement. The p...
Source: Journal of Artificial Organs - June 1, 2022 Category: Transplant Surgery Source Type: research

Flexion limitation of the Impella 5.0 when implanted using the femoral approach in patients with small stature
(Source: Journal of Artificial Organs)
Source: Journal of Artificial Organs - June 1, 2022 Category: Transplant Surgery Source Type: research

Current status of antimicrobial prophylaxis during extracorporeal membrane oxygenation in Japan: a national survey
In conclusion, our survey revealed 39% of hospitals administered antimicrobial prophylaxis during ECMO in Japan. First-generation cephalosporins were the agents most commonly used. (Source: Journal of Artificial Organs)
Source: Journal of Artificial Organs - June 1, 2022 Category: Transplant Surgery Source Type: research

Surgical revision of failed MitraClip procedure for atrial functional mitral regurgitation
AbstractThe MitraClip system is used for patients with severe mitral regurgitation (MR) who are at high risk for open surgery. However, some patients need surgical revision for various complications. The acute outcome of MitraClip treatment for atrial functional MR (aFMR) is scarcely reported. Herein, we describe a rare case of an 80-year-old woman treated with a MitraClip for aFMR with mitral annular dilatation and failed leaflet adaptation. The patient suffered from single leaflet device attachment (SLDA) and posterior leaflet injury 3 days posttreatment. The patient successfully underwent mitral valve replacement. The p...
Source: Journal of Artificial Organs - May 27, 2022 Category: Transplant Surgery Source Type: research

Aortic root thrombosis leading to STEMI in a Heartmate 3 patient
AbstractDespite left ventricular assist device (LVAD) therapy becoming established for end-stage heart failure (HF), complications remain. Thromboembolic complications are rare with the newest iteration of LVADs. We managed a case of a continuous-flow LVAD-related thromboembolic event that presented as an acute myocardial infarction. A 64-year-old male who underwent Heartmate III® LVAD implantation had crushing substernal chest pain and ventricular tachycardia with acute anterolateral myocardial infarction on electrocardiogram on post-operative day 9. Echocardiography showed closed aortic valve and mild aortic regurgitati...
Source: Journal of Artificial Organs - May 23, 2022 Category: Transplant Surgery Source Type: research

Prediction of postoperative atrial fibrillation with the systemic immune-inflammation index in patients undergoing cardiac surgery using cardiopulmonary bypass: a retrospective, single-center study
AbstractThe systemic immune-inflammation index (SII, platelet count  × neutrophil–lymphocyte ratio) is a novel parameter for systemic inflammation. Cardiopulmonary bypass (CPB) is associated with systemic inflammatory responses. This retrospective study aimed to determine whether SII could predict postoperative atrial fibrillation (POAF) after cardiac surgery using CPB. Patients who underwent cardiac surgery using CPB between January 2020 and July 2021 were included. The primary outcome was POAF incidence within 7 days. Receiver-operating characteristic (ROC) curve analysis was used to evaluate SII ability in predi...
Source: Journal of Artificial Organs - May 17, 2022 Category: Transplant Surgery Source Type: research

High fidelity ECMO simulation: a reality check with reality –use of simulation in ECMO teaching program
We describe ECMO training execution and evaluate training effectiveness and perception by structured pre- and post-training questionnaires analysis. Results of our study show extremely high satisfaction rate with simulation training (4.9  ± 0.3, Lickert 5 point scale). High-fidelity simulation was perceived as very realistic and as such represents an important tool in learning immersion and experience. However, participants reported significant decline from their expectations with regard to structured approach to troubleshootin g (4.7 ± 0.5 vs 4.3 ± 0.7,p = 0.02) and efficiency improvement (4.7 ± 0....
Source: Journal of Artificial Organs - May 16, 2022 Category: Transplant Surgery Source Type: research

Increased risk of purge system malfunction after Impella 5.0 replacement: a case series
In conclusion, it is important to construct a treatment strategy considering the duration of use, because the risk of purge system m alfunction is high after replaced Impella 5.0. (Source: Journal of Artificial Organs)
Source: Journal of Artificial Organs - May 16, 2022 Category: Transplant Surgery Source Type: research

Establishment of a keratinocyte and fibroblast bank for clinical applications in Japan
In this study, we selected ten patients from the Department of Plastic Surgery of Kyoto University Hospital to become cell donors. We performed medical interviews and blood sampling for the donor to ensure virus safety. We examined the tissues and isolated cells by performing a nucleic acid test (NAT). To establish a master cell bank, quality evaluation was performed according to the International Conference of Harmonization (ICH) Q5A. Serological tests of the blood samples from the ten donors showed that two of them were ineligible. The cells registered in the cell bank were found to be compatible after virus testing was ...
Source: Journal of Artificial Organs - May 5, 2022 Category: Transplant Surgery Source Type: research

Unidirectional porous beta-tricalcium phosphate as a potential bone regeneration material for infectious bony cavity without debridement in pyogenic spondylitis
AbstractAn 81-year-old man was initially diagnosed with T11 osteoporotic vertebral fracture. The fractured vertebral body was filled with unidirectional porous beta-tricalcium phosphate ( β-TCP) granules, and posterior spinal fixation was conducted using percutaneous pedicle screws. However, the pain did not improve, the inflammatory response increased, and bone destructive changes extended to T10. The correct diagnosis was pyogenic spondylitis with concomitant T11 fragility vertebr al fracture. Revision surgery was conducted 2 weeks after the initial surgery, the T10 and T11 pedicle screws were removed, and refixation w...
Source: Journal of Artificial Organs - May 3, 2022 Category: Transplant Surgery Source Type: research

Does a small-diameter rod-type tunneler reduce postoperative swelling? An evaluation using a canine arteriovenous graft model
ConclusionsThe reduced-diameter rod-type tunneler may be a useful device for vascular graft implantation. (Source: Journal of Artificial Organs)
Source: Journal of Artificial Organs - April 28, 2022 Category: Transplant Surgery Source Type: research