On the total albumin losses during haemocatharsis
AbstractExcessive albumin losses during HC (haemocatharsis) are considered a potential cause of hypoalbuminemia —a key risk factor for mortality. This review on total albumin losses considers albumin “leaking” into the dialysate and losses due to protein/membrane interactions (i.e. adsorption, “secondary membrane formation” and denaturation). The former are fairly easy to determine, usually varying at the level of ~ 2 g to ~ 7 g albumin loss per session. Such values, commonly accepted as representative of the total albumin losses, are often quoted as limits/standards of permissible albumin loss per session....
Source: Journal of Artificial Organs - January 18, 2024 Category: Transplant Surgery Source Type: research
Rigid fixation of pelvic tracker essential for accurate cup placement in CT-based navigation total hip arthroplasty
AbstractResearch is lacking on the effect of intraoperative pelvic tracker displacement relative to the pelvis on cup orientation accuracy in computed tomography (CT)-based navigation (CTN) or multivariable analysis to detect factors associated with CTN accuracy. Here, we asked: (1) how pelvic tracker displacement influences the CTN accuracy of cup orientation in total hip arthroplasty (THA)? and (2) what factors are associated with CTN accuracy on multivariable analysis? Regarding cup orientation in 446 THA procedures using CTN, we evaluated clinical error defined as the difference between postoperative measurement and pr...
Source: Journal of Artificial Organs - January 10, 2024 Category: Transplant Surgery Source Type: research
Characteristics of macrophage aggregates prepared by rotation culture and their response to polymeric materials
In this study, the interaction of THP-1 cell-differentiated macrophages with biomaterials was analyzed based on a new method of seeding THP-1 cells. THP-1 cells were cultured in static and rotation culture without and with PMA. In undifferentiated THP-1 cells, there was no change in cellular function between static and rotation cultures. In rotation culture with PMA, THP-1 cells differentiated and formed macrophage aggregates. IL-1 β and MRC1 expression in macrophage aggregates was examined after differentiation and M1/M2 polarization. Macrophage aggregates in rotation culture tended to be polarized toward M2 macrophages ...
Source: Journal of Artificial Organs - January 9, 2024 Category: Transplant Surgery Source Type: research
The outcomes of a standardized protocol for extracorporeal mechanical circulatory support selection-left ventricular challenge protocol
AbstractThere are no criteria for surgical mechanical circulatory system (MCS) selection for acute heart failure. Since 2021, we have utilized cardiopulmonary bypass system to assess patients ’ heart and lung condition to inform surgical MCS selection. we aimed to retrospectively analyze the outcomes of treatments administered using our protocol. We analyzed the data of 19 patients who underwent surgical MCS implantation. We compared patients’ characteristics across the biventricular -assist device (BiVAD), central Y-Y extracorporeal membrane oxygenation (ECMO), central ECMO, and left VAD (LVAD) systems. Patients' diag...
Source: Journal of Artificial Organs - January 8, 2024 Category: Transplant Surgery Source Type: research
Mechanical support for bridge to transplant in an infant with post-cardiotomy end-stage heart failure and complete heart block: report of a case
AbstractThe patient was diagnosed with perimembranous ventricular septal defect (VSD). She underwent VSD closure and muscle bundle resection across right ventricular outflow tract at the age of 3 months. Since then, she had suffered from severe heart failure and complete heart block. Permanent pacemaker generator was implanted in the left hypochondrium. She was depended on continuous catecholamine administration, so transferred to our hospital for further management. On arrival, her body weight was 5686 g (− 2.7 SD). She underwent Excor pediatric left ventricular assist device implantation at the age of 9 months. Bec...
Source: Journal of Artificial Organs - December 29, 2023 Category: Transplant Surgery Source Type: research
Spiral groove bearing design for improving plasma skimming in rotary blood pumps
This study is the first to propose and apply a shape design strategy to generate excellent plasma skimming within an SGB. This study may contribute to the prevention of SGB hemolysis inside SGB for use in RBPs. (Source: Journal of Artificial Organs)
Source: Journal of Artificial Organs - December 28, 2023 Category: Transplant Surgery Source Type: research
Body fluid volume calculated using the uric acid kinetic model relates to the vascular event
ConclusionsExtracellular volume calculated using the uric acid kinetic model method is a prognostic factor for vascular events in patients undergoing hemodialysis. (Source: Journal of Artificial Organs)
Source: Journal of Artificial Organs - December 11, 2023 Category: Transplant Surgery Source Type: research
Removal characteristics of presepsin by operating conditions and hemofilter
AbstractPresepsin, which is used as a biomarker for sepsis, is thought to be removed by dialysis, but the actual removal properties of dialysis are unknown. We investigated the presepsin removal properties of continuous hemodiafiltration using the high concentration of presepsin from human plasma drained by plasma exchange. Each solution in plasma exchange was connected to a continuous hemodiafiltration blood circuit and circulated at 4 conditions. The results show that presepsin was confirmed to be removed more efficiently in hemofiltration than in hemodialysis. In addition, when using a polymethylmethacrylate hemofilter ...
Source: Journal of Artificial Organs - December 5, 2023 Category: Transplant Surgery Source Type: research
