Glial cells are affected more than interneurons by the loss of Engrailed 2 gene in the mouse cerebellum
J Anat. 2023 Nov 27. doi: 10.1111/joa.13982. Online ahead of print.ABSTRACTGlial cells play a pivotal role in the inflammatory processes, which are common features of several neurodevelopmental and neurodegenerative disorders. Their major role in modulating neuroinflammation underscores their significance in these conditions. Engrailed-2 knockout mice (En2-/- ) are considered a valuable model for autism spectrum disorder (ASD) due to their distinctive neuroanatomical and behavioral traits. Given the higher prevalence of ASD in males, our objective was to investigate glial and interneuron alterations in the cerebellum of En...
Source: Journal of Anatomy - November 27, 2023 Category: Anatomy Authors: Giulia Lazzarini Alessandra Gatta Vincenzo Miragliotta Francesca Vaglini Cristina Viaggi Andrea Pirone Source Type: research

Whole-brain mapping of monosynaptic afferent inputs to the CRH neurons in the medial prefrontal cortex of mice
J Anat. 2023 Nov 27. doi: 10.1111/joa.13981. Online ahead of print.ABSTRACTCorticotropin-releasing hormone (CRH) neurons are densely distributed in the medial prefrontal cortex (mPFC), which plays a crucial role in integrating and processing emotional and cognitive inputs from other brain regions. Therefore, it is important to know the neural afferent patterns of mPFCCRH neurons, which are still unclear. Here, we utilized a rabies virus-based monosynaptic retrograde tracing system to map the presynaptic afferents of the mPFCCRH neurons throughout the entire brain. The results show that the mPFCCRH neurons receive inputs fr...
Source: Journal of Anatomy - November 27, 2023 Category: Anatomy Authors: Xiao-Lan Li Fei Li Xin-Yi Zhu Xiao-Dong Wang Zhen-Zhen Kou Shang-Qing Liu Hui Li Source Type: research

Glial cells are affected more than interneurons by the loss of Engrailed 2 gene in the mouse cerebellum
J Anat. 2023 Nov 27. doi: 10.1111/joa.13982. Online ahead of print.ABSTRACTGlial cells play a pivotal role in the inflammatory processes, which are common features of several neurodevelopmental and neurodegenerative disorders. Their major role in modulating neuroinflammation underscores their significance in these conditions. Engrailed-2 knockout mice (En2-/- ) are considered a valuable model for autism spectrum disorder (ASD) due to their distinctive neuroanatomical and behavioral traits. Given the higher prevalence of ASD in males, our objective was to investigate glial and interneuron alterations in the cerebellum of En...
Source: Journal of Anatomy - November 27, 2023 Category: Anatomy Authors: Giulia Lazzarini Alessandra Gatta Vincenzo Miragliotta Francesca Vaglini Cristina Viaggi Andrea Pirone Source Type: research

Corona mortis and pelvic dissection: Understanding the relationship between anatomical structures and bone areas
J Anat. 2023 Nov 22. doi: 10.1111/joa.13978. Online ahead of print.ABSTRACTPelvic fractures are becoming increasingly frequent. The gold standard for surgical managements remains open procedures. Despite its excellent biomechanically results, it can lead to many complications. Minimally invasive surgery could reduce these complications. For complex pelvic trauma, extraperitoneal endoscopic technique has never been described. The aim of this study is to determine anatomical landmarks which are useful for endoscopic pelvic ring surgery using an extraperitoneal approach. The second objective is to compare this minimally invas...
Source: Journal of Anatomy - November 22, 2023 Category: Anatomy Authors: Guillaume David Nathan Milliot Louis Rony Henri-Dominique Fournier Xavier Demondion Florian Bernard Source Type: research

Reinterpretation of tuberculate cervical vertebrae of Eocene birds as an exceptional anti-predator adaptation against the mammalian craniocervical killing bite
We report avian cervical vertebrae from the Quercy fissure fillings in France, which are densely covered with villi-like tubercles. Two of these vertebrae stem from a late Eocene site, another lacks exact stratigraphic data. Similar cervical vertebrae occur in avian species from Eocene fossils sites in Germany and the United Kingdom, but the new fossils are the only three-dimensionally preserved vertebrae with pronounced surface sculpturing. So far, the evolutionary significance of this highly bizarre morphology, which is unknown from extant birds, remained elusive, and even a pathological origin was considered. We note th...
Source: Journal of Anatomy - November 22, 2023 Category: Anatomy Authors: Gerald Mayr Ursula B G öhlich Zbyn ěk Roček Alfred Lemierre Viola Winkler Georgios L Georgalis Source Type: research

Corona mortis and pelvic dissection: Understanding the relationship between anatomical structures and bone areas
J Anat. 2023 Nov 22. doi: 10.1111/joa.13978. Online ahead of print.ABSTRACTPelvic fractures are becoming increasingly frequent. The gold standard for surgical managements remains open procedures. Despite its excellent biomechanically results, it can lead to many complications. Minimally invasive surgery could reduce these complications. For complex pelvic trauma, extraperitoneal endoscopic technique has never been described. The aim of this study is to determine anatomical landmarks which are useful for endoscopic pelvic ring surgery using an extraperitoneal approach. The second objective is to compare this minimally invas...
Source: Journal of Anatomy - November 22, 2023 Category: Anatomy Authors: Guillaume David Nathan Milliot Louis Rony Henri-Dominique Fournier Xavier Demondion Florian Bernard Source Type: research

Reinterpretation of tuberculate cervical vertebrae of Eocene birds as an exceptional anti-predator adaptation against the mammalian craniocervical killing bite
We report avian cervical vertebrae from the Quercy fissure fillings in France, which are densely covered with villi-like tubercles. Two of these vertebrae stem from a late Eocene site, another lacks exact stratigraphic data. Similar cervical vertebrae occur in avian species from Eocene fossils sites in Germany and the United Kingdom, but the new fossils are the only three-dimensionally preserved vertebrae with pronounced surface sculpturing. So far, the evolutionary significance of this highly bizarre morphology, which is unknown from extant birds, remained elusive, and even a pathological origin was considered. We note th...
Source: Journal of Anatomy - November 22, 2023 Category: Anatomy Authors: Gerald Mayr Ursula B G öhlich Zbyn ěk Roček Alfred Lemierre Viola Winkler Georgios L Georgalis Source Type: research

Corona mortis and pelvic dissection: Understanding the relationship between anatomical structures and bone areas
J Anat. 2023 Nov 22. doi: 10.1111/joa.13978. Online ahead of print.ABSTRACTPelvic fractures are becoming increasingly frequent. The gold standard for surgical managements remains open procedures. Despite its excellent biomechanically results, it can lead to many complications. Minimally invasive surgery could reduce these complications. For complex pelvic trauma, extraperitoneal endoscopic technique has never been described. The aim of this study is to determine anatomical landmarks which are useful for endoscopic pelvic ring surgery using an extraperitoneal approach. The second objective is to compare this minimally invas...
Source: Journal of Anatomy - November 22, 2023 Category: Anatomy Authors: Guillaume David Nathan Milliot Louis Rony Henri-Dominique Fournier Xavier Demondion Florian Bernard Source Type: research

Reinterpretation of tuberculate cervical vertebrae of Eocene birds as an exceptional anti-predator adaptation against the mammalian craniocervical killing bite
We report avian cervical vertebrae from the Quercy fissure fillings in France, which are densely covered with villi-like tubercles. Two of these vertebrae stem from a late Eocene site, another lacks exact stratigraphic data. Similar cervical vertebrae occur in avian species from Eocene fossils sites in Germany and the United Kingdom, but the new fossils are the only three-dimensionally preserved vertebrae with pronounced surface sculpturing. So far, the evolutionary significance of this highly bizarre morphology, which is unknown from extant birds, remained elusive, and even a pathological origin was considered. We note th...
Source: Journal of Anatomy - November 22, 2023 Category: Anatomy Authors: Gerald Mayr Ursula B G öhlich Zbyn ěk Roček Alfred Lemierre Viola Winkler Georgios L Georgalis Source Type: research

Corona mortis and pelvic dissection: Understanding the relationship between anatomical structures and bone areas
J Anat. 2023 Nov 22. doi: 10.1111/joa.13978. Online ahead of print.ABSTRACTPelvic fractures are becoming increasingly frequent. The gold standard for surgical managements remains open procedures. Despite its excellent biomechanically results, it can lead to many complications. Minimally invasive surgery could reduce these complications. For complex pelvic trauma, extraperitoneal endoscopic technique has never been described. The aim of this study is to determine anatomical landmarks which are useful for endoscopic pelvic ring surgery using an extraperitoneal approach. The second objective is to compare this minimally invas...
Source: Journal of Anatomy - November 22, 2023 Category: Anatomy Authors: Guillaume David Nathan Milliot Louis Rony Henri-Dominique Fournier Xavier Demondion Florian Bernard Source Type: research

Reinterpretation of tuberculate cervical vertebrae of Eocene birds as an exceptional anti-predator adaptation against the mammalian craniocervical killing bite
We report avian cervical vertebrae from the Quercy fissure fillings in France, which are densely covered with villi-like tubercles. Two of these vertebrae stem from a late Eocene site, another lacks exact stratigraphic data. Similar cervical vertebrae occur in avian species from Eocene fossils sites in Germany and the United Kingdom, but the new fossils are the only three-dimensionally preserved vertebrae with pronounced surface sculpturing. So far, the evolutionary significance of this highly bizarre morphology, which is unknown from extant birds, remained elusive, and even a pathological origin was considered. We note th...
Source: Journal of Anatomy - November 22, 2023 Category: Anatomy Authors: Gerald Mayr Ursula B G öhlich Zbyn ěk Roček Alfred Lemierre Viola Winkler Georgios L Georgalis Source Type: research

Corona mortis and pelvic dissection: Understanding the relationship between anatomical structures and bone areas
J Anat. 2023 Nov 22. doi: 10.1111/joa.13978. Online ahead of print.ABSTRACTPelvic fractures are becoming increasingly frequent. The gold standard for surgical managements remains open procedures. Despite its excellent biomechanically results, it can lead to many complications. Minimally invasive surgery could reduce these complications. For complex pelvic trauma, extraperitoneal endoscopic technique has never been described. The aim of this study is to determine anatomical landmarks which are useful for endoscopic pelvic ring surgery using an extraperitoneal approach. The second objective is to compare this minimally invas...
Source: Journal of Anatomy - November 22, 2023 Category: Anatomy Authors: Guillaume David Nathan Milliot Louis Rony Henri-Dominique Fournier Xavier Demondion Florian Bernard Source Type: research

Reinterpretation of tuberculate cervical vertebrae of Eocene birds as an exceptional anti-predator adaptation against the mammalian craniocervical killing bite
We report avian cervical vertebrae from the Quercy fissure fillings in France, which are densely covered with villi-like tubercles. Two of these vertebrae stem from a late Eocene site, another lacks exact stratigraphic data. Similar cervical vertebrae occur in avian species from Eocene fossils sites in Germany and the United Kingdom, but the new fossils are the only three-dimensionally preserved vertebrae with pronounced surface sculpturing. So far, the evolutionary significance of this highly bizarre morphology, which is unknown from extant birds, remained elusive, and even a pathological origin was considered. We note th...
Source: Journal of Anatomy - November 22, 2023 Category: Anatomy Authors: Gerald Mayr Ursula B G öhlich Zbyn ěk Roček Alfred Lemierre Viola Winkler Georgios L Georgalis Source Type: research

Sphenomandibular ligament and degenerating Meckel's cartilage revisited: Sequential variations with temporal bone deformity for ligament attachment in near-term human fetuses
CONCLUSIONS: Most of the specimens (n = 15) exhibited a sequential change from a cartilaginous SML as a continuation of the MC remnant to the ligament after the disappearance of the cartilage. The degenerating MC appeared to cause transformation from the AP-goniale complex and/or TYB to "another ligament" that replaced the usual SML at the upper part. Near the MC remnant, a similar transformation was also suggested on the squamosa or petrosa. The sphenoid spine appeared to originate often from the sphenoid ala major but sometimes from the TYB.PMID:37988318 | DOI:10.1111/joa.13974 (Source: Journal of Anatomy)
Source: Journal of Anatomy - November 21, 2023 Category: Anatomy Authors: Zhe-Wu Jin Yohei Honkura Masahito Yamamoto Shogo Hayashi Gen Murakami Hiroshi Abe Jos é Francisco Rodríguez-Vázquez Source Type: research

Axillary arch (of Langer): A large-scale dissection and simulation study based on unembalmed cadavers of body donors
J Anat. 2023 Nov 15. doi: 10.1111/joa.13976. Online ahead of print.ABSTRACTConnective or muscular tissue crossing the axilla is named axillary arch (of Langer). It is known to complicate axillary surgery and to compress nerves and vessels transiting from the axilla to the arm. Our study aims at systematically researching the frequency, insertions, tissue composition and dimension of axillary arches in a large cohort of individuals with regard to gender and bilaterality. In addition, it aims at evaluating the ability of axillary arches to cause compression of the axillary neurovascular bundle. Four hundred axillae from 200 ...
Source: Journal of Anatomy - November 15, 2023 Category: Anatomy Authors: Jeremias T Weninger Paata Pruidze Giorgi Didava Tobias Rossmann Stefan H Geyer Stefan Meng Wolfgang J Weninger Source Type: research