Morphological variation, modularity and integration in the scapula and humerus of Lissotriton newts
J Anat. 2024 Mar 2. doi: 10.1111/joa.14030. Online ahead of print.ABSTRACTThe modular organization of tetrapod paired limbs and girdles, influenced by the expression of Hox genes is one of the primary driving forces of the evolution of animal locomotion. The increased morphological diversification of the paired limbs is correlated with reduced between-limb covariation, while correlation within the elements is usually higher than between the elements. The tailed amphibians, such as Lissotriton newts, have a biphasic lifestyle with aquatic and terrestrial environments imposing different constraints on limb skeleton. By emplo...
Source: Journal of Anatomy - March 2, 2024 Category: Anatomy Authors: Aleksandar Uro šević Sanja Bude čević Katarina Ljubisavljevi ć Nata ša Tomašević Kolarov Maja Ajdukovi ć Source Type: research

Size and shape heterodonty in the early Permian synapsid Mesenosaurus efremovi
J Anat. 2024 Mar 2. doi: 10.1111/joa.14034. Online ahead of print.ABSTRACTPaleozoic synapsids represent the first chapter in the evolution of this large clade that includes mammals. These fascinating terrestrial vertebrates were the first amniotes to successfully adapt to a wide range of feeding strategies, reflected by their varied dental morphologies. Evolution of the marginal dentition on the mammalian side of amniotes is characterized by strong, size and shape heterodonty, with the late Permian therapsids showing heterodonty with the presence of incisiform, caniniform, and multicuspid molariform dentition. Rarity of av...
Source: Journal of Anatomy - March 2, 2024 Category: Anatomy Authors: Tea Maho Sigi Maho Joseph J Bevitt Robert R Reisz Source Type: research

Morphological variation, modularity and integration in the scapula and humerus of Lissotriton newts
J Anat. 2024 Mar 2. doi: 10.1111/joa.14030. Online ahead of print.ABSTRACTThe modular organization of tetrapod paired limbs and girdles, influenced by the expression of Hox genes is one of the primary driving forces of the evolution of animal locomotion. The increased morphological diversification of the paired limbs is correlated with reduced between-limb covariation, while correlation within the elements is usually higher than between the elements. The tailed amphibians, such as Lissotriton newts, have a biphasic lifestyle with aquatic and terrestrial environments imposing different constraints on limb skeleton. By emplo...
Source: Journal of Anatomy - March 2, 2024 Category: Anatomy Authors: Aleksandar Uro šević Sanja Bude čević Katarina Ljubisavljevi ć Nata ša Tomašević Kolarov Maja Ajdukovi ć Source Type: research

Size and shape heterodonty in the early Permian synapsid Mesenosaurus efremovi
J Anat. 2024 Mar 2. doi: 10.1111/joa.14034. Online ahead of print.ABSTRACTPaleozoic synapsids represent the first chapter in the evolution of this large clade that includes mammals. These fascinating terrestrial vertebrates were the first amniotes to successfully adapt to a wide range of feeding strategies, reflected by their varied dental morphologies. Evolution of the marginal dentition on the mammalian side of amniotes is characterized by strong, size and shape heterodonty, with the late Permian therapsids showing heterodonty with the presence of incisiform, caniniform, and multicuspid molariform dentition. Rarity of av...
Source: Journal of Anatomy - March 2, 2024 Category: Anatomy Authors: Tea Maho Sigi Maho Joseph J Bevitt Robert R Reisz Source Type: research

Morphological variation, modularity and integration in the scapula and humerus of Lissotriton newts
J Anat. 2024 Mar 2. doi: 10.1111/joa.14030. Online ahead of print.ABSTRACTThe modular organization of tetrapod paired limbs and girdles, influenced by the expression of Hox genes is one of the primary driving forces of the evolution of animal locomotion. The increased morphological diversification of the paired limbs is correlated with reduced between-limb covariation, while correlation within the elements is usually higher than between the elements. The tailed amphibians, such as Lissotriton newts, have a biphasic lifestyle with aquatic and terrestrial environments imposing different constraints on limb skeleton. By emplo...
Source: Journal of Anatomy - March 2, 2024 Category: Anatomy Authors: Aleksandar Uro šević Sanja Bude čević Katarina Ljubisavljevi ć Nata ša Tomašević Kolarov Maja Ajdukovi ć Source Type: research

Size and shape heterodonty in the early Permian synapsid Mesenosaurus efremovi
J Anat. 2024 Mar 2. doi: 10.1111/joa.14034. Online ahead of print.ABSTRACTPaleozoic synapsids represent the first chapter in the evolution of this large clade that includes mammals. These fascinating terrestrial vertebrates were the first amniotes to successfully adapt to a wide range of feeding strategies, reflected by their varied dental morphologies. Evolution of the marginal dentition on the mammalian side of amniotes is characterized by strong, size and shape heterodonty, with the late Permian therapsids showing heterodonty with the presence of incisiform, caniniform, and multicuspid molariform dentition. Rarity of av...
Source: Journal of Anatomy - March 2, 2024 Category: Anatomy Authors: Tea Maho Sigi Maho Joseph J Bevitt Robert R Reisz Source Type: research

Morphological variation, modularity and integration in the scapula and humerus of Lissotriton newts
J Anat. 2024 Mar 2. doi: 10.1111/joa.14030. Online ahead of print.ABSTRACTThe modular organization of tetrapod paired limbs and girdles, influenced by the expression of Hox genes is one of the primary driving forces of the evolution of animal locomotion. The increased morphological diversification of the paired limbs is correlated with reduced between-limb covariation, while correlation within the elements is usually higher than between the elements. The tailed amphibians, such as Lissotriton newts, have a biphasic lifestyle with aquatic and terrestrial environments imposing different constraints on limb skeleton. By emplo...
Source: Journal of Anatomy - March 2, 2024 Category: Anatomy Authors: Aleksandar Uro šević Sanja Bude čević Katarina Ljubisavljevi ć Nata ša Tomašević Kolarov Maja Ajdukovi ć Source Type: research

Size and shape heterodonty in the early Permian synapsid Mesenosaurus efremovi
J Anat. 2024 Mar 2. doi: 10.1111/joa.14034. Online ahead of print.ABSTRACTPaleozoic synapsids represent the first chapter in the evolution of this large clade that includes mammals. These fascinating terrestrial vertebrates were the first amniotes to successfully adapt to a wide range of feeding strategies, reflected by their varied dental morphologies. Evolution of the marginal dentition on the mammalian side of amniotes is characterized by strong, size and shape heterodonty, with the late Permian therapsids showing heterodonty with the presence of incisiform, caniniform, and multicuspid molariform dentition. Rarity of av...
Source: Journal of Anatomy - March 2, 2024 Category: Anatomy Authors: Tea Maho Sigi Maho Joseph J Bevitt Robert R Reisz Source Type: research

Effect of deletion of the protein kinase PRKD1 on development of the mouse embryonic heart
J Anat. 2024 Feb 28. doi: 10.1111/joa.14033. Online ahead of print.ABSTRACTCongenital heart disease (CHD) is the most common congenital anomaly, with an overall incidence of approximately 1% in the United Kingdom. Exome sequencing in large CHD cohorts has been performed to provide insights into the genetic aetiology of CHD. This includes a study of 1891 probands by our group in collaboration with others, which identified three novel genes-CDK13, PRKD1, and CHD4, in patients with syndromic CHD. PRKD1 encodes a serine/threonine protein kinase, which is important in a variety of fundamental cellular functions. Individuals wit...
Source: Journal of Anatomy - February 29, 2024 Category: Anatomy Authors: Qazi Waheed-Ullah Anna Wilsdon Aseel Abbad Sophie Rochette Frances Bu'Lock Marc-Phillip Hitz Gregor Dombrowsky Friederike Cuello J David Brook Siobhan Loughna Source Type: research

What is new in flexor tendon pulleys and the gaps between them in triphalangeal fingers of the hand?
CONCLUSIONS: The flexor pulleys in the triphalangeal fingers of the hand have shown enormous variability in arrangement and shape, and also rarely appear all in the same finger. This peculiar anatomical arrangement can help the different professionals who perform their clinical work in this region.PMID:38419199 | DOI:10.1111/joa.14031 (Source: Journal of Anatomy)
Source: Journal of Anatomy - February 29, 2024 Category: Anatomy Authors: Julio De Las Heras Clara Sim ón de Blas Guillermo Jos é Salaberri Ioannis Krompas Lukasz Olewnik Sara Quinones Marc Garc ía-Elías Jos é Ramón Sanudo Paloma Aragon és Source Type: research

Effect of deletion of the protein kinase PRKD1 on development of the mouse embryonic heart
J Anat. 2024 Feb 28. doi: 10.1111/joa.14033. Online ahead of print.ABSTRACTCongenital heart disease (CHD) is the most common congenital anomaly, with an overall incidence of approximately 1% in the United Kingdom. Exome sequencing in large CHD cohorts has been performed to provide insights into the genetic aetiology of CHD. This includes a study of 1891 probands by our group in collaboration with others, which identified three novel genes-CDK13, PRKD1, and CHD4, in patients with syndromic CHD. PRKD1 encodes a serine/threonine protein kinase, which is important in a variety of fundamental cellular functions. Individuals wit...
Source: Journal of Anatomy - February 29, 2024 Category: Anatomy Authors: Qazi Waheed-Ullah Anna Wilsdon Aseel Abbad Sophie Rochette Frances Bu'Lock Marc-Phillip Hitz Gregor Dombrowsky Friederike Cuello J David Brook Siobhan Loughna Source Type: research

What is new in flexor tendon pulleys and the gaps between them in triphalangeal fingers of the hand?
CONCLUSIONS: The flexor pulleys in the triphalangeal fingers of the hand have shown enormous variability in arrangement and shape, and also rarely appear all in the same finger. This peculiar anatomical arrangement can help the different professionals who perform their clinical work in this region.PMID:38419199 | DOI:10.1111/joa.14031 (Source: Journal of Anatomy)
Source: Journal of Anatomy - February 29, 2024 Category: Anatomy Authors: Julio De Las Heras Clara Sim ón de Blas Guillermo Jos é Salaberri Ioannis Krompas Lukasz Olewnik Sara Quinones Marc Garc ía-Elías Jos é Ramón Sanudo Paloma Aragon és Source Type: research

Effect of deletion of the protein kinase PRKD1 on development of the mouse embryonic heart
J Anat. 2024 Feb 28. doi: 10.1111/joa.14033. Online ahead of print.ABSTRACTCongenital heart disease (CHD) is the most common congenital anomaly, with an overall incidence of approximately 1% in the United Kingdom. Exome sequencing in large CHD cohorts has been performed to provide insights into the genetic aetiology of CHD. This includes a study of 1891 probands by our group in collaboration with others, which identified three novel genes-CDK13, PRKD1, and CHD4, in patients with syndromic CHD. PRKD1 encodes a serine/threonine protein kinase, which is important in a variety of fundamental cellular functions. Individuals wit...
Source: Journal of Anatomy - February 29, 2024 Category: Anatomy Authors: Qazi Waheed-Ullah Anna Wilsdon Aseel Abbad Sophie Rochette Frances Bu'Lock Marc-Phillip Hitz Gregor Dombrowsky Friederike Cuello J David Brook Siobhan Loughna Source Type: research

What is new in flexor tendon pulleys and the gaps between them in triphalangeal fingers of the hand?
CONCLUSIONS: The flexor pulleys in the triphalangeal fingers of the hand have shown enormous variability in arrangement and shape, and also rarely appear all in the same finger. This peculiar anatomical arrangement can help the different professionals who perform their clinical work in this region.PMID:38419199 | DOI:10.1111/joa.14031 (Source: Journal of Anatomy)
Source: Journal of Anatomy - February 29, 2024 Category: Anatomy Authors: Julio De Las Heras Clara Sim ón de Blas Guillermo Jos é Salaberri Ioannis Krompas Lukasz Olewnik Sara Quinones Marc Garc ía-Elías Jos é Ramón Sanudo Paloma Aragon és Source Type: research

Brain volume in infants with metopic synostosis: Less white matter volume with an accelerated growth pattern in early life
J Anat. 2024 Feb 28. doi: 10.1111/joa.14028. Online ahead of print.ABSTRACTMetopic synostosis patients are at risk for neurodevelopmental disorders despite a negligible risk of intracranial hypertension. To gain insight into the underlying pathophysiology of metopic synostosis and associated neurodevelopmental disorders, we aimed to investigate brain volumes of non-syndromic metopic synostosis patients using preoperative MRI brain scans. MRI brain scans were processed with HyperDenseNet to calculate total intracranial volume (TIV), total brain volume (TBV), total grey matter volume (TGMV), total white matter volume (TWMV) ...
Source: Journal of Anatomy - February 28, 2024 Category: Anatomy Authors: L Gaillard M C Tjaberinga M H G Dremmen I M J Mathijssen H A Vrooman Source Type: research