Deciphering induced variability, character association and multivariate analysis utilizing gamma rays and ethyl methanesulfonate in bread wheat ( < em > Triticum aestivum < /em > L.) genotypes with differential grain texture
CONCLUSIONS: Assessment of mutagen sensitivity showed that semi-hard wheat varieties were responsive to both mutagens, particularly EMS and generated higher variability and divergence than the soft textured varieties. Hence, gamma rays were proved to be more effective in generating higher variability than ethyl methanesulfonate. A total of 117 putative mutants were identified with desirable agro-morphological attributes. Among these, mutants with higher inter-cluster distance can be used as parents in hybridization programs and serve as important genetic resources in future wheat improvement programs.PMID:38319050 | DOI:10...
Source: International Journal of Radiation Biology - February 6, 2024 Category: Radiology Authors: Amit Rana Vijay Rana Suman Bakshi Vinod Kumar Sood None Priyanka None Anuradha Source Type: research

Modifications of DAMPs levels in extracellular environment induced by aminolevulinic acid-based photodynamic therapy of esophageal cancer cells
CONCLUSION: Aminolevulinic acid-based photodynamic therapy leads to alterations in local extracellular levels of damage associated molecular patterns, however, comprehensive studies are needed to find whether they can be responsible for macrophage phenotype modifications.PMID:38319688 | DOI:10.1080/09553002.2024.2310002 (Source: International Journal of Radiation Biology)
Source: International Journal of Radiation Biology - February 6, 2024 Category: Radiology Authors: Beata Čunderlíková Krist ína Klučková Pavel Bab ál Peter Mlkv ý Tibor Teplick ý Source Type: research

Intergenerational effects of ionizing radiation: review of recent studies from human data (2018-2021)
CONCLUSION: This review, covering the period 2018-2022, serves as an extension of the previous systematic review conducted by Stephens et al. (2024), which encompassed the years 1988-2018. Together, these two papers offer a comprehensive overview of the available evidence regarding the intergenerational effects of parental pre-conceptional exposure to ionizing radiation. Overall, the findings do not provide strong evidence supporting a significant association between adverse (or other) outcomes in unexposed children and parental preconception radiation exposure.PMID:38319708 | DOI:10.1080/09553002.2024.2309917 (Source: Int...
Source: International Journal of Radiation Biology - February 6, 2024 Category: Radiology Authors: A Amrenova C Baudin E Ostroumova J Stephens R Anderson D Laurier Source Type: research

High variability in short and long-term recovery kinetic of blood cell count and blood chemistry in a partial body irradiation mouse model
CONCLUSIONS: Irradiated animals had significant depletion of white blood cells, red blood cells and platelets up to 10 days post-irradiation. Separation between PBI and WBI were observed at 10- and 20-days post-irradiation at which point PBI animals showed sign of recovery while overall cell count remains depleted in WBI animals up to 30 days post-irradiation. In addition, significant changes were found in parameters indicative of hematopoietic injury including hemoglobin count, hematocrit count and white blood cell population. Significant changes were observed in kidney function with changes to blood urea nitrogen and cal...
Source: International Journal of Radiation Biology - February 2, 2024 Category: Radiology Authors: Tien T Tang Janice A Zawaski Omaima M Sabek M Waleed Gaber Source Type: research

Alleviation of radiation combined skin injury in rat model by topical application of ascorbate formulation
CONCLUSION: Topical application of the ascorbate formulation in RCI resulted in a significant improvement in delayed wound healing, leading to accelerated wound closure by mitigating the expression of inflammatory responses.PMID:38306495 | DOI:10.1080/09553002.2024.2310016 (Source: International Journal of Radiation Biology)
Source: International Journal of Radiation Biology - February 2, 2024 Category: Radiology Authors: Ajay Kumar Sharma Aman Kalonia Rishav Kumar None Kirti Priyanka Shaw M H Yashvarddhan Arpana Vibhuti Sandeep Kumar Shukla Source Type: research

Phenotypic and transcriptional changes in lens epithelial cells following acute and fractionated ionizing radiation exposure
CONCLUSIONS: Overall, this research provides novel insights into the dose and fractionation effects on functional changes and transcriptional regulatory networks in LEC, furthering our understanding of the mechanisms behind radiation induced cataracts.PMID:38289679 | DOI:10.1080/09553002.2023.2295965 (Source: International Journal of Radiation Biology)
Source: International Journal of Radiation Biology - January 30, 2024 Category: Radiology Authors: Graysen Vigneux Taylor Laframboise Sujeenthar Tharmalingam Christopher Thome Source Type: research

The ICRP, MELODI, and ALLIANCE workshop on effects of ionizing radiation exposure in offspring and next generations: a summary of discussions
CONCLUSIONS: Based on the discussions and presentations during the breakout sessions, newer publications, and gaps on the current scientific literature were identified. For instance, there are some ongoing systematic reviews and radiation epidemiology reviews of intrauterine effects. There are newer methods of Monte Carlo simulation for fetal dosimetry, and advances in radiation genetics, epigenetics, and radiobiology studies. While the current impact of hereditary effects on the global detriment was reported as small, the questions surrounding the effects of radiation exposure on offspring and the next generation are cruc...
Source: International Journal of Radiation Biology - January 29, 2024 Category: Radiology Authors: Ämilie Degenhardt Shayenthiran Sreetharan Aidana Amrenova Christelle Adam-Guillermin Fieke Dekkers Sara Dumit Sandrine Frelon Nele Horemans Dominique Laurier Liudmila Liutsko Sisko Salomaa Thierry Schneider Manoor P Hande Richard Wakeford Kimberly E Appl Source Type: research

Molecular and physiological characterization of early semi-dwarf mutants of rice and localization of SNP variants in Sd1 locus generated through gamma radiation
CONCLUSIONS: The impact of a defective gibberellic acid-mediated signaling pathway in mutants to produce a novel high-yielding and early maturing semi-dwarf rice variety.PMID:38285971 | DOI:10.1080/09553002.2024.2304827 (Source: International Journal of Radiation Biology)
Source: International Journal of Radiation Biology - January 29, 2024 Category: Radiology Authors: Selvaraj Ramchander Andrew-Peter-Leon M T Yasin Jeshima Khan Jegadeesan Souframanien Madhavan Arumugam Pillai Source Type: research

Co < sup > 60 < /sup > gamma irradiation reduces rooting ability in M < sub > 1 < /sub > V < sub > 1 < /sub > < em > Salvia uliginosa < /em > while inducing leaf variegation
CONCLUSIONS: Root quality, survival, and plant height were reduced at higher levels of gamma radiation in the M1V1. However, rooting ability was not impacted in M1V2 selections. Additionally, one mutant was isolated from the 35 Gy treatment with variegated leaves for a mutation rate of 4%. Our research determined a treatment rate that induced a dominant mutation in S. uliginosa while minimizing the deleterious influence of gamma radiation.PMID:38265867 | DOI:10.1080/09553002.2024.2304852 (Source: International Journal of Radiation Biology)
Source: International Journal of Radiation Biology - January 24, 2024 Category: Radiology Authors: Rebekah C I Maynard John M Ruter Source Type: research

Screening radiation-differentially expressed circular RNAs and establishing dose classification models in the human lymphoblastoid cell line AHH-1
CONCLUSIONS: Ionizing radiation can indeed modulate the circRNA expression profile in the human lymphoblastoid cell line AHH-1. The differentially expressed circRNAs exhibit the potential for rapid and high-throughput dose classification.PMID:38252315 | DOI:10.1080/09553002.2024.2304850 (Source: International Journal of Radiation Biology)
Source: International Journal of Radiation Biology - January 22, 2024 Category: Radiology Authors: Xue-Lei Tian Ting-Ting Zhang Tian-Jing Cai Mei Tian Qing-Jie Liu Source Type: research