Ionizing radiation exposure effects across multiple generations: evidence and lessons from non-human biota
In this report, we summarize the evidence of multi- and trans-generational effects in non-human biota species that was discussed at the ICRP workshop entitled "Effects of Ionizing Radiation Exposure in Offspring and Next Generations" in June 2022. Epigenetic changes, including changes in DNA methylation, have been observed in trans- and multi-generational irradiation studies in both plants and animals. There were also reports of changes in offspring survival and reproduction. The reported evidence for altered reproduction is an area of potential concern, due to possible effects at the population or ecosystem level. Differe...
Source: International Journal of Radiation Biology - December 11, 2023 Category: Radiology Authors: Shayenthiran Sreetharan Sandrine Frelon Nele Horemans Patrick Laloi Sisko Salomaa Christelle Adam-Guillermin Source Type: research

Epidemiological and experimental evidence for radiation-induced health effects in the progeny after exposure in utero
CONCLUSION: There is no convincing evidence, neither from epidemiological nor experimental data of the existence of a dose threshold for developmental defects after radiation exposure in utero. This must be taken into account in the revision of rules and regulations of radiation protection in medicine.PMID:38079348 | DOI:10.1080/09553002.2023.2283088 (Source: International Journal of Radiation Biology)
Source: International Journal of Radiation Biology - December 11, 2023 Category: Radiology Authors: Mohammed Abderrafi Benotmane Klaus Ruediger Trott Source Type: research

Ionizing radiation exposure effects across multiple generations: evidence and lessons from non-human biota
In this report, we summarize the evidence of multi- and trans-generational effects in non-human biota species that was discussed at the ICRP workshop entitled "Effects of Ionizing Radiation Exposure in Offspring and Next Generations" in June 2022. Epigenetic changes, including changes in DNA methylation, have been observed in trans- and multi-generational irradiation studies in both plants and animals. There were also reports of changes in offspring survival and reproduction. The reported evidence for altered reproduction is an area of potential concern, due to possible effects at the population or ecosystem level. Differe...
Source: International Journal of Radiation Biology - December 11, 2023 Category: Radiology Authors: Shayenthiran Sreetharan Sandrine Frelon Nele Horemans Patrick Laloi Sisko Salomaa Christelle Adam-Guillermin Source Type: research

Epidemiological and experimental evidence for radiation-induced health effects in the progeny after exposure in utero
CONCLUSION: There is no convincing evidence, neither from epidemiological nor experimental data of the existence of a dose threshold for developmental defects after radiation exposure in utero. This must be taken into account in the revision of rules and regulations of radiation protection in medicine.PMID:38079348 | DOI:10.1080/09553002.2023.2283088 (Source: International Journal of Radiation Biology)
Source: International Journal of Radiation Biology - December 11, 2023 Category: Radiology Authors: Mohammed Abderrafi Benotmane Klaus Ruediger Trott Source Type: research

Ionizing radiation exposure effects across multiple generations: evidence and lessons from non-human biota
In this report, we summarize the evidence of multi- and trans-generational effects in non-human biota species that was discussed at the ICRP workshop entitled "Effects of Ionizing Radiation Exposure in Offspring and Next Generations" in June 2022. Epigenetic changes, including changes in DNA methylation, have been observed in trans- and multi-generational irradiation studies in both plants and animals. There were also reports of changes in offspring survival and reproduction. The reported evidence for altered reproduction is an area of potential concern, due to possible effects at the population or ecosystem level. Differe...
Source: International Journal of Radiation Biology - December 11, 2023 Category: Radiology Authors: Shayenthiran Sreetharan Sandrine Frelon Nele Horemans Patrick Laloi Sisko Salomaa Christelle Adam-Guillermin Source Type: research

Epidemiological and experimental evidence for radiation-induced health effects in the progeny after exposure in utero
CONCLUSION: There is no convincing evidence, neither from epidemiological nor experimental data of the existence of a dose threshold for developmental defects after radiation exposure in utero. This must be taken into account in the revision of rules and regulations of radiation protection in medicine.PMID:38079348 | DOI:10.1080/09553002.2023.2283088 (Source: International Journal of Radiation Biology)
Source: International Journal of Radiation Biology - December 11, 2023 Category: Radiology Authors: Mohammed Abderrafi Benotmane Klaus Ruediger Trott Source Type: research

Ionizing radiation exposure effects across multiple generations: evidence and lessons from non-human biota
In this report, we summarize the evidence of multi- and trans-generational effects in non-human biota species that was discussed at the ICRP workshop entitled "Effects of Ionizing Radiation Exposure in Offspring and Next Generations" in June 2022. Epigenetic changes, including changes in DNA methylation, have been observed in trans- and multi-generational irradiation studies in both plants and animals. There were also reports of changes in offspring survival and reproduction. The reported evidence for altered reproduction is an area of potential concern, due to possible effects at the population or ecosystem level. Differe...
Source: International Journal of Radiation Biology - December 11, 2023 Category: Radiology Authors: Shayenthiran Sreetharan Sandrine Frelon Nele Horemans Patrick Laloi Sisko Salomaa Christelle Adam-Guillermin Source Type: research

Epidemiological and experimental evidence for radiation-induced health effects in the progeny after exposure in utero
CONCLUSION: There is no convincing evidence, neither from epidemiological nor experimental data of the existence of a dose threshold for developmental defects after radiation exposure in utero. This must be taken into account in the revision of rules and regulations of radiation protection in medicine.PMID:38079348 | DOI:10.1080/09553002.2023.2283088 (Source: International Journal of Radiation Biology)
Source: International Journal of Radiation Biology - December 11, 2023 Category: Radiology Authors: Mohammed Abderrafi Benotmane Klaus Ruediger Trott Source Type: research

Ionizing radiation exposure effects across multiple generations: evidence and lessons from non-human biota
In this report, we summarize the evidence of multi- and trans-generational effects in non-human biota species that was discussed at the ICRP workshop entitled "Effects of Ionizing Radiation Exposure in Offspring and Next Generations" in June 2022. Epigenetic changes, including changes in DNA methylation, have been observed in trans- and multi-generational irradiation studies in both plants and animals. There were also reports of changes in offspring survival and reproduction. The reported evidence for altered reproduction is an area of potential concern, due to possible effects at the population or ecosystem level. Differe...
Source: International Journal of Radiation Biology - December 11, 2023 Category: Radiology Authors: Shayenthiran Sreetharan Sandrine Frelon Nele Horemans Patrick Laloi Sisko Salomaa Christelle Adam-Guillermin Source Type: research

Epidemiological and experimental evidence for radiation-induced health effects in the progeny after exposure in utero
CONCLUSION: There is no convincing evidence, neither from epidemiological nor experimental data of the existence of a dose threshold for developmental defects after radiation exposure in utero. This must be taken into account in the revision of rules and regulations of radiation protection in medicine.PMID:38079348 | DOI:10.1080/09553002.2023.2283088 (Source: International Journal of Radiation Biology)
Source: International Journal of Radiation Biology - December 11, 2023 Category: Radiology Authors: Mohammed Abderrafi Benotmane Klaus Ruediger Trott Source Type: research

Ionizing radiation exposure effects across multiple generations: evidence and lessons from non-human biota
In this report, we summarize the evidence of multi- and trans-generational effects in non-human biota species that was discussed at the ICRP workshop entitled "Effects of Ionizing Radiation Exposure in Offspring and Next Generations" in June 2022. Epigenetic changes, including changes in DNA methylation, have been observed in trans- and multi-generational irradiation studies in both plants and animals. There were also reports of changes in offspring survival and reproduction. The reported evidence for altered reproduction is an area of potential concern, due to possible effects at the population or ecosystem level. Differe...
Source: International Journal of Radiation Biology - December 11, 2023 Category: Radiology Authors: Shayenthiran Sreetharan Sandrine Frelon Nele Horemans Patrick Laloi Sisko Salomaa Christelle Adam-Guillermin Source Type: research

Epidemiological and experimental evidence for radiation-induced health effects in the progeny after exposure in utero
CONCLUSION: There is no convincing evidence, neither from epidemiological nor experimental data of the existence of a dose threshold for developmental defects after radiation exposure in utero. This must be taken into account in the revision of rules and regulations of radiation protection in medicine.PMID:38079348 | DOI:10.1080/09553002.2023.2283088 (Source: International Journal of Radiation Biology)
Source: International Journal of Radiation Biology - December 11, 2023 Category: Radiology Authors: Mohammed Abderrafi Benotmane Klaus Ruediger Trott Source Type: research

Ionizing radiation exposure effects across multiple generations: evidence and lessons from non-human biota
In this report, we summarize the evidence of multi- and trans-generational effects in non-human biota species that was discussed at the ICRP workshop entitled "Effects of Ionizing Radiation Exposure in Offspring and Next Generations" in June 2022. Epigenetic changes, including changes in DNA methylation, have been observed in trans- and multi-generational irradiation studies in both plants and animals. There were also reports of changes in offspring survival and reproduction. The reported evidence for altered reproduction is an area of potential concern, due to possible effects at the population or ecosystem level. Differe...
Source: International Journal of Radiation Biology - December 11, 2023 Category: Radiology Authors: Shayenthiran Sreetharan Sandrine Frelon Nele Horemans Patrick Laloi Sisko Salomaa Christelle Adam-Guillermin Source Type: research

Epidemiological and experimental evidence for radiation-induced health effects in the progeny after exposure in utero
CONCLUSION: There is no convincing evidence, neither from epidemiological nor experimental data of the existence of a dose threshold for developmental defects after radiation exposure in utero. This must be taken into account in the revision of rules and regulations of radiation protection in medicine.PMID:38079348 | DOI:10.1080/09553002.2023.2283088 (Source: International Journal of Radiation Biology)
Source: International Journal of Radiation Biology - December 11, 2023 Category: Radiology Authors: Mohammed Abderrafi Benotmane Klaus Ruediger Trott Source Type: research

Ionizing radiation exposure effects across multiple generations: evidence and lessons from non-human biota
In this report, we summarize the evidence of multi- and trans-generational effects in non-human biota species that was discussed at the ICRP workshop entitled "Effects of Ionizing Radiation Exposure in Offspring and Next Generations" in June 2022. Epigenetic changes, including changes in DNA methylation, have been observed in trans- and multi-generational irradiation studies in both plants and animals. There were also reports of changes in offspring survival and reproduction. The reported evidence for altered reproduction is an area of potential concern, due to possible effects at the population or ecosystem level. Differe...
Source: International Journal of Radiation Biology - December 11, 2023 Category: Radiology Authors: Shayenthiran Sreetharan Sandrine Frelon Nele Horemans Patrick Laloi Sisko Salomaa Christelle Adam-Guillermin Source Type: research