International Journal of Radiation Biology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Neoplasia-related and treatment-induced lymphopenia: impact on the outcome of chemoradiotherapy in laryngeal cancer
CONCLUSIONS: Both neoplasia-related and RT-induced lymphopenia define the outcome of RT in terms of locoregional failure, incidence of metastasis, and, finally, disease-specific survival of patients with laryngeal cancer. Restoration of pre-RT lymphopenia and protection of peripheral lymphocytes during RT emerge as critical issues that demand therapeutic interventions to maximize the efficacy of RT/CRT in patients with laryngeal cancer.PMID:38394349 | DOI:10.1080/09553002.2024.2316608 (Source: International Journal of Radiation Biology)
Source: International Journal of Radiation Biology - February 23, 2024 Category: Radiology Authors: Ioannis M Koukourakis Anastasia G Gkegka Alexandra Giatromanolaki Michael I Koukourakis Source Type: research

Lessons on harmonization of scoring criteria for dicentric chromosome assay in South Korea
CONCLUSIONS: We identified potential resistance to following the harmonized guidelines and received requests for more detailed methods. Our findings suggest that the harmonized criteria should be continually updated, and education and training should be provided for all scorers. These changes could allow members within the biodosimetry network to successfully collaborate and support each other in large-scale radiological accidents.PMID:38394348 | DOI:10.1080/09553002.2024.2316603 (Source: International Journal of Radiation Biology)
Source: International Journal of Radiation Biology - February 23, 2024 Category: Radiology Authors: Yang Hee Lee Hyo Jin Yoon Su San Yang In Kyung Lee Wol Soon Jo Soo Kyung Jeong Su Jung Oh Jiin Kim Younghyun Lee Ki Moon Seong Source Type: research

A systematic review of human evidence for the intergenerational effects of exposure to ionizing radiation
CONCLUSIONS: We find there to be a lack of evidence to enable the formal assessment of radiation-related adverse effects in offspring of exposed humans. This is not the same as there being no clear evidence that effects may occur but does infer that if adverse health effects do arise in children of exposed parents, then these effects are small and difficult to reproducibly measure. Inconsistencies in designing studies are unavoidable, however we highlight the need for an element of standardization and, more sharing of primary datasets as part of open access initiatives, in order for future reviews to make reasonable conclu...
Source: International Journal of Radiation Biology - February 9, 2024 Category: Radiology Authors: Jade Stephens Alexander J Moorhouse Kai Craenen Ewald Schroeder Fotios Drenos Rhona Anderson Source Type: research

Deciphering induced variability, character association and multivariate analysis utilizing gamma rays and ethyl methanesulfonate in bread wheat ( < em > Triticum aestivum < /em > L.) genotypes with differential grain texture
CONCLUSIONS: Assessment of mutagen sensitivity showed that semi-hard wheat varieties were responsive to both mutagens, particularly EMS and generated higher variability and divergence than the soft textured varieties. Hence, gamma rays were proved to be more effective in generating higher variability than ethyl methanesulfonate. A total of 117 putative mutants were identified with desirable agro-morphological attributes. Among these, mutants with higher inter-cluster distance can be used as parents in hybridization programs and serve as important genetic resources in future wheat improvement programs.PMID:38319050 | DOI:10...
Source: International Journal of Radiation Biology - February 6, 2024 Category: Radiology Authors: Amit Rana Vijay Rana Suman Bakshi Vinod Kumar Sood None Priyanka None Anuradha Source Type: research

Modifications of DAMPs levels in extracellular environment induced by aminolevulinic acid-based photodynamic therapy of esophageal cancer cells
CONCLUSION: Aminolevulinic acid-based photodynamic therapy leads to alterations in local extracellular levels of damage associated molecular patterns, however, comprehensive studies are needed to find whether they can be responsible for macrophage phenotype modifications.PMID:38319688 | DOI:10.1080/09553002.2024.2310002 (Source: International Journal of Radiation Biology)
Source: International Journal of Radiation Biology - February 6, 2024 Category: Radiology Authors: Beata Čunderlíková Krist ína Klučková Pavel Bab ál Peter Mlkv ý Tibor Teplick ý Source Type: research

Intergenerational effects of ionizing radiation: review of recent studies from human data (2018-2021)
CONCLUSION: This review, covering the period 2018-2022, serves as an extension of the previous systematic review conducted by Stephens et al. (2024), which encompassed the years 1988-2018. Together, these two papers offer a comprehensive overview of the available evidence regarding the intergenerational effects of parental pre-conceptional exposure to ionizing radiation. Overall, the findings do not provide strong evidence supporting a significant association between adverse (or other) outcomes in unexposed children and parental preconception radiation exposure.PMID:38319708 | DOI:10.1080/09553002.2024.2309917 (Source: Int...
Source: International Journal of Radiation Biology - February 6, 2024 Category: Radiology Authors: A Amrenova C Baudin E Ostroumova J Stephens R Anderson D Laurier Source Type: research

High variability in short and long-term recovery kinetic of blood cell count and blood chemistry in a partial body irradiation mouse model
CONCLUSIONS: Irradiated animals had significant depletion of white blood cells, red blood cells and platelets up to 10 days post-irradiation. Separation between PBI and WBI were observed at 10- and 20-days post-irradiation at which point PBI animals showed sign of recovery while overall cell count remains depleted in WBI animals up to 30 days post-irradiation. In addition, significant changes were found in parameters indicative of hematopoietic injury including hemoglobin count, hematocrit count and white blood cell population. Significant changes were observed in kidney function with changes to blood urea nitrogen and cal...
Source: International Journal of Radiation Biology - February 2, 2024 Category: Radiology Authors: Tien T Tang Janice A Zawaski Omaima M Sabek M Waleed Gaber Source Type: research

Alleviation of radiation combined skin injury in rat model by topical application of ascorbate formulation
CONCLUSION: Topical application of the ascorbate formulation in RCI resulted in a significant improvement in delayed wound healing, leading to accelerated wound closure by mitigating the expression of inflammatory responses.PMID:38306495 | DOI:10.1080/09553002.2024.2310016 (Source: International Journal of Radiation Biology)
Source: International Journal of Radiation Biology - February 2, 2024 Category: Radiology Authors: Ajay Kumar Sharma Aman Kalonia Rishav Kumar None Kirti Priyanka Shaw M H Yashvarddhan Arpana Vibhuti Sandeep Kumar Shukla Source Type: research

Phenotypic and transcriptional changes in lens epithelial cells following acute and fractionated ionizing radiation exposure
CONCLUSIONS: Overall, this research provides novel insights into the dose and fractionation effects on functional changes and transcriptional regulatory networks in LEC, furthering our understanding of the mechanisms behind radiation induced cataracts.PMID:38289679 | DOI:10.1080/09553002.2023.2295965 (Source: International Journal of Radiation Biology)
Source: International Journal of Radiation Biology - January 30, 2024 Category: Radiology Authors: Graysen Vigneux Taylor Laframboise Sujeenthar Tharmalingam Christopher Thome Source Type: research