Managing dyslipidaemia in young adults
Indian Heart J. 2024 Feb 12:S0019-4832(23)00456-X. doi: 10.1016/j.ihj.2023.11.265. Online ahead of print.ABSTRACTIndians have early onset atherosclerotic cardiovascular disease and acquire the risk factors at a younger age, and hence we need to aggressively address the management of dyslipidemia in the young. Cholesterol levels early in life will influence the development of atherosclerosis. Young atherosclerotic cardiovascular disease (ASCVD) patients (18-40 yrs) should receive lipid-lowering drugs to reduce LDL-C<55 mg. Due to the asymptomatic nature of dyslipidemia, early screening will enable the implementation of m...
Source: Indian Heart J - February 15, 2024 Category: Cardiology Authors: Jamshed J Dalal Tabassum Khan Source Type: research
Trends in epidemiology of dyslipidemias in India
Indian Heart J. 2024 Feb 12:S0019-4832(23)00457-1. doi: 10.1016/j.ihj.2023.11.266. Online ahead of print.ABSTRACTDyslipidemias are the most important coronary artery disease (CAD) risk factor. High total cholesterol and its principal subtypes: low-density lipoprotein (LDL) cholesterol and non-high-density lipoprotein (NHDL) cholesterol are the most important. Epidemiological and Mendelian randomization studies have confirmed role of raised triglycerides and lipoprotein(a). INTERHEART study reported a significant association of raised ApoB/ApoA1, total-, LDL-, and NHDL-cholesterol in South Asians. Prospective Urban Rural Ep...
Source: Indian Heart J - February 15, 2024 Category: Cardiology Authors: Sonali Sharma Kiran Gaur Rajeev Gupta Source Type: research
Managing dyslipidaemia in young adults
Indian Heart J. 2024 Feb 12:S0019-4832(23)00456-X. doi: 10.1016/j.ihj.2023.11.265. Online ahead of print.ABSTRACTIndians have early onset atherosclerotic cardiovascular disease and acquire the risk factors at a younger age, and hence we need to aggressively address the management of dyslipidemia in the young. Cholesterol levels early in life will influence the development of atherosclerosis. Young atherosclerotic cardiovascular disease (ASCVD) patients (18-40 yrs) should receive lipid-lowering drugs to reduce LDL-C<55 mg. Due to the asymptomatic nature of dyslipidemia, early screening will enable the implementation of m...
Source: Indian Heart J - February 15, 2024 Category: Cardiology Authors: Jamshed J Dalal Tabassum Khan Source Type: research
Trends in epidemiology of dyslipidemias in India
Indian Heart J. 2024 Feb 12:S0019-4832(23)00457-1. doi: 10.1016/j.ihj.2023.11.266. Online ahead of print.ABSTRACTDyslipidemias are the most important coronary artery disease (CAD) risk factor. High total cholesterol and its principal subtypes: low-density lipoprotein (LDL) cholesterol and non-high-density lipoprotein (NHDL) cholesterol are the most important. Epidemiological and Mendelian randomization studies have confirmed role of raised triglycerides and lipoprotein(a). INTERHEART study reported a significant association of raised ApoB/ApoA1, total-, LDL-, and NHDL-cholesterol in South Asians. Prospective Urban Rural Ep...
Source: Indian Heart J - February 15, 2024 Category: Cardiology Authors: Sonali Sharma Kiran Gaur Rajeev Gupta Source Type: research
Managing dyslipidaemia in young adults
Indian Heart J. 2024 Feb 12:S0019-4832(23)00456-X. doi: 10.1016/j.ihj.2023.11.265. Online ahead of print.ABSTRACTIndians have early onset atherosclerotic cardiovascular disease and acquire the risk factors at a younger age, and hence we need to aggressively address the management of dyslipidemia in the young. Cholesterol levels early in life will influence the development of atherosclerosis. Young atherosclerotic cardiovascular disease (ASCVD) patients (18-40 yrs) should receive lipid-lowering drugs to reduce LDL-C<55 mg. Due to the asymptomatic nature of dyslipidemia, early screening will enable the implementation of m...
Source: Indian Heart J - February 15, 2024 Category: Cardiology Authors: Jamshed J Dalal Tabassum Khan Source Type: research
Trends in epidemiology of dyslipidemias in India
Indian Heart J. 2024 Feb 12:S0019-4832(23)00457-1. doi: 10.1016/j.ihj.2023.11.266. Online ahead of print.ABSTRACTDyslipidemias are the most important coronary artery disease (CAD) risk factor. High total cholesterol and its principal subtypes: low-density lipoprotein (LDL) cholesterol and non-high-density lipoprotein (NHDL) cholesterol are the most important. Epidemiological and Mendelian randomization studies have confirmed role of raised triglycerides and lipoprotein(a). INTERHEART study reported a significant association of raised ApoB/ApoA1, total-, LDL-, and NHDL-cholesterol in South Asians. Prospective Urban Rural Ep...
Source: Indian Heart J - February 15, 2024 Category: Cardiology Authors: Sonali Sharma Kiran Gaur Rajeev Gupta Source Type: research
Managing dyslipidaemia in young adults
Indian Heart J. 2024 Feb 12:S0019-4832(23)00456-X. doi: 10.1016/j.ihj.2023.11.265. Online ahead of print.ABSTRACTIndians have early onset atherosclerotic cardiovascular disease and acquire the risk factors at a younger age, and hence we need to aggressively address the management of dyslipidemia in the young. Cholesterol levels early in life will influence the development of atherosclerosis. Young atherosclerotic cardiovascular disease (ASCVD) patients (18-40 yrs) should receive lipid-lowering drugs to reduce LDL-C<55 mg. Due to the asymptomatic nature of dyslipidemia, early screening will enable the implementation of m...
Source: Indian Heart J - February 15, 2024 Category: Cardiology Authors: Jamshed J Dalal Tabassum Khan Source Type: research
Trends in epidemiology of dyslipidemias in India
Indian Heart J. 2024 Feb 12:S0019-4832(23)00457-1. doi: 10.1016/j.ihj.2023.11.266. Online ahead of print.ABSTRACTDyslipidemias are the most important coronary artery disease (CAD) risk factor. High total cholesterol and its principal subtypes: low-density lipoprotein (LDL) cholesterol and non-high-density lipoprotein (NHDL) cholesterol are the most important. Epidemiological and Mendelian randomization studies have confirmed role of raised triglycerides and lipoprotein(a). INTERHEART study reported a significant association of raised ApoB/ApoA1, total-, LDL-, and NHDL-cholesterol in South Asians. Prospective Urban Rural Ep...
Source: Indian Heart J - February 15, 2024 Category: Cardiology Authors: Sonali Sharma Kiran Gaur Rajeev Gupta Source Type: research
Managing dyslipidaemia in young adults
Indian Heart J. 2024 Feb 12:S0019-4832(23)00456-X. doi: 10.1016/j.ihj.2023.11.265. Online ahead of print.ABSTRACTIndians have early onset atherosclerotic cardiovascular disease and acquire the risk factors at a younger age, and hence we need to aggressively address the management of dyslipidemia in the young. Cholesterol levels early in life will influence the development of atherosclerosis. Young atherosclerotic cardiovascular disease (ASCVD) patients (18-40 yrs) should receive lipid-lowering drugs to reduce LDL-C<55 mg. Due to the asymptomatic nature of dyslipidemia, early screening will enable the implementation of m...
Source: Indian Heart J - February 15, 2024 Category: Cardiology Authors: Jamshed J Dalal Tabassum Khan Source Type: research
Trends in epidemiology of dyslipidemias in India
Indian Heart J. 2024 Feb 12:S0019-4832(23)00457-1. doi: 10.1016/j.ihj.2023.11.266. Online ahead of print.ABSTRACTDyslipidemias are the most important coronary artery disease (CAD) risk factor. High total cholesterol and its principal subtypes: low-density lipoprotein (LDL) cholesterol and non-high-density lipoprotein (NHDL) cholesterol are the most important. Epidemiological and Mendelian randomization studies have confirmed role of raised triglycerides and lipoprotein(a). INTERHEART study reported a significant association of raised ApoB/ApoA1, total-, LDL-, and NHDL-cholesterol in South Asians. Prospective Urban Rural Ep...
Source: Indian Heart J - February 15, 2024 Category: Cardiology Authors: Sonali Sharma Kiran Gaur Rajeev Gupta Source Type: research
Managing dyslipidaemia in young adults
Indian Heart J. 2024 Feb 12:S0019-4832(23)00456-X. doi: 10.1016/j.ihj.2023.11.265. Online ahead of print.ABSTRACTIndians have early onset atherosclerotic cardiovascular disease and acquire the risk factors at a younger age, and hence we need to aggressively address the management of dyslipidemia in the young. Cholesterol levels early in life will influence the development of atherosclerosis. Young atherosclerotic cardiovascular disease (ASCVD) patients (18-40 yrs) should receive lipid-lowering drugs to reduce LDL-C<55 mg. Due to the asymptomatic nature of dyslipidemia, early screening will enable the implementation of m...
Source: Indian Heart J - February 15, 2024 Category: Cardiology Authors: Jamshed J Dalal Tabassum Khan Source Type: research
Association of LDL-C/HDL-C ratio with coronary heart disease: A meta-analysis
CONCLUSION: The LHR was found to be positively correlated with CHD, suggesting that it may serve as a potential indicator of CHD.PMID:38342141 | DOI:10.1016/j.ihj.2024.01.014 (Source: Indian Heart J)
Source: Indian Heart J - February 11, 2024 Category: Cardiology Authors: Siqi Hu Hua Fan Shenghui Zhang Chen Chen Yao You Chunyi Wang Jie Li Lin Luo Yongran Cheng Mengyun Zhou Xuezhi Zhao Wen Wen Tao Tan Fangfang Xu Xinyan Fu Juan Chen Xingwei Zhang Mingwei Wang Jiake Tang Source Type: research
Management of dyslipidemia in special groups
Indian Heart J. 2024 Feb 8:S0019-4832(24)00018-X. doi: 10.1016/j.ihj.2024.01.018. Online ahead of print.ABSTRACTDyslipidemia management in situations like pregnancy, in diseases like rheumatoid arthritis, human immunodeficiency virus (HIV) disease, chronic liver disease, and in the elderly are challenging scenarios. Pregnancy is a contraindication for many drugs. The interaction of various drugs used in HIV infection and rheumatoid arthritis makes it even more difficult to treat with conventional and approved drugs for dyslipidemia. Elderly and chronic renal failure patients often do not tolerate the drugs very well and th...
Source: Indian Heart J - February 9, 2024 Category: Cardiology Authors: Jayagopal P B Prafulla G Kerkar Source Type: research
Dyslipidaemia in elderly and stroke patients
Indian Heart J. 2024 Feb 2:S0019-4832(24)00013-0. doi: 10.1016/j.ihj.2024.01.013. Online ahead of print.ABSTRACTLowering of cholesterol containing atherogenic particles through lipid lowering therapies is of outmost important in both in the elderly age group and younger age group in reducing the cardiovascular risk. This chapter summarizes the current existing knowledge regarding the factors which affects the key decision-making process in patients with older age, and also in special circumstance where the direct evidence of benefit for cholesterol lowering is lacking. Effort has been made to briefly summarize the recommen...
Source: Indian Heart J - February 3, 2024 Category: Cardiology Authors: Dhiman Kahali Source Type: research
Endothelial nitric oxide synthase (eNOS) gene polymorphism (Glu298asp) and nitric oxide (NO) levels in patients with ST-segment elevation myocardial infarction (STEMI)
CONCLUSION: There was significant association of eNOS gene polymorphism Glu298Asp with STEMI patients > 40 years. However, this association was not observed in premature CAD patients. Lower levels of NO in STEMI patients >40 years suggests its potential role as a marker of CVD.PMID:38309470 | DOI:10.1016/j.ihj.2024.01.017 (Source: Indian Heart J)
Source: Indian Heart J - February 3, 2024 Category: Cardiology Authors: Mohit Dayal Gupta Cherian Akkarappatty Shekhar Kunal Girish Mp Ankit Bansal Vishal Batra Sanjay Tyagi Source Type: research
