Apolipoprotein B - An ideal biomarker for atherosclerosis?
Indian Heart J. 2024 Mar;76 Suppl 1:S121-S129. doi: 10.1016/j.ihj.2023.12.001. Epub 2024 Apr 8.ABSTRACTThis review article describes the pathophysiological mechanisms linking Apolipoprotein B (Apo-B) and atherosclerosis, summarizes the existing evidence on Apo B as a predictor of atherosclerotic cardiovascular disease and recommendations of (inter)national treatment guidelines regarding Apo B in dyslipidemia management. A single Apo B molecule is present in every particle of very low-density lipoprotein, intermediate density lipoprotein, low density lipoprotein, and lipoprotein(a). This unique single Apo B per particle rat...
Source: Indian Heart J - April 10, 2024 Category: Cardiology Authors: Kavita Singh Dorairaj Prabhakaran Source Type: research
Role of statins in the management of dyslipidaemia
Indian Heart J. 2024 Mar;76 Suppl 1:S33-S37. doi: 10.1016/j.ihj.2023.11.267. Epub 2024 Apr 8.ABSTRACTBlood cholesterol has firmly been established as a crucial risk factor for the development of atherosclerotic cardiovascular disease (ASCVD) by elegant epidemiological studies. Naturally, means to reduce blood cholesterol level took the centerstage of research in this field. After initial lukewarm results with nicotinic acid, fibrates and some other agents, statins emerged as the most effective class of medicine to reduce blood cholesterol; in particular, the most atherogenic low density lipoprotein cholesterol (LDL-C). Als...
Source: Indian Heart J - April 10, 2024 Category: Cardiology Authors: Saumitra Ray Source Type: research
Exercise and lipids
Indian Heart J. 2024 Mar;76 Suppl 1:S73-S74. doi: 10.1016/j.ihj.2023.11.270. Epub 2024 Apr 8.ABSTRACTEvidence from the existing literature suggests that exercise has positive effects for prevention and treatment of cardiovascular diseases by reducing risk factors such as elevated blood lipids. Based on clinical and observational clinical trials, it is well established that increased physical activity and regular exercise has a favourable impact on blood lipids and lipoprotein profiles. Exercise training significantly decreases blood triglycerides concentration and increases high density lipoprotein cholesterol levels. Thou...
Source: Indian Heart J - April 10, 2024 Category: Cardiology Authors: Kushal Madan J P S Sawhney Source Type: research
Relationship between high sensitivity troponin I and clinical outcomes in non-acute coronary syndrome (non-ACS) acute heart failure patients - a one-year follow-up study
CONCLUSION: High-sensitivity troponin I is a valuable biomarker that can predict in-hospital mortality and long-term follow-up outcomes in patients with acute heart failure. It plays a crucial role in developing improved strategies for heart failure surveillance and management in the community.PMID:38599282 | DOI:10.1016/j.ihj.2024.04.003 (Source: Indian Heart J)
Source: Indian Heart J - April 10, 2024 Category: Cardiology Authors: Dr Abhishek Kumar Dr Kader Muneer Dr Naeem Qureshi Source Type: research
Pediatric hyperlipidemia
This article emphasizes the diagnosis and management of pediatric hyperlipidemia with reference to the recent guidelines. In terms of etiology pediatric hyperlipidemia are divided into primary and secondary causes. The mainstay of management includes high-risk target screening, early risk factor identification and lifestyle modifications in vulnerable population. Drug therapy is recommended in primary hyperlipidemia and in children with no response to lifestyle changes.PMID:38599724 | DOI:10.1016/j.ihj.2023.11.269 (Source: Indian Heart J)
Source: Indian Heart J - April 10, 2024 Category: Cardiology Authors: Ankit Garg S Radhakrishnan Source Type: research
Familial hypercholesterolemia
Indian Heart J. 2024 Mar;76 Suppl 1:S108-S112. doi: 10.1016/j.ihj.2023.12.002. Epub 2024 Apr 8.ABSTRACTFamilial hypercholesterolemia is a common genetic disorder of autosomal inheritance associated with elevated LDL-cholesterol. It is estimated to affect 1:250 individuals in general population roughly estimated to be 5 million in India. The prevalence of FH is higher in young CAD patients (<55 years in men; <60 years in women). FH is underdiagnosed and undertreated. Screening during childhood and Cascade screening of family members of known FH patients is of utmost importance in order to prevent the burden of CAD. Ea...
Source: Indian Heart J - April 10, 2024 Category: Cardiology Authors: J P S Sawhney Kushal Madan Source Type: research
Apolipoprotein B - An ideal biomarker for atherosclerosis?
Indian Heart J. 2024 Mar;76 Suppl 1:S121-S129. doi: 10.1016/j.ihj.2023.12.001. Epub 2024 Apr 8.ABSTRACTThis review article describes the pathophysiological mechanisms linking Apolipoprotein B (Apo-B) and atherosclerosis, summarizes the existing evidence on Apo B as a predictor of atherosclerotic cardiovascular disease and recommendations of (inter)national treatment guidelines regarding Apo B in dyslipidemia management. A single Apo B molecule is present in every particle of very low-density lipoprotein, intermediate density lipoprotein, low density lipoprotein, and lipoprotein(a). This unique single Apo B per particle rat...
Source: Indian Heart J - April 10, 2024 Category: Cardiology Authors: Kavita Singh Dorairaj Prabhakaran Source Type: research
Role of statins in the management of dyslipidaemia
Indian Heart J. 2024 Mar;76 Suppl 1:S33-S37. doi: 10.1016/j.ihj.2023.11.267. Epub 2024 Apr 8.ABSTRACTBlood cholesterol has firmly been established as a crucial risk factor for the development of atherosclerotic cardiovascular disease (ASCVD) by elegant epidemiological studies. Naturally, means to reduce blood cholesterol level took the centerstage of research in this field. After initial lukewarm results with nicotinic acid, fibrates and some other agents, statins emerged as the most effective class of medicine to reduce blood cholesterol; in particular, the most atherogenic low density lipoprotein cholesterol (LDL-C). Als...
Source: Indian Heart J - April 10, 2024 Category: Cardiology Authors: Saumitra Ray Source Type: research
Exercise and lipids
Indian Heart J. 2024 Mar;76 Suppl 1:S73-S74. doi: 10.1016/j.ihj.2023.11.270. Epub 2024 Apr 8.ABSTRACTEvidence from the existing literature suggests that exercise has positive effects for prevention and treatment of cardiovascular diseases by reducing risk factors such as elevated blood lipids. Based on clinical and observational clinical trials, it is well established that increased physical activity and regular exercise has a favourable impact on blood lipids and lipoprotein profiles. Exercise training significantly decreases blood triglycerides concentration and increases high density lipoprotein cholesterol levels. Thou...
Source: Indian Heart J - April 10, 2024 Category: Cardiology Authors: Kushal Madan J P S Sawhney Source Type: research
Indexing of Left Atrial Volume by various body size parameters in the Indian non-obese normal subjects: Is there an incremental value ?
CONCLUSION: Normal values for LAV indexed for height, weight, body surface area by three different methods of height as an allometric parameter are described in normal Indian individuals. We reinforce that LA volume indexation for BSA is an acceptable and robust method in non-obese Indian subjects. Indexing for height 1.72 is probably slightly superior method to evaluate LAV.PMID:38574812 | DOI:10.1016/j.ihj.2024.04.001 (Source: Indian Heart J)
Source: Indian Heart J - April 4, 2024 Category: Cardiology Authors: Shantanu P Sengupta Jagdish Chander Mohan Dhananjay Raje Nitin Burkule Madhu Shukla Source Type: research
Epidemiological profile and clinical outcomes of very young ( & lt;35 years) and young (35-50 years) patients with STEMI: Insights from the NORIN STEMI registry
CONCLUSIONS: Young STEMI patients constituted one-third of total cohort. Most of them were tobacco consumers with lesser prevalence of diabetes and hypertension. They were less likely to die both in-hospital and at 30 days because of earlier presentation to a health care facility and hence a relatively preserved LVEF.PMID:38574813 | DOI:10.1016/j.ihj.2024.04.002 (Source: Indian Heart J)
Source: Indian Heart J - April 4, 2024 Category: Cardiology Authors: Mohit D Gupta Vishal Batra Subrat Muduli Girish Mp Shekhar Kunal Ankit Bansal Safal Ankur Gautam Rajeev Kumar Malhotra Dixit Goyal Arman Qamar Jamal Yusuf Source Type: research
Indexing of Left Atrial Volume by various body size parameters in the Indian non-obese normal subjects: Is there an incremental value ?
CONCLUSION: Normal values for LAV indexed for height, weight, body surface area by three different methods of height as an allometric parameter are described in normal Indian individuals. We reinforce that LA volume indexation for BSA is an acceptable and robust method in non-obese Indian subjects. Indexing for height 1.72 is probably slightly superior method to evaluate LAV.PMID:38574812 | DOI:10.1016/j.ihj.2024.04.001 (Source: Indian Heart J)
Source: Indian Heart J - April 4, 2024 Category: Cardiology Authors: Shantanu P Sengupta Jagdish Chander Mohan Dhananjay Raje Nitin Burkule Madhu Shukla Source Type: research
Epidemiological profile and clinical outcomes of very young ( & lt;35 years) and young (35-50 years) patients with STEMI: Insights from the NORIN STEMI registry
CONCLUSIONS: Young STEMI patients constituted one-third of total cohort. Most of them were tobacco consumers with lesser prevalence of diabetes and hypertension. They were less likely to die both in-hospital and at 30 days because of earlier presentation to a health care facility and hence a relatively preserved LVEF.PMID:38574813 | DOI:10.1016/j.ihj.2024.04.002 (Source: Indian Heart J)
Source: Indian Heart J - April 4, 2024 Category: Cardiology Authors: Mohit D Gupta Vishal Batra Subrat Muduli Girish Mp Shekhar Kunal Ankit Bansal Safal Ankur Gautam Rajeev Kumar Malhotra Dixit Goyal Arman Qamar Jamal Yusuf Source Type: research
Indexing of Left Atrial Volume by various body size parameters in the Indian non-obese normal subjects: Is there an incremental value ?
CONCLUSION: Normal values for LAV indexed for height, weight, body surface area by three different methods of height as an allometric parameter are described in normal Indian individuals. We reinforce that LA volume indexation for BSA is an acceptable and robust method in non-obese Indian subjects. Indexing for height 1.72 is probably slightly superior method to evaluate LAV.PMID:38574812 | DOI:10.1016/j.ihj.2024.04.001 (Source: Indian Heart J)
Source: Indian Heart J - April 4, 2024 Category: Cardiology Authors: Shantanu P Sengupta Jagdish Chander Mohan Dhananjay Raje Nitin Burkule Madhu Shukla Source Type: research
Epidemiological profile and clinical outcomes of very young ( & lt;35 years) and young (35-50 years) patients with STEMI: Insights from the NORIN STEMI registry
CONCLUSIONS: Young STEMI patients constituted one-third of total cohort. Most of them were tobacco consumers with lesser prevalence of diabetes and hypertension. They were less likely to die both in-hospital and at 30 days because of earlier presentation to a health care facility and hence a relatively preserved LVEF.PMID:38574813 | DOI:10.1016/j.ihj.2024.04.002 (Source: Indian Heart J)
Source: Indian Heart J - April 4, 2024 Category: Cardiology Authors: Mohit D Gupta Vishal Batra Subrat Muduli Girish Mp Shekhar Kunal Ankit Bansal Safal Ankur Gautam Rajeev Kumar Malhotra Dixit Goyal Arman Qamar Jamal Yusuf Source Type: research
