Monocyte alteration in elderly hip fracture healing: monocyte promising role in bone regeneration
Individual aged with various change in cell and cellular microenvironments and the skeletal system undergoes physiological changes that affect the process of bone fracture healing. These changes are accompanie... (Source: Immunity and Aging)
Source: Immunity and Aging - February 3, 2024 Category: Geriatrics Authors: Clement Shema, Yining Lu, Ling Wang and Yingze Zhang Tags: Review Source Type: research
Chitosan alleviates ovarian aging by enhancing macrophage phagocyte-mediated tissue homeostasis
Age-related changes in the ovarian microenvironment are linked to impaired fertility in women. Macrophages play important roles in ovarian tissue homeostasis and immune surveillance. However, the impact of agi... (Source: Immunity and Aging)
Source: Immunity and Aging - January 27, 2024 Category: Geriatrics Authors: Hui-Hui Shen, Xin-Yan Zhang, Nan Liu, Yang-Yang Zhang, Hui-Hua Wu, Feng Xie, Wen-Jun Wang and Ming-Qing Li Tags: Research Source Type: research
Antibody and transcription landscape in peripheral blood mononuclear cells of elderly adults over 70 years of age with third dose of COVID-19 BBIBP-CorV and ZF2001 booster vaccine
In the context of the COVID-19 pandemic and extensive vaccination, it is important to explore the immune response of elderly adults to homologous and heterologous booster vaccines of COVID-19. At this point, w... (Source: Immunity and Aging)
Source: Immunity and Aging - January 27, 2024 Category: Geriatrics Authors: Yuwei Zhang, Lianxiang Zhao, Jinzhong Zhang, Xiaomei Zhang, Shanshan Han, Qingshuai Sun, Mingxiao Yao, Bo Pang, Qing Duan and Xiaolin Jiang Tags: Research Source Type: research
sCD163, sCD28, sCD80, and sCTLA-4 as soluble marker candidates for detecting immunosenescence
Inflammaging, the characteristics of immunosenescence, characterized by continuous chronic inflammation that could not be resolved. It is not only affect older people but can also occur in young individuals, ... (Source: Immunity and Aging)
Source: Immunity and Aging - January 20, 2024 Category: Geriatrics Authors: Andrea Aprilia, Kusworini Handono, Hidayat Sujuti, Akhmad Sabarudin and Nuning Winaris Tags: Review Source Type: research
Correction: A genomic perspective of the aging human and mouse lung with a focus on immune response and cellular senescence
(Source: Immunity and Aging)
Source: Immunity and Aging - January 16, 2024 Category: Geriatrics Authors: Meng He and J ürgen Borlak Tags: Correction Source Type: research
Growth and longevity modulation through larval environment mediate immunosenescence and immune strategy of Tenebrio molitor
The Disposable Soma Theory of aging suggests a trade-off between energy allocation for growth, reproduction and somatic maintenance, including immunity. While trade-offs between reproduction and immunity are w... (Source: Immunity and Aging)
Source: Immunity and Aging - January 12, 2024 Category: Geriatrics Authors: Agathe Crosland, Thierry Rigaud, Charl ène Develay and Yannick Moret Tags: Research Source Type: research
Accelarated immune ageing is associated with COVID-19 disease severity
The striking increase in COVID-19 severity in older adults provides a clear example of immunesenescence, the age-related remodelling of the immune system. To better characterise the association between convale... (Source: Immunity and Aging)
Source: Immunity and Aging - January 11, 2024 Category: Geriatrics Authors: Janet M. Lord, Tonny Veenith, Jack Sullivan, Archana Sharma-Oates, Alex G. Richter, Neil J. Greening, Hamish J. C. McAuley, Rachael A. Evans, Paul Moss, Shona C. Moore, Lance Turtle, Nandan Gautam, Ahmed Gilani, Manan Bajaj, Louise V. Wain, Christopher Br Tags: Research Source Type: research
Neuroimmunology and ageing – the state of the art
(Source: Immunity and Aging)
Source: Immunity and Aging - January 10, 2024 Category: Geriatrics Authors: Mois és E. Bauer, Graham Pawelec and Roberto Paganelli Tags: Matters Arising Source Type: research
Inflammatory markers and physical frailty: towards clinical application
Global population aging poses a tremendous burden on the health care system worldwide. Frailty is associated with decreased physical reserve and is considered an important indicator of adverse events in the ol... (Source: Immunity and Aging)
Source: Immunity and Aging - January 6, 2024 Category: Geriatrics Authors: Yiming Pan and Lina Ma Tags: Review Source Type: research
Helicobacter pylori infection and Parkinson ’s Disease: etiology, pathogenesis and levodopa bioavailability
Parkinson ’s disease (PD), a neurodegenerative disorder with an unknown etiology, is primarily characterized by the degeneration of dopamine (DA) neurons. The prevalence of PD has experienced a significant surg... (Source: Immunity and Aging)
Source: Immunity and Aging - January 2, 2024 Category: Geriatrics Authors: Bang-rong Wei, Yu-jia Zhao, Yu-feng Cheng, Chun Huang and Feng Zhang Tags: Review Source Type: research
Partial loss of Sorting Nexin 27 resembles age- and Down syndrome-associated T cell dysfunctions
Sorting Nexin 27 (SNX27)-retromer complex facilitates cargo recycling from endosomes to the plasma membrane. SNX27 downregulation in neurons, as the result of Trisomy 21 (T21), has been linked with cognitive d... (Source: Immunity and Aging)
Source: Immunity and Aging - January 2, 2024 Category: Geriatrics Authors: Cristina Rodriguez-Rodriguez, Natalia Gonz ález-Mancha, Ane Ochoa-Echeverría, Rosa Liébana and Isabel Merida Tags: Research Source Type: research
An aging-related immune landscape in the hematopoietic immune system
Aging is a holistic change that has a major impact on the immune system, and immunosenescence contributes to the overall progression of aging. The bone marrow is the most important hematopoietic immune organ, ... (Source: Immunity and Aging)
Source: Immunity and Aging - January 2, 2024 Category: Geriatrics Authors: Jianjie Lv, Chun Zhang, Xiuxing Liu, Chenyang Gu, Yidan Liu, Yuehan Gao, Zhaohao Huang, Qi Jiang, Binyao Chen, Daquan He, Tianfu Wang, Zhuping Xu and Wenru Su Tags: Research Source Type: research
Blood circulating bacterial DNA in hospitalized old COVID-19 patients
Coronavirus disease COVID-19 is a heterogeneous condition caused by SARS-CoV-2 infection. Generally, it is characterized by interstitial pneumonia that can lead to impaired gas-exchange, acute respiratory fail... (Source: Immunity and Aging)
Source: Immunity and Aging - December 18, 2023 Category: Geriatrics Authors: Robertina Giacconi, Patrizia D ’Aquila, Maurizio Cardelli, Francesco Piacenza, Elisa Pierpaoli, Giada Sena, Mirko Di Rosa, Anna Rita Bonfigli, Roberta Galeazzi, Antonio Cherubini, Massimiliano Fedecostante, Riccardo Sarzani, Chiara Di Pentima, Piero Gio Tags: Research Source Type: research
The inter-link of ageing, cancer and immunity: findings from real-world retrospective study
Although the concept of declined immune function associated with cancer has been accepted extensively, real-world clinical studies focusing on analysis of the peripheral blood immune changes underlying ageing,... (Source: Immunity and Aging)
Source: Immunity and Aging - December 15, 2023 Category: Geriatrics Authors: Xiaomin Fu, Peng Qin, Fanghui Li, Huifang Zhu, Hongqin You, Yong Zhang, Benling Xu, Tiepeng Li, Fang Zhang, Lu Han, Lingdi Zhao, Baozhen Ma, Zibing Wang and Quanli Gao Tags: Research Source Type: research
IL-17A promotes the progression of Alzheimer ’s disease in APP/PS1 mice
Alzheimer ’s disease (AD), which is the most common cause of dementia in elderly individuals, is a progressive neurodegenerative disorder. Neuroinflammation, which is an immune response that is activated by gli... (Source: Immunity and Aging)
Source: Immunity and Aging - December 14, 2023 Category: Geriatrics Authors: Min Cao, Jing Liu, Xiaomin Zhang, Yaqi Wang, Yuli Hou, Qiao Song, Yuting Cui, Yue Zhao and Peichang Wang Tags: Research Source Type: research
