Partial loss of Sorting Nexin 27 resembles age- and Down syndrome-associated T cell dysfunctions
Sorting Nexin 27 (SNX27)-retromer complex facilitates cargo recycling from endosomes to the plasma membrane. SNX27 downregulation in neurons, as the result of Trisomy 21 (T21), has been linked with cognitive d...
Source: Immunity and Aging - Category: Geriatrics Authors: Cristina Rodriguez-Rodriguez, Natalia Gonz ález-Mancha, Ane Ochoa-Echeverría, Rosa Liébana and Isabel Merida Tags: Research Source Type: research