Genetic characterisation of the Connemara pony and the Warmblood horse using a within-breed clustering approach
CONCLUSIONS: Distinct genetic groups of individuals were revealed within each breed, and in WB these genetic groups reflected population substructure better than studbook or country of origin. Ontology terms associated with immune and inflammatory responses were identified from the signatures of selection between CP genetic groups, and while CP were less inbred than WB, the evidence pointed to a greater degree of recent inbreeding. The ratio of Neb to Ne was similar in CP and WB, indicating the influence of popular sires is similar in CP and WB.PMID:37592264 | PMC:PMC10436415 | DOI:10.1186/s12711-023-00827-w (Source: Genet Sel Evol)
Source: Genet Sel Evol - August 17, 2023 Category: Genetics & Stem Cells Authors: Victoria Lindsay-McGee Enrique Sanchez-Molano Georgios Banos Emily L Clark Richard J Piercy Androniki Psifidi Source Type: research
Genetic characterisation of the Connemara pony and the Warmblood horse using a within-breed clustering approach
CONCLUSIONS: Distinct genetic groups of individuals were revealed within each breed, and in WB these genetic groups reflected population substructure better than studbook or country of origin. Ontology terms associated with immune and inflammatory responses were identified from the signatures of selection between CP genetic groups, and while CP were less inbred than WB, the evidence pointed to a greater degree of recent inbreeding. The ratio of Neb to Ne was similar in CP and WB, indicating the influence of popular sires is similar in CP and WB.PMID:37592264 | PMC:PMC10436415 | DOI:10.1186/s12711-023-00827-w (Source: Genet Sel Evol)
Source: Genet Sel Evol - August 17, 2023 Category: Genetics & Stem Cells Authors: Victoria Lindsay-McGee Enrique Sanchez-Molano Georgios Banos Emily L Clark Richard J Piercy Androniki Psifidi Source Type: research
Genetic characterisation of the Connemara pony and the Warmblood horse using a within-breed clustering approach
CONCLUSIONS: Distinct genetic groups of individuals were revealed within each breed, and in WB these genetic groups reflected population substructure better than studbook or country of origin. Ontology terms associated with immune and inflammatory responses were identified from the signatures of selection between CP genetic groups, and while CP were less inbred than WB, the evidence pointed to a greater degree of recent inbreeding. The ratio of Neb to Ne was similar in CP and WB, indicating the influence of popular sires is similar in CP and WB.PMID:37592264 | PMC:PMC10436415 | DOI:10.1186/s12711-023-00827-w (Source: Genet Sel Evol)
Source: Genet Sel Evol - August 17, 2023 Category: Genetics & Stem Cells Authors: Victoria Lindsay-McGee Enrique Sanchez-Molano Georgios Banos Emily L Clark Richard J Piercy Androniki Psifidi Source Type: research
Genetic characterisation of the Connemara pony and the Warmblood horse using a within-breed clustering approach
CONCLUSIONS: Distinct genetic groups of individuals were revealed within each breed, and in WB these genetic groups reflected population substructure better than studbook or country of origin. Ontology terms associated with immune and inflammatory responses were identified from the signatures of selection between CP genetic groups, and while CP were less inbred than WB, the evidence pointed to a greater degree of recent inbreeding. The ratio of Neb to Ne was similar in CP and WB, indicating the influence of popular sires is similar in CP and WB.PMID:37592264 | PMC:PMC10436415 | DOI:10.1186/s12711-023-00827-w (Source: Genet Sel Evol)
Source: Genet Sel Evol - August 17, 2023 Category: Genetics & Stem Cells Authors: Victoria Lindsay-McGee Enrique Sanchez-Molano Georgios Banos Emily L Clark Richard J Piercy Androniki Psifidi Source Type: research
Genetic characterisation of the Connemara pony and the Warmblood horse using a within-breed clustering approach
CONCLUSIONS: Distinct genetic groups of individuals were revealed within each breed, and in WB these genetic groups reflected population substructure better than studbook or country of origin. Ontology terms associated with immune and inflammatory responses were identified from the signatures of selection between CP genetic groups, and while CP were less inbred than WB, the evidence pointed to a greater degree of recent inbreeding. The ratio of Neb to Ne was similar in CP and WB, indicating the influence of popular sires is similar in CP and WB.PMID:37592264 | PMC:PMC10436415 | DOI:10.1186/s12711-023-00827-w (Source: Genet Sel Evol)
Source: Genet Sel Evol - August 17, 2023 Category: Genetics & Stem Cells Authors: Victoria Lindsay-McGee Enrique Sanchez-Molano Georgios Banos Emily L Clark Richard J Piercy Androniki Psifidi Source Type: research
Genetic characterisation of the Connemara pony and the Warmblood horse using a within-breed clustering approach
CONCLUSIONS: Distinct genetic groups of individuals were revealed within each breed, and in WB these genetic groups reflected population substructure better than studbook or country of origin. Ontology terms associated with immune and inflammatory responses were identified from the signatures of selection between CP genetic groups, and while CP were less inbred than WB, the evidence pointed to a greater degree of recent inbreeding. The ratio of Neb to Ne was similar in CP and WB, indicating the influence of popular sires is similar in CP and WB.PMID:37592264 | PMC:PMC10436415 | DOI:10.1186/s12711-023-00827-w (Source: Genet Sel Evol)
Source: Genet Sel Evol - August 17, 2023 Category: Genetics & Stem Cells Authors: Victoria Lindsay-McGee Enrique Sanchez-Molano Georgios Banos Emily L Clark Richard J Piercy Androniki Psifidi Source Type: research
Genetic characterisation of the Connemara pony and the Warmblood horse using a within-breed clustering approach
CONCLUSIONS: Distinct genetic groups of individuals were revealed within each breed, and in WB these genetic groups reflected population substructure better than studbook or country of origin. Ontology terms associated with immune and inflammatory responses were identified from the signatures of selection between CP genetic groups, and while CP were less inbred than WB, the evidence pointed to a greater degree of recent inbreeding. The ratio of Neb to Ne was similar in CP and WB, indicating the influence of popular sires is similar in CP and WB.PMID:37592264 | PMC:PMC10436415 | DOI:10.1186/s12711-023-00827-w (Source: Genet Sel Evol)
Source: Genet Sel Evol - August 17, 2023 Category: Genetics & Stem Cells Authors: Victoria Lindsay-McGee Enrique Sanchez-Molano Georgios Banos Emily L Clark Richard J Piercy Androniki Psifidi Source Type: research
Genetic characterisation of the Connemara pony and the Warmblood horse using a within-breed clustering approach
CONCLUSIONS: Distinct genetic groups of individuals were revealed within each breed, and in WB these genetic groups reflected population substructure better than studbook or country of origin. Ontology terms associated with immune and inflammatory responses were identified from the signatures of selection between CP genetic groups, and while CP were less inbred than WB, the evidence pointed to a greater degree of recent inbreeding. The ratio of Neb to Ne was similar in CP and WB, indicating the influence of popular sires is similar in CP and WB.PMID:37592264 | DOI:10.1186/s12711-023-00827-w (Source: Genet Sel Evol)
Source: Genet Sel Evol - August 17, 2023 Category: Genetics & Stem Cells Authors: Victoria Lindsay-McGee Enrique Sanchez-Molano Georgios Banos Emily L Clark Richard J Piercy Androniki Psifidi Source Type: research
Potential of low-density genotype imputation for cost-efficient genomic selection for resistance to Flavobacterium columnare in rainbow trout (Oncorhynchus mykiss)
CONCLUSIONS: Compared to using the commercial HD panel, LD panels combined with imputation may provide a more affordable approach to genomic prediction of breeding values, which supports a more widespread adoption of genomic selection in aquaculture breeding programmes.PMID:37580697 | PMC:PMC10424455 | DOI:10.1186/s12711-023-00832-z (Source: Genet Sel Evol)
Source: Genet Sel Evol - August 14, 2023 Category: Genetics & Stem Cells Authors: Cl émence Fraslin Diego Robledo Antti Kause Ross D Houston Source Type: research
Potential of low-density genotype imputation for cost-efficient genomic selection for resistance to Flavobacterium columnare in rainbow trout (Oncorhynchus mykiss)
CONCLUSIONS: Compared to using the commercial HD panel, LD panels combined with imputation may provide a more affordable approach to genomic prediction of breeding values, which supports a more widespread adoption of genomic selection in aquaculture breeding programmes.PMID:37580697 | PMC:PMC10424455 | DOI:10.1186/s12711-023-00832-z (Source: Genet Sel Evol)
Source: Genet Sel Evol - August 14, 2023 Category: Genetics & Stem Cells Authors: Cl émence Fraslin Diego Robledo Antti Kause Ross D Houston Source Type: research
Potential of low-density genotype imputation for cost-efficient genomic selection for resistance to Flavobacterium columnare in rainbow trout (Oncorhynchus mykiss)
CONCLUSIONS: Compared to using the commercial HD panel, LD panels combined with imputation may provide a more affordable approach to genomic prediction of breeding values, which supports a more widespread adoption of genomic selection in aquaculture breeding programmes.PMID:37580697 | PMC:PMC10424455 | DOI:10.1186/s12711-023-00832-z (Source: Genet Sel Evol)
Source: Genet Sel Evol - August 14, 2023 Category: Genetics & Stem Cells Authors: Cl émence Fraslin Diego Robledo Antti Kause Ross D Houston Source Type: research
Using residual regressions to quantify and map signal leakage in genomic prediction
CONCLUSIONS: Residual single-marker regression analysis is a simple approach that can be used to detect regional genomic signals that are poorly captured by a model and to indicate ways to fix such problems.PMID:37550618 | PMC:PMC10405418 | DOI:10.1186/s12711-023-00830-1 (Source: Genet Sel Evol)
Source: Genet Sel Evol - August 7, 2023 Category: Genetics & Stem Cells Authors: Bruno D Valente Gustavo de Los Campos Alexander Grueneberg Ching-Yi Chen Roger Ros-Freixedes William O Herring Source Type: research
Estimation and consequences of direct-maternal genetic and environmental covariances in models for genetic evaluation in broilers
CONCLUSIONS: In this paper, we propose a simple approach to estimate the environmental direct-maternal covariance using standard software for REML analysis. The genetic covariance between dam and offspring was negative whereas the corresponding environmental covariance was positive. Considering both covariances in models for genetic evaluation increased the accuracy of predicted breeding values.PMID:37550635 | PMC:PMC10405509 | DOI:10.1186/s12711-023-00829-8 (Source: Genet Sel Evol)
Source: Genet Sel Evol - August 7, 2023 Category: Genetics & Stem Cells Authors: H élène Romé Thinh T Chu Danye Marois Chyong-Huoy Huang Per Madsen Just Jensen Source Type: research
Using residual regressions to quantify and map signal leakage in genomic prediction
CONCLUSIONS: Residual single-marker regression analysis is a simple approach that can be used to detect regional genomic signals that are poorly captured by a model and to indicate ways to fix such problems.PMID:37550618 | PMC:PMC10405418 | DOI:10.1186/s12711-023-00830-1 (Source: Genet Sel Evol)
Source: Genet Sel Evol - August 7, 2023 Category: Genetics & Stem Cells Authors: Bruno D Valente Gustavo de Los Campos Alexander Grueneberg Ching-Yi Chen Roger Ros-Freixedes William O Herring Source Type: research
Estimation and consequences of direct-maternal genetic and environmental covariances in models for genetic evaluation in broilers
CONCLUSIONS: In this paper, we propose a simple approach to estimate the environmental direct-maternal covariance using standard software for REML analysis. The genetic covariance between dam and offspring was negative whereas the corresponding environmental covariance was positive. Considering both covariances in models for genetic evaluation increased the accuracy of predicted breeding values.PMID:37550635 | PMC:PMC10405509 | DOI:10.1186/s12711-023-00829-8 (Source: Genet Sel Evol)
Source: Genet Sel Evol - August 7, 2023 Category: Genetics & Stem Cells Authors: H élène Romé Thinh T Chu Danye Marois Chyong-Huoy Huang Per Madsen Just Jensen Source Type: research
