Subtelomeres: hotspots of genome variation
Genes Genet Syst. 2023 Aug 30. doi: 10.1266/ggs.23-00049. Online ahead of print.ABSTRACTEukaryotic cells contain multiple types of duplicated sequences. Typical examples are tandem repeat sequences including telomeres, centromeres, rDNA genes and transposable elements. Most of these sequences are unstable; thus, their copy numbers or sequences change rapidly in the course of evolution. In this review, I will describe roles of subtelomere regions, which are located adjacent to telomeres at chromosome ends, and recent discoveries about their sequence variation.PMID:37648502 | DOI:10.1266/ggs.23-00049 (Source: Genes and Genetic Systems)
Source: Genes and Genetic Systems - August 30, 2023 Category: Genetics & Stem Cells Authors: Junko Kanoh Source Type: research
Subtelomeres: hotspots of genome variation
Genes Genet Syst. 2023 Aug 30. doi: 10.1266/ggs.23-00049. Online ahead of print.ABSTRACTEukaryotic cells contain multiple types of duplicated sequences. Typical examples are tandem repeat sequences including telomeres, centromeres, rDNA genes and transposable elements. Most of these sequences are unstable; thus, their copy numbers or sequences change rapidly in the course of evolution. In this review, I will describe roles of subtelomere regions, which are located adjacent to telomeres at chromosome ends, and recent discoveries about their sequence variation.PMID:37648502 | DOI:10.1266/ggs.23-00049 (Source: Genes and Genetic Systems)
Source: Genes and Genetic Systems - August 30, 2023 Category: Genetics & Stem Cells Authors: Junko Kanoh Source Type: research
Subtelomeres: hotspots of genome variation
Genes Genet Syst. 2023 Aug 30. doi: 10.1266/ggs.23-00049. Online ahead of print.ABSTRACTEukaryotic cells contain multiple types of duplicated sequences. Typical examples are tandem repeat sequences including telomeres, centromeres, rDNA genes and transposable elements. Most of these sequences are unstable; thus, their copy numbers or sequences change rapidly in the course of evolution. In this review, I will describe roles of subtelomere regions, which are located adjacent to telomeres at chromosome ends, and recent discoveries about their sequence variation.PMID:37648502 | DOI:10.1266/ggs.23-00049 (Source: Genes and Genetic Systems)
Source: Genes and Genetic Systems - August 30, 2023 Category: Genetics & Stem Cells Authors: Junko Kanoh Source Type: research
Genealogical characterization of regional populations and dorsal coat color variation in the house mouse Mus musculus from Asia based on haplotype structure analysis of a gene-rich region harboring Mc1r
Genes Genet Syst. 2023 Aug 8. doi: 10.1266/ggs.22-00157. Online ahead of print.ABSTRACTWe analyzed 196 haplotype sequences from a gene-rich region (250 kb) that includes Mc1r, a gene involved in coat color regulation, to gain insight into the evolution of coat color variation in subspecies of the house mouse Mus musculus. Phylogenetic networks revealed haplotype groups from the major subspecies of M. m. castaneus (CAS), M. m. domesticus (DOM), and M. m. musculus (MUS). Using haplotype sequences assigned to each of CAS and MUS through phylogenetic analysis, we proposed migration routes associated with prehistoric humans fro...
Source: Genes and Genetic Systems - August 9, 2023 Category: Genetics & Stem Cells Authors: Kazuhiro Zakoh Kazumichi Fujiwara Toyoyuki Takada Naoki Osada Hitoshi Suzuki Source Type: research
Genealogical characterization of regional populations and dorsal coat color variation in the house mouse Mus musculus from Asia based on haplotype structure analysis of a gene-rich region harboring Mc1r
Genes Genet Syst. 2023 Aug 8. doi: 10.1266/ggs.22-00157. Online ahead of print.ABSTRACTWe analyzed 196 haplotype sequences from a gene-rich region (250 kb) that includes Mc1r, a gene involved in coat color regulation, to gain insight into the evolution of coat color variation in subspecies of the house mouse Mus musculus. Phylogenetic networks revealed haplotype groups from the major subspecies of M. m. castaneus (CAS), M. m. domesticus (DOM), and M. m. musculus (MUS). Using haplotype sequences assigned to each of CAS and MUS through phylogenetic analysis, we proposed migration routes associated with prehistoric humans fro...
Source: Genes and Genetic Systems - August 9, 2023 Category: Genetics & Stem Cells Authors: Kazuhiro Zakoh Kazumichi Fujiwara Toyoyuki Takada Naoki Osada Hitoshi Suzuki Source Type: research
Genealogical characterization of regional populations and dorsal coat color variation in the house mouse Mus musculus from Asia based on haplotype structure analysis of a gene-rich region harboring Mc1r
Genes Genet Syst. 2023 Aug 8. doi: 10.1266/ggs.22-00157. Online ahead of print.ABSTRACTWe analyzed 196 haplotype sequences from a gene-rich region (250 kb) that includes Mc1r, a gene involved in coat color regulation, to gain insight into the evolution of coat color variation in subspecies of the house mouse Mus musculus. Phylogenetic networks revealed haplotype groups from the major subspecies of M. m. castaneus (CAS), M. m. domesticus (DOM), and M. m. musculus (MUS). Using haplotype sequences assigned to each of CAS and MUS through phylogenetic analysis, we proposed migration routes associated with prehistoric humans fro...
Source: Genes and Genetic Systems - August 9, 2023 Category: Genetics & Stem Cells Authors: Kazuhiro Zakoh Kazumichi Fujiwara Toyoyuki Takada Naoki Osada Hitoshi Suzuki Source Type: research
Genealogical characterization of regional populations and dorsal coat color variation in the house mouse Mus musculus from Asia based on haplotype structure analysis of a gene-rich region harboring Mc1r
Genes Genet Syst. 2023 Aug 8. doi: 10.1266/ggs.22-00157. Online ahead of print.ABSTRACTWe analyzed 196 haplotype sequences from a gene-rich region (250 kb) that includes Mc1r, a gene involved in coat color regulation, to gain insight into the evolution of coat color variation in subspecies of the house mouse Mus musculus. Phylogenetic networks revealed haplotype groups from the major subspecies of M. m. castaneus (CAS), M. m. domesticus (DOM), and M. m. musculus (MUS). Using haplotype sequences assigned to each of CAS and MUS through phylogenetic analysis, we proposed migration routes associated with prehistoric humans fro...
Source: Genes and Genetic Systems - August 9, 2023 Category: Genetics & Stem Cells Authors: Kazuhiro Zakoh Kazumichi Fujiwara Toyoyuki Takada Naoki Osada Hitoshi Suzuki Source Type: research
Genealogical characterization of regional populations and dorsal coat color variation in the house mouse Mus musculus from Asia based on haplotype structure analysis of a gene-rich region harboring Mc1r
Genes Genet Syst. 2023 Aug 8. doi: 10.1266/ggs.22-00157. Online ahead of print.ABSTRACTWe analyzed 196 haplotype sequences from a gene-rich region (250 kb) that includes Mc1r, a gene involved in coat color regulation, to gain insight into the evolution of coat color variation in subspecies of the house mouse Mus musculus. Phylogenetic networks revealed haplotype groups from the major subspecies of M. m. castaneus (CAS), M. m. domesticus (DOM), and M. m. musculus (MUS). Using haplotype sequences assigned to each of CAS and MUS through phylogenetic analysis, we proposed migration routes associated with prehistoric humans fro...
Source: Genes and Genetic Systems - August 9, 2023 Category: Genetics & Stem Cells Authors: Kazuhiro Zakoh Kazumichi Fujiwara Toyoyuki Takada Naoki Osada Hitoshi Suzuki Source Type: research
Genealogical characterization of regional populations and dorsal coat color variation in the house mouse Mus musculus from Asia based on haplotype structure analysis of a gene-rich region harboring Mc1r
Genes Genet Syst. 2023 Aug 8. doi: 10.1266/ggs.22-00157. Online ahead of print.ABSTRACTWe analyzed 196 haplotype sequences from a gene-rich region (250 kb) that includes Mc1r, a gene involved in coat color regulation, to gain insight into the evolution of coat color variation in subspecies of the house mouse Mus musculus. Phylogenetic networks revealed haplotype groups from the major subspecies of M. m. castaneus (CAS), M. m. domesticus (DOM), and M. m. musculus (MUS). Using haplotype sequences assigned to each of CAS and MUS through phylogenetic analysis, we proposed migration routes associated with prehistoric humans fro...
Source: Genes and Genetic Systems - August 9, 2023 Category: Genetics & Stem Cells Authors: Kazuhiro Zakoh Kazumichi Fujiwara Toyoyuki Takada Naoki Osada Hitoshi Suzuki Source Type: research
Genealogical characterization of regional populations and dorsal coat color variation in the house mouse Mus musculus from Asia based on haplotype structure analysis of a gene-rich region harboring Mc1r
Genes Genet Syst. 2023 Aug 8. doi: 10.1266/ggs.22-00157. Online ahead of print.ABSTRACTWe analyzed 196 haplotype sequences from a gene-rich region (250 kb) that includes Mc1r, a gene involved in coat color regulation, to gain insight into the evolution of coat color variation in subspecies of the house mouse Mus musculus. Phylogenetic networks revealed haplotype groups from the major subspecies of M. m. castaneus (CAS), M. m. domesticus (DOM), and M. m. musculus (MUS). Using haplotype sequences assigned to each of CAS and MUS through phylogenetic analysis, we proposed migration routes associated with prehistoric humans fro...
Source: Genes and Genetic Systems - August 9, 2023 Category: Genetics & Stem Cells Authors: Kazuhiro Zakoh Kazumichi Fujiwara Toyoyuki Takada Naoki Osada Hitoshi Suzuki Source Type: research
Genealogical characterization of regional populations and dorsal coat color variation in the house mouse Mus musculus from Asia based on haplotype structure analysis of a gene-rich region harboring Mc1r
Genes Genet Syst. 2023 Aug 8. doi: 10.1266/ggs.22-00157. Online ahead of print.ABSTRACTWe analyzed 196 haplotype sequences from a gene-rich region (250 kb) that includes Mc1r, a gene involved in coat color regulation, to gain insight into the evolution of coat color variation in subspecies of the house mouse Mus musculus. Phylogenetic networks revealed haplotype groups from the major subspecies of M. m. castaneus (CAS), M. m. domesticus (DOM), and M. m. musculus (MUS). Using haplotype sequences assigned to each of CAS and MUS through phylogenetic analysis, we proposed migration routes associated with prehistoric humans fro...
Source: Genes and Genetic Systems - August 9, 2023 Category: Genetics & Stem Cells Authors: Kazuhiro Zakoh Kazumichi Fujiwara Toyoyuki Takada Naoki Osada Hitoshi Suzuki Source Type: research
Genealogical characterization of regional populations and dorsal coat color variation in the house mouse Mus musculus from Asia based on haplotype structure analysis of a gene-rich region harboring Mc1r
Genes Genet Syst. 2023 Aug 8. doi: 10.1266/ggs.22-00157. Online ahead of print.ABSTRACTWe analyzed 196 haplotype sequences from a gene-rich region (250 kb) that includes Mc1r, a gene involved in coat color regulation, to gain insight into the evolution of coat color variation in subspecies of the house mouse Mus musculus. Phylogenetic networks revealed haplotype groups from the major subspecies of M. m. castaneus (CAS), M. m. domesticus (DOM), and M. m. musculus (MUS). Using haplotype sequences assigned to each of CAS and MUS through phylogenetic analysis, we proposed migration routes associated with prehistoric humans fro...
Source: Genes and Genetic Systems - August 9, 2023 Category: Genetics & Stem Cells Authors: Kazuhiro Zakoh Kazumichi Fujiwara Toyoyuki Takada Naoki Osada Hitoshi Suzuki Source Type: research
Genealogical characterization of regional populations and dorsal coat color variation in the house mouse Mus musculus from Asia based on haplotype structure analysis of a gene-rich region harboring Mc1r
Genes Genet Syst. 2023 Aug 8. doi: 10.1266/ggs.22-00157. Online ahead of print.ABSTRACTWe analyzed 196 haplotype sequences from a gene-rich region (250 kb) that includes Mc1r, a gene involved in coat color regulation, to gain insight into the evolution of coat color variation in subspecies of the house mouse Mus musculus. Phylogenetic networks revealed haplotype groups from the major subspecies of M. m. castaneus (CAS), M. m. domesticus (DOM), and M. m. musculus (MUS). Using haplotype sequences assigned to each of CAS and MUS through phylogenetic analysis, we proposed migration routes associated with prehistoric humans fro...
Source: Genes and Genetic Systems - August 9, 2023 Category: Genetics & Stem Cells Authors: Kazuhiro Zakoh Kazumichi Fujiwara Toyoyuki Takada Naoki Osada Hitoshi Suzuki Source Type: research
Genealogical characterization of regional populations and dorsal coat color variation in the house mouse Mus musculus from Asia based on haplotype structure analysis of a gene-rich region harboring Mc1r
Genes Genet Syst. 2023 Aug 8. doi: 10.1266/ggs.22-00157. Online ahead of print.ABSTRACTWe analyzed 196 haplotype sequences from a gene-rich region (250 kb) that includes Mc1r, a gene involved in coat color regulation, to gain insight into the evolution of coat color variation in subspecies of the house mouse Mus musculus. Phylogenetic networks revealed haplotype groups from the major subspecies of M. m. castaneus (CAS), M. m. domesticus (DOM), and M. m. musculus (MUS). Using haplotype sequences assigned to each of CAS and MUS through phylogenetic analysis, we proposed migration routes associated with prehistoric humans fro...
Source: Genes and Genetic Systems - August 9, 2023 Category: Genetics & Stem Cells Authors: Kazuhiro Zakoh Kazumichi Fujiwara Toyoyuki Takada Naoki Osada Hitoshi Suzuki Source Type: research
Genealogical characterization of regional populations and dorsal coat color variation in the house mouse Mus musculus from Asia based on haplotype structure analysis of a gene-rich region harboring Mc1r
Genes Genet Syst. 2023 Aug 8. doi: 10.1266/ggs.22-00157. Online ahead of print.ABSTRACTWe analyzed 196 haplotype sequences from a gene-rich region (250 kb) that includes Mc1r, a gene involved in coat color regulation, to gain insight into the evolution of coat color variation in subspecies of the house mouse Mus musculus. Phylogenetic networks revealed haplotype groups from the major subspecies of M. m. castaneus (CAS), M. m. domesticus (DOM), and M. m. musculus (MUS). Using haplotype sequences assigned to each of CAS and MUS through phylogenetic analysis, we proposed migration routes associated with prehistoric humans fro...
Source: Genes and Genetic Systems - August 9, 2023 Category: Genetics & Stem Cells Authors: Kazuhiro Zakoh Kazumichi Fujiwara Toyoyuki Takada Naoki Osada Hitoshi Suzuki Source Type: research
