Expression profiles in knock-down transgenic plants of high and low diversified duplicate genes in Arabidopsis thaliana
Genes Genet Syst. 2023 Sep 29. doi: 10.1266/ggs.23-00019. Online ahead of print.ABSTRACTDuplicated genes show various degrees of functional diversification in plants. We previously identified 1,052 pairs of high diversified duplicates (HDDs) and 600 pairs of low diversified duplicates (LDDs) in Arabidopsis thaliana. Single knock-down of HDDs induced abnormal phenotypic changes because the other gene copy could not compensate for the knock-down effect, while single knock-down of LDDs did not induce abnormal phenotypic changes because of functional compensation by the copy gene. Here, focusing on one pair each of HDDs and LD...
Source: Genes and Genetic Systems - October 1, 2023 Category: Genetics & Stem Cells Authors: Tomoyuki Takeda Akihiro Ezoe Kousuke Hanada Source Type: research
Mechanisms and impacts of genomic changes that are mediated by repetitive sequences in eukaryotes
Genes Genet Syst. 2023;98(3):101. doi: 10.1266/ggs.98.101.NO ABSTRACTPMID:37779087 | DOI:10.1266/ggs.98.101 (Source: Genes and Genetic Systems)
Source: Genes and Genetic Systems - October 1, 2023 Category: Genetics & Stem Cells Authors: Mariko Sasaki Source Type: research
Testing immediate dosage compensation in Drosophila miranda via irradiation with heavy-ion beams
In this study, by irradiating Drosophila miranda male flies, which carry young sex chromosomes (the so-called neo-sex chromosomes), with heavy-ion beams, we induced deletions in the neo-Y chromosome to mimic the condition of Y-chromosome degeneration, in which functional neo-Y-linked genes are nonfunctionalized; furthermore, we tested whether their neo-X-linked gametologs were immediately upregulated. Because the males that received 2-Gy iron-ion beam irradiation exhibited lower fertility, we sequenced the genomes and transcriptomes of six F1 males derived from these males. Our pipeline identified 82 neo-Y-linked genes in ...
Source: Genes and Genetic Systems - October 1, 2023 Category: Genetics & Stem Cells Authors: Masafumi Ogawa Kazuhide Tsuneizumi Tomoko Abe Masafumi Nozawa Source Type: research
Expression profiles in knock-down transgenic plants of high and low diversified duplicate genes in Arabidopsis thaliana
Genes Genet Syst. 2023 Sep 29. doi: 10.1266/ggs.23-00019. Online ahead of print.ABSTRACTDuplicated genes show various degrees of functional diversification in plants. We previously identified 1,052 pairs of high diversified duplicates (HDDs) and 600 pairs of low diversified duplicates (LDDs) in Arabidopsis thaliana. Single knock-down of HDDs induced abnormal phenotypic changes because the other gene copy could not compensate for the knock-down effect, while single knock-down of LDDs did not induce abnormal phenotypic changes because of functional compensation by the copy gene. Here, focusing on one pair each of HDDs and LD...
Source: Genes and Genetic Systems - October 1, 2023 Category: Genetics & Stem Cells Authors: Tomoyuki Takeda Akihiro Ezoe Kousuke Hanada Source Type: research
Mechanisms and impacts of genomic changes that are mediated by repetitive sequences in eukaryotes
Genes Genet Syst. 2023;98(3):101. doi: 10.1266/ggs.98.101.NO ABSTRACTPMID:37779087 | DOI:10.1266/ggs.98.101 (Source: Genes and Genetic Systems)
Source: Genes and Genetic Systems - October 1, 2023 Category: Genetics & Stem Cells Authors: Mariko Sasaki Source Type: research
Testing immediate dosage compensation in Drosophila miranda via irradiation with heavy-ion beams
In this study, by irradiating Drosophila miranda male flies, which carry young sex chromosomes (the so-called neo-sex chromosomes), with heavy-ion beams, we induced deletions in the neo-Y chromosome to mimic the condition of Y-chromosome degeneration, in which functional neo-Y-linked genes are nonfunctionalized; furthermore, we tested whether their neo-X-linked gametologs were immediately upregulated. Because the males that received 2-Gy iron-ion beam irradiation exhibited lower fertility, we sequenced the genomes and transcriptomes of six F1 males derived from these males. Our pipeline identified 82 neo-Y-linked genes in ...
Source: Genes and Genetic Systems - October 1, 2023 Category: Genetics & Stem Cells Authors: Masafumi Ogawa Kazuhide Tsuneizumi Tomoko Abe Masafumi Nozawa Source Type: research
Expression profiles in knock-down transgenic plants of high and low diversified duplicate genes in Arabidopsis thaliana
Genes Genet Syst. 2023 Sep 29. doi: 10.1266/ggs.23-00019. Online ahead of print.ABSTRACTDuplicated genes show various degrees of functional diversification in plants. We previously identified 1,052 pairs of high diversified duplicates (HDDs) and 600 pairs of low diversified duplicates (LDDs) in Arabidopsis thaliana. Single knock-down of HDDs induced abnormal phenotypic changes because the other gene copy could not compensate for the knock-down effect, while single knock-down of LDDs did not induce abnormal phenotypic changes because of functional compensation by the copy gene. Here, focusing on one pair each of HDDs and LD...
Source: Genes and Genetic Systems - October 1, 2023 Category: Genetics & Stem Cells Authors: Tomoyuki Takeda Akihiro Ezoe Kousuke Hanada Source Type: research
Mechanisms and impacts of genomic changes that are mediated by repetitive sequences in eukaryotes
Genes Genet Syst. 2023;98(3):101. doi: 10.1266/ggs.98.101.NO ABSTRACTPMID:37779087 | DOI:10.1266/ggs.98.101 (Source: Genes and Genetic Systems)
Source: Genes and Genetic Systems - October 1, 2023 Category: Genetics & Stem Cells Authors: Mariko Sasaki Source Type: research
Development and characterization of expressed sequence tag-simple sequence repeat markers for Anaphalis margaritacea var. yedoensis (Asteraceae)
Genes Genet Syst. 2023 Sep 26. doi: 10.1266/ggs.23-00037. Online ahead of print.ABSTRACTRNA-sequencing was used to develop 16 microsatellite markers for the pearly everlasting, Anaphalis margaritacea var. yedoensis (Franch. et Sav.) Ohwi (Asteraceae), which inhabits gravel bars throughout the Japanese archipelago. The mean number of alleles for these 16 markers in two populations in the Hokkaido and Shizuoka Prefectures, was 3.5 and 4.0, respectively, while the mean expected heterozygosity was 0.525 and 0.560, respectively, with a significant genetic differentiation between the two populations. All markers could also be am...
Source: Genes and Genetic Systems - September 28, 2023 Category: Genetics & Stem Cells Authors: Taishi Hoson Shoki Murakami Takuro Ito Masuyuki Maki Source Type: research
Development and characterization of expressed sequence tag-simple sequence repeat markers for Anaphalis margaritacea var. yedoensis (Asteraceae)
Genes Genet Syst. 2023 Sep 26. doi: 10.1266/ggs.23-00037. Online ahead of print.ABSTRACTRNA-sequencing was used to develop 16 microsatellite markers for the pearly everlasting, Anaphalis margaritacea var. yedoensis (Franch. et Sav.) Ohwi (Asteraceae), which inhabits gravel bars throughout the Japanese archipelago. The mean number of alleles for these 16 markers in two populations in the Hokkaido and Shizuoka Prefectures, was 3.5 and 4.0, respectively, while the mean expected heterozygosity was 0.525 and 0.560, respectively, with a significant genetic differentiation between the two populations. All markers could also be am...
Source: Genes and Genetic Systems - September 28, 2023 Category: Genetics & Stem Cells Authors: Taishi Hoson Shoki Murakami Takuro Ito Masuyuki Maki Source Type: research
Development and characterization of expressed sequence tag-simple sequence repeat markers for Anaphalis margaritacea var. yedoensis (Asteraceae)
Genes Genet Syst. 2023 Sep 26. doi: 10.1266/ggs.23-00037. Online ahead of print.ABSTRACTRNA-sequencing was used to develop 16 microsatellite markers for the pearly everlasting, Anaphalis margaritacea var. yedoensis (Franch. et Sav.) Ohwi (Asteraceae), which inhabits gravel bars throughout the Japanese archipelago. The mean number of alleles for these 16 markers in two populations in the Hokkaido and Shizuoka Prefectures, was 3.5 and 4.0, respectively, while the mean expected heterozygosity was 0.525 and 0.560, respectively, with a significant genetic differentiation between the two populations. All markers could also be am...
Source: Genes and Genetic Systems - September 28, 2023 Category: Genetics & Stem Cells Authors: Taishi Hoson Shoki Murakami Takuro Ito Masuyuki Maki Source Type: research
A new variant of the ectodysplasin A receptor death domain gene associated with anhidrotic ectodermal dysplasia in a Turkish family and its simple diagnosis by restriction fragment length polymorphism
Genes Genet Syst. 2023 Sep 7. doi: 10.1266/ggs.22-00138. Online ahead of print.ABSTRACTEctodermal dysplasia (ED), which exhibits a wide range of clinical symptoms, may be classified into three major types: hypohidrotic, anhidrotic, and hidrotic. A male child (proband) showing anhidrotic dysplasia was used as the subject of this study. The biopsy of the big toe revealed that the male child had no sweat glands. Genetic analysis of the patient revealed a mutation caused by a homozygous nucleotide substitution in the EDAR-associated death domain (EDARADD) (rs114632254) gene c.439G>A (p.Gly147Arg). Phenotypically, his teeth ...
Source: Genes and Genetic Systems - September 6, 2023 Category: Genetics & Stem Cells Authors: Eyyup Rencuzogullari Banu Guven Ezer Source Type: research
A new variant of the ectodysplasin A receptor death domain gene associated with anhidrotic ectodermal dysplasia in a Turkish family and its simple diagnosis by restriction fragment length polymorphism
Genes Genet Syst. 2023 Sep 7. doi: 10.1266/ggs.22-00138. Online ahead of print.ABSTRACTEctodermal dysplasia (ED), which exhibits a wide range of clinical symptoms, may be classified into three major types: hypohidrotic, anhidrotic, and hidrotic. A male child (proband) showing anhidrotic dysplasia was used as the subject of this study. The biopsy of the big toe revealed that the male child had no sweat glands. Genetic analysis of the patient revealed a mutation caused by a homozygous nucleotide substitution in the EDAR-associated death domain (EDARADD) (rs114632254) gene c.439G>A (p.Gly147Arg). Phenotypically, his teeth ...
Source: Genes and Genetic Systems - September 6, 2023 Category: Genetics & Stem Cells Authors: Eyyup Rencuzogullari Banu Guven Ezer Source Type: research
A new variant of the ectodysplasin A receptor death domain gene associated with anhidrotic ectodermal dysplasia in a Turkish family and its simple diagnosis by restriction fragment length polymorphism
Genes Genet Syst. 2023 Sep 7. doi: 10.1266/ggs.22-00138. Online ahead of print.ABSTRACTEctodermal dysplasia (ED), which exhibits a wide range of clinical symptoms, may be classified into three major types: hypohidrotic, anhidrotic, and hidrotic. A male child (proband) showing anhidrotic dysplasia was used as the subject of this study. The biopsy of the big toe revealed that the male child had no sweat glands. Genetic analysis of the patient revealed a mutation caused by a homozygous nucleotide substitution in the EDAR-associated death domain (EDARADD) (rs114632254) gene c.439G>A (p.Gly147Arg). Phenotypically, his teeth ...
Source: Genes and Genetic Systems - September 6, 2023 Category: Genetics & Stem Cells Authors: Eyyup Rencuzogullari Banu Guven Ezer Source Type: research
A new variant of the ectodysplasin A receptor death domain gene associated with anhidrotic ectodermal dysplasia in a Turkish family and its simple diagnosis by restriction fragment length polymorphism
Genes Genet Syst. 2023 Sep 7. doi: 10.1266/ggs.22-00138. Online ahead of print.ABSTRACTEctodermal dysplasia (ED), which exhibits a wide range of clinical symptoms, may be classified into three major types: hypohidrotic, anhidrotic, and hidrotic. A male child (proband) showing anhidrotic dysplasia was used as the subject of this study. The biopsy of the big toe revealed that the male child had no sweat glands. Genetic analysis of the patient revealed a mutation caused by a homozygous nucleotide substitution in the EDAR-associated death domain (EDARADD) (rs114632254) gene c.439G>A (p.Gly147Arg). Phenotypically, his teeth ...
Source: Genes and Genetic Systems - September 6, 2023 Category: Genetics & Stem Cells Authors: Eyyup Rencuzogullari Banu Guven Ezer Source Type: research
