General and Comparative Endocrinology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

The chondrichthyan glucagon-like peptide 3 regulates hepatic ketone metabolism in the Pacific spiny dogfish Squalus suckleyi
Gen Comp Endocrinol. 2024 Feb 10;350:114470. doi: 10.1016/j.ygcen.2024.114470. Online ahead of print.ABSTRACTChondrichthyans have a novel proglucagon-derived peptide, glucagon-like peptide (GLP)-3, in addition to GLP-1 and GLP-2 that occur in other vertebrates. Given that the GLPs are important regulators of metabolic homeostasis across vertebrates, we sought to investigate whether GLP-3 displays functional actions on metabolism within a representative chondrichthyan, the Pacific spiny dogfish Squalus suckleyi. There were no observed effects of GLP-3 perfusion (10 nM for 15 min) on the rate of glucose or oleic acid acquisi...
Source: General and Comparative Endocrinology - February 12, 2024 Category: Endocrinology Authors: Alyssa M Weinrauch Ian A Bouyoucos J Michael Conlon W Gary Anderson Source Type: research

The chondrichthyan glucagon-like peptide 3 regulates hepatic ketone metabolism in the Pacific spiny dogfish Squalus suckleyi
Gen Comp Endocrinol. 2024 Feb 10:114470. doi: 10.1016/j.ygcen.2024.114470. Online ahead of print.ABSTRACTChondrichthyans have a novel proglucagon-derived peptide, glucagon-like peptide (GLP)-3, in addition to GLP-1 and GLP-2 that occur in other vertebrates. Given that the GLPs are important regulators of metabolic homeostasis across vertebrates, we sought to investigate whether GLP-3 displays functional actions on metabolism within a representative chondrichthyan, the Pacific spiny dogfish Squalus suckleyi. There were no observed effects of GLP-3 perfusion (10 nM for 15 min) on the rate of glucose or oleic acid acquisition...
Source: General and Comparative Endocrinology - February 12, 2024 Category: Endocrinology Authors: Alyssa M Weinrauch Ian A Bouyoucos J Michael Conlon W Gary Anderson Source Type: research

Coping with extreme free cortisol levels: Seasonal stress axis changes in sympatric North American flying squirrels
Gen Comp Endocrinol. 2024 Feb 9;349:114467. doi: 10.1016/j.ygcen.2024.114467. Online ahead of print.ABSTRACTMost environments exhibit predictable yearly changes, permitting animals to anticipate them. The hypothalamic-pituitary-adrenal (HPA) axis is a key physiological pathway that enables animals to cope with such changes. Monitoring glucocorticoid (the end products of the HPA axis) levels in wild animals throughout the year can improve our understanding of how this pathway responds to different conditions. For this study, we collected 18 months of data on two species of North American flying squirrels (Glaucomys sabrinus...
Source: General and Comparative Endocrinology - February 11, 2024 Category: Endocrinology Authors: Samantha M Stead Phoebe D Edwards Rebekah Persad Rudy Boonstra Julie A Teichroeb Rupert Palme Jeff Bowman Source Type: research

Gonadotropin expression, pituitary and plasma levels in the reproductive cycle of wild and captive-reared greater amberjack (Seriola dumerili)
Gen Comp Endocrinol. 2024 Feb 7:114465. doi: 10.1016/j.ygcen.2024.114465. Online ahead of print.ABSTRACTWe compared the endocrine status of the pituitary-gonad axis of wild and captive-reared greater amberjack (Seriola dumerili) during the reproductive cycle (April - July), reporting on the expression and release of the two gonadotropins for the first time in the Mediterranean Sea. Ovaries from wild females were characterized histologically as DEVELOPING in early May and SPAWNING capable in late May-July, the latter having a 3 to 4-fold higher gonadosomatic index (GSI). SPAWNING capable wild females exhibited an increase i...
Source: General and Comparative Endocrinology - February 9, 2024 Category: Endocrinology Authors: Ioannis Fakriadis Iris Meiri-Ashkenazi Chen Bracha Hanna Rosenfeld Aldo Corriero Rosa Zupa Chrysovalentinos Pousis Maria Papadaki Constantinos C Mylonas Source Type: research

α1 and β3 adrenergic receptor-mediated excitatory effects of adrenaline on the caudal neurosecretory system (CNSS) in olive flounder, Paralichthys olivaceus
In this study, we investigated the modulatory role of adrenaline and adrenergic receptors on the neuroendocrine Dahlgren cells in the caudal neurosecretory system (CNSS) of olive flounder. Ex vivo electrophysiological recordings revealed that adrenaline significantly increased the firing frequency and altered the firing pattern of Dahlgren cells. Moreover, treatment with adrenaline led to a significant upregulation of ion channels and major hormone secretion genes in CNSS at the mRNA levels. Additionally, treatment with adrenaline resulted in a significantly elevation in the expression levels of α1- and β3-adrenergic rec...
Source: General and Comparative Endocrinology - February 7, 2024 Category: Endocrinology Authors: Mengmeng Shi Cheng Liu Yeyang Qin Lin Yv Weiqun Lu Source Type: research

Adiponectin and visfatin expression profile in extra-embryonic annexes and role during embryo development in layer and broiler chickens
Gen Comp Endocrinol. 2024 Feb 5:114466. doi: 10.1016/j.ygcen.2024.114466. Online ahead of print.ABSTRACTSome evidence showed differences between layer and broiler embryo development. We recently showed that two adipokines, adiponectin and visfatin are expressed in the extra embryonic membranes and fluids. However, their role in the embryo development is unknown. Thus, our objectives were 1. to compare the expression of AdipoQ and its receptors AdipoR1 and AdipoR2 and visfatin in extra-embryonic annexes in broiler and layer breeders during the embryo development and 2. to investigate the role of two adipokines in embryo dev...
Source: General and Comparative Endocrinology - February 7, 2024 Category: Endocrinology Authors: Oph élie Bernardi Christelle Ram é Maxime Reverchon Jo ëlle Dupont Source Type: research

Characterization of insulin-like growth factor 3 and its potential role in the spotted steed Hemibarbus maculatus ovary development
Gen Comp Endocrinol. 2024 Feb 3;349:114464. doi: 10.1016/j.ygcen.2024.114464. Online ahead of print.ABSTRACTAs a new member of the insulin-like growth factors (Igfs), Igf3 was reported to play a vital role in fish reproduction. However, in spotted steed, the function of Igf3 remains largely unknown. In the present study, we identified and characterized Igf3 gene in spotted steed. Structural analysis showed that Igf3 contained five domains (B, C, A, D, E) and six conserved cysteine residues. The expression of Igf3 mRNA and protein were increased during ovary development and peaked in the maturation stage. The subcellular lo...
Source: General and Comparative Endocrinology - February 5, 2024 Category: Endocrinology Authors: Huifen Liu Qi Guo Xinyu Wang Xiao Ma Xuejun Li Xue Tian Source Type: research

Zebrafish prss59.1 is involved in chorion development
In this study, we established a prss59.1 gene knockout strain using the CRISPR/Cas9 system. Phenotypic analysis of prss59.1 knockout fish showed that prss59.1 is associated with chorion elevation, a prominent event in egg activation during fertilization. The chorions of heterozygous and homozygous prss59.1 mutant zebrafish were smaller than those of the wild type. The results suggested that Prss59.1 is necessary for chorion expansion. The homozygous prss59.1 mutant strain, with a small chorion, showed an extremely low survival rate. Fiber-supported knob-like structures (KS) on the chorion showed an abnormal structure in pr...
Source: General and Comparative Endocrinology - January 28, 2024 Category: Endocrinology Authors: Md Rezanujjaman Theeranukul Pachoensuk Md Forhad Hossain Md Maisum Sarwar Jyoti Md Rubel Rana Eisei Tsutsumi Takumi Mouri Maria Bramastri Susilo Klangnurak Wanlada Chihiro Yamamoto Md Hasan Ali Toshinobu Tokumoto Source Type: research

Investigations of the function of AMH in granulosa cells in hens
Gen Comp Endocrinol. 2024 Jan 22;349:114454. doi: 10.1016/j.ygcen.2024.114454. Online ahead of print.ABSTRACTAnti-mullerian hormone (AMH) plays a crucial role in follicle regulation in mammals by preventing premature primordial follicle activation and restricting follicle development through reduction of FSH sensitivity and inhibition of FSH-induced increase of steroidogenic enzymes. AMH is produced by granulosa cells from growing follicles and expression declines at the time of selection in both mammalian and avian species. The role of AMH in chicken granulosa cells remains unclear, as research is complicated because mamm...
Source: General and Comparative Endocrinology - January 24, 2024 Category: Endocrinology Authors: Laurie Francoeur Deena M Scoville Patricia A Johnson Source Type: research

Resistin in endocrine pancreas of sheep: Presence and expression related to different diets
This study aims to evaluate the presence and expression of RETN in the pancreas of 15 adult female sheep reared on Apennine pastures, which show a decrease in their nutritional value due to the drought stress linked to the increasing summer aridity. The sheep were divided into 3 groups according to the diet they were subjected to: maximum pasture flowering (MxF) group, maximum pasture dryness (MxD) group, and experimental (Exp) group which received a feed supplementation in addition to the MxD group feeding. Immunohistochemistry and immunofluorescence were performed on formalin-fixed and paraffin-embedded sections of the p...
Source: General and Comparative Endocrinology - January 21, 2024 Category: Endocrinology Authors: Margherita Maranesi Elisa Palmioli Cecilia Dall'Aglio Daniele Marini Polina Anipchenko Elena De Felice Paola Scocco Francesca Mercati Source Type: research

Heterogeneity in the preferential diet of neotropical bats impacts the pancreatic islet mass and α and β cell distribution
Gen Comp Endocrinol. 2024 Mar 1;348:114449. doi: 10.1016/j.ygcen.2024.114449. Epub 2024 Jan 10.ABSTRACTWhether there is a relationship between bats' dietary patterns and evolutionary endocrine pancreas adaptation is not clearly understood. Aiming to contribute to this topic, we evaluated some metabolic and structural parameters in the following adult bats: the frugivorous Artibeus lituratus, the nectarivorous Anoura caudifer, the hematophagous Desmodus rotundus, and the insectivorous Molossus molossus. A. lituratus and A. caudifer diets consist of high amounts of simple carbohydrates, while D. rotundus and M. molossus diet...
Source: General and Comparative Endocrinology - January 12, 2024 Category: Endocrinology Authors: M Contini G D Cruz S F Althoff M B Freitas S R Taboga A Rafacho Source Type: research

Effects of different hormonal treatments on spermatogenesis advancement in hatchery-produced greater amberjack Seriola dumerili (Risso 1810)
Gen Comp Endocrinol. 2024 Mar 1;348:114447. doi: 10.1016/j.ygcen.2024.114447. Epub 2024 Jan 11.ABSTRACTIn earlier studies, wild-caught greater amberjack Seriola dumerili (Risso, 1810) males reared in sea cages showed gametogenesis impairment and low sperm production and quality. Here, we (a) examined if F1 hatchery-produced males reared in sea cages also exhibit reproductive dysfunctions and (b) evaluated the effects of gonadotropin releasing hormone agonist (GnRHa) administration through injections (GnRHainj) or sustained-release implants (GnRHaimpl), and human chorionic gonadotropin (hGC) injections on spermatogenesis/sp...
Source: General and Comparative Endocrinology - January 12, 2024 Category: Endocrinology Authors: G Ventriglia I Fakriadis M Papadaki R Zupa C Pousis M Mandalakis A Corriero C C Mylonas Source Type: research

Testosterone regulates thymic remodeling by altering metabolic reprogramming in male rats
In this study, we demonstrated that testosterone ablation (implemented by immunocastration and surgical castration) induced global metabolic changes in the thymus. Kyoto Encyclopedia of Genes and Genomes pathway enrichment for differential metabolites and metabolite set enrichment analysis for total metabolites revealed that testosterone ablation affected thymic glycolysis, glutamate metabolism, and fatty acid β-oxidation. Testosterone ablation-induced thymic regeneration was accompanied by attenuated glycolysis and glutamate metabolism and changed fatty acid composition and content. Testosterone supplementation in immuno...
Source: General and Comparative Endocrinology - January 8, 2024 Category: Endocrinology Authors: Dong Li Huan Yao Yonghao Ren Jiameng Shang Xinfa Han Xiaohan Cao Tianzeng Song Xianyin Zeng Source Type: research

Defining components of early thyroid hormone signalling through temperature-mediated activation of molecular memory in cultured Rana [lithobates] catesbeiana tadpole back skin
Gen Comp Endocrinol. 2023 Dec 29;347:114440. doi: 10.1016/j.ygcen.2023.114440. Online ahead of print.ABSTRACTThyroid hormones (THs) are essential signalling molecules for the postembryonic development of all vertebrates. THs are necessary for the metamorphosis from tadpole to froglet and exogenous TH administration precociously induces metamorphosis. In American bullfrog (Rana [Lithobates] catesbeiana) tadpoles, the TH-induced metamorphosis observed at a warm temperature (24 °C) is arrested at a cold temperature (4 °C) even in the presence of exogenous THs. However, when TH-exposed tadpoles are shifted from cold to warm ...
Source: General and Comparative Endocrinology - December 30, 2023 Category: Endocrinology Authors: E P Evans C C Helbing Source Type: research