The effect of gonadal hormones on the gene expression of brain-pituitary in protandrous black porgy, Acanthopagrus schlegelii
In this study, we conducted short-term sex steroid treatment and surgery of gonadectomy to evaluate the feedback regulation between the gonads and the brain. The qPCR results show that male phase had the highest gths transcripts; treatment with estradiol-17β (E2) or 17α-methyltestosterone (MT) resulted in the increased pituitary lhb transcripts. After surgery, apart from gnrh1, there is no difference in brain signaling genes between gonadectomy and sham fish. In the diencephalon/mesencephalon transcriptome, de novo assembly generated 283,528 unigenes; however, only 443 (0.16%) genes showed differentially expressed betwee...
Source: General and Comparative Endocrinology - March 3, 2024 Category: Endocrinology Authors: Peng-Wei Tseng Chien-Ju Lin Yuan-Han Tsao Wei-Lun Kuo Hsin-Chih Chen Sylvie Dufour Guan-Chung Wu Ching-Fong Chang Source Type: research

The effect of gonadal hormones on the gene expression of brain-pituitary in protandrous black porgy, Acanthopagrus schlegelii
In this study, we conducted short-term sex steroid treatment and surgery of gonadectomy to evaluate the feedback regulation between the gonads and the brain. The qPCR results show that male phase had the highest gths transcripts; treatment with estradiol-17β (E2) or 17α-methyltestosterone (MT) resulted in the increased pituitary lhb transcripts. After surgery, apart from gnrh1, there is no difference in brain signaling genes between gonadectomy and sham fish. In the diencephalon/mesencephalon transcriptome, de novo assembly generated 283,528 unigenes; however, only 443 (0.16%) genes showed differentially expressed betwee...
Source: General and Comparative Endocrinology - March 3, 2024 Category: Endocrinology Authors: Peng-Wei Tseng Chien-Ju Lin Yuan-Han Tsao Wei-Lun Kuo Hsin-Chih Chen Sylvie Dufour Guan-Chung Wu Ching-Fong Chang Source Type: research

The effect of gonadal hormones on the gene expression of brain-pituitary in protandrous black porgy, Acanthopagrus schlegelii
In this study, we conducted short-term sex steroid treatment and surgery of gonadectomy to evaluate the feedback regulation between the gonads and the brain. The qPCR results show that male phase had the highest gths transcripts; treatment with estradiol-17β (E2) or 17α-methyltestosterone (MT) resulted in the increased pituitary lhb trnscripts. After surgery, apart from gnrh1, there is no difference in brain signaling genes between gonadectomy and sham fish. In the diencephalon/mesencephalon transcriptome, de novo assembly generated 283,528 unigenes; however, only 443 (0.16%) genes showed differentially expressed between...
Source: General and Comparative Endocrinology - March 3, 2024 Category: Endocrinology Authors: Peng-Wei Tseng Chien-Ju Lin Yuan-Han Tsao Wei-Lun Kuo Hsin-Chih Chen Sylvie Dufour Guan-Chung Wu Ching-Fong Chang Source Type: research

The effect of gonadal hormones on the gene expression of brain-pituitary in protandrous black porgy, Acanthopagrus schlegelii
In this study, we conducted short-term sex steroid treatment and surgery of gonadectomy to evaluate the feedback regulation between the gonads and the brain. The qPCR results show that male phase had the highest gths transcripts; treatment with estradiol-17β (E2) or 17α-methyltestosterone (MT) resulted in the increased pituitary lhb trnscripts. After surgery, apart from gnrh1, there is no difference in brain signaling genes between gonadectomy and sham fish. In the diencephalon/mesencephalon transcriptome, de novo assembly generated 283,528 unigenes; however, only 443 (0.16%) genes showed differentially expressed between...
Source: General and Comparative Endocrinology - March 3, 2024 Category: Endocrinology Authors: Peng-Wei Tseng Chien-Ju Lin Yuan-Han Tsao Wei-Lun Kuo Hsin-Chih Chen Sylvie Dufour Guan-Chung Wu Ching-Fong Chang Source Type: research

The effect of gonadal hormones on the gene expression of brain-pituitary in protandrous black porgy, Acanthopagrus schlegelii
In this study, we conducted short-term sex steroid treatment and surgery of gonadectomy to evaluate the feedback regulation between the gonads and the brain. The qPCR results show that male phase had the highest gths transcripts; treatment with estradiol-17β (E2) or 17α-methyltestosterone (MT) resulted in the increased pituitary lhb trnscripts. After surgery, apart from gnrh1, there is no difference in brain signaling genes between gonadectomy and sham fish. In the diencephalon/mesencephalon transcriptome, de novo assembly generated 283,528 unigenes; however, only 443 (0.16%) genes showed differentially expressed between...
Source: General and Comparative Endocrinology - March 3, 2024 Category: Endocrinology Authors: Peng-Wei Tseng Chien-Ju Lin Yuan-Han Tsao Wei-Lun Kuo Hsin-Chih Chen Sylvie Dufour Guan-Chung Wu Ching-Fong Chang Source Type: research

The role of multiple vitellogenins in early development of fishes
Gen Comp Endocrinol. 2024 Feb 29;351:114479. doi: 10.1016/j.ygcen.2024.114479. Online ahead of print.ABSTRACTFunctions of vitellogenins have been in the limelight of fish reproductive physiology research for decades. The Vtg system of acanthomorph teleosts consists of two complete forms of Vtgs (VtgAa and VtgAb) and an incomplete form, VtgC. Insufficient uptake and processing of Vtgs and their yolk proteins lead to inadequate oocyte hydration ensuing failure in acquisition of egg buoyancy and early developmental deficiencies. This review presents a summary of our studies on utilization of multiple Vtgs in species with diff...
Source: General and Comparative Endocrinology - March 2, 2024 Category: Endocrinology Authors: Ozlem Yilmaz Craig V Sullivan Julien Bobe Birgitta Norberg Source Type: research

Loss of function in somatostatin receptor 5 has no impact on the growth of medaka fish due to compensation by the other paralogs
Gen Comp Endocrinol. 2024 Feb 25;351:114478. doi: 10.1016/j.ygcen.2024.114478. Online ahead of print.ABSTRACTSomatic growth in vertebrates is regulated endocrinologically by the somatotropic axis, headed by the growth hormone (GH) and the insulin growth factor-I (IGF-I). Somatostatin (Sst), a peptide hormone synthesized in the hypothalamus, modulates GH actions through its receptors (Sstr). Four Sstr subtypes (Sstr 1-3 and 5) have been identified in teleosts. However, little is known about whether they have a specific function or tissue expression. The aim of this study was to determine the role of sstr2 and sstr5 in the g...
Source: General and Comparative Endocrinology - February 27, 2024 Category: Endocrinology Authors: A F Boan T H Delgadin L F Canosa J I Fernandino Source Type: research

Loss of function in somatostatin receptor 5 has no impact on the growth of medaka fish due to compensation by the other paralogs
Gen Comp Endocrinol. 2024 Feb 25;351:114478. doi: 10.1016/j.ygcen.2024.114478. Online ahead of print.ABSTRACTSomatic growth in vertebrates is regulated endocrinologically by the somatotropic axis, headed by the growth hormone (GH) and the insulin growth factor-I (IGF-I). Somatostatin (Sst), a peptide hormone synthesized in the hypothalamus, modulates GH actions through its receptors (Sstr). Four Sstr subtypes (Sstr 1-3 and 5) have been identified in teleosts. However, little is known about whether they have a specific function or tissue expression. The aim of this study was to determine the role of sstr2 and sstr5 in the g...
Source: General and Comparative Endocrinology - February 27, 2024 Category: Endocrinology Authors: A F Boan T H Delgadin L F Canosa J I Fernandino Source Type: research

Loss of function in somatostatin receptor 5 has no impact on the growth of medaka fish due to compensation by the other paralogs
Gen Comp Endocrinol. 2024 Feb 25;351:114478. doi: 10.1016/j.ygcen.2024.114478. Online ahead of print.ABSTRACTSomatic growth in vertebrates is regulated endocrinologically by the somatotropic axis, headed by the growth hormone (GH) and the insulin growth factor-I (IGF-I). Somatostatin (Sst), a peptide hormone synthesized in the hypothalamus, modulates GH actions through its receptors (Sstr). Four Sstr subtypes (Sstr 1-3 and 5) have been identified in teleosts. However, little is known about whether they have a specific function or tissue expression. The aim of this study was to determine the role of sstr2 and sstr5 in the g...
Source: General and Comparative Endocrinology - February 27, 2024 Category: Endocrinology Authors: A F Boan T H Delgadin L F Canosa J I Fernandino Source Type: research

Loss of function in somatostatin receptor 5 has no impact on the growth of medaka fish due to compensation by the other paralogs
Gen Comp Endocrinol. 2024 Feb 25:114478. doi: 10.1016/j.ygcen.2024.114478. Online ahead of print.ABSTRACTSomatic growth in vertebrates is regulated endocrinologically by the somatotropic axis, headed by the growth hormone (GH) and the insulin growth factor-I (IGF-I). Somatostatin (Sst), a peptide hormone synthesized in the hypothalamus, modulates GH actions through its receptors (Sstr). Four Sstr subtypes (Sstr 1-3 and 5) have been identified in teleosts. However, little is known about whether they have a specific function or tissue expression. The aim of this study was to determine the role of sstr2 and sstr5 in the growt...
Source: General and Comparative Endocrinology - February 27, 2024 Category: Endocrinology Authors: A F Boan T H Delgadin L F Canosa J I Fernandino Source Type: research

Loss of function in somatostatin receptor 5 has no impact on the growth of medaka fish due to compensation by the other paralogs
Gen Comp Endocrinol. 2024 Feb 25:114478. doi: 10.1016/j.ygcen.2024.114478. Online ahead of print.ABSTRACTSomatic growth in vertebrates is regulated endocrinologically by the somatotropic axis, headed by the growth hormone (GH) and the insulin growth factor-I (IGF-I). Somatostatin (Sst), a peptide hormone synthesized in the hypothalamus, modulates GH actions through its receptors (Sstr). Four Sstr subtypes (Sstr 1-3 and 5) have been identified in teleosts. However, little is known about whether they have a specific function or tissue expression. The aim of this study was to determine the role of sstr2 and sstr5 in the growt...
Source: General and Comparative Endocrinology - February 27, 2024 Category: Endocrinology Authors: A F Boan T H Delgadin L F Canosa J I Fernandino Source Type: research

Evaluation of fish pituitary spheroids to study annual endocrine reproductive control
Gen Comp Endocrinol. 2024 Feb 24:114481. doi: 10.1016/j.ygcen.2024.114481. Online ahead of print.ABSTRACTThe pituitary gland is a small endocrine gland located below the hypothalamus. This gland releases several important hormones and controls the function of many other endocrine system glands to release hormones. Fish pituitary hormonal cells are controlled by neuroendocrine and sex steroid feedback. To study the complex pituitary function in vivo, we established an in vitro pituitary spheroid assay and evaluated its suitability for monitoring the annual reproductive physiological conditions in Takifugu rubripes, also kno...
Source: General and Comparative Endocrinology - February 26, 2024 Category: Endocrinology Authors: Akihiko Yamaguchi Source Type: research

SDF-1/CXCR4 signal is involved in the induction of Primordial Germ Cell migration in a model marine fish, Japanese anchovy (Engraulis japonicus)
In this study, we have focused on understanding the role of PGCs and the chemotactic SDF-1/CXCR4 signaling on gonad development of Japanese anchovy (JA, Engraulis japonicus), an upcoming marine model organism with eco-commercial values, with an aim to develop a novel, easy, and versatile gonad sterilization method. Our data showed that PGC migration related genes, i.e., sdf-1a, sdf-1b, cxcr4a, cxcr4b and vasa, are phylogenetically closer relatives of respective herring (Clupea harengus) and zebrafish (Danio rerio) homolog. Subsequently, PGC marking and live tracing experiments confirmed that PGC migration in JA initiates f...
Source: General and Comparative Endocrinology - February 26, 2024 Category: Endocrinology Authors: Issei Yahiro Oga Sato Sipra Mohapatra Koki Mukai Atsushi Toyoda Takehiko Itoh Michiya Matsuyama Tapas Chakraborty Kohei Ohta Source Type: research

Effects of neuropeptide Y on the immune-protection and intestinal tract of juvenile Micropterus salmoides
This study provides a new way to protect juvenile fish and improve its innate immunity.PMID:38401858 | DOI:10.1016/j.ygcen.2024.114480 (Source: General and Comparative Endocrinology)
Source: General and Comparative Endocrinology - February 24, 2024 Category: Endocrinology Authors: Tao Yang Kingwai Lai Yang Yu Zongzhen Liao Ran Cai Xiaozheng Yu Wensheng Li Source Type: research

Effects of neuropeptide Y on the immune-protection and intestinal tract of juvenile Micropterus salmoides
This study provides a new way to protect juvenile fish and improve its innate immunity.PMID:38401858 | DOI:10.1016/j.ygcen.2024.114480 (Source: General and Comparative Endocrinology)
Source: General and Comparative Endocrinology - February 24, 2024 Category: Endocrinology Authors: Tao Yang Kingwai Lai Yang Yu Zongzhen Liao Ran Cai Xiaozheng Yu Wensheng Li Source Type: research