Identification and functional analysis of circpdlim5a generated from pdlim5a gene splicing in the skeletal muscle of Japanese flounder (Paralichthys olivaceus)
Gen Comp Endocrinol. 2024 Mar 18;352:114500. doi: 10.1016/j.ygcen.2024.114500. Online ahead of print.ABSTRACTCircular RNAs (circRNAs) are non-coding RNAs with endogenous regulatory functions, including regulating skeletal muscle development. However, its role in the development of skeletal muscle in Japanese flounder (Paralichthys olivaceus) is not clear. Therefore we screened a candidate circpdlim5a, which is derived from the gene pdlim5a, from the skeletal muscle transcriptome of Japanese flounder. We characterized circpdlim5a, which was more stable compared to the linear RNA pdlim5a. Distributional characterization of c...
Source: General and Comparative Endocrinology - March 20, 2024 Category: Endocrinology Authors: Hao Wang Min Liu Hengtai Tang Zhirui Zhang Haishen Wen Feng He Source Type: research

Identification and functional analysis of circpdlim5a generated from pdlim5a gene splicing in the skeletal muscle of Japanese flounder (Paralichthys olivaceus)
Gen Comp Endocrinol. 2024 Mar 18;352:114500. doi: 10.1016/j.ygcen.2024.114500. Online ahead of print.ABSTRACTCircular RNAs (circRNAs) are non-coding RNAs with endogenous regulatory functions, including regulating skeletal muscle development. However, its role in the development of skeletal muscle in Japanese flounder (Paralichthys olivaceus) is not clear. Therefore we screened a candidate circpdlim5a, which is derived from the gene pdlim5a, from the skeletal muscle transcriptome of Japanese flounder. We characterized circpdlim5a, which was more stable compared to the linear RNA pdlim5a. Distributional characterization of c...
Source: General and Comparative Endocrinology - March 20, 2024 Category: Endocrinology Authors: Hao Wang Min Liu Hengtai Tang Zhirui Zhang Haishen Wen Feng He Source Type: research

Identification and functional analysis of circpdlim5a generated from pdlim5a gene splicing in the skeletal muscle of Japanese flounder (Paralichthys olivaceus)
Gen Comp Endocrinol. 2024 Mar 18;352:114500. doi: 10.1016/j.ygcen.2024.114500. Online ahead of print.ABSTRACTCircular RNAs (circRNAs) are non-coding RNAs with endogenous regulatory functions, including regulating skeletal muscle development. However, its role in the development of skeletal muscle in Japanese flounder (Paralichthys olivaceus) is not clear. Therefore we screened a candidate circpdlim5a, which is derived from the gene pdlim5a, from the skeletal muscle transcriptome of Japanese flounder. We characterized circpdlim5a, which was more stable compared to the linear RNA pdlim5a. Distributional characterization of c...
Source: General and Comparative Endocrinology - March 20, 2024 Category: Endocrinology Authors: Hao Wang Min Liu Hengtai Tang Zhirui Zhang Haishen Wen Feng He Source Type: research

Identification and functional analysis of circpdlim5a generated from pdlim5a gene splicing in the skeletal muscle of Japanese flounder (Paralichthys olivaceus)
Gen Comp Endocrinol. 2024 Mar 18:114500. doi: 10.1016/j.ygcen.2024.114500. Online ahead of print.ABSTRACTCircular RNAs (circRNAs) are non-coding RNAs with endogenous regulatory functions, including regulating skeletal muscle development. However, its role in the development of skeletal muscle in Japanese flounder (Paralichthys olivaceus) is not clear. Therefore we screened a candidate circpdlim5a, which is derived from the gene pdlim5a, from the skeletal muscle transcriptome of Japanese flounder. We characterized circpdlim5a, which was more stable compared to the linear RNA pdlim5a. Distributional characterization of circp...
Source: General and Comparative Endocrinology - March 20, 2024 Category: Endocrinology Authors: Hao Wang Min Liu Hengtai Tang Zhirui Zhang Haishen Wen Feng He Source Type: research

Structural modeling and gene expression analysis of phosvitinless vitellogenin (vgc) in the Indian freshwater murrel, Channa punctatus (Bloch, 1793)
Gen Comp Endocrinol. 2024 Mar 15:114491. doi: 10.1016/j.ygcen.2024.114491. Online ahead of print.ABSTRACTVitellogenin (Vg) is a female-specific egg-yolk precursor protein, synthesized in the liver of fish in response to estrogens. In the present study, complete gene of phosvitinless vitellogenin (vgc) was sequenced, its 3D structure was predicted and validated by web-based softwares. The complete nucleotide sequence of vgc was 4126 bp which encodes for 1272 amino acids and showed the presence of three conserved domains viz. LPD_N, DUF1943 and DUF1944. The retrieved amino acid sequence of VgC protein was subjected to in sil...
Source: General and Comparative Endocrinology - March 17, 2024 Category: Endocrinology Authors: Pooja Vijay Deepak Panwar Ritu Narwal Neeta Sehgal Source Type: research

Structural modeling and gene expression analysis of phosvitinless vitellogenin (vgc) in the Indian freshwater murrel, Channa punctatus (Bloch, 1793)
Gen Comp Endocrinol. 2024 Mar 15:114491. doi: 10.1016/j.ygcen.2024.114491. Online ahead of print.ABSTRACTVitellogenin (Vg) is a female-specific egg-yolk precursor protein, synthesized in the liver of fish in response to estrogens. In the present study, complete gene of phosvitinless vitellogenin (vgc) was sequenced, its 3D structure was predicted and validated by web-based softwares. The complete nucleotide sequence of vgc was 4126 bp which encodes for 1272 amino acids and showed the presence of three conserved domains viz. LPD_N, DUF1943 and DUF1944. The retrieved amino acid sequence of VgC protein was subjected to in sil...
Source: General and Comparative Endocrinology - March 17, 2024 Category: Endocrinology Authors: Pooja Vijay Deepak Panwar Ritu Narwal Neeta Sehgal Source Type: research

Structural modeling and gene expression analysis of phosvitinless vitellogenin (vgc) in the Indian freshwater murrel, Channa punctatus (Bloch, 1793)
Gen Comp Endocrinol. 2024 Mar 15:114491. doi: 10.1016/j.ygcen.2024.114491. Online ahead of print.ABSTRACTVitellogenin (Vg) is a female-specific egg-yolk precursor protein, synthesized in the liver of fish in response to estrogens. In the present study, complete gene of phosvitinless vitellogenin (vgc) was sequenced, its 3D structure was predicted and validated by web-based softwares. The complete nucleotide sequence of vgc was 4126 bp which encodes for 1272 amino acids and showed the presence of three conserved domains viz. LPD_N, DUF1943 and DUF1944. The retrieved amino acid sequence of VgC protein was subjected to in sil...
Source: General and Comparative Endocrinology - March 17, 2024 Category: Endocrinology Authors: Pooja Vijay Deepak Panwar Ritu Narwal Neeta Sehgal Source Type: research

A longitudinal study of endocrinology and foraging ecology of subadult gray whales prior to death based on baleen analysis
This study highlights the potential of baleen analysis to retrospectively assess gray whales' physiological status, exposure to stressors, reproductive status, and foraging ecology in the months or years leading up to their death, which can be a useful tool for conservation diagnostics to mitigate unusual mortality events.PMID:38479678 | DOI:10.1016/j.ygcen.2024.114492 (Source: General and Comparative Endocrinology)
Source: General and Comparative Endocrinology - March 13, 2024 Category: Endocrinology Authors: Alejandro Fern ández Ajó Clarissa Teixeira Daniela M D de Mello Danielle Dillon James M Rice C Loren Buck Kathleen E Hunt Matthew C Rogers Leigh G Torres Source Type: research

A longitudinal study of endocrinology and foraging ecology of subadult gray whales prior to death based on baleen analysis
This study highlights the potential of baleen analysis to retrospectively assess gray whales' physiological status, exposure to stressors, reproductive status, and foraging ecology in the months or years leading up to their death, which can be a useful tool for conservation diagnostics to mitigate unusual mortality events.PMID:38479678 | DOI:10.1016/j.ygcen.2024.114492 (Source: General and Comparative Endocrinology)
Source: General and Comparative Endocrinology - March 13, 2024 Category: Endocrinology Authors: Alejandro Fern ández Ajó Clarissa Teixeira Daniela M D de Mello Danielle Dillon James M Rice C Loren Buck Kathleen E Hunt Matthew C Rogers Leigh G Torres Source Type: research

A longitudinal study of endocrinology and foraging ecology of subadult gray whales prior to death based on baleen analysis
This study highlights the potential of baleen analysis to retrospectively assess gray whales' physiological status, exposure to stressors, reproductive status, and foraging ecology in the months or years leading up to their death, which can be a useful tool for conservation diagnostics to mitigate unusual mortality events.PMID:38479678 | DOI:10.1016/j.ygcen.2024.114492 (Source: General and Comparative Endocrinology)
Source: General and Comparative Endocrinology - March 13, 2024 Category: Endocrinology Authors: Alejandro Fern ández Ajó Clarissa Teixeira Daniela M D de Mello Danielle Dillon James M Rice C Loren Buck Kathleen E Hunt Matthew C Rogers Leigh G Torres Source Type: research

A longitudinal study of endocrinology and foraging ecology of subadult gray whales prior to death based on baleen analysis
This study highlights the potential of baleen analysis to retrospectively assess gray whales' physiological status, exposure to stressors, reproductive status, and foraging ecology in the months or years leading up to their death, which can be a useful tool for conservation diagnostics to mitigate unusual mortality events.PMID:38479678 | DOI:10.1016/j.ygcen.2024.114492 (Source: General and Comparative Endocrinology)
Source: General and Comparative Endocrinology - March 13, 2024 Category: Endocrinology Authors: Alejandro Fern ández Ajó Clarissa Teixeira Daniela M D de Mello Danielle Dillon James M Rice C Loren Buck Kathleen E Hunt Matthew C Rogers Leigh G Torres Source Type: research

Early life nutrient restriction affects hypothalamic-pituitary-interrenal axis gene expression in a diet type-specific manner
Gen Comp Endocrinol. 2024 Mar 8;352:114490. doi: 10.1016/j.ygcen.2024.114490. Online ahead of print.ABSTRACTStressful experiences in early life can alter phenotypic expression later in life. For instance, in vertebrates, early life nutrient restriction can modify later life activity of the hypothalamic-pituitary-adrenal/interrenal axis (the HPI in amphibians), including the up- and downstream regulatory components of glucocorticoid signaling. Early life nutrient restriction can also influence later life behavior and metabolism (e.g., fat accumulation). Yet, less is known about whether nutrient stress-induced carryover effe...
Source: General and Comparative Endocrinology - March 9, 2024 Category: Endocrinology Authors: Alexander M Shephard Sarah R Lagon Cristina C Led ón-Rettig Source Type: research

Early life nutrient restriction affects hypothalamic-pituitary-interrenal axis gene expression in a diet type-specific manner
Gen Comp Endocrinol. 2024 Mar 8;352:114490. doi: 10.1016/j.ygcen.2024.114490. Online ahead of print.ABSTRACTStressful experiences in early life can alter phenotypic expression later in life. For instance, in vertebrates, early life nutrient restriction can modify later life activity of the hypothalamic-pituitary-adrenal/interrenal axis (the HPI in amphibians), including the up- and downstream regulatory components of glucocorticoid signaling. Early life nutrient restriction can also influence later life behavior and metabolism (e.g., fat accumulation). Yet, less is known about whether nutrient stress-induced carryover effe...
Source: General and Comparative Endocrinology - March 9, 2024 Category: Endocrinology Authors: Alexander M Shephard Sarah R Lagon Cristina C Led ón-Rettig Source Type: research

Early life nutrient restriction affects hypothalamic-pituitary-interrenal axis gene expression in a diet type-specific manner
Gen Comp Endocrinol. 2024 Mar 8;352:114490. doi: 10.1016/j.ygcen.2024.114490. Online ahead of print.ABSTRACTStressful experiences in early life can alter phenotypic expression later in life. For instance, in vertebrates, early life nutrient restriction can modify later life activity of the hypothalamic-pituitary-adrenal/interrenal axis (the HPI in amphibians), including the up- and downstream regulatory components of glucocorticoid signaling. Early life nutrient restriction can also influence later life behavior and metabolism (e.g., fat accumulation). Yet, less is known about whether nutrient stress-induced carryover effe...
Source: General and Comparative Endocrinology - March 9, 2024 Category: Endocrinology Authors: Alexander M Shephard Sarah R Lagon Cristina C Led ón-Rettig Source Type: research

Early life nutrient restriction affects hypothalamic-pituitary-interrenal axis gene expression in a diet type-specific manner
Gen Comp Endocrinol. 2024 Mar 7:114490. doi: 10.1016/j.ygcen.2024.114490. Online ahead of print.ABSTRACTStressful experiences in early life can alter phenotypic expression later in life. For instance, in vertebrates, early life nutrient restriction can modify later life activity of the hypothalamic-pituitary-adrenal/interrenal axis (the HPI in amphibians), including the up- and downstream regulatory components of glucocorticoid signaling. Early life nutrient restriction can also influence later life behavior and metabolism (e.g., fat accumulation). Yet, less is known about whether nutrient stress-induced carryover effects ...
Source: General and Comparative Endocrinology - March 9, 2024 Category: Endocrinology Authors: Alexander M Shephard Sarah R Lagon Cristina C Led ón-Rettig Source Type: research