Gastrointestinal Endoscopy Clinics of North America This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Cost-Effectiveness of Screening, Surveillance, and Endoscopic Eradication Therapies for Managing the Burden of Esophageal Adenocarcinoma
The authors conducted a review of the literature of cost-effectiveness analyses regarding management of Barrett ’s esophagus, including screening, surveillance, and treatment strategies. Because of the presence of multiple systematic reviews on this topic, they chose to focus on more recent economic analyses, with an emphasis on comparative modeling because these analyses have been demonstrated to achieve g reater validity and impact when there are multiple competing strategies that are clinically reasonable to pursue. The authors identified areas of consensus across studies regarding management strategies and also areas...
Source: Gastrointestinal Endoscopy Clinics of North America - October 26, 2020 Category: Gastroenterology Authors: Joel H. Rubenstein, John M. Inadomi Source Type: research

Advanced Imaging and Sampling in Barrett ’s Esophagus
Because the current Barrett ’s esophagus (BE) surveillance protocol suffers from sampling error of random biopsies and a high miss-rate of early neoplastic lesions, many new endoscopic imaging and sampling techniques have been developed. None of these techniques, however, have significantly increased the diagnostic yield of BE neoplasia. In fact, these techniques have led to an increase in the amount of visible information, yet endoscopists and pathologists inevitably suffer from variations in intra- and interobserver agreement. Artificial intelligence systems have the potential to overcome these endoscopist-dependent li...
Source: Gastrointestinal Endoscopy Clinics of North America - October 26, 2020 Category: Gastroenterology Authors: Maarten R. Struyvenberg, Albert J. de Groof, Jacques J. Bergman, Fons van der Sommen, Peter H.N. de With, Vani J.A. Konda, Wouter L. Curvers Source Type: research

Advances in Biomarkers for Risk Stratification in Barrett ’s Esophagus
This report focuses only on those biomarkers that appear most promisi ng based on the availability of multiple published studies corroborating good results, and on the commercial availability of the test. These promising biomarkers include p53 immunostaining, TissueCypher, BarreGEN, and wide-area transepithelial sampling with computer-assisted 3-dimensional analysis ( WATS3D). (Source: Gastrointestinal Endoscopy Clinics of North America)
Source: Gastrointestinal Endoscopy Clinics of North America - October 26, 2020 Category: Gastroenterology Authors: Rhonda F. Souza, Stuart Jon Spechler Source Type: research

Current Status of Chemoprevention in Barrett ’s Esophagus
Candidates for chemoprevention in Barrett ’s esophagus have long been suggested and there has been observational data to support many drugs, including statins, hormone replacement therapy, metformin, proton pump inhibitor therapy, and aspirin. Proton pump inhibitor therapy and aspirin are the most promising agents. Data suggest that aspir in and proton pump inhibitor therapy can decrease the risk of neoplastic progression in Barrett’s esophagus. Further, the combination of aspirin and proton pump inhibitor therapy decrease all-cause mortality by approximately 33%. Future guideline groups need to evaluate the evidence r...
Source: Gastrointestinal Endoscopy Clinics of North America - October 26, 2020 Category: Gastroenterology Authors: Paul Moayyedi, Hashem B. El-Serag Source Type: research

Surgical Management of Barrett ’s-Related Neoplasia
The management of Barrett ’s-related neoplasia has benefited from advances in endoscopic assessment, resection, and ablation, along with improved pathologic and radiographic staging. The development of specialized, high-volume esophageal multidisciplinary teams, with improvements in patient selection, preparation, perioper ative care, minimally invasive operative approaches, and enhanced recovery after surgery programs, has contributed to improved outcomes for patients undergoing esophagectomy for Barrett’s-related neoplasia. (Source: Gastrointestinal Endoscopy Clinics of North America)
Source: Gastrointestinal Endoscopy Clinics of North America - October 23, 2020 Category: Gastroenterology Authors: Akshay Pratap, Martin D. McCarter, Thomas J. Watson Source Type: research