Gastrointestinal Endoscopy Clinics of North America This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Improving the Early Diagnosis of Gastric Cancer
Gastric cancer (GC) remains a leading cause of cancer morbidity and mortality worldwide. Outcomes from GC remain poor, especially in Western nations where cancer diagnosis is usually at advanced stages where curative resection is not possible. By contrast, nations of East Asia have adopted methods of population-level screening with improvements in stage of diagnosis and survival. In this review, the authors discuss the epidemiology of GC in Western populations, highlight at-risk populations who may benefit from screening, overview screening modalities, and discuss promising approaches to early GC detection. (Source: Gastro...
Source: Gastrointestinal Endoscopy Clinics of North America - May 28, 2021 Category: Gastroenterology Authors: Robert J. Huang, Joo Ha Hwang Source Type: research

Chemoprevention Against Gastric Cancer
Gastric cancer is the fifth most common cause of cancer and the third leading cause of cancer-related deaths globally. The number of gastric cancer-related deaths is only projected to increase, attributable primarily to the expanding aging population. Prevention is a mainstay of gastric cancer control programs, particularly in the absence of accurate, noninvasive modalities for screening and early detection, and the absence of an infrastructure for this purpose in the majority of countries worldwide. Herein, we discuss the evidence for several chemopreventive agents, along with putative mechanisms. There remains a clear, u...
Source: Gastrointestinal Endoscopy Clinics of North America - May 28, 2021 Category: Gastroenterology Authors: Shailja C. Shah, Richard M. Peek Source Type: research

Endoscopic Advances for Gastric Neoplasia Detection
This article explores advances in endoscopic neoplasia detection with supporting clinical evidence and future aims. The ability to detect early gastric neoplastic lesions amenable to curative endoscopic submucosal dissection provides the opportunity to decrease gastric cancer mortality rates. Newer imaging techniques offer enhanced views of mucosal and microvascular structures and show promise in differentiating benign from malignant lesions and improving targeted biopsies. Conventional chromoendoscopy is well studied and validated. Narrow band imaging demonstrates superiority over magnified white light. Autofluorescence i...
Source: Gastrointestinal Endoscopy Clinics of North America - May 28, 2021 Category: Gastroenterology Authors: Andrew Canakis, Raymond Kim Source Type: research

Endoscopic Resection of Gastric Cancer
With improvements in the early detection of early gastric cancer (EGC) and advances in therapeutic techniques, endoscopic resection (ER) for EGC has become widely adopted in East Asian and Western countries. Endoscopic submucosal dissection has higher rates of en bloc, complete, and curative resections with lower rates of local recurrence than that of endoscopic mucosal resection. ER is a minimally invasive method with low morbidity that provides excellent outcomes. ER for EGC is a safe, effective method, preserving organ function and thus maintaining the patient ’s quality of life, and is recognized as the first-line tr...
Source: Gastrointestinal Endoscopy Clinics of North America - May 28, 2021 Category: Gastroenterology Authors: Ga Hee Kim, Hwoon-Yong Jung Source Type: research

Advances in Systemic Therapy for Gastric Cancer
Gastric cancer represents a major global health problem. Approximately half of patients are diagnosed with early stage disease and surgical resection is potentially curative. The addition of combination chemotherapy, with or without radiotherapy, to surgery has been shown to improve outcomes. In metastatic disease, combination chemotherapy in the form of 2- or 3-drug regimens has been used. The aim of this chapter is to summarize currently approved systemic treatment options for gastric cancer and to highlight several promising treatments currently under investigation. (Source: Gastrointestinal Endoscopy Clinics of North America)
Source: Gastrointestinal Endoscopy Clinics of North America - May 28, 2021 Category: Gastroenterology Authors: Andrew Hsu, Alexander G. Raufi Source Type: research

Inherited Predisposition to Gastric Cancer
Approximately 10% of patients with gastric cancer show familial aggregation and up to 3% are related to an inherited cancer syndrome. There are multiple germline pathogenic variants and cancer syndromes associated with an increased risk of gastric cancer. Appropriate assessment of familial and genetic risk may allow a personalized approach to gastric cancer prevention through screening and risk-reducing surgeries. The ability to better identify carriers with pathogenic genetic variants associated with gastric cancer before a diagnosis of cancer requires effective genetic risk assessment and testing, followed by optimal scr...
Source: Gastrointestinal Endoscopy Clinics of North America - May 28, 2021 Category: Gastroenterology Authors: Sheila D. Rustgi, Charlotte K. Ching, Fay Kastrinos Source Type: research

Surgical Treatment for Gastric Cancer
This article aims to provide this information while acknowledging areas of surgical management that are still controversial. (Source: Gastrointestinal Endoscopy Clinics of North America)
Source: Gastrointestinal Endoscopy Clinics of North America - May 28, 2021 Category: Gastroenterology Authors: Ian Solsky, Haejin In Source Type: research

Gastric Cancer:
Gastric cancer (GC), specifically gastric adenocarcinoma, is the fifth most common cancer and the third leading cause of cancer death globally and has been categorized as a neglected cancer by the World Health Organization.1,2 Usually diagnosed at advanced stages, GC has a 5-year survival rate of ∼30%.3 In the United States, there are stark disparities, with blacks, Hispanics, and Asians having a nearly 2-fold greater risk of developing or dying from GC compared with whites,4 reflecting differences in risk factors, such as Helicobacter pylori infection and smoking, as well as access to pri mary prevention5 and care. (Sou...
Source: Gastrointestinal Endoscopy Clinics of North America - May 28, 2021 Category: Gastroenterology Authors: Chin Hur Tags: Preface Source Type: research

Turning a Spotlight on Gastric Cancer
Gastric adenocarcinoma is a common and highly lethal cancer worldwide. The disease is of lower incidence in the United States and other western countries. The lower incidence is probably related in part to the decreasing incidence of gastric Helicobacter pylori infections in the west. A reverse effect of the decline in H pylori in the west has been the dramatic rise in Barrett ’s esophagus and esophageal adenocarcinoma primarily affecting white men. Adenocarcinoma of the stomach, on the other hand, excluding esophagogastric junction cancer, more commonly occurs in blacks, Hispanics, and Asians, creating health disparitie...
Source: Gastrointestinal Endoscopy Clinics of North America - May 28, 2021 Category: Gastroenterology Authors: Charles J. Lightdale Tags: Foreword Source Type: research

Gastric Cancer
GASTROINTESTINAL ENDOSCOPY CLINICS OF NORTH AMERICA (Source: Gastrointestinal Endoscopy Clinics of North America)
Source: Gastrointestinal Endoscopy Clinics of North America - May 28, 2021 Category: Gastroenterology Authors: CHIN HUR Source Type: research

Copyright
ELSEVIER (Source: Gastrointestinal Endoscopy Clinics of North America)
Source: Gastrointestinal Endoscopy Clinics of North America - May 28, 2021 Category: Gastroenterology Source Type: research

Contributors
CHARLES J. LIGHTDALE, MD (Source: Gastrointestinal Endoscopy Clinics of North America)
Source: Gastrointestinal Endoscopy Clinics of North America - May 28, 2021 Category: Gastroenterology Source Type: research

Contents
Charles J. Lightdale (Source: Gastrointestinal Endoscopy Clinics of North America)
Source: Gastrointestinal Endoscopy Clinics of North America - May 28, 2021 Category: Gastroenterology Source Type: research

Forthcoming Issues
Optimizing Endoscopic Operations (Source: Gastrointestinal Endoscopy Clinics of North America)
Source: Gastrointestinal Endoscopy Clinics of North America - May 28, 2021 Category: Gastroenterology Source Type: research

The Future of Endoscopic Operations after the Coronavirus Pandemic
The COVID-19 pandemic represents an unprecedented health crisis that has challenged GI practices in major ways. Rapidly implemented global shutdowns resulted in sudden delays of endoscopic procedures. As the country is moving towards a full reopening, practices are wrestling with the challenge of a complete retooling of their operations with the goal of quickly returning to providing high-quality care to large numbers of patients in a safe and effective manner. At the same time, the longer-term impact of the pandemic on future practice operations needs to be assessed: What will post-pandemic GI care look like? Will some as...
Source: Gastrointestinal Endoscopy Clinics of North America - May 25, 2021 Category: Gastroenterology Authors: Klaus Mergener Source Type: research