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Endocrine immune-related adverse effects of immune-checkpoint inhibitors
Expert Rev Endocrinol Metab. 2023 Sep 8:1-11. doi: 10.1080/17446651.2023.2256841. Online ahead of print.ABSTRACTINTRODUCTION: Immune-checkpoint inhibitor therapy modulates the response of the immune system acting against cancer. Two pathways impacted by this kind of treatment are the CTLA4 and the PD-1/PD-L1 pathways. ICI therapy can trigger autoimmune adverse effects, known as immune-related Adverse Events (irAEs).AREAS COVERED: This review focuses on irAEs which affect the endocrine system. This review elucidates the pathways used by these drugs with a focus on the hypothetical pathogenesis at their basis. In fact, the p...
Source: Expert Review of Endocrinology and Metabolism - September 8, 2023 Category: Endocrinology Authors: Viola Trevisani Lorenzo Iughetti Laura Lucaccioni Barbara Predieri Source Type: research

Identification of individuals at risk of hepatocellular carcinoma: screening for clinically significant liver fibrosis in patients with T2DM
Expert Rev Endocrinol Metab. 2023 Aug 17:1-5. doi: 10.1080/17446651.2023.2248242. Online ahead of print.NO ABSTRACTPMID:37587863 | DOI:10.1080/17446651.2023.2248242 (Source: Expert Review of Endocrinology and Metabolism)
Source: Expert Review of Endocrinology and Metabolism - August 17, 2023 Category: Endocrinology Authors: Tina Reinson Ryan M Buchanan Christopher D Byrne Source Type: research