Is euthyroidism within reach for all?
Expert Rev Endocrinol Metab. 2023 Oct 3:1-4. doi: 10.1080/17446651.2023.2267120. Online ahead of print.NO ABSTRACTPMID:37811647 | DOI:10.1080/17446651.2023.2267120 (Source: Expert Review of Endocrinology and Metabolism)
Source: Expert Review of Endocrinology and Metabolism - October 9, 2023 Category: Endocrinology Authors: Jacqueline Jonklaas Source Type: research

Promising targetable biomarkers in pancreatic neuroendocrine tumours
Expert Rev Endocrinol Metab. 2023 Sep-Nov;18(5):387-398. doi: 10.1080/17446651.2023.2248239. Epub 2023 Sep 27.ABSTRACTINTRODUCTION: In the treatment scenario of PanNETs-targeted therapies are desired but limited, as rarity and heterogeneity on PanNETs pose limitations to their development.AREAS COVERED: We performed a literature review searching for promising druggable biomarkers and potential treatments to be implemented in the next future. We focused on treatments which have already reached clinical experimentation, although in early phases. Six targets were identified, namely Hsp90, HIFa, HDACs, CDKs, uPAR, and DDR. Eve...
Source: Expert Review of Endocrinology and Metabolism - September 25, 2023 Category: Endocrinology Authors: M Borghesani L Gervaso C A Cella L Benini D Ciardiello L Algeri A Ferrero C Valenza L Guidi M G Zampino F Spada N Fazio Source Type: research

Promising targetable biomarkers in pancreatic neuroendocrine tumours
Expert Rev Endocrinol Metab. 2023 Sep 24:1-12. doi: 10.1080/17446651.2023.2248239. Online ahead of print.ABSTRACTINTRODUCTION: In the treatment scenario of PanNETs-targeted therapies are desired but limited, as rarity and heterogeneity on PanNETs pose limitations to their development.AREAS COVERED: We performed a literature review searching for promising druggable biomarkers and potential treatments to be implemented in the next future. We focused on treatments which have already reached clinical experimentation, although in early phases. Six targets were identified, namely Hsp90, HIFa, HDACs, CDKs, uPAR, and DDR. Even tho...
Source: Expert Review of Endocrinology and Metabolism - September 25, 2023 Category: Endocrinology Authors: M Borghesani L Gervaso C A Cella L Benini D Ciardiello L Algeri A Ferrero C Valenza L Guidi M G Zampino F Spada N Fazio Source Type: research

Endocrine factors associated with infertility in women: an updated review
Expert Rev Endocrinol Metab. 2023 Sep 13:1-19. doi: 10.1080/17446651.2023.2256405. Online ahead of print.ABSTRACTINTRODUCTION: Infertility is defined as the inability to conceive after unprotected sexual intercourse for at least 12 consecutive months. Our objective is to present an updated narrative review on the endocrine causes of infertility in women.AREAS COVERED: A comprehensive review was conducted using Scielo, Scopus, and EMBASE databases, comprising 245 articles. The pathophysiology of infertility in women was described, including endocrinopathies such as hypothalamic amenorrhea, hyperprolactinemia, polycystic ova...
Source: Expert Review of Endocrinology and Metabolism - September 13, 2023 Category: Endocrinology Authors: Marcio Jos é Concepción-Zavaleta Julia Cristina Coronado-Arroyo Juan Eduardo Quiroz-Aldave Mar ía Del Carmen Durand-Vásquez Sof ía Pilar Ildefonso-Najarro Luciana Del Pilar Rafael-Robles Luis Alberto Concepci ón-Urteaga Elman Rolando Gamarra-Osorio Source Type: research