Does Functional Outcome Improve with Time Postsurgery for Hirschsprung Disease?
Eur J Pediatr SurgDOI: 10.1055/s-0034-1544053 Purpose Constipation and incontinence are significant problems following pull-through surgery for Hirschsprung disease (HD). There is evidence that these problems improve with time. However, there is also evidence showing no improvements and furthermore, significant long-term data are lacking for the newer endorectal pull-through. We aim to determine if there is clinical evidence that show improvements in functional outcomes with time after an endorectal pull-through surgery for HD. Methods We utilized the validated pediatric incontinence and constipation ...
Source: European Journal of Pediatric Surgery - February 2, 2015 Category: Surgery Authors: Aworanti, Olugbenga MichaelMcDowell, Dermot ThomasMartin, Ian MichaelQuinn, Feargal Tags: Original Article Source Type: research

European Pediatric Surgeons' Association (EUPSA)
Eur J Pediatr Surg 2015; 25: 01-02DOI: 10.1055/s-0035-1544214Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - January 22, 2015 Category: Surgery Authors: Wester, Tomas Tags: Editorial Source Type: research

Best Oxygenation Index on Day 1: A Reliable Marker for Outcome and Survival in Infants with Congenital Diaphragmatic Hernia
Eur J Pediatr SurgDOI: 10.1055/s-0034-1393960 Aim of the Study Severe lung hypoplasia and persistent pulmonary hypertension are the main determining factors of survival in infants with congenital diaphragmatic hernia (CDH). The oxygenation index (ratio of delivered oxygen and its arterial level) closely reflects lung function. Single-institution studies have reported that best oxygenation index on day 1 of life (BOI-d1) is the most reliable postnatal predictor of survival in CDH. The aim of this study was to evaluate the predictive value of BOI-d1 in four disparate high volume centers in Europe. Methods&em...
Source: European Journal of Pediatric Surgery - January 5, 2015 Category: Surgery Authors: Ruttenstock, ElkeWright, NaomiBarrena, S.Krickhahn, AnnikaCastellani, ChristophDesai, Ashish P.Rintala, RistoTovar, JuanTill, HolgerZani, AugustoSaxena, AmulyaDavenport, Mark Tags: Original Article Source Type: research

Serum and Urinary Values of CA 19-9 and TGFß1 in a Rat Model of Partial or Complete Ureteral Obstruction
Conclusion Urinary CA 19-9 correlated negatively with ureteral obstruction grade. Immunohistochemistry depicted CA 19-9 expression on epithelial tubular cells cytoplasm, suggesting renal origin. Serum and urinary TGFß1 did not show alterations in response to severity and length of urinary obstruction, which might be associated with less intense renal remodeling.[...]Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents  |  Abstract  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - January 5, 2015 Category: Surgery Authors: Lopes, Roberto IglesiasDénes, Francisco TiborBartolamei, Matheus GesualdoReis, SabrinaSanches, Talita RojasLeite, Kátia RamosSrougi, MiguelSeguro, Antônio Carlos Tags: Original Article Source Type: research

Treatment and Follow-Up of Patients with Long-Gap Esophageal Atresia: 15 Years' of Experience from the Western Region of Sweden
Conclusion LGEA is a severe congenital malformation, with severe morbidity. No mortality was seen. MBW could be a useful tool for the early detection of progressive pulmonary damage.[...]Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents  |  Abstract  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - January 5, 2015 Category: Surgery Authors: Jönsson, LinusFriberg, Lars GöranGatzinsky, VladimirKötz, KarstenSillén, UllaAbrahamsson, Kate Tags: Original Article Source Type: research

First Case Studies of Successful ABO-Incompatible Living-Related Liver Transplantation in Infants in Germany
Conclusion ABOi LRLT seems to be safe without an escalation of immunosuppression and should be considered as an additional option to timely facilitate the transplantation.[...]Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents  |  Abstract  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - January 2, 2015 Category: Surgery Authors: Schukfeh, NagoudLenz, VeronikaMetzelder, Martin L.Paul, AndreasMathe, ZoltanKathemann, SimoneHoyer, Peter F.Dohna-Schwake, ChristianGerner, Patrick Tags: Original Article Source Type: research

Introduction to the Review Papers Series on Novelties and State of the Art in Pediatric Surgical Oncology
Eur J Pediatr Surg 2014; 24: 441-442DOI: 10.1055/s-0034-1396902Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - December 24, 2014 Category: Surgery Authors: Czauderna, Piotr Tags: Editorial Source Type: research

Clinical Negligence Claims in Pediatric Surgery in England: Pattern and Trends
Conclusion Two-thirds of all claims in pediatric surgery resulted in payment to claimant, and the commonest reasons for claims were postoperative complications, delayed treatment, and/or diagnosis. Nearly a quarter of successful claims were in cases where negligence resulted in case fatality. Pediatric surgeons should be aware of common diagnostic and treatment shortfalls as high-risk areas of increased susceptibility to clinical negligence claims.[...]Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents  |  Abstract  |  Full text (Sour...
Source: European Journal of Pediatric Surgery - December 19, 2014 Category: Surgery Authors: Thyoka, Mandela Tags: Original Article Source Type: research

Risk Factors for the Recurrence of the Congenital Diaphragmatic Hernia—Report from the Long-Term Follow-Up Study of Japanese CDH Study Group
Eur J Pediatr SurgDOI: 10.1055/s-0034-1395486 Aim of the Study Few follow-up studies focused on the recurrence regarding the postoperative course of congenital diaphragmatic hernia (CDH) survivors. The aim of this study was to report on risk factor for CDH patients who had the recurrence during the follow-up. Materials and Methods A multicenter retrospective survey was conducted on neonates diagnosed to have CDH between January 2006 and December 2010. Follow-up survey was conducted between September 2013 and October 2013 (ethical approval: No. 25–222). Nine institutions agreed to participate in ...
Source: European Journal of Pediatric Surgery - December 19, 2014 Category: Surgery Authors: Nagata, KoujiUsui, NoriakiTerui, KeitaTakayasu, HajimeGoishi, KeijiHayakawa, MasahiroTazuke, YukoYokoi, AkikoOkuyama, HiroomiTaguchi, Tomoaki Tags: Original Article Source Type: research

Secondary Plastic Closure of Gastroschisis Is Associated with a Lower Incidence of Mechanical Ventilation
This study compared requirements for mechanical ventilation and general anesthesia, nutritional care, and outcomes between SPC and SSC. Patients and Methods We included patients with primary staged-silo reduction with a 1-year minimum follow-up. SPC was performed at bedside with sedation using a nonadherent dressing. SSC was performed in operating room under general anesthesia using standard surgical techniques. Results This retrospective study included 64 patients, 23 SPC and 41 SSC. The characteristics of the two groups were comparable. Mechanical ventilation was used for 15 SPC and 41 SSC (p&thinsp...
Source: European Journal of Pediatric Surgery - December 19, 2014 Category: Surgery Authors: Dariel, AnnePoocharoen, Wannisade Silva, NicolePleasants, HazelGerstle, Justin Ted Tags: Original Article Source Type: research

Advances in the Surgical Treatment of Neuroblastoma: A Review
This article also reviews the surgical approaches to difficult thoracic and abdominal tumors, as well as the role for minimally invasive surgery in the management of localized neuroblastoma.[...]Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents  |  Abstract  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - December 8, 2014 Category: Surgery Authors: Murphy, Jennifer M.La Quaglia, Michael P. Tags: Review Article Source Type: research

Advances in Fibrolamellar Hepatocellular Carcinoma: A Review
Eur J Pediatr SurgDOI: 10.1055/s-0034-1396420Fibrolamellar hepatocellular carcinoma is a rare primary liver tumor that often arises in the absence of cirrhosis or viral hepatitis. Compared with hepatocellular carcinoma, patients are typically younger with less comorbidities. Diagnosis is often multimodal and requires a high level of suspicion, as traditional liver pathology markers, such as serum α fetoprotein and transaminases, are often normal. Overall, patients respond well to surgical resection but recurrences are frequent, and alternative therapies, such as chemotherapy and radiation, are not well studied. Curre...
Source: European Journal of Pediatric Surgery - December 8, 2014 Category: Surgery Authors: Lim, Irene Isabel P.Farber, Benjamin A.LaQuaglia, Michael P. Tags: Review Article Source Type: research

A Review on Surgical Techniques and Organ Sparing Procedures in Bladder/Prostate Rhabdomyosarcoma
Eur J Pediatr SurgDOI: 10.1055/s-0034-1396424The treatment outcomes in children with bladder/prostate rhabdomyosarcoma (B/P RMS) have considerably improved in the past few decades. Current protocols incorporate chemotherapy, radiotherapy, and surgery (radical or organ sparing). Using this multimodal and multidisciplinary approach, the cure rates for nonmetastatic RMS have gradually increased from 25% in the 1970s, and 70% in the 1990s, to over 80% in the 2000s. Surgery plays a role not only in the diagnosis and management of all stages of B/P RMS, but also in the urinary reconstruction and long-term follow-up. Furthermore,...
Source: European Journal of Pediatric Surgery - December 8, 2014 Category: Surgery Authors: Komasara, LeszekGołębiewski, AndrzejAnzelewicz, StefanCzauderna, Piotr Tags: Review Article Source Type: research

Advances in Oncologic Imaging
Eur J Pediatr SurgDOI: 10.1055/s-0034-1396423Over the past two decades, there has been an increased reliance on radiologic imaging to diagnose and stage malignancies. This increased reliance on imaging has occurred because the quality of imaging has improved markedly. Currently, modalities such as MRI and CT allow the radiologist to obtain highly detailed images of the human body with a resolution of less than 1mm. More recently, researchers have shifted their focus from anatomic imaging to functional imaging. This burgeoning field of radiology strives to provide quantitative information regarding the behavior of tumors (o...
Source: European Journal of Pediatric Surgery - December 5, 2014 Category: Surgery Authors: Towbin, Alexander J.Trout, Andrew T.Roebuck, Derek J. Tags: Review Article Source Type: research

Minimally Invasive Surgery in Childhood Cancer: A Challenging Future
Conclusion MIS is a promising method for removal of thoracic and abdominal malignancies as long as oncological principles are strictly followed. Long-term follow-up is mandatory to further delineate objective indications.[...]Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents  |  Abstract  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - December 5, 2014 Category: Surgery Authors: Peycelon, MatthieuAudry, GeorgesIrtan, Sabine Tags: Review Article Source Type: research

Current Concepts in Surgery for Wilms Tumor—The Risk and Function-Adapted Strategy
This article describes the current status of surgical approach to Wilms tumor. Combined multimodal treatment including classical open nephrectomy is still the most recommended and offers excellent survivals. Patients suffering from Wilms tumor as potentially very long-term survivors also need great care of quality of their further life. Nephron-sparing surgery seems an important step in this regard; however, selection of patients is necessary to avoid failures and decreasing survival rate. A new method of describing this kind of procedure developed within the SIOP Renal Tumours Study Group (RTSG) offers an opportunity for ...
Source: European Journal of Pediatric Surgery - December 5, 2014 Category: Surgery Authors: Godzinski, JanGraf, NorbertAudry, Georges Tags: Review Article Source Type: research

Sentinel Node Biopsy in Pediatric Patients: The Experience in a Single Institution
We report our experience with 29 patients who were evaluated with SLNB during the past 12 years: 9 alveolar rhabdomyosarcoma, 1 embryonal rhabdomyosarcoma, 7 Ewing Sarcoma/pPNET, 1 clear cells sarcoma, 2 epithelioid sarcoma, 1 epithelioid sclerosing fibrosarcoma, 3 myxoid liposarcoma, 1 adult fibrosarcoma, 1 malignant peripheral nerve sheath tumor, 1 undifferentiated sarcoma, 1 sarcoma not otherwise specified, and 1 melanoma. All, but one, patients underwent a lymphoscintigraphy, and in more than half of the patients, an intraoperative lymphatic mapping with a blue dye injection was performed. In our experience, SLNB was a...
Source: European Journal of Pediatric Surgery - December 5, 2014 Category: Surgery Authors: Dall'Igna, PatriziaDe Corti, FedericaAlaggio, RitaCecchetto, Giovanni Tags: Original Article Source Type: research

Increased Inflammatory Reaction to Intestinal Ischemia-Reperfusion in Neonatal versus Adult Mice
This study tests the hypothesis that the neonatal gut is prone to inflammation, by comparing the inflammatory reaction of neonatal and adult murine intestine to ischemia and reperfusion. Methods Neonatal (4 days, n = 36) and adult (4 weeks, n = 12) C57BL/6J mice were randomly divided between ischemia-reperfusion (IR) and untreated controls (Con). In IR animal's intestinal ischemia was induced by clamping the superior mesenteric artery (30 minutes) followed by reperfusion (4 hours). After the experiment, RNA was extracted from the small intestines and the expression of the chemokines C...
Source: European Journal of Pediatric Surgery - November 25, 2014 Category: Surgery Authors: Yu, YiKlemann, ChristianFeng, XiaoyanGinzel, MarcoVieten, GertrudLacher, MartinUre, BennoKuebler, Joachim F. Tags: Original Article Source Type: research

Clinical Outcome of Cloacal Exstrophy, Current Status, and a Change in Surgical Management
Discussion Despite medical efforts and development in treatment and support, satisfaction in outcome of cloacal exstrophy remains a challenge. Although reconstruction may be very difficult, male genital reconstruction in 46 XY patients has been given preference for more than a decade. A specialized multidisciplinary team should provide lifelong colorectal, urological, sexual, and psychosocial support to these patients, taking into account their age and phase of life.[...]Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents  |  Abstract  | &n...
Source: European Journal of Pediatric Surgery - November 25, 2014 Category: Surgery Authors: Vliet, Rob vanRoelofs, Luc A. J.Rassouli-Kirchmeier, Roxanade Gier, Robert P. E.Claahsen-van der Grinten, Hedi L.Verhaak, ChrisHosman, Allard J.Beerendonk, Catharina C. M.van Lindert, Erik J.Willemsen, Michel A. A. P.Wijnen, Marc H. W. A.Feitz, Wout F. J. Tags: Original Article Source Type: research

Diagnostic Accuracy of Meckel Scan with Initial Hemoglobin Level to Detect Symptomatic Meckel Diverticulum
Eur J Pediatr SurgDOI: 10.1055/s-0034-1387949 Introduction Meckel scan is an effective tool for diagnosing symptomatic Meckel diverticulum (MD). However, the clinical relevance of Meckel scan remains controversial because of its rare use. To evaluate the clinical relevance of Meckel scan with initial hemoglobin (Hb) level, we investigated its diagnostic accuracy in our patient population over a 10-year period, and we propose clinical considerations for Meckel scan with initial Hb levels. Patients and Methods A total of 70 patients (41 males and 29 females; median age, 3 years; range, 3 months to 49 ye...
Source: European Journal of Pediatric Surgery - November 25, 2014 Category: Surgery Authors: Suh, MinseokLee, Ho-YoungJung, KyuwhanKim, Sang Eun Tags: Original Article Source Type: research

Preliminary Analysis of the Surgical Treatment of Anorectal Malformations in Russia
This study is a collaborative effort to provide Russian Consensus on treatment of ARM.[...]Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents  |  Abstract  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - November 2, 2014 Category: Surgery Authors: Morozov, DmitryPimenova, EvgeniyaOculov, EvgeniyGusev, AlexeyUtkina, Kseniya Tags: Special Report Source Type: research

Health Status and Quality of Life in Adult Biliary Atresia Patients Surviving with Their Native Livers
Eur J Pediatr SurgDOI: 10.1055/s-0034-1394278Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - October 27, 2014 Category: Surgery Authors: Lind, Robert C.de Vries, WillemienKeyzer-Dekker, Claudia M. G.Peeters, Paul M. J. G.Verkade, Henkjan J.Hoekstra-Weebers, Josette E. H. M.van der Steeg, Alida F. W.Hulscher, Jan B. F. Tags: Erratum Source Type: research

International Survey on the Management of Necrotizing Enterocolitis
Eur J Pediatr SurgDOI: 10.1055/s-0034-1387942 Aim The aim of this study is to define patterns in the management of necrotizing enterocolitis (NEC). Methods A total of 80 delegates (81% senior surgeons) from 29 (20 European) countries completed a survey at the European Pediatric Surgeons' Association 2013 annual meeting. Results Overall, 59% surgeons work in centers where > 10 cases of NEC are treated per year. Diagnosis: 76% surgeons request both anteroposterior and lateral abdominal X-rays, which are performed at regular intervals by 66%; 50% surgeons also request Doppler ...
Source: European Journal of Pediatric Surgery - October 26, 2014 Category: Surgery Authors: Zani, AugustoEaton, SimonPuri, PremRintala, RistoLukac, MarijaBagolan, PietroKuebler, Joachim F.Hoellwarth, Michael E.Wijnen, ReneTovar, JuanPierro, Agostino Tags: Original Article Source Type: research

Controversies in Choledochal Malformations: A Survey among Dutch Pediatric Surgeons
Conclusion Dutch pediatric surgeons demonstrate a wide variety of opinions regarding diagnostic workup, treatment, and follow-up of CM. While most surgeons encounter CM up to 2 times/y, there is an association between exposure and several of the outcome parameters. Some of the answers are not in line with the expert opinion. This demonstrates that there is a need for evidence-based (inter)national guidelines regarding the diagnostic approach, management, and follow-up.[...]Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents  |  Abstract  | ...
Source: European Journal of Pediatric Surgery - October 26, 2014 Category: Surgery Authors: van den Eijnden, Maria Hendrina Antoinettede Kleine, Ruben H.Verkade, Henkjan J.Wilde, Jim C. H.Peeters, Paul M. J. G.Hulscher, Jan B. F. Tags: Original Article Source Type: research

Glypican 3 Expression in Pediatric Malignant Solid Tumors
Conclusion Most cases of hepatoblastoma and yolk sac tumor, and some cases of other tumors were found to express GPC3 either histologically or serologically. On the other hand, GPC3 was physiologically expressed during the fetal and neoinfantile period under 1 year of age. Although, more preliminary data and experience are required, patients older than 1 year that show a positive finding for GPC3 are considered to be appropriate candidates to receive the new immunotherapy using GPC3 peptide vaccination.[...]Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents&nb...
Source: European Journal of Pediatric Surgery - October 26, 2014 Category: Surgery Authors: Kinoshita, YoshiakiTanaka, SakuraSouzaki, RyotaMiyoshi, KinaKohashi, KenichiOda, YoshinaoNakatsura, TetsuyaTaguchi, Tomoaki Tags: Original Article Source Type: research

Outcome after Computer-Assisted (Robotic) Nissen Fundoplication in Children Measured as Pre- and Postoperative Acid Reducing and Asthma Medications Use
This study aims to report the clinical outcome of computer-assisted fundoplication (CAF) in children. Methods As our center changed policy to using computer-assisted surgery only, a prospectively studied cohort of 40 children underwent CAF, during the period from January 2006 through May 2013. The collected data include patient demographics and postoperative complications as well as medication, 24-hour pH measurements and DeMeester scores before and after surgery. Results In the studied group, the median percentage of the duration of the 24-hour pH 
Source: European Journal of Pediatric Surgery - October 26, 2014 Category: Surgery Authors: Granéli, ChristinaKockum, Christina ClementsonArnbjornsson, EinarAnderberg, Magnus Tags: Original Article Source Type: research

Ulcerative Ileitis after Proctocolectomy in Children: A Complication of Ulcerative Colitis or a Disease in Itself after Ileoanal Pullthrough?
Eur J Pediatr SurgDOI: 10.1055/s-0034-1394279Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - October 26, 2014 Category: Surgery Authors: Sánchez-Galán, AlbaAndres, Ane M.Fernández-Caamaño, BeatrizVilanova, AlejandraDominguez, EvaOrtiz, RubenPrieto, GerardoLopez-Santamaria, ManuelTovar, J. A. Tags: Erratum Source Type: research

One-Trocar–Assisted Pyeloplasty in Children: An 8-Year Single Institution Experience
Eur J Pediatr SurgDOI: 10.1055/s-0034-1394280Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - October 26, 2014 Category: Surgery Authors: Lima, MarioRuggeri, GiovanniMessina, PaoloTursini, StefanoDestro, FrancescaMogiatti, Mirella Tags: Erratum Source Type: research

Physiological Studies at 7 Years of Age in Children Born with Esophageal Atresia
Conclusion This study confirms a high prevalence of respiratory and esophageal morbidity. In terms of respiratory function, the high proportion with a spirometric abnormality indicated an associated developmental delay/dysfunction in the central airways, whereas the peripheral airways appeared to have normal function at this age. Tracheomalacia may explain the spirometric abnormalities, but this need to be studied in more detail.[...]Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents  |  Abstract  |  Full text (Source: European Journa...
Source: European Journal of Pediatric Surgery - October 10, 2014 Category: Surgery Authors: Olbers, JosefinGatzinsky, VladimirJönsson, LinusFriberg, Lars GöranAbrahamsson, KateSillén, UllaGustafsson, Per Tags: Original Article Source Type: research

Testicular Ascent after Laparoscopic Percutaneous Extraperitoneal Closure for Inguinal Hernias
Conclusion The postoperative testicular ascent should be carefully examined after the LPEC procedure in patients with pediatric inguinal hernias, especially in extremely low-birth-weight infants.[...]Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents  |  Abstract  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - October 4, 2014 Category: Surgery Authors: Shono, TakeshiIzaki, TomokoNakahori, RyouichiYoshimaru, Koichirou Tags: Original Article Source Type: research

Long-Term Results of Anderson–Hynes Pyeloplasty in Children: How Long Follow-Up is Necessary?
Conclusions Satisfactory diuretic renogram at 3 to 6 months after pyeloplasty with maintained renal function and stable hydronephrosis suggests no need for further follow-up and indicates no functional loss with time. More than 8% DRF fluctuation might be a significant cutoff for further intervention aiming nephron preservation.[...]Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents  |  Abstract  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - October 4, 2014 Category: Surgery Authors: Reis, Leonardo OliveiraIkari, OsamuZani, Emerson LuísMoretti, Tomás Bernardo CostaGugliotta, Antonio Tags: Original Article Source Type: research

Pitfalls in the Surgical Management of Undifferentiated Sarcoma of the Liver and Benefits of Preoperative Chemotherapy
Conclusion USL presents with painful mixed cystic and solid liver mass. If misdiagnosed and mistreated (enucleation or unroofing), the usual good outcome of this malignancy could be impaired. Preoperative chemotherapy is recommended.[...]Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents  |  Abstract  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - September 26, 2014 Category: Surgery Authors: Merli, LauraMussini, CharlotteGabor, FlaviuBranchereau, SophieMartelli, HélènePariente, DanièleGuérin, Florent Tags: Original Article Source Type: research

Epoprostenol Does Not Affect Mortality in Neonates with Congenital Diaphragmatic Hernia
Conclusion The discrepancy of results between the hospital and patient-level analyses suggests that the association of mortality and PGI in the patient-level analyses resulted from bias by indication. Hospital-level results provided no evidence of a benefit of PGI use on survival, but may have failed to detect a true benefit due to limited statistical power. Further use of PGI in this population should only be recommended after rigorous evaluation, such as a randomized controlled trial.[...]Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents  |  Abstract&...
Source: European Journal of Pediatric Surgery - September 13, 2014 Category: Surgery Authors: Skarda, David EmeryYoder, Bradley A.Anstadt, Erin ElizabethLally, Pamela A.Greene, TomMcFadden, MollyRollins, Michael D. Tags: Original Article Source Type: research

Microperc for Pediatric Nephrolithiasis: Technique in Valdivia-Modified Position
We present our initial experience in children using a modified technical approach. Methods After the retrograde positioning of a 5F catheter, a 4.85F metallic needle (1.9 mm) was used for direct percutaneous calyceal access under ultrasonographic and fluoroscopic guidance with the patient in supine Valdivia-modified position. Once a three-way connector was inserted to the needle, stone fragmentation was performed under direct vision using a 200 μm holmium:YAG laser fiber and a 0.9-mm high-resolution (10,000 pixels) optic flexible wire connected with the telescope, with intermittent saline infusion. The transu...
Source: European Journal of Pediatric Surgery - September 13, 2014 Category: Surgery Authors: Caione, PaoloDominicis, Mauro DeCollura, GiuseppeMatarazzo, EnnioNappo, Simona GerocarniCapozza, Nicola Tags: Original Article Source Type: research

Experience with Retroperitoneal Partial Nephrectomy in Bilateral Wilms Tumor
Conclusion Our experience demonstrates that the retroperitoneal approach is equivalent to the transabdominal technique with regards to intraoperative complications, lymph node dissection, and R0 resection. Advantages include less time to resumption of oral feeding, decreased risk of bowel injury, and isolation of urine leaks to the retroperitoneum. It should be considered a viable surgical option in the treatment of bilateral Wilms tumors.[...]Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents  |  Abstract  |  Full text (Source: Europ...
Source: European Journal of Pediatric Surgery - September 2, 2014 Category: Surgery Authors: Lim, Irene Isabel P.Honeyman, Joshua N.Fialkowski, Elizabeth A.Murphy, Jennifer M.Price, Anita P.Abramson, Sara J.Quaglia, Michael P. LaHeaton, Todd E. Tags: Original Article Source Type: research

Raman Spectroscopy in the Diagnosis of Ulcerative Colitis
Conclusions Raman spectroscopy can distinguish UC from normal colon tissue rapidly and accurately. This technology offers the possibility of real-time diagnosis as well as the ability to study changes in UC-afflicted colon tissue that do not appear histologically.[...]Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents  |  Abstract  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - August 30, 2014 Category: Surgery Authors: Veenstra, Michelle AnnePalyvoda, OlenaAlahwal, HazemJovanovski, MarkoReisner, Luke AnthonyKing, BradyPoulik, JanetKlein, Michael D. Tags: Original Article Source Type: research

Vacuum-Assisted Closure: A Novel Method of Managing Surgical Necrotizing Enterocolitis
Conclusion Our data demonstrate that use of the wound VAC is a safe approach in the management of premature infants with NEC requiring surgical intervention with outcomes comparable to standard surgical management. Use of the wound VAC may allow the establishment of bowel continuity and abdominal closure without the need for an ostomy. VAC therapy may also hasten the recovery of NEC patients with concomitant ACS by eliminating the compartment syndrome. Larger studies are required to confirm this theory.[...]Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents  |&nbs...
Source: European Journal of Pediatric Surgery - August 30, 2014 Category: Surgery Authors: Sea, StephanieMeckmongkol, TeerinMoront, Matthew L.Timmapuri, ShaheenPrasad, RajeevSchwartz, Marshall Z.Arthur, L Grier Tags: Original Article Source Type: research

Health Status and Quality of Life in Adult Biliary Atresia Patients Surviving with Their Native Livers
Conclusion Adult BA patients surviving with their native liver have similar HS and QOL as compared with their healthy peers. RAND-36 and WHOQOL-100 questionnaires are not interchangeable, but complementary to assess the patients' outcomes. The overall scores did not point to increased levels of anxiety and depression. However, on an individual level, three and six patients had a score above the cutoff of the HADS subscales demonstrating clinically relevant levels of anxiety and depression, respectively.[...]Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents  |&nbs...
Source: European Journal of Pediatric Surgery - August 30, 2014 Category: Surgery Authors: Lind, Robert C.de Vries, WillemienKeyzer, Claudia M. G.Peeters, Paul M. J. G.Verkade, Henkjan J.Hoekstra-Weebers, Josette E. H. M.van der Steeg, Alida F. W.Hulscher, Jan B. F. Tags: Original Article Source Type: research

Bladder Neck Closure in Children: Long-Term Results and Consequences
Conclusions BNC is an effective approach to incontinence when other procedures have failed. In the long term, the most frequent complications are those related with catheterizable stoma and stones. The high incidence report of a low fertility index and erectile dysfunction meant further study in a larger cohort.[...]Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents  |  Abstract  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - August 30, 2014 Category: Surgery Authors: Hernandez-Martin, SaraLopez-Pereira, PedroLopez-Fernandez, SergioOrtiz, RubénMarcos, MercedesLobato, RobertoMartinez-Urrutia, Maria JoseJaureguizar, Enrique Tags: Original Article Source Type: research

A Meta-Analysis of B-Mode Ultrasound, Doppler Ultrasound, and Computed Tomography to Diagnose Pediatric Ovarian Torsion
Conclusion This study found considerable variability of the reported sensitivities and specificities for the diagnosis of OT across all evaluated imaging modalities. Interestingly, B-mode US was the most sensitive and specific examination to detect OT. Some authors reported high diagnostic accuracy of DUS as well, but these findings have not been universally reproduced. CT had low overall sensitivity and is not recommended for the workup of suspected OT.[...]Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents  |  Abstract  |  Full text...
Source: European Journal of Pediatric Surgery - August 30, 2014 Category: Surgery Authors: Bronstein, Matthew E.Pandya, SamirSnyder, Christopher W.Shi, QiuhuMuensterer, Oliver J. Tags: Original Article Source Type: research

Thyroid Surgery in Children: Clinical Outcomes
Eur J Pediatr SurgDOI: 10.1055/s-0034-1384649 Aim The aim of this study was to review the outcomes of thyroid surgery in children operated for both benign and malignant conditions. Patients and Method Demography, clinical features, and surgical outcomes were noted retrospectively for operations performed during the last 23 years. Results were analyzed using Fisher exact test and Woolf (logit) method with p value 
Source: European Journal of Pediatric Surgery - August 21, 2014 Category: Surgery Authors: Sinha, C. K.Decoppi, PaoloPierro, AgostinoBrain, CarolineHindmarsh, PeterButler, GaryDattani, MehulSpoudeas, HelenKurzawinski, Tom R. Tags: Original Article Source Type: research

Problems during the Long-Term Follow-Up after Surgery for Pediatric Solid Malignancies
In this study, we analyzed the problems associated with the treatment of pediatric patients during the long-term follow-up after surgery. Patients and Methods A total of 64 patients with pediatric malignancies who underwent surgical treatment and were followed up for more than 5 years and who were older than 13 years of age were included in this study. The average age was 20.8 (13–33) years, and the follow-up ranged from 5 to 31 years (mean, 17.7 years). Twenty-one patients (32.3%) received high-dose chemotherapy (HDC) and nine (14.1%) received radiotherapy. Results In this study, 46 patients (7...
Source: European Journal of Pediatric Surgery - August 21, 2014 Category: Surgery Authors: Oue, TakaharuMiyoshi, YokoHashii, YoshikoUehara, ShuichiroUeno, TakehisaNara, KeigoUsui, NoriakiOzono, Keiichi Tags: Original Article Source Type: research

Tertiary Surgery for Complicated Repair of Esophageal Atresia
Conclusions When repeated complications appear after EA repair, radical surgical attitudes may be justified. If esophageal continuity cannot be reestablished, the native esophagus may have to be discarded and replaced. Many complications should be expected, but the end result can be good. These patients should be referred to centers with large experience in the management of this complex condition.[...]Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents  |  Abstract  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - August 21, 2014 Category: Surgery Authors: Ortiz, RubenGalán, Alba SánchezMartinez, LeopoldoDominguez, EvaHernández, FranciscoSantamaria, Manuel LopezTovar, Juan Antonio Tags: Original Article Source Type: research

Ulcerative Ileitis after Proctocolectomy in Children: A Complication of Ulcerative Colitis or a Disease in Itself after Ileoanal Pullthrough?
This study aims to review the cases of UI in our institution and to summarize their clinical features and management. A descriptive retrospective study of UI patients between 1990 and 2013 was conducted. Children with RPC and IAPP with clinical and pathological diagnosis of UI were included. Sociodemographic and clinical data, diagnostic, and therapeutic procedures were collected through medical records. UI was diagnosed in eight patients (six males) after RCP; four had UC, two had total colonic aganglionosis (TCA), and two had complex anorectal malformations (one cloacal exstrophy and one omphalopagus twin with bladder ex...
Source: European Journal of Pediatric Surgery - August 21, 2014 Category: Surgery Authors: Galán, Alba SánchezMoreno, Ane M. AndresCaamaño, Beatriz FernándezSánchez, Alejandra VilanovaDominguez, EvaOrtiz, RubenPrieto, GerardoSantamaria, Manuel LopezTovar, J. A. Tags: Original Article Source Type: research

Severe Tracheobronchial Injuries: Our Experience
Conclusion Conservative treatment with gentle respiratory support suffices in most traumatic cases of TBI. Infectious abscesses with involvement of adjacent structures sometimes require complex surgery and are life-threatening.[...]Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents  |  Abstract  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - August 21, 2014 Category: Surgery Authors: Dominguez, EvaTorre, Carlos De LaSánchez, Alejandra VilanovaHernandez, FranciscoOrtiz, RubenMoreno, Ane M AndresEncinas, Jose LuisVazquez, JuanSantamaria, Manuel LopezTovar, Juan Antonio Tags: Original Article Source Type: research

Nursing Intervention for Outpatient Rehabilitation in Pediatric Patients with Hirschsprung Disease after Colectomy
Eur J Pediatr SurgDOI: 10.1055/s-0034-1384650 Objective The present study was designed to evaluate the effectiveness of a nursing intervention program for outpatient rehabilitation of children with Hirschsprung-associated enterocolitis (HAEC) after radical colectomy for Hirschsprung disease (HD). Background Postoperative outcomes severely affect the quality of life in pediatric HD patients after operation. The improvement in defecation function is regarded as one of the most useful parameters to evaluate the quality of life in HD patients after radical intestinal resection. A close attention should al...
Source: European Journal of Pediatric Surgery - August 11, 2014 Category: Surgery Authors: Wang, HuiGuo, Xia-NeZhu, DanZhu, TianqiHu, Lu-HongFeng, Jie-Xiong Tags: Original Article Source Type: research

Perioperative Management after High-Dose Chemotherapy with Autologous or Allogeneic Hematopoietic Stem Cell Transplantation for Pediatric Solid Tumors
In this study, we reviewed our experience with surgery after HDC and autologous (auto) or allogeneic (allo) HSCT to elucidate the problems associated with this treatment and establish the optimum surgical management strategy. Patients and Methods We retrospectively reviewed the cases of 24 children with advanced malignancy treated with HDC and HSCT before tumor resection at our institution. The tumors included 18 neuroblastomas, 5 soft tissue sarcomas, 2 hepatoblastomas, and 1 Wilms tumor. The source of hematopoietic stem cells was auto-HSCT in 19 patients and allo-HSCT in 5 patients. To be able to undergo surge...
Source: European Journal of Pediatric Surgery - August 11, 2014 Category: Surgery Authors: Uehara, ShuichiroOue, TakaharuNakahata, KengoNara, KeigoUeno, TakehisaOwari, MitsuguUsui, NoriakiMiyamura, TakakoHashii, Yoshiko Tags: Original Article Source Type: research

Tumor-Associated Energy Homeostasis: Hepatoblastoma and Neuroblastoma Affect Glucose and Lipid Metabolism as well as Ghrelin, GLP-1, and PYY in Nude Rats
Eur J Pediatr SurgDOI: 10.1055/s-0034-1386640 Introduction The “metabolic competition” for nutrients between cancer cells and the patient has emerged as an important research area. For pediatric oncology, it remains unclear whether the neuroendokrine regulation of appetite by gastrointestinal hormones such as ghrelin “eat”, GLP-1 (glucagon-like peptide, “do not eat”), and PYY (peptide tyrosine–tyrosine, “do not eat”) is influenced by tumor growth. Material and Methods In a prospective randomized study, human hepatoblastoma (HB) and neuroblastoma (N...
Source: European Journal of Pediatric Surgery - August 11, 2014 Category: Surgery Authors: Till, HolgerSchlichting, NadineOberbach, Andreas Tags: Original Article Source Type: research

Lysyl Oxidase Expression Is Decreased in the Developing Diaphragm and Lungs of Nitrofen-Induced Congenital Diaphragmatic Hernia
Eur J Pediatr SurgDOI: 10.1055/s-0034-1386644 Introduction Malformation of the nonmuscular tissue components in congenital diaphragmatic hernia (CDH) is thought to underlie the diaphragmatic defect, causing intrathoracic herniation of abdominal viscera and thus disturbing normal lung development. It has been shown that diaphragmatic and pulmonary morphogeneses require the structural integrity of connective tissue, and developmental mutations that inhibit the formation of extracellular matrix (ECM) result in CDH with hypoplastic lungs. Lysyl oxidase (lox), an extracellular enzyme that catalyzes the cross-linking ...
Source: European Journal of Pediatric Surgery - August 11, 2014 Category: Surgery Authors: Takahashi, ToshiakiFriedmacher, FlorianTakahashi, HiromizuDaniel Hofmann, AlejandroPuri, Prem Tags: Original Article Source Type: research

Maximizing Lymph Node Retrieval during Surgical Resection of Wilms Tumor
Eur J Pediatr SurgDOI: 10.1055/s-0034-1386637 Introduction Sampling lymph nodes (LNs) is independently associated with decreased recurrence and improved survival for Wilms tumor (WT). Despite sampling, we noted cases where a few or no LNs were identified after resection of WT. We hypothesized fewer LNs were identified when submitted en bloc with the tumor, compared with when submitted separately. Patients/Materials and Methods We conducted a retrospective chart review from 2003 to 2012 of WT resection cases, examining the type of LN dissection, the specimens submitted to pathology, number of LNs evalu...
Source: European Journal of Pediatric Surgery - August 11, 2014 Category: Surgery Authors: Stewart, Camille LinickBruny, Jennifer Lynn Tags: Original Article Source Type: research