Laparoscopic Inguinal Hernia Repair in Infants and Children: State-of-the-Art Technique
This article reviews the latest updates of laparoscopic repair from the current evidence in the literature. Laparoscopic management of hernia in premature/small infants and hernia incarceration are also discussed here. [...] Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - November 22, 2017 Category: Surgery Authors: Chan, Ivy Hau-yee Tam, Paul Kwong-hang Tags: Review Article Source Type: research

Severe Trampoline Injuries: Incidence and Risk Factors in Children and Adolescents
This study aimed to illustrate these severe injuries and to find out their incidence and risk factors. Materials and Methods This is a population-based, prospective study in the Oulu region of Finland completed over 2 years (May 1, 2015 to April 31, 2017). All children (
Source: European Journal of Pediatric Surgery - November 22, 2017 Category: Surgery Authors: Korhonen, Linda Salokorpi, Niina Suo-Palosaari, Maria Pes älä, Juha Serlo, Willy Sinikumpu, Juha-Jaakko Tags: Original Article Source Type: research

Timing and Management of Inguinal Hernia in the Premature Baby
Eur J Pediatr Surg DOI: 10.1055/s-0037-1608802Inguinal hernias in children occur with a prevalence ranging from 3 to 5%. The likelihood of a symptomatic patent processus vaginalis is significantly higher in preterms, as reported by most series. As a consequence, inguinal hernia represents the most common condition requiring surgical repair in the neonate and preterm baby. Surgery aims at avoiding and preventing intestinal and gonadal lesions related to incarceration. Nonetheless, hernia repair is technically demanding, with a relatively high risk of complications including recurrence and testicular atrophy. This paper will...
Source: European Journal of Pediatric Surgery - November 15, 2017 Category: Surgery Authors: Pini Prato, Alessio Casaccia, Germana Arnoldi, Rossella Tags: Review Article Source Type: research

Femoral, Direct, and Rare Inguinal Hernias in Children —An Update
Eur J Pediatr Surg DOI: 10.1055/s-0037-1608684Pediatric surgeons deal with inguinal hernias on a regular basis. While most of these are straightforward in terms of diagnosis and therapy, occasionally what initially sounds like a routine case turns out to be a perplexing conundrum. This review discusses rare and unusual findings in the groin area that may mimic an indirect inguinal hernia, but are not. To provide good and effective care, pediatric surgeons should be readily familiar with the possible differential diagnosis of these entities, along with their specific management. In general, laparoscopy is one of the most us...
Source: European Journal of Pediatric Surgery - November 15, 2017 Category: Surgery Authors: G ödeke, Jan Muensterer, Oliver J. Tags: Review Article Source Type: research

A Review of the Incidence, Manifestation, Predisposing Factors, and Management of Recurrent Pediatric Inguinal Hernia
Eur J Pediatr Surg DOI: 10.1055/s-0037-1608675Recurrent pediatric inguinal hernia is relatively rare. In large series, the recurrence rates vary from 0.3 to 1.2%. In a university hospital with surgical service for a wide spectrum of sick pediatric patients, the real recurrence rate may be 3 to 6%. Recurrence manifests typically 6 months after first repair. Current evidence indicates that recurrence rates in open and laparoscopic repair are similar. Laparoscopic repairs are, however, still performed by a minority of skilled pediatric surgeons, whereas the majority of pediatric surgeons rely on open repair not least because ...
Source: European Journal of Pediatric Surgery - November 9, 2017 Category: Surgery Authors: Koivusalo, Antti I. Tags: Review Article Source Type: research

Laparoscopic Treatment of Hydrocele of the Canal of Nuck in Pediatric Patients
Conclusion Laparoscopic intracorporeal hydrocelectomy with high ligation is effective for HCN in pediatrics owing to its short operating time, excellent cosmesis, and no recurrence. [...] Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - October 26, 2017 Category: Surgery Authors: Lee, Sung Ryul Tags: Original Article Source Type: research

Surgical Experience and Learning Points in the Management of Foregut Duplication Cysts
Conclusion This retrospective study confirms the efficacy and safety of thoracoscopic surgery; important learning points were association of common wall with trachea in some superior mediastinal cysts and association of recurrent laryngeal nerve in cervical FDC. [...] Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - October 25, 2017 Category: Surgery Authors: Scarpa, Alberto Attilio Ram, Ashok Daya Soccorso, Giampiero Singh, Michael Parikh, Dakshesh Tags: Original Article Source Type: research

Social Morbidity in Relation to Bowel Functional Outcomes and Quality of Life in Anorectal Malformations and Hirschsprung's Disease
Conclusion Patients with severe ARMs and HD are at risk of social restrictions from impairment of bowel function despite contemporary surgical treatments. However, the QoL outcomes in adulthood may be more influenced by self-perceptions of illness formed from childhood than disease-specific factors. Strategies to reduce the psychological morbidity associated with these conditions that includes parental involvement from the outset may improve outcomes. [...] Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text...
Source: European Journal of Pediatric Surgery - October 23, 2017 Category: Surgery Authors: Kyrklund, Kristiina Neuvonen, Malla I. Pakarinen, Mikko P. Rintala, Risto J. Tags: Original Article Source Type: research

Pulmonary Hypertension in Patients with Congenital Diaphragmatic Hernia: Does Lung Size Matter?
Eur J Pediatr Surg DOI: 10.1055/s-0037-1607291 Purpose The relationship between pulmonary hypoplasia and pulmonary arterial hypertension (PHTN) in patients with congenital diaphragmatic hernia (CDH) remains ill-defined. We hypothesized that prenatal estimates of lung size would directly correlate with PHTN severity. Methods Infants with isolated CDH (born 2004–2015) at a single institution were included. Estimates of lung size included observed-to-expected LHR (o:eLHR) and %-predicted lung volumes (PPLV = observed/predicted volumes). The primary outcome was severity of PHTN (grade 0&ndas...
Source: European Journal of Pediatric Surgery - October 16, 2017 Category: Surgery Authors: Madenci, Arin L. Church, Joseph T. Gajarski, Robert J. Marchetti, Kathryn Klein, Edwin J. Coughlin, Megan A. Kreutzmann, Jeannie Treadwell, Marjorie Ladino-Torres, Maria Mychaliska, George B. Tags: Original Article Source Type: research

Centralization of Pediatric Surgery: European Perspective
Eur J Pediatr Surg 2017; 27: 387-387 DOI: 10.1055/s-0037-1606837 Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - October 13, 2017 Category: Surgery Authors: Rolle, Udo Tags: Editorial Source Type: research

Follow-up of Congenital Diaphragmatic Hernia: Need for Routinary Assessment of Acid Gastroesophageal Reflux with pH-metry
Conclusion We believe that a routine GER assessment should be performed in all CDH patients regardless the presence of symptoms. Level of Evidence Level II. [...] Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - October 11, 2017 Category: Surgery Authors: Zanini, Andrea Macchini, Francesco Farris, Giorgio Morandi, Anna Festa, Irene Brisighelli, Giulia Gentilino, Valerio Leva, Ernesto Tags: Original Article Source Type: research

Non-operative Management for Uncomplicated Appendicitis: An Option to Consider
Eur J Pediatr Surg DOI: 10.1055/s-0037-1607292 Aim The main goal of our study was to assess a 7 days long course of antibiotics for acute uncomplicated appendicitis. Materials and Methods From March 2014 to November 2015, all patients diagnosed with acute appendicitis have been considered to be treated by only antibiotics. Inclusion criteria included clinical (tenderness), biological (C-reactive protein [CRP]  6 mm). All patients were treated with intravenous amoxicillin and clavulanic acid (100 mg/kg/day) for 2 days (six doses). At the end of the treatment, clinical and paraclinical examinati...
Source: European Journal of Pediatric Surgery - October 10, 2017 Category: Surgery Authors: Abbo, Olivier Trabanino, Carmen Pinnagoda, Kalitha Ait Kaci, Amir Carfagna, Luana Mouttalib, Sofia Combelles, Sophie Vial, Julie Galinier, Philippe Tags: Original Article Source Type: research

Complicated Gastroschisis Is Associated with Greater Intestinal Morbidity than Gastroschisis or Intestinal Atresia Alone
Eur J Pediatr Surg DOI: 10.1055/s-0037-1607198 Aim of the Study The study aimed to compare outcomes and intestinal morbidity among complicated gastroschisis, isolated gastroschisis, and intestinal atresia. Methods In this retrospective observational single institution study, outcomes and intestinal morbidity were compared among gastroschisis complicated by intestinal atresia or perinatal bowel perforation, isolated gastroschisis, and isolated intestinal atresia. We included two cohorts; the first cohort included 68 consecutive patients with complicated gastroschisis (n = 9), isolated gastrosch...
Source: European Journal of Pediatric Surgery - October 4, 2017 Category: Surgery Authors: Mutanen, Annika Koivusalo, Antti Pakarinen, Mikko Tags: Original Article Source Type: research

Duhamel and Transanal Endorectal Pull-throughs for Hirschsprung' Disease: A Systematic Review and Meta-analysis
Conclusion The Duhamel pull-through seems to be associated with lower incidence of anastomotic stricture compared with TEPT. The effects of the two analyzed operative techniques on constipation and enterocolitis remain unclear. The quality of evidence supporting the above findings is suboptimal, indicating the need for prospective studies. [...] Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - September 28, 2017 Category: Surgery Authors: Seo, Shogo Miyake, Hiromu Hock, Alison Koike, Yuhki Yong, Chen Lee, Carol Li, Bo Pierro, Agostino Tags: Original Article Source Type: research

Close Examination of the Bar Removal Procedure: The Surgeons' Voice
Conclusion BRP complications are being underestimated and underreported. Publications do not reflect the real spectrum of complications, which includes life-threatening conditions, even death. Preoperative planning and preparation of the operating room should not be disregarded. [...] Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - September 28, 2017 Category: Surgery Authors: Alvarez-Garcia, Natalia Ardigo, Laura Bellia-Munzon, Gaston Martinez-Ferro, Marcelo Tags: Original Article Source Type: research

Surgical Emergencies in Intestinal Venous Malformations
Conclusion Intestinal VM can be challenging to diagnose in emergency situations, such as gastrointestinal situation or acute abdomen. The complications associated with it must be kept in mind, regardless of its low incidence. [...] Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - September 25, 2017 Category: Surgery Authors: Romo Mu ñoz, Martha Isabel Bueno, Alba De La Torre, Carlos Cerezo, Vanesa Nu ñez Rebolledo, Bryant Noriega Cervantes, Manuel Gomez Dore, Mariela Gomez, Javier Jimenez Santamaria, Manuel Lopez Martinez, Leopoldo Lopez-Gutierrez, Juan Carlos Tags: Original Article Source Type: research

A Single-Center Experience with Dynamic Compression Bracing for Children with Pectus Carinatum
Conclusion DCB has both early and lasting effects in the correction of PC with minimal complications. Predictive factors for successful resolution of the PC include increased duration of DCB and lower initial PIC. [...] Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - September 25, 2017 Category: Surgery Authors: Poola, Ashwini Suresh Pierce, Amy L. Orrick, Beth A. Peter, Shawn David St. Snyder, Charles L. Juang, David Aguayo, Pablo Fraser, Jason D. Holcomb, George W. Tags: Original Article Source Type: research

Surgical Implications for Diagnosis and Treatment of Intestinal Aspergillosis in Pediatric Patients with ALL
Conclusion Surgeons should be aware of surgical complications of intestinal aspergillosis in children with hematooncological diseases requiring exploration and resection. IA is a rare event and still difficult to diagnose due to unspecific abdominal symptoms. Thus, biopsy sampling is of utmost importance to ensure diagnosis, and resection of necrotic or perforated tissue should be attempted early. [...] Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - September 25, 2017 Category: Surgery Authors: Fischer, Janina Simon, Thorsten Hamprecht, Axel Hos, Nina M öricke, Anja Cernaianu, Grigore Tharun, Lars Gruhn, Bernd Plum, Georg D übbers, Martin Tags: Original Article Source Type: research

Dual versus Triple Antibiotics Regimen in Children with Perforated Acute Appendicitis
Conclusion Dual antibiotic therapy for perforated appendicitis is a cost-effective and efficient mode of therapy compared with triple-antibiotic's regimen. However, prospective studies are required to determine whether this policy is associated with higher rates of wound infections and change in antibiotic therapy. [...] Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - September 25, 2017 Category: Surgery Authors: Dreznik, Yael Feigin, Elad Samuk, Inbal Kravarusic, Dragan Baazov, Artur Levy, Itzhak Livni, Gilat Freud, Enrique Tags: Original Article Source Type: research

Tethered Cord and Anorectal Malformations: A Case Series
Conclusion The use of MRI is considered to complete the ARM screening in detecting TC. The multidisciplinary approach is crucial and helps in defining the management of patients. In fact, it is not clear how the features of ARM and TC affect each other. The selection of cases for surgery should take into account the critical elements. [...] Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - September 25, 2017 Category: Surgery Authors: Destro, Francesca Canazza, Lorena Meroni, Milena Selvaggio, Giorgio Parazzini, Cecilia Valentini, Laura Riccipetitoni, Giovanna Tags: Original Article Source Type: research

Outcomes of Esophageal Replacement: Gastric Pull-Up and Colonic Interposition Procedures
Conclusion The gastric pull-up and colonic interposition have comparable mortality and outcomes. The colonic interposition was associated with a higher rate of early septic complications, anastomotic strictures, and need for further surgery. [...] Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - September 25, 2017 Category: Surgery Authors: Bradshaw, Catherine Jane Sloan, Keren Morandi, Anna Lakshminarayanan, Bhanumathi Cox, Sharon Gail Millar, Alastair J. W. Numanoglu, Alp Lakhoo, Kokila Tags: Original Article Source Type: research

No Tissue Expression of KRAS or BRAF Mutations in 61 Adult Patients Treated for Esophageal Atresia in Early Childhood
Conclusion Despite the presence of histological findings indicating long-standing gastroesophageal reflux in 25%, as well as symptomatic gastroesophageal reflux in more than 40%, there was no detectable tissue expression of KRAS or BRAF mutations in this cohort of patients. [...] Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - September 5, 2017 Category: Surgery Authors: Dang, Kien Xuan Ho, Tho Sistonen, Saara Koivusalo, Antti Pakarinen, Mikko Rintala, Risto Stenman, Ulf-Hakan Orpana, Arto Stenman, Jakob Tags: Original Article Source Type: research

Erratum: Primary versus Staged Closure of Exomphalos Major: Cardiac Anomalies Do Not Affect Outcome
Eur J Pediatr Surg DOI: 10.1055/s-0037-1606226 Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - August 30, 2017 Category: Surgery Authors: Rees, Clare M. Tullie, Lucinda Pierro, Agostino Kiely, Edward Curry, Joe I. Cross, Kate Yates, Robert Eaton, Simon De Coppi, Paolo Tags: Erratum Source Type: research

Pediatric Intestinal Rehabilitation and Transplantation Registry: Initial Report from a European Collaborative Registry
Conclusion We present the web-based registry PIRAT and the first results of patients with IF registered from two European Centers. PIRAT could give the opportunity to create a dedicated international network (IF-net) to standardize, improve, and spread the therapeutic paths for the rare and heterogeneous condition of SBS-related IF. [...] Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - August 24, 2017 Category: Surgery Authors: Totonelli, Giorgia Tambucci, Roberto Boscarelli, Alessandro Hermans, Dominique Dall'Oglio, Luigi Diamanti, Antonella d'Aische, Aloys du Bois Pakarinen, Mikko Reding, Raymond Morini, Francesco Bagolan, Pietro Fusaro, Fabio Tags: Original Article Source Type: research

Postnatal Germ Cell Development in the Cryptorchid Testis: The Key to Explain Why Early Surgery Decreases the Risk of Malignancy
Conclusion Prepubertal ITGCN was rare and mostly seen in syndromic cryptorchidism. In nonsyndromic cryptorchidism PLAP-positive undifferentiated spermatogonial stem cells persisted in a significant proportion of nontreated undescended testes and they will be especially sensitive to long-lasting abnormally high temperature that may be the single most important cause facilitating the accumulation of mutations during cell replication and the development of ITGCN to be prevented by orchiopexy. [...] Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abs...
Source: European Journal of Pediatric Surgery - August 24, 2017 Category: Surgery Authors: Thorup, Jorgen Clasen-Linde, Erik Li, Ruili Reinhardt, Susanne Kvist, Kolja Vikraman, Jaya Southwell, Bridget R. Hutson, John M. Cortes, Dina Tags: Original Article Source Type: research

Histological and Biochemical Evaluation of Urethral Scar following Three Different Hypospadias Repairs: An Experimental Study in Rabbits
Eur J Pediatr Surg DOI: 10.1055/s-0037-1605347 Introduction Several urethroplasties have been employed in the surgical treatment of hypospadias. Neourethral strictures are among the most common postoperative complications that often require reoperation. Materials and Methods We created a hypospadias model in New Zealand white male rabbits through a hypospadias-like defect and acute repair. A total of 24 animals were randomly allocated into three groups: tubularized incised-plate urethroplasty (TIPU) group (8), perimeatal-based flap urethroplasty (Mathieu) group (8), onlay island flap urethroplasty (onlay) g...
Source: European Journal of Pediatric Surgery - August 24, 2017 Category: Surgery Authors: Tan, Xiao-Hui Liu, Xing Long, Chun-Lan Zhang, De-Ying Lin, Tao He, Da-Wei Wei, Guang-Hui Tags: Original Article Source Type: research

Protective Effects of Hypericum perforatum and Quercetin in a Rat Model of Ischemia/Reperfusion Injury of Testes
Conclusion Both Hp and quercetin have protective effects against I/R injury of the testes, but the protective effect of Hp was found to be stronger than that of quercetin. [...] Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - August 24, 2017 Category: Surgery Authors: Suzen, Alev Tekin, Leyla Erdemli, Mehmet Erman Erturk, Nazile Aksungur, Zeynep Aktas, Serdar Tags: Original Article Source Type: research

Understanding Experiences of Youth Growing Up with Anorectal Malformation or Hirschsprung's Disease to Inform Transition Care: A Qualitative In-Depth Interview Study
Conclusion Our model suggests that participants' understanding of bowel disease evolved over time with a “lightbulb” moment in preteens or early teens accompanied by increasing disease ownership and self-management. Clinicians should independently engage with patients in late childhood to address evolving emotional and information needs and encourage increasing autonomy. Future studies should explore communication approaches to meet transition needs of patients. [...] Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  ...
Source: European Journal of Pediatric Surgery - August 24, 2017 Category: Surgery Authors: Nah, Shireen Anne Ong, Caroline C. P. Lie, Desiree Marimuttu, Vicknesan Jeyan Hong, Julian Te-Lu, Yap Low, Yee Jacobsen, Anette Sundfor Tags: Original Article Source Type: research

Initiation of Enteral Feeding After Necrotizing Enterocolitis
Conclusion Initiating early enteral feeding, within 5 days of NEC diagnosis, is not associated with adverse outcomes, including NEC recurrence. In addition, catheter-related sepsis and post-NEC stricture rates were unchanged between early and delayed enteral feeding groups after NEC. However, the quality of the evidence from the review of literature is suboptimal. A further RCT is needed to confirm these results. [...] Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - August 24, 2017 Category: Surgery Authors: Hock, Alison Maria Chen, Yong Miyake, Hiromu Koike, Yuhki Seo, Shogo Pierro, Agostino Tags: Original Article Source Type: research

A Single-Center Experience with Very Low Birth Weight Infants and Focal Intestinal Perforation: Comparison of Primary Anastomosis versus Stoma Opening
Conclusion Both procedures appear to be safe. When possible, PA should be performed as it reduces the number of abdominal reinterventions. [...] Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - August 24, 2017 Category: Surgery Authors: Brisighelli, Giulia Consonni, Dario Macchini, Francesco Parente, Giovanni Zanini, Andrea Franzini, Stefania Colnaghi, Mariarosa Mosca, Fabio Leva, Ernesto Tags: Original Article Source Type: research

The Global Initiative for Children's Surgery: Optimal Resources for Improving Care
Conclusion The Optimal Resources document has been produced by surgical providers from LMICs who have the greatest insight into the needs and priorities in their population. The document will be refined further through online GICS Working Groups and the World Health Organization for broad application to ensure all children have timely access to safe surgical care. [...] Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - August 14, 2017 Category: Surgery Authors: Goodman, Laura F. St-Louis, Etienne Yousef, Yasmine Cheung, Maija Ure, Benno Ozgediz, Doruk Ameh, Emmanuel Adoyi Bickler, Stephen Poenaru, Dan Oldham, Keith Farmer, Diana Lakhoo, Kokila Tags: Original Article Source Type: research

Advantages of Cardiac Magnetic Resonance Imaging for Severe Pectus Excavatum Assessment in Children
Eur J Pediatr Surg DOI: 10.1055/s-0037-1604427 Aim Cardiac function can be impaired in patients with pectus excavatum (PE) due to anatomic and dynamic compression of the heart. Efforts for radiation dose reduction in imaging techniques have allowed cardiac magnetic resonance imaging (c-MRI) to play a major role in PE assessment. The aim of our study is to describe the findings of c-MRI 18 months after we changed the PE assessment protocol from chest computed tomography to c-MRI. Patients and Methods Since mid-2015 all patients with severe PE (suspected Haller's index > 3.2) were assessed wi...
Source: European Journal of Pediatric Surgery - July 31, 2017 Category: Surgery Authors: Dore, Mariela Triana Junco, Paloma Bret, Monserrat G ómez Cervantes, Manuel Mu ñoz Romo, Martha Jim énez Gómez, Javier P érez Vigara, Ana Parr ón Pajares, Manuel Luis Encinas, Jos é Hernandez, Francisco Martinez, Leopoldo L ópez Santamaría, Manue Tags: Original Article Source Type: research

Appendiceal Intussusception: A Diagnostic Challenge
Conclusion The mainstay of clinical presentation is intermittent abdominal pain while patients may be completely asymptomatic between attacks. Appendiceal intussusception may act as a leading point to ileocolic intussusception and is frequently concealed by it. The treatment is appendectomy. Both pediatric surgeons and radiologists should be aware of this occurrence to provide adequate management and avoid complications. [...] Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - July 25, 2017 Category: Surgery Authors: Samuk, Inbal Nica, Adriana Lakovski, Yaniv Freud, Enrique Tags: Original Article Source Type: research

Pitfalls in Diagnosis of Early-Onset Inflammatory Bowel Disease
Conclusion EoIBD poses a challenge due to ambiguous presentation and absence of specific diagnostic tests. Surgical evaluation is often needed and surgeons must be mindful of possible initial misdiagnosis, in addition to short- and long-term outcomes before deciding aggressive surgical measures as well as intestinal reconstruction. [...] Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - July 25, 2017 Category: Surgery Authors: Dore, Mariela Triana Junco, Paloma S ánchez Galán, Alba Prieto, Gerardo Ramos, Esther Mu ñoz Romo, Martha G ómez Cervantes, Manuel Hern ández, Francisco Mart ínez, Leopoldo L ópez Santamaría, Manuel Tags: Original Article Source Type: research

Long-Term Outcomes and Quality of Life in Patients after Soave Pull-Through Operation for Hirschsprung's Disease: An Observational Retrospective Study
This study aimed at investigating their long-term outcomes and quality of life (QoL) in comparison with controls. Patients and Methods Patients older than 5 years operated on for HD were interviewed to complete detailed questionnaires on bowel function. Patients without neurologic impairment were enrolled in a QoL survey to compare with controls matched for sex and age and selected randomly from the general population using sampling set in a ratio of four controls to one case of HD. Results In total, 53 operated patients were enrolled. Mean age of the patients was 16 ± 8 years, with 68%...
Source: European Journal of Pediatric Surgery - July 24, 2017 Category: Surgery Authors: Tran, Viet Quoc Mahler, Tania Dassonville, Martine Truong, Dinh Quang Robert, Annie Goyens, Philippe Steyaert, Henri Tags: Original Article Source Type: research

Surgical Health Needs of Minor Refugees in Germany: A Cross-Sectional Study
Conclusion Minor refugees have specific health-related problems that must be considered to ensure appropriate medical care. Many refugee children were victims of physical violence and many girls suffered genital mutilation. Vaccination status is unreliable; therefore, tetanus vaccination should always be considered when these patients seek pediatric surgical care. Tailored anticipatory guidance should be provided to this patient population. [...] Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: E...
Source: European Journal of Pediatric Surgery - July 18, 2017 Category: Surgery Authors: Loucas, Marios Loucas, Rafael Muensterer, Oliver J. Tags: Original Article Source Type: research

Pediatric Short Bowel Syndrome: Predicting Four-Year Outcome after Massive Neonatal Resection
Conclusions Survival of patients who have undergone neonatal massive small bowel resection has improved in recent years. Multidisciplinary strategies can improve the course of LD, but not the probability of weaning off PN, which seems to be strongly dependent on the anatomical profile of residual bowel. Therefore, the primary surgical approach should be as conservative as possible to gain even small amounts of intestinal length, which may be crucial in promoting intestinal adaptation. [...] Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract...
Source: European Journal of Pediatric Surgery - July 18, 2017 Category: Surgery Authors: Capriati, Teresa Giorgio, Daniela Fusaro, Fabio Candusso, Manila Schingo, Paolo Caldaro, Tamara Laureti, Francesca Elia, Domenica Diamanti, Antonella Tags: Original Article Source Type: research

Current Management of Congenital Pulmonary Airway Malformations: A “European Pediatric Surgeons' Association” Survey
Eur J Pediatr Surg DOI: 10.1055/s-0037-1604020 Aim To define current management of congenital pulmonary airway malformation (CPAM). Methods A total of 181 European Pediatric Surgeons' Association members (91% senior) from 48 countries completed an online questionnaire. Main Results Prenatal: 93% respondents work in centers with prenatal diagnosis facilities, and 27% in centers offering in utero surgery. Prenatal counseling is performed by 86% respondents, 22% of whom see>10 cases per year. Risk of single pre-/postnatal complications is deemed low (
Source: European Journal of Pediatric Surgery - July 14, 2017 Category: Surgery Authors: Morini, Francesco Zani, Augusto Conforti, Andrea van Heurn, Ernest Eaton, Simon Puri, Prem Rintala, Risto Lukac, Marija Kuebler, Joachim F. Friedmacher, Florian Wijnen, Rene Tovar, Juan Antonio Pierro, Agostino Bagolan, Pietro Tags: Original Article Source Type: research

Atropine Treatment for Hypertrophic Pyloric Stenosis: A Systematic Review and Meta-analysis
Eur J Pediatr Surg DOI: 10.1055/s-0037-1604116 Introduction Several authors have reported the use of atropine as an alternative treatment to pyloromyotomy in infants with hypertrophic pyloric stenosis (HPS). Our aims were to review the efficacy of atropine in treating HPS and to compare atropine therapy versus pyloromyotomy. Materials and Methods Using a defined search strategy (PubMed, MEDLINE, OVID, Embase, Cochrane databases), two investigators independently identified studies reporting the use of atropine for HPS. Case reports and opinion articles were excluded. Outcome measures included success rate, s...
Source: European Journal of Pediatric Surgery - July 12, 2017 Category: Surgery Authors: Lauriti, Giuseppe Cascini, Valentina Chiesa, Pierluigi Lelli Pierro, Agostino Zani, Augusto Tags: Review Article Source Type: research

Downregulated Elastin Microfibril Interfacer 1 Expression in the Pulmonary Vasculature of Experimental Congenital Diaphragmatic Hernia
Eur J Pediatr Surg DOI: 10.1055/s-0037-1604026 Aim Pulmonary hypertension (PH) is a severe complication of congenital diaphragmatic hernia (CDH). Transforming growth factor-β (TGFβ) signaling is suggested to be involved in PH development by regulating embryonic angiogenesis, cell proliferation, and cell differentiation. Altered TGFβ signaling has been demonstrated in experimental CDH lungs. Elastin microfibril interfacer 1 (Emilin-1) is an extracellular matrix glycoprotein expressed in endothelial and vascular smooth muscle cells and known to regulate TGFβ processing and arterial diameter. We de...
Source: European Journal of Pediatric Surgery - July 12, 2017 Category: Surgery Authors: Zimmer, Julia Takahashi, Toshiaki Hofmann, Alejandro D. Puri, Prem Tags: Original Article Source Type: research

Decreased Expression of Integrin Subunits α3, α6, and α8 in the Branching Airway Mesenchyme of Nitrofen-Induced Hypoplastic Lungs
Conclusions Decreased expression of Itga3, Itga6, and Itga8 in the pulmonary mesenchyme may lead to disruptions in airway branching morphogenesis, thus contributing to PH in the nitrofen-induced CDH model. [...] Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - July 12, 2017 Category: Surgery Authors: Takahashi, Toshiaki Friedmacher, Florian Zimmer, Julia Puri, Prem Tags: Original Article Source Type: research

Decreased Rac1 Cardiac Expression in Nitrofen-Induced Diaphragmatic Hernia
Eur J Pediatr Surg DOI: 10.1055/s-0037-1604025 Aim The high incidence of cardiac malformations in humans and animal models with congenital diaphragmatic hernia (CDH) is well known. The hypoplasia of left heart is common among fetuses with CDH and has been identified as a poor prognostic factor. However, the precise mechanisms underlying cardiac maldevelopment in CDH are not fully understood. Ras-related C3 botulinum toxin substrate 1 (Rac1) plays a key role in cardiomyocyte polarity and embryonic heart development. Deficiency of Rac1 is reported to impair elongation and cytoskeletal organization of cardiomyocytes, ...
Source: European Journal of Pediatric Surgery - July 6, 2017 Category: Surgery Authors: Nakamura, Hiroki Zimmer, Julia Puri, Prem Tags: Original Article Source Type: research

Management of Polypoid Gallbladder Lesions in Children: A Multicenter Study
Conclusion This report confirms appropriate use of a conservative approach with annual clinical and ultrasound follow-up for small-sized and isolated PLG in children given the absence of malignancy and potential vanishing entities. Surgical treatment should be considered in case of lesions larger than 10 mm in size or when they are associated with symptoms. [...] Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - July 2, 2017 Category: Surgery Authors: Ballouhey, Quentin Binet, Aur élien Varlet, Fran çois Baudry, Manon Dubois, R émi H éry, Géraldine Podevin, Guillaume Abbo, Olivier Arnaud, Alexis Barras, Marc Guerin, Francois Reinberg, Olivier Piolat, Christian Fourcade, Laurent Tags: Original Article Source Type: research

Parental Internet Use and Health Information Seeking Behavior Comparing Elective and Emergency Pediatric Surgical Situations
This study evaluates usage patterns of online health information in parents with children undergoing elective or emergency surgical procedures. Materials and Methods We prospectively surveyed parents of children admitted to our institution for common emergency (appendicectomy, abscess drainage, gonadal torsion) or elective (herniotomy, orchidopexy) operations between March and September 2016. Each completed an anonymized modification of a previously published survey comprising 19 questions on demographic data, Internet usage, and review of Internet resources. Chi-square tests were used for categorical data with p 
Source: European Journal of Pediatric Surgery - June 29, 2017 Category: Surgery Authors: Wong, Michael Kien Yee Sivasegaran, Daveraj Choo, Candy Suet Cheng Nah, Shireen Anne Tags: Original Article Source Type: research

Variceal Bleeds in Patients with Biliary Atresia
Conclusion One-fourth of the children diagnosed with BA experience variceal bleeds during follow-up. Most of these children are younger than 1 year and often already listed for transplantation. Major complications did not occur after variceal bleeding. [...] Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - June 28, 2017 Category: Surgery Authors: van Wessel, Daan B. Witt, Mauri Bax, Niels Verkade, Henkjan J. Scheenstra, Ren é de Kleine, Ruben H. Hulscher, Jan B. Tags: Original Article Source Type: research

Safeguarding Infant Brains: A Multidisciplinary Challenge —Results of a Survey, Update on Current Scientific Evidence, and Recommendations on How to Deal with Possible Anesthetic Drug Neurotoxicity
Conclusion The neurotoxicity question has reached the pediatric surgical community. Currently available scientific data do not support the theory of anesthetic drug-induced neurotoxicity in young children. Recent interdisciplinary clinical research focuses on neurodevelopmental outcome after surgery in neonates and infants. The European Safe Anesthesia For Every Tot initiative suggests focusing on proper conduct of anesthesia in children rather than on possible anesthetic drug neurotoxicity. [...] Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  A...
Source: European Journal of Pediatric Surgery - June 8, 2017 Category: Surgery Authors: Weber, Frank Vlot, John Wijnen, Rene Tags: Original Article Source Type: research

Modulation of the Early Host Response to Electrospun Polylactic Acid Matrices by Mesenchymal Stem Cells from the Amniotic Fluid
Conclusion Electrospun PLA matrices are a suitable substrate for short-term culture of AF-MSC. In rats, addition of AF-MSC to PLA matrices modulates the host response after subcutaneous implantation, yet without a difference in macrophage profile compared with control. [...] Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - May 31, 2017 Category: Surgery Authors: Lesage, Flore Roman, Sabiniano Pranpanus, Savitree Ospitalieri, Simona Zia, Silvia Jimenez, Julio MacNeil, Sheila Toelen, Jaan Deprest, Jan Tags: Original Article Source Type: research

Treatment of First-Time Perianal Abscess in Childhood, Balance Recurrence and Fistula Formation Rate with Medical Intervention
Eur J Pediatr Surg DOI: 10.1055/s-0037-1603092 Purpose Because of differences in therapy for first-time perianal abscess, a wide range of recurrences and/or development of fistula-in-ano (RF) rates have been reported. The indication for determining when surgical intervention is needed remains obscure and controversial. This retrospective study sought to compare outcomes of conservative treatment with those after incision and drainage (ID) to determine the optimal time for surgical intervention. Methods A total of 697 patients with first-time perianal abscess were included in this study. The median patient a...
Source: European Journal of Pediatric Surgery - May 31, 2017 Category: Surgery Authors: Gong, Zhenhua Han, Meilin Wu, Yibo Huang, Xiong Xu, Wei-Jue Lv, Zhibzo Tags: Original Article Source Type: research

The Young Pediatric Surgeon
Eur J Pediatr Surg 2017; 27: 212-213 DOI: 10.1055/s-0037-1603195 Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - May 31, 2017 Category: Surgery Authors: Dingemann, Carmen Tags: Editorial Source Type: research

Message for the Readers of European Journal of Pediatric Surgery
Eur J Pediatr Surg 2017; 27: 211-211 DOI: 10.1055/s-0037-1603452 Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - May 31, 2017 Category: Surgery Authors: Ure, Benno Brumfield, Graham Tags: Editorial Source Type: research