Cryptorchidism: An Update
Eur J Pediatr Surg 2016; 26: 389-389 DOI: 10.1055/s-0036-1592343 Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - October 10, 2016 Category: Surgery Authors: Thorup, Jorgen Tags: Editorial Source Type: research

Are Scores Reliable in Predicting the Need for Surgery and Mortality in Necrotizing Enterocolitis?
Conclusion In our cohort, the agreement between the predicted outcomes by scores and the real need for surgery and/or mortality was poor. There was a lack of clinical usefulness of the tested scores. We must continue to better identify parameters to help guide the management of these patients. [...] Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - October 5, 2016 Category: Surgery Authors: Arni, Delphine Karam, Oliver Vidal, Isabelle Rimensberger, Peter C. Hanquinet, Sylviane Wildhaber, Barbara E. Tags: Original Article Source Type: research

Rapid Response Team Activations in Pediatric Surgical Patients
Eur J Pediatr Surg DOI: 10.1055/s-0036-1593384 Introduction The rapid response team (RRT) is a multidisciplinary team who evaluates hospitalized patients for concerns of nonemergent clinical deterioration. RRT evaluations are mandatory for children whose Pediatric Early Warning System (PEWS) score (assessment of child's behavior, cardiovascular and respiratory status) is ≥4. We aimed to determine if there were differences in characteristics of RRT calls between children who were admitted primarily to either medical or surgical services. We hypothesized that RRT activations would be called for less severely ill c...
Source: European Journal of Pediatric Surgery - October 5, 2016 Category: Surgery Authors: Acker, Shannon N. Wathen, Beth Roosevelt, Genie E. Hill, Lauren R. S. Schubert, Anna Reese, Jenny Bensard, Denis D. Kulungowski, Ann M. Tags: Original Article Source Type: research

Surgical Treatment of Childhood Inflammatory Myofibroblastic Tumors
Conclusion IMT is a rare tumor of childhood with a spectrum of clinical findings because of variable localization. Surgical treatment is the first choice of treatment. Patients with residual mass and ALK positivity may require medical treatment. In our series, long-term survival of patients was favorable in patients with total resection. [...] Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - October 3, 2016 Category: Surgery Authors: Soyer, Tutku Talim, Beril Karnak, İbrahim Ekinci, Saniye Andiran, Fatih Çiftçi, Arbay Özden Orhan, Diclehan Aky üz, Canan Tanyel, Feridun Cahit Tags: Original Article Source Type: research

A New Era in Diagnostic Ultrasound, Superb Microvascular Imaging: Preliminary Results in Pediatric Hepato-Gastrointestinal Disorders
Conclusions Superb microvascular imaging is especially useful for depicting the microvascular flow and can aid in the diagnosis and treatment planning for pediatric patients with hepato-gastrointestinal disorders. [...] Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - October 3, 2016 Category: Surgery Authors: Ohno, Yasuharu Fujimoto, Tamotsu Shibata, Yukari Tags: Original Article Source Type: research

The Effect of Intramural Botulinum Toxin Injections on the Elongation of the Piglet Oesophagus Is Time Dependent
Conclusion Elongation of the piglet esophagus was significantly improved with a 2-hour waiting period after BTX-A injection. Injections with BTX-A could be useful in oesophageal atresia, where primary anastomosis is not possible. [...] Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - October 3, 2016 Category: Surgery Authors: Dibbern, Christian Bakholdt Rose, Morten Elleb æk, Mark Bremholm Qvist, Niels Tags: Original Article Source Type: research

Prof. Daniel H. Teitelbaum, MD (1957 –2016)
Eur J Pediatr Surg DOI: 10.1055/s-0036-1593467 Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - September 23, 2016 Category: Surgery Authors: Ure, Benno Tags: In Memoriam Source Type: research

Erratum: Transition of Patients with Esophageal Atresia to Adult Care: Results of a Transition-Specific Education Program
Eur J Pediatr Surg DOI: 10.1055/s-0036-1592311 Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - September 21, 2016 Category: Surgery Authors: Dingemann, Jens Szczepanski, R üdiger Ernst, Gundula Thyen, Ute Ure, Benno Goll, Melanie Menrath, Ingo Tags: Erratum Source Type: research

What Animal Models of Testicular Descent and Germ Cell Maturation Tell Us about the Mechanism in Humans
Eur J Pediatr Surg DOI: 10.1055/s-0036-1592196Testicular descent occurs in most mammals in two main steps that have different hormonal control and anatomical processes. The evolution of testicular descent reveals the same basic processes in humans and animals, with minor differences in timing and anatomy, especially the location of the scrotum and the processus vaginalis. Animal models are useful as they reveal some embryological processes that cannot be studies easily in humans, such as the potential role of the mammary line and the role of the genitofemoral nerve. Postnatal germ cell development is very similar in animal...
Source: European Journal of Pediatric Surgery - September 20, 2016 Category: Surgery Authors: Hutson, John Medwyn Li, Ruili Vikraman, Jaya Loebenstein, Moshe Tags: Review Article Source Type: research

Erratum: Procedure-Related Complications and Survival Following Fetoscopic Endotracheal Occlusion (FETO) for Severe Congenital Diaphragmatic Hernia: Systematic Review and Meta-Analysis in the FETO Era
Eur J Pediatr Surg DOI: 10.1055/s-0036-1592407 Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - September 20, 2016 Category: Surgery Authors: Araujo J únior, Edward Tonni, Gabriele Martins, Wellington P. Ruano, Rodrigo Tags: Erratum Source Type: research

Hormonal Aspects of the Pathogenesis and Treatment of Cryptorchidism
Eur J Pediatr Surg DOI: 10.1055/s-0036-1592415A normal functioning hypothalamic–pituitary–testicular axis is required for normal testicular descent. The percentage of cases that result from a disturbance in this axis remains controversial. Much has yet to be learnt about cryptorchidism, but is seems that the existence of A dark spermatogonia (Ad spermatogonia) is essential for later fertility. Bilateral cryptorchid patients have a high risk of later infertility, even though they undergo early surgery for cryptorchidism. It is possible today to distinguish—to a certain extent—between three different ...
Source: European Journal of Pediatric Surgery - September 19, 2016 Category: Surgery Authors: Cortes, Dina Holt, Rune de Knegt, Victoria Elizabeth Tags: Review Article Source Type: research

Genetic, Maternal, and Environmental Risk Factors for Cryptorchidism: An Update
Eur J Pediatr Surg DOI: 10.1055/s-0036-1592416Unilateral or bilateral cryptorchidism is an isolated anomaly in the majority of cases, with evidence to date suggesting that it is a complex disorder resulting from interactions between genetic and environmental factors. Population, family, and limited genome-wide association data suggest moderate genetic risk, multiple susceptibility loci, and a role for the maternal environment. Epidemiologic studies have identified low birth weight or intrauterine growth retardation as factors most strongly associated with cryptorchidism, with additional evidence suggesting that maternal sm...
Source: European Journal of Pediatric Surgery - September 19, 2016 Category: Surgery Authors: Barthold, Julia Spencer Reinhardt, Susanne Thorup, Jorgen Tags: Review Article Source Type: research

Systemic and Local Cytokine Profile in Biliary Atresia
Eur J Pediatr Surg DOI: 10.1055/s-0036-1592136 Purpose Systemic and local immune environments in human biliary atresia (BA) were analyzed. Methods Plasma concentrations of 19 inflammatory components in 16 preoperative BA patients (median age, 51 days), 13 normal controls (NCs) (44 days), and 15 cholestatic controls (CC) (23 days) were measured using flow cytometry, and compared according to post-Kasai outcomes in BA patients. Hepatic mRNA levels of representative helper T (Th) cell cytokines and forkhead box protein 3 (FoxP3) quantified by real-time reverse transcription polymerase chain reaction were compa...
Source: European Journal of Pediatric Surgery - September 16, 2016 Category: Surgery Authors: Saito, Takeshi Sakamoto, Akemi Hatano, Masahiko Iwai, Jun Higashimoto, Yasuyuki Yoshida, Hideo Tags: Original Article Source Type: research

Comments to Recent Guidelines on Undescended Testis
Eur J Pediatr Surg DOI: 10.1055/s-0036-1592195During the past couple of decades, our understanding of the treatment of undescended testis (UDT) has hugely expanded and it is still dynamically changing: new diagnostic tools are available, and experimental procedures are becoming a real-life treatment options. Our community needs to continuously update our guidelines. It is also our responsibility to build up, not a uniform, but a patient-oriented guideline which can provide information for both primary care providers and pediatric surgeons. Here, in Europe, we endeavor to change the different national guidelines to one comm...
Source: European Journal of Pediatric Surgery - September 15, 2016 Category: Surgery Authors: Kutasy, Balazs Thorup, Joergen M. Wester, Tomas Tags: Review Article Source Type: research

Surgical Management of the Undescended Testis: Recent Advances and Controversies
Eur J Pediatr Surg DOI: 10.1055/s-0036-1592197Undescended testis (UDT) is the most common disorder of sexual development in boys and affects 3.5% of male newborns. Although approximately half of newborn UDTs descend spontaneously, some boys develop an ascending testis later in childhood. Recent guideline recommendations advocate orchiopexy by 18 months of age to maximize potential for fertility and perhaps reduce the risk for testicular carcinoma in the future. For palpable testes, a standard inguinal approach is appropriate. However, the prescrotal approach is often effective for low inguinal testes and reduces surgical t...
Source: European Journal of Pediatric Surgery - September 15, 2016 Category: Surgery Authors: Elder, Jack S. Tags: Review Article Source Type: research

Positive Oct -3/4 and D2 –40 Immunohistochemical Expression in Germ Cells and Suspected Histology Pattern of Intratubular Germ Cell Neoplasia in Boys with Cryptorchidism Vanish after the Age of 2 Years
Conclusion This study is valuable in identifying the age-related change in Oct-3/4 or D2–40 immunopositive germ cells in seminiferous tubules. An ITGCN-like histological pattern in nonsyndromic cryptorchidism will vanish after the age of 3 years. Even when immunohistochemistry is applied, prepubertal ITGCN is so rarely demonstrated in cryptorchid testes, that it is not plausible that ITGCN generally originates during fetal development in cryptorchidism. [...] Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  F...
Source: European Journal of Pediatric Surgery - September 8, 2016 Category: Surgery Authors: Thorup, Jorgen Clasen-Linde, Erik Cortes, Dina Tags: Original Article Source Type: research

Surgical Management of Hiatal Hernia in Children with Asplenia Syndrome
Conclusions In patients with hiatal hernia, typical fundoplication is often difficult because most have concomitant brachyesophagus, microgastria, and hypoplasia of the esophageal hiatus. However, we should at least reduce the stomach to the abdominal cavity as early as possible to increase thoracic cavity volume and allow good feeding. Increasing the volume of the thoracic cavity thus makes Glenn and Fontan circulations more stable. Duodenal obstruction secondary to vascular anomalies is also common, so the anatomy in the area near the duodenum should be evaluated pre- and intraoperatively. [...] Georg Thieme Verlag ...
Source: European Journal of Pediatric Surgery - September 8, 2016 Category: Surgery Authors: Miyake, Hiromu Fukumoto, Koji Yamoto, Masaya Nouso, Hiroshi Kaneshiro, Masakatsu Koyama, Mariko Urushihara, Naoto Tags: Original Article Source Type: research

Metamizole for Postoperative Pain Therapy in Infants Younger than 1 Year
Conclusion Single intravenous doses of metamizole used for prevention or treatment of postoperative pain were safe in more than 300 infants younger than 1 year. The statistical probability of serious ADRs (e.g., hemodynamic, anaphylactic or respiratory reactions) was lower than 1%. The sample size and follow-up were not sufficient to detect agranulocytosis. [...] Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - September 5, 2016 Category: Surgery Authors: S ümpelmann, Robert Fieler, Melanie Eich, Christoph Becke, Karin Badelt, Gregor Leimk ühler, Klaus Dennhardt, Nils Tags: Original Article Source Type: research

Pneumoperitoneum in the Setting of Pneumatosis Intestinalis in Children: Is Surgery Always Indicated?
Conclusion Free air in the setting of PI may represent rupture of the gas cysts and not always transmural perforation. Surgery may not always be indicated and conservative management may suffice. A CT scan can be useful for excluding other intra-abdominal pathological findings and continued clinical assessment is essential. [...] Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - September 5, 2016 Category: Surgery Authors: Galea, Julie Burnand, Katherine M. Dawson, Fiona L. Sinha, Chandrasen K. Rex, Dean Okoye, Bruce O. Tags: Original Article Source Type: research

Long-Term Follow-Up after Treatment of Cryptorchidism
Eur J Pediatr Surg DOI: 10.1055/s-0036-1592138When considering long-term prognosis and results in adult age following treatment of cryptorchidism in childhood there are three main issues to be discussed: cosmetics, fertility, and malignancy. In the present review, the most recent research on the topics related to summaries of well-known knowledge on the field is presented.To some extent a smaller testis in a higher scrotal position than normal must be accepted as a fair cosmetic result after orchidopexy in childhood. The smaller testis size is related to the impaired fertility potential of the testis. In cases with atrophy...
Source: European Journal of Pediatric Surgery - September 2, 2016 Category: Surgery Authors: Thorup, Jorgen Cortes, Dina Tags: Review Article Source Type: research

Is Neuromuscular Blocker Necessary in Pediatric Patients Undergoing Laparoscopic Inguinal Hernia Repair with Percutaneous Internal Ring Suturing?
Conclusion sLMA is safe and suitable alternative to ETT and NMB is not necessary in general anesthesia with sLMA, pediatric patients undergoing laparoscopic hernia repair with PIRS. [...] Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - August 22, 2016 Category: Surgery Authors: Ahiskalioglu, Ali İnce, İlker Ahiskalioglu, Elif Oral Oral, Akgun Aksoy, Mehmet Yi ğiter, Murat Celikkaya, Mehmet Emin Salman, Ahmet Bedii Tags: Original Article Source Type: research

Esophageal Atresia: Future Directions for Research on the Digestive Tract
Eur J Pediatr Surg DOI: 10.1055/s-0036-1587330Esophageal atresia (EA) is a congenital malformation defined by the discontinuity of the esophagus occurring in 2.4 in 10,000 births. As survival rates are high, the significant medical morbidity became more relevant. Short-term and long-term morbidities involve the respiratory and gastrointestinal system in the majority of the patients. The impact of this morbidity seems large enough to inspire researchers to develop experimental animal models that may help understanding the pathogenesis and pathophysiology. These models can also be used to explore potential surgical therapies...
Source: European Journal of Pediatric Surgery - August 17, 2016 Category: Surgery Authors: Rayyan, Maissa Rommel, Nathalie Tack, Jan Deprest, Jan Allegaert, Karel Tags: Review Article Source Type: research

Renal Function Recovery after Nephrectomy or Nephron-Sparing Surgery in Children with Unilateral Renal Tumor
Conclusion The majority of children with URT and low baseline eGFR present with an impaired renal function recovery after nephrectomy and may benefit from NSS. Collaborative studies are needed to support present findings. [...] Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - August 17, 2016 Category: Surgery Authors: Cozzi, Denis A. Ceccanti, Silvia Cozzi, Francesco Tags: Original Article Source Type: research

Adult-Based Massive Transfusion Protocol Activation Criteria Do Not Work in Children
Conclusions Adult-based criteria for activation of MT perform poorly in the pediatric population. The use of SIPA modestly improves the sensitivity of the ABC score in children; however, the sensitivity and specificity of this score are still worse than when used in an adult population. This suggests the need to develop a new score that takes into account the low rate of penetrating trauma and positive FAST in the pediatric population. [...] Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Europe...
Source: European Journal of Pediatric Surgery - August 17, 2016 Category: Surgery Authors: Acker, Shannon N. Hall, Brianne Hill, Lauren Partrick, David A. Bensard, Denis D. Tags: Original Article Source Type: research

Procedure-Related Complications and Survival Following Fetoscopic Endotracheal Occlusion (FETO) for Severe Congenital Diaphragmatic Hernia: Systematic Review and Meta-Analysis in the FETO Era
This study aims to assess the procedure-related complications and survival following fetoscopic endotracheal occlusion (FETO) for severe congenital diaphragmatic hernia. Materials and Methods A systematic review and meta-analysis of PubMed and Scopus database searching for FETO procedure in severe CDH (lung-to-head ratio [LHR] 
Source: European Journal of Pediatric Surgery - August 14, 2016 Category: Surgery Authors: J únior, Edward Araujo Tonni, Gabriele Martins, Wellington P. Ruano, Rodrigo Tags: Review Article Source Type: research

Imbalance of NFATc2 and KV1.5 Expression in Rat Pulmonary Vasculature of Nitrofen-Induced Congenital Diaphragmatic Hernia
Eur J Pediatr Surg DOI: 10.1055/s-0036-1587589 Aim of the Study Nuclear factor of activated T-cell (NFATc2), a Ca2+/calcineurin-dependent transcription factor, is reported to be activated in human and animal pulmonary hypertension (PH). KV1.5, a voltage-gated K+ (KV) channel, is expressed in pulmonary artery smooth muscle cells (PASMC) and downregulated in PASMC in patients and animals with PH. Furthermore, activation of NFATc2 downregulates expression of KV1.5 channels, leading to excessive PASMC proliferation. The aim of this study was to investigate the pulmonary vascular expression of NFATc2 and KV1.5 in rats w...
Source: European Journal of Pediatric Surgery - August 14, 2016 Category: Surgery Authors: Zimmer, Julia Takahashi, Toshiaki Hofmann, Alejandro Daniel Puri, Prem Tags: Original Article Source Type: research

The Timing of Stoma Closure in Infants with Necrotizing Enterocolitis: A Systematic Review and Meta-Analysis
Conclusions This systematic review demonstrates that there is no difference between different timings for stoma closure in post-NEC infants. With the current supporting evidence, ESC seems to be as safe and feasible as LSC. Studies with a higher level of evidence are needed to confirm these conclusions. [...] Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - August 14, 2016 Category: Surgery Authors: Zani, Augusto Lauriti, Giuseppe Li, Qi Pierro, Agostino Tags: Original Article Source Type: research

Fibrillin-1 Expression Is Decreased in the Diaphragmatic Muscle Connective Tissue of Nitrofen-Induced Congenital Diaphragmatic Hernia
Eur J Pediatr Surg DOI: 10.1055/s-0036-1587586 Introduction Diaphragmatic morphogenesis depends on proper formation of muscle connective tissue (MCT) and underlying extracellular matrix (ECM). Fibrillin-1 is an essential ECM protein and crucial for the structural integrity of MCT in the developing diaphragm. Recently, mutations in the fibrillin-1 gene (FBN1) have been identified in cases of congenital diaphragmatic hernia (CDH), thus suggesting that alterations in FBN1 gene expression may lead to diaphragmatic defects. We designed this study to investigate the hypothesis that the diaphragmatic expression of fibrill...
Source: European Journal of Pediatric Surgery - August 14, 2016 Category: Surgery Authors: Takahashi, Toshiaki Friedmacher, Florian Zimmer, Julia Puri, Prem Tags: Original Article Source Type: research

Effect of Chelerythrine on Intestinal Cell Turnover following Intestinal Ischemia-Reperfusion Injury in a Rat Model
Conclusions Treatment with CHE inhibits programmed cell death and prevents intestinal mucosal damage following intestinal IR in a rat. [...] Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - August 14, 2016 Category: Surgery Authors: Sukhotnik, Igor Bitterman, Sivan Shahar, Yoav Ben Pollak, Yulia Bitterman, Nir Halabi, Salim Coran, Arnold G. Bitterman, Arie Tags: Original Article Source Type: research

The Minimally Invasive Repair of Pectus Excavatum Using a Subxiphoid Incision
Conclusion In this relatively large series of patients, the addition of a subxiphoid incision to the technique has allowed for safe passage of the bar across the mediastinum to avoid cardiac injury during the Nuss operation. [...] Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - August 14, 2016 Category: Surgery Authors: Gould, Joanna L. Sharp, Ronald J. Peter, Shawn David St. Snyder, Charles L. Juang, David Aguayo, Pablo Fraser, Jason D. Holcomb, George W. Tags: Original Article Source Type: research

Transition of Patients with Esophageal Atresia to Adult Care: Results of a Transition-Specific Education Program
Conclusions We identified a deficit of transition-specific knowledge in adolescents with a history of EA. These patients benefit from a transition-specific education program. Thus, the transition to adult care may be facilitated resulting in an improved long-term care of patients with EA. [...] Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - August 14, 2016 Category: Surgery Authors: Dingemann, Jens Szczepanski, R üdiger Ernst, Gundula Thyen, Ute Ure, Benno Goll, Melanie Menrath, Ingo Tags: Original Article Source Type: research

Regenerative Capacity of the Enteric Nervous System after Ileoileal Anastomoses in a Rat Model
Eur J Pediatr SurgDOI: 10.1055/s-0036-1586200 Purpose The aim of the study was to investigate the regeneration and migration of neuronal progenitor cells of the enteric nervous system during wound healing after intestinal anastomosis in the rat ileum. Methods Experiments were performed in a rat model of ileoileal anastomosis. Rats were humanely killed on day 2 or day 10 after anastomosis, and the anastomotic region was compared with ileum of healthy rats. Immunofluorescent staining was performed with protein gene product 9.5, nestin, and S100 antibodies. Ganglia of the anastomotic region in both the m...
Source: European Journal of Pediatric Surgery - July 27, 2016 Category: Surgery Authors: Pfeifle, Viktoria Amanda Gros, Stephanie J. Frongia, Giovanni Sch äfer, Karl-Herbert Holland-Cunz, Stefan Tags: Original Article Source Type: research

Laparoscopic Repair for Perforated Peptic Ulcer in Children
Conclusion Laparoscopic repair is safe and feasible for PPU and should be the gold standard for treatment of PPU in children.[...]Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents  |  Abstract  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - July 25, 2016 Category: Surgery Authors: Reusens, Helena Dassonville, Martine Steyaert, Henri Tags: Original Article Source Type: research

Analgesia and Sedation Protocol for Mechanically Ventilated Postsurgical Children Reduces Benzodiazepines and Withdrawal Symptoms —But Not in All Patients
Eur J Pediatr SurgDOI: 10.1055/s-0036-1586202 Background We demonstrated recently that the implementation of a nurse-driven analgesia and sedation protocol (pediatric analgesia and sedation protocol [pASP]) for mechanically ventilated nonpostsurgical patients reduces the total dose of benzodiazepines and the withdrawal symptoms significantly. It has not been investigated if these results can also be expected in the group of patients undergoing surgery. Objectives To evaluate the effects of the pASP in mechanically ventilated postsurgical children regarding drug dosage, duration of mechanical ventilat...
Source: European Journal of Pediatric Surgery - July 25, 2016 Category: Surgery Authors: Neunhoeffer, Felix Seitz, Guido Schmidt, Andreas Renk, Hanna Kumpf, Matthias Fideler, Frank Esslinger, Martin Gerbig, Ines Fuchs, J örg Hofbeck, Michael Tags: Original Article Source Type: research

Diagnosis and Treatment of Pediatric Necrotizing Fasciitis: A Systematic Review of the Literature
Conclusions Pediatric NF has distinguishing features that differ from adult NF. Knowledge of these details should increase early diagnosis and improve treatment.[...]Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents  |  Abstract  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - July 5, 2016 Category: Surgery Authors: Zundel, SabineLemaréchal, AngelaKaiser, PhilippSzavay, Philipp Tags: Review Article Source Type: research

Pelvic Angiography for Trauma in Children: A Rare but Useful Adjunct
Conclusions Pelvic angiography is a useful treatment option in pediatric patients with pelvic fractures and clinical evidence of ongoing blood loss without other explanation. Contrast extravasation on CT scan alone may not require further intervention.[...]Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents  |  Abstract  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - July 1, 2016 Category: Surgery Authors: Gonzalez, Katherine W.Dalton, Brian G.Kerisey, Michael C.Aguayo, PabloJuang, David Tags: Original Article Source Type: research

Prolonged Use of Proton Pump Inhibitors as Stricture Prophylaxis in Infants with Reconstructed Esophageal Atresia
Conclusion Development of AS in the first year after reconstruction of EA was not reduced by prolonged PPI prophylaxis (12 vs. 3 months), but initial balloon dilation procedures were performed later in infants who were treated longer.[...]Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents  |  Abstract  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - May 23, 2016 Category: Surgery Authors: Stenström, PernillaAnderberg, MagnusBörjesson, AnnaArnbjornsson, Einar Tags: Original Article Source Type: research

Hirschsprung Disease: Critical Evaluation of the Global Research Architecture Employing Scientometrics and Density-Equalizing Mapping
Conclusion We conclude that the field of HD is constantly progressing. The importance of international cooperation in the scientific community is continuously growing.[...]Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents  |  Abstract  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - May 13, 2016 Category: Surgery Authors: Schöffel, NormanGfroerer, StefanRolle, UdoBendels, Michael H. K.Klingelhöfer, DorisGroneberg-Kloft, Beatrix Tags: Original Article Source Type: research

Intraperitoneal Local Anesthetic in Pediatric Surgery: A Systematic Review
Conclusions IPLA appears promising in pediatric surgery. The high absorptive capacity of the peritoneum and high peritoneal surface area to volume ratio in children presents a dose limitation. In comparison to adult surgery, IPLA has been understudied in pediatric surgery.[...]Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents  |  Abstract  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - April 22, 2016 Category: Surgery Authors: Hamill, James K.Rahiri, Jamie-LeeLiley, AndrewHill, Andrew G. Tags: Review Article Source Type: research

Venous Malformation and Localized Intravascular Coagulopathy in Children
This study aims to determine the prevalence of LIC in children with VM and associated risk factors. Methods Patients younger than 18 years with VM from 2010 to 2014 were reviewed. Diagnosis was confirmed by Doppler ultrasound and/or magnetic resonance imaging. Demographics data and VM characteristics including volume, site, extension, painful symptoms, and palpable phleboliths were studied. Plasma D-dimer level of greater than 500 ng/mL was considered as abnormal. Results Total 24 children were included, of whom 8 were boys. Median age of presentation was 9 months (range: 0–12 years). Head-and-n...
Source: European Journal of Pediatric Surgery - April 18, 2016 Category: Surgery Authors: Hung, Judy W. S.Leung, Michael W. Y.Liu, Clarence S. W.Fung, Dickson H. S.Poon, W. L.Yam, Felix S. D.Leung, Yvonne C. L.Chung, Kenneth Lap YanTang, Paula M. Y.Chao, Nicholas S. Y.Liu, Kelvin K. W. Tags: Original Article Source Type: research

Computed Tomographic Study of the Pediatric Diaphragmatic Growth: Application to the Treatment of Congenital Diaphragmatic Hernia
Conclusion The treatment of CDH with large defect remains a challenge because of the high incidence of hernia recurrence probably due to prosthesis defect; thus it is important to estimate the diaphragmatic surface precisely. We aim to develop a prosthesis material that can be commonly used and found a mean diaphragmatic growth factor of approximately 4 to 5 from early childhood to adolescence.[...]Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents  |  Abstract  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - April 11, 2016 Category: Surgery Authors: Schneider, AnneKoob, MeriamSananes, NicolasSenger, BernardHemmerlé, JosephBecmeur, Francois Tags: Original Article Source Type: research

Complex Fluid Collection on Abdominal Ultrasound Indicates Need for Surgery in Neonates with Necrotizing Enterocolitis
Conclusion Complex fluid collection shown with abdominal ultrasound appears to be strongly correlated to the need for surgery in newborn infants with severe NEC.[...]Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents  |  Abstract  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - March 28, 2016 Category: Surgery Authors: Palleri, ElenaKaiser, SylvieWester, TomasArnell, HenrikBartocci, Marco Tags: Original Article Source Type: research

Pneumonostomy in the Surgical Management of Hydatid Cyst of the Lung
Conclusion Pneumonostomy is a safe and effective technique for dealing with the residual cavity in large complicated cysts and bilateral HCL.[...]Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents  |  Abstract  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - March 28, 2016 Category: Surgery Authors: Jehangir, SusanKurian, Jujju JacobJacob, Tarun JohnGurram, Grace MaryThomas, Reju JosephMathai, JohnKarl, Sampath Tags: Original Article Source Type: research

Video-Assisted Needle Core Biopsy in Children Affected by Neuroblastoma: A Novel Combined Technique
Conclusions The video-assisted needle-core biopsy combines minimally invasive surgery several advantages with the possibility to obtain multiple samples in different regions with minimal tumor exposition and low complication rate.[...]Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents  |  Abstract  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - March 28, 2016 Category: Surgery Authors: Avanzini, StefanoFaticato, Maria GraziaSementa, Angela RitaGranata, ClaudioMartucciello, GiuseppePio, LucaPrato, Alessio PiniGaraventa, AlbertoBisio, GiovanniMontobbio, GiovanniBuffa, PieroMattioli, Girolamo Tags: Original Article Source Type: research

Prenatal and Postnatal Clinical Course of an Urachus Identified as an Allantoic Cyst in the Umbilical Cord
Conclusion The presence of an urachus identified as an allantoic cyst in the umbilical cord is frequently associated with spontaneous rupture during the prenatal period, resulting in a patent urachus after birth that requires surgical intervention.[...]Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents  |  Abstract  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - March 16, 2016 Category: Surgery Authors: Umeda, SatoshiUsui, NoriakiKanagawa, TakeshiYamamichi, TakuNara, KeigoUeno, TakehisaOwari, MitsuguUehara, ShuichiroOue, TakaharuKimura, TadashiOkuyama, Hiroomi Tags: Original Article Source Type: research

Long-Term Follow-Up of Testicular Microlithiasis in Children and Adolescents: Multicenter Prospective Cohort Study of the Italian Society of Pediatric Urology
Conclusion TM is a controversial entity, often associated with several inguinogenital features, which rarely can recover. Testicular malignancy, although present in TM, has not proven definitively associated to microliths. Proper counseling, yearly ultrasound, and self-examination are long-term recommended.[...]Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents  |  Abstract  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - March 10, 2016 Category: Surgery Authors: Marte, AntonioPintozzi, LuciaCretì, GiuseppeChiesa, Pierluigi LelliRenzo, Dacia DiGasparella, MarcoMaggio, Giovanni DiBagnara, VincenzoMerlini, EmilioTadini, BarbaraCaldarulo, EustachioSangiorgio, LucianoBattaglino, GianfrancoNappo, Simona GerocarniCaion Tags: Original Article Source Type: research

Prof. Pascal de Lagausie (1960–2016)
Eur J Pediatr SurgDOI: 10.1055/s-0036-1579683Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - February 24, 2016 Category: Surgery Authors: Guys, Jean-MichelUre, Benno Tags: In Memoriam Source Type: research

Laparoscopic Ureterolithotomy in Children: With and Without Stent — Initial Tertiary Care Center Experience with More Than 1-Year Follow-Up
Eur J Pediatr SurgDOI: 10.1055/s-0036-1572551 Background The purpose of our study was to assess the safety and feasibility of transperitoneal laparoscopic ureterolithotomy (LU) in children with ureteric stones with and without a stent. Method Impacted ureteric stone of size ≥ 1.5 cm or ureteric stones that were refractory to shock wave lithotripsy (SWL)/ureteroscopy (URS) were considered for LU. From December 2009 to April 2012, 50 cases of LU were performed with a stent being placed. From May 2012 onward we now perform stentless LU and till now we have done approximately 64 such type...
Source: European Journal of Pediatric Surgery - February 15, 2016 Category: Surgery Authors: Srivastava, AlokDhayal, Ishwar RamRai, Priyanka Tags: Original Article Source Type: research

Factors Associated with Abnormal Imaging and Infection Recurrence after a First Febrile Urinary Tract Infection in Children
Conclusion All children younger than 3 years with first febrile UTI should undergo ultrasonography. Thereafter, patients with no predictive factors for vesicoureteral reflux may be followed up without further imaging. A non–E. coli infection is associated with reflux and infection recurrence.[...]Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents  |  Abstract  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - February 8, 2016 Category: Surgery Authors: Ristola, Marko TapaniLöyttyniemi, EliisaHurme, Timo Tags: Original Article Source Type: research

European Paediatric Surgeons' Association (EUPSA)
Eur J Pediatr Surg 2016; 26: 001-001DOI: 10.1055/s-0035-1571258Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - January 22, 2016 Category: Surgery Authors: Wester, TomasUre, Benno Tags: Editorial Source Type: research