Stage 4S Neuroblastoma: What Are the Outcomes? A Systematic Review of Published Studies
Conclusion There is a significant mortality observed in stage 4S/MS neuroblastoma infants with a dismal outcome observed in those patients with MYCN amplification and 1p/11q deletion. Those patients suitably amenable for conservative management or surgery to excise the primary tumor carry the best prognosis. [...] Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - September 14, 2020 Category: Surgery Authors: Raitio, Arimatias Rice, Michael J. Mullassery, Dhanya Losty, Paul D. Tags: Review Article Source Type: research

Oral Health Status among Children with Repaired Esophageal Atresia
Conclusion Regular dental counseling adopting the multidisciplinary team approach for patients with EA is necessary to ensure better general and oral health. [...] Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - September 14, 2020 Category: Surgery Authors: Ozsin-Ozler, Cansu Turgut, Melek D. Uzamis-Tekcicek, Meryem Soyer, Tutku Tags: Original Article Source Type: research

Ileal Neoappendicostomy in the Treatment of Fecal Incontinence in Children
Conclusion Ileal neoappendicostomy may be an alternative to ACE in children with severe and medically intractable constipation and or/and fecal incontinence where the appendix is missing or not available. [...] Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - September 14, 2020 Category: Surgery Authors: Abildgaaard, Helle Attermann Elleb æk, Mark Bremholm Rawashdeh, Yazan F. Qvist, Niels Tags: Original Article Source Type: research

Surgical Management of Rectal Prolapse in Infants and Children
Eur J Pediatr Surg DOI: 10.1055/s-0040-1716725The surgical management of children with rectal prolapse is wide ranging and without consensus within the pediatric surgical community. While the majority of rectal prolapse in infants and children resolves spontaneously or with the medical management of constipation, a small but significant subset of patients may require intervention for persistent symptoms. In this review, we discuss the etiology and pathophysiology of rectal prolapse in both infants and children, options for medical management, described interventions and surgical options and their outcomes, and future avenu...
Source: European Journal of Pediatric Surgery - September 12, 2020 Category: Surgery Authors: Saadai, Payam Trappey, A. Francois Langer, Jacob L. Tags: Review Article Source Type: research

Anal Fissure in Children
Eur J Pediatr Surg DOI: 10.1055/s-0040-1716723Anal fissure is a common clinical problem in children and is defined as a longitudinal tear in the anal canal. The typical presentation is painful defecation and rectal bleeding. The etiology of anal fissure is unknown, but passage of hard stools and increased internal anal sphincter pressure are considered important factors. The treatment is oriented to relieve the spasm of the internal anal sphincter, which prevents healing of the fissure. Conservative management with stool softeners, topical analgesics, and sitz baths is recommended as first-choice therapy. Surgical treatmen...
Source: European Journal of Pediatric Surgery - September 12, 2020 Category: Surgery Authors: Patkova, Barbora Wester, Tomas Tags: Review Article Source Type: research

Evaluation of Bowel Function, Urinary Tract Function, and Quality of Life after Transanal Endorectal Pull-Through Surgery for Hirschsprung's Disease
Conclusion According to Clavien-Dindo, short-term postoperative complications occurred in 20% of the patients. Impaired bowel function persists throughout childhood for most HSCR patients. The prevalence of LUTS and QoL is not affected in HSCR patients compared with controls. [...] Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - September 1, 2020 Category: Surgery Authors: Bystr öm, Cornelia Östlund, Sanna Hoff, Nils Wester, Tomas Granstr öm, Anna Löf Tags: Original Article Source Type: research

Changes in Incidence and Management of Acute Appendicitis in Children —A Population-Based Study in the Period 2000–2015
Conclusion In accordance with other recent studies from Western countries, we found significant changes in the incidence of acute appendicitis including a decline in all age groups except those below 5 years of age, a shift toward laparoscopic appendectomy, and decreasing time spent in the hospital during the years 2000 to 2015. [...] Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - August 30, 2020 Category: Surgery Authors: Hansen, Grith Laerkholm Kleif, Jakob Jakobsen, Christian Paerregaard, Anders Tags: Original Article Source Type: research

Pbx1, Meis1, and Runx1 Expression Is Decreased in the Diaphragmatic and Pulmonary Mesenchyme of Rats with Nitrofen-Induced Congenital Diaphragmatic Hernia
Conclusion Decreased Pbx1, Meis1, and Runx1 expression during diaphragmatic development and lung branching morphogenesis may reduce mesenchymal cell proliferation, causing malformed PPFs and disrupted airway branching, thus leading to diaphragmatic defects and PH in the nitrofen-induced CDH model. [...] Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - August 29, 2020 Category: Surgery Authors: Takahashi, Toshiaki Friedmacher, Florian Zimmer, Julia Puri, Prem Tags: Original Article Source Type: research

Effect of Feeding Strategies on the Development of Fulminant Necrotizing Enterocolitis
Conclusion Among premature neonates with NEC, reaching full volume feedings was associated with a nearly 70-fold increased risk of F-NEC. Assuming it was possible to predict an infant's development of NEC, alternative feeding regimens might reduce the risk of F-NEC in this population. [...] Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - August 29, 2020 Category: Surgery Authors: Hartman, Heather A. Pennell, Christopher Aronoff, Stephen Arthur, L. Grier Tags: Original Article Source Type: research

Implication of Image-Defined Risk Factors for the Extent of Surgical Resection and Clinical Outcome in Patients with Pelvic Neuroblastoma
Conclusion Our results indicate on a preliminary level the importance of IDRF as a prognostic tool for surgical removal of pelvic NB. [...] Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - August 29, 2020 Category: Surgery Authors: Froeba-Pohl, Alexandra von Schweinitz, Dietrich Muehling, Jakob Paolini, Marco Hubertus, Jochen Tags: Original Article Source Type: research

Pediatric Surgery during the COVID-19 Pandemic: An International Survey of Current Practice
Conclusion Service provision has been severely affected by COVID-19 leading to an inevitable increase in untreated surgical pathology. Better understanding of extrapulmonary infectivity, the risk of asymptomatic carriage in children, and the reliability of testing for surgical scenarios may allow appropriate use of conventional surgery, including laparoscopy and endoscopy, and rational development of the novel care pathways needed during the pandemic. [...] Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - August 25, 2020 Category: Surgery Authors: Nasher, Omar Sutcliffe, Jonathan Richard Stewart, Richard James Tags: Original Article Source Type: research

A Standardized Protocol for Nonoperative Management of Complicated Appendicitis in Children Reduces Resource Utilization
Conclusion Implementing an SP for treating complicated appendicitis nonoperatively reduced resource utilization without negatively affecting clinical outcomes. [...] Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - August 22, 2020 Category: Surgery Authors: Pennell, Christopher Meckmongkol, Teerin Prasad, Rajeev Ciullo, Sean Arthur III, Lindsay Grier Lindholm, Erika Grewal, Harsh Tags: Original Article Source Type: research

Ethical Publication Standards in Articles Reporting on Novel Surgical Methods: Analysis of Three Pediatric Surgical Journals
Conclusion Adherence to ethical publication principles in pediatric surgery has improved over the last years but is still lacking in many publications. When implementing new methods, prior ethical approval and informed consent and their documentation are mandatory, specifically in the light of potential hazard to patients. [...] Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - August 19, 2020 Category: Surgery Authors: Uecker, Marie Ure, Benno M. Dingemann, Jens Tags: Original Article Source Type: research

Choledochal Cysts Resected during Childhood Show No Mutations of KRAS and BRAF as Early Markers of Malignancy in Cholangiocytes
Conclusion In our series, chronic inflammatory changes were frequently present in CDC of infants and children. However, the lack of KRAS and BRAF mutations suggests that no malignant changes have been initiated in this group of European patients undergoing early resection. [...] Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - August 19, 2020 Category: Surgery Authors: Uecker, Marie Lehmann, Ulrich Braubach, Peter Schukfeh, Nagoud Madadi-Sanjani, Omid Ure, Benno M. Petersen, Claus Kuebler, Joachim F. Tags: Original Article Source Type: research

Application of Machine Learning Techniques for Enuresis Prediction in Children
Conclusion MLT might provide a faster and easier evaluation process for studies on enuresis with a large dataset. The model in this study may suggest that selected variables with high feature values could be preferred with priority in any screening studies for enuresis. MLT may prevent clinical errors due to human cognitive biases and may help the physicians to be proactive in diagnosis and treatment of enuresis. [...] Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - August 19, 2020 Category: Surgery Authors: Tokar, Baran Baskaya, Mukaddes Celik, Ozer Cemrek, Fatih Acikgoz, Ayfer Tags: Original Article Source Type: research