Evaluation of the in vitro performance of generic and original adapalene gel
Conclusions: The factors mentioned above should be considered when developing and manufacturing generic adapalene gels, and the application of TCS in the evaluation of generic topical drugs was advanced. Additionally, our research revealed some discrepancies from USP < 1724>, which could be valuable information for the revision.PMID:37847563 | DOI:10.1080/03639045.2023.2271966 (Source: Drug Development and Industrial Pharmacy)
Source: Drug Development and Industrial Pharmacy - October 17, 2023 Category: Drugs & Pharmacology Authors: Changying Xin Kai Duo Xinying Yu Liqun Liu Source Type: research

Evaluation of the effect of granule size of raw tableting materials on critical quality attributes of tablets during the continuous tablet manufacturing process using near-infrared spectroscopy
CONCLUSIONS: The changes in the predicted value profiles of TH and TW using NIRS reflected the changes in the measured values depending on the raw granule size during CTMP.PMID:37847490 | DOI:10.1080/03639045.2023.2271979 (Source: Drug Development and Industrial Pharmacy)
Source: Drug Development and Industrial Pharmacy - October 17, 2023 Category: Drugs & Pharmacology Authors: Makoto Otsuka Tokiro Ogata Yusuke Hattori Tetsuo Sasaki Source Type: research

Evaluation of the in vitro performance of generic and original adapalene gel
Conclusions: The factors mentioned above should be considered when developing and manufacturing generic adapalene gels, and the application of TCS in the evaluation of generic topical drugs was advanced. Additionally, our research revealed some discrepancies from USP < 1724>, which could be valuable information for the revision.PMID:37847563 | DOI:10.1080/03639045.2023.2271966 (Source: Drug Development and Industrial Pharmacy)
Source: Drug Development and Industrial Pharmacy - October 17, 2023 Category: Drugs & Pharmacology Authors: Changying Xin Kai Duo Xinying Yu Liqun Liu Source Type: research

Evaluation of the effect of granule size of raw tableting materials on critical quality attributes of tablets during the continuous tablet manufacturing process using near-infrared spectroscopy
CONCLUSIONS: The changes in the predicted value profiles of TH and TW using NIRS reflected the changes in the measured values depending on the raw granule size during CTMP.PMID:37847490 | DOI:10.1080/03639045.2023.2271979 (Source: Drug Development and Industrial Pharmacy)
Source: Drug Development and Industrial Pharmacy - October 17, 2023 Category: Drugs & Pharmacology Authors: Makoto Otsuka Tokiro Ogata Yusuke Hattori Tetsuo Sasaki Source Type: research

Evaluation of the in vitro performance of generic and original adapalene gel
Conclusions: The factors mentioned above should be considered when developing and manufacturing generic adapalene gels, and the application of TCS in the evaluation of generic topical drugs was advanced. Additionally, our research revealed some discrepancies from USP < 1724>, which could be valuable information for the revision.PMID:37847563 | DOI:10.1080/03639045.2023.2271966 (Source: Drug Development and Industrial Pharmacy)
Source: Drug Development and Industrial Pharmacy - October 17, 2023 Category: Drugs & Pharmacology Authors: Changying Xin Kai Duo Xinying Yu Liqun Liu Source Type: research

Evaluation of the effect of granule size of raw tableting materials on critical quality attributes of tablets during the continuous tablet manufacturing process using near-infrared spectroscopy
CONCLUSIONS: The changes in the predicted value profiles of TH and TW using NIRS reflected the changes in the measured values depending on the raw granule size during CTMP.PMID:37847490 | DOI:10.1080/03639045.2023.2271979 (Source: Drug Development and Industrial Pharmacy)
Source: Drug Development and Industrial Pharmacy - October 17, 2023 Category: Drugs & Pharmacology Authors: Makoto Otsuka Tokiro Ogata Yusuke Hattori Tetsuo Sasaki Source Type: research

Evaluation of the in vitro performance of generic and original adapalene gel
Conclusions: The factors mentioned above should be considered when developing and manufacturing generic adapalene gels, and the application of TCS in the evaluation of generic topical drugs was advanced. Additionally, our research revealed some discrepancies from USP < 1724>, which could be valuable information for the revision.PMID:37847563 | DOI:10.1080/03639045.2023.2271966 (Source: Drug Development and Industrial Pharmacy)
Source: Drug Development and Industrial Pharmacy - October 17, 2023 Category: Drugs & Pharmacology Authors: Changying Xin Kai Duo Xinying Yu Liqun Liu Source Type: research

Evaluation of the effect of granule size of raw tableting materials on critical quality attributes of tablets during the continuous tablet manufacturing process using near-infrared spectroscopy
CONCLUSIONS: The changes in the predicted value profiles of TH and TW using NIRS reflected the changes in the measured values depending on the raw granule size during CTMP.PMID:37847490 | DOI:10.1080/03639045.2023.2271979 (Source: Drug Development and Industrial Pharmacy)
Source: Drug Development and Industrial Pharmacy - October 17, 2023 Category: Drugs & Pharmacology Authors: Makoto Otsuka Tokiro Ogata Yusuke Hattori Tetsuo Sasaki Source Type: research

Evaluation of the in vitro performance of generic and original adapalene gel
Conclusions: The factors mentioned above should be considered when developing and manufacturing generic adapalene gels, and the application of TCS in the evaluation of generic topical drugs was advanced. Additionally, our research revealed some discrepancies from USP < 1724>, which could be valuable information for the revision.PMID:37847563 | DOI:10.1080/03639045.2023.2271966 (Source: Drug Development and Industrial Pharmacy)
Source: Drug Development and Industrial Pharmacy - October 17, 2023 Category: Drugs & Pharmacology Authors: Changying Xin Kai Duo Xinying Yu Liqun Liu Source Type: research

Effective Seed Cake Extract of < em > O. sanctum < /em > inducing the < em > p53 < /em > Dependent Apoptotic Pathway in Oral Cancer Cells
CONCLUSION: The potent therapeutic properties of seed cake extracts have been proven, and they can be used as herbal treatments to prevent oral cancer.PMID:37824711 | DOI:10.1080/03639045.2023.2270063 (Source: Drug Development and Industrial Pharmacy)
Source: Drug Development and Industrial Pharmacy - October 12, 2023 Category: Drugs & Pharmacology Authors: Yash Sharma Rupa Mishra Amritpal Kaur Mausumi Bharadwaj Kumud Bala Source Type: research

The folate-linked chitosan-coated Kaempferol/HSA nano-transporters (FCKH-NTs) as the selective apoptotic inducer in human MCF-7 breast cancer cell line
CONCLUSION: The FCKH-NTs exhibited a selective-cytotoxic impact on human MCF-7 breast cancer cells compared with normal HFF cells, which can be due to the folate receptor-mediated endocytosis mechanism of the nano-transporters. Therefore, the FCKH-NTs have the potential to be used as a selective anti-breast cancer compound.PMID:37814890 | DOI:10.1080/03639045.2023.2268739 (Source: Drug Development and Industrial Pharmacy)
Source: Drug Development and Industrial Pharmacy - October 10, 2023 Category: Drugs & Pharmacology Authors: Mahshad Mollaei Masoud Homayouni Tabrizi Ali Es-Haghi Source Type: research

The folate-linked chitosan-coated Kaempferol/HSA nano-transporters (FCKH-NTs) as the selective apoptotic inducer in human MCF-7 breast cancer cell line
CONCLUSION: The FCKH-NTs exhibited a selective-cytotoxic impact on human MCF-7 breast cancer cells compared with normal HFF cells, which can be due to the folate receptor-mediated endocytosis mechanism of the nano-transporters. Therefore, the FCKH-NTs have the potential to be used as a selective anti-breast cancer compound.PMID:37814890 | DOI:10.1080/03639045.2023.2268739 (Source: Drug Development and Industrial Pharmacy)
Source: Drug Development and Industrial Pharmacy - October 10, 2023 Category: Drugs & Pharmacology Authors: Mahshad Mollaei Masoud Homayouni Tabrizi Ali Es-Haghi Source Type: research