Drug Development and Industrial Pharmacy This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Improving cellular uptake and synergetic anti-tumor effects of magnolol and Brucea javanica oil through self-microemulsion
CONCLUSIONS: The BJO self-microemulsion delivery technique can provide an idea for design of oral delivery vehicles based on BJO.PMID:38466185 | DOI:10.1080/03639045.2024.2329730 (Source: Drug Development and Industrial Pharmacy)
Source: Drug Development and Industrial Pharmacy - March 11, 2024 Category: Drugs & Pharmacology Authors: Huiyun Zhang Yu Zhang Yunfei Hu Shunru Wei Michael Adu-Frimpong Congyong Sun Gang Qi Source Type: research

Formulation and optimisation of Ozenoxacin topical nano-emulgel including a comprehensive methodology to qualify and validate the critical parameters of an in-vitro release test method and ex-vivo permeation test
Conclusion: Based on these results, Ozenoxacin nano-emulgel can be considered an effective alternative and was found to be stable at 40 °C/75% RH and 30 °C/75% RH storage condition for 6 months.PMID:38459688 | DOI:10.1080/03639045.2024.2327466 (Source: Drug Development and Industrial Pharmacy)
Source: Drug Development and Industrial Pharmacy - March 9, 2024 Category: Drugs & Pharmacology Authors: Amarnath Reddy Ramireddy Dilip Kumar Behara Source Type: research

Exposure to Potentially Harmful Excipients in Medications among Neonates at a State Hospital in Malaysia
Conclusion: The exposure of PHE among neonates in this study is high with certain PHEs exceeding the ADI. It highlights the need for certain strategies to be implemented to reduce such exposure in neonates.PMID:38459761 | DOI:10.1080/03639045.2024.2327462 (Source: Drug Development and Industrial Pharmacy)
Source: Drug Development and Industrial Pharmacy - March 9, 2024 Category: Drugs & Pharmacology Authors: Shien Woan Wong Soo Piing Chew Siti Azdiah AbdulAziz Noraida MohamedShah Source Type: research

Computer-aided optimization of carbidopa/levodopa orally disintegrating tablets
Conclusion: The ODTs optimized using RSM and Python demonstrated excellent disintegration performance, leading to a decrease in the time the drug exists in solid form in the oral cavity. This improvement in disintegration time reduced the difficulty of swallowing for patients and enhanced medication compliance, while still ensuring that ODTs prepared by DC had sufficient mechanical strength to meet storage and transportation requirements.PMID:38456721 | DOI:10.1080/03639045.2024.2327475 (Source: Drug Development and Industrial Pharmacy)
Source: Drug Development and Industrial Pharmacy - March 8, 2024 Category: Drugs & Pharmacology Authors: Fucheng Qin Congcong Wan Yuanyuan Zhang Source Type: research

A newly developed UPLC-MS/MS method for simultaneous quantitative analysis of ajuforrestin A, ajuforrestin B, ajugamacrin and 8-O-Acetylharpagide derived from Ajuga Plants in mice blood and the in vivo pharmacokinetics
CONCLUSIONS: In this approach, the corresponding pharmacokinetic parameters were successfully clarified in mouse for the first time, which provided a theoretical basis for the improvement of the standard of Ajuga plants and the safety of clinical medication. Furthermore, this method may provide the UPLC-MS/MS evidence for the differentiation of the main close relative varieties of genus Ajuga according to these plants contain different mixtures of the four marker compounds.PMID:38456836 | DOI:10.1080/03639045.2024.2328731 (Source: Drug Development and Industrial Pharmacy)
Source: Drug Development and Industrial Pharmacy - March 8, 2024 Category: Drugs & Pharmacology Authors: Xiuwei Shen Chen Chen Congcong Wen Shuaishuai Yu Huamin Liu Xiaomin Gao Lianguo Chen Source Type: research

Development, optimization and characterization of cisplatin loaded cubosomes for human lung carcinoma
ConclusionsThe obtained results demonstrated the successful development of cubosomes for sustained delivery of cisplatin.PMID:38451066 | DOI:10.1080/03639045.2024.2326043 (Source: Drug Development and Industrial Pharmacy)
Source: Drug Development and Industrial Pharmacy - March 7, 2024 Category: Drugs & Pharmacology Authors: Hassaan Umar Habibah A Wahab Nadeem Ahmed Nao Akusa Fujimura Muhammad Wahab Amjad Syed Nasir Abbas Bukhari Waqas Ahmad Source Type: research

Combined eutexia and amorphization for simultaneous enhancement of dissolution rate of triamterene and hydrochlorothiazide: preparation of orodispersible tablets
CONCLUSION: The study introduced simple co-processing with traditional excipients for development of ODT of triamterene and hydrochlorothiazide.PMID:38400841 | DOI:10.1080/03639045.2024.2323996 (Source: Drug Development and Industrial Pharmacy)
Source: Drug Development and Industrial Pharmacy - February 24, 2024 Category: Drugs & Pharmacology Authors: Hend A Awad Mohamed I Fetouh Amal A Sultan Gamal M El Maghraby Source Type: research

Combined eutexia and amorphization for simultaneous enhancement of dissolution rate of triamterene and hydrochlorothiazide: Preparation of orodispersible tablets
Conclusion: The study introduced simple co-processing with traditional excipients for development of ODT of triamterene and hydrochlorothiazide.PMID:38400841 | DOI:10.1080/03639045.2024.2323996 (Source: Drug Development and Industrial Pharmacy)
Source: Drug Development and Industrial Pharmacy - February 24, 2024 Category: Drugs & Pharmacology Authors: Hend A Awad Mohamed I Fetouh Amal A Sultan Gamal M ElMaghraby Source Type: research