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Interdigitation of lipids for vesosomal formulation of ergotamine tartrate with caffeine: a futuristic trend of intranasal route
CONCLUSIONS: The stable vesosomes prepared using interdigitation of saturated phospholipids proved to be a viable option for ERG when administered intranasally for better absorption and bioavailability coupled with ease of administration gaining wider patient acceptance.PMID:38158799 | DOI:10.1080/03639045.2023.2301018 (Source: Drug Development and Industrial Pharmacy)
Source: Drug Development and Industrial Pharmacy - December 30, 2023 Category: Drugs & Pharmacology Authors: Preeti Dali Pravin Shende Source Type: research

Interdigitation of lipids for vesosomal formulation of ergotamine tartrate with caffeine: A futuristic trend of intranasal route
Conclusion: The stable vesosomes prepared using interdigitation of saturated phospholipids proved to be a viable option for ergotamine when administered intranasally for better absorption and bioavailability coupled with ease of administration gaining wider patient acceptance.PMID:38158799 | DOI:10.1080/03639045.2023.2301018 (Source: Drug Development and Industrial Pharmacy)
Source: Drug Development and Industrial Pharmacy - December 30, 2023 Category: Drugs & Pharmacology Authors: Preeti Dali Pravin Shende Source Type: research

Development of Oral Formulation of < em > Lepidium < /em > Seeds Significantly Decreases the High Blood Glucose Levels in Diabetic Rats; In Vitro Formulation and In Vivo Antidiabetic Performance
CONCLUSION: GC tablets could be a promising alternative formulation to control the high blood glucose level in diabetic rats rather than chemically derivatized drugs.PMID:38156891 | DOI:10.1080/03639045.2023.2300649 (Source: Drug Development and Industrial Pharmacy)
Source: Drug Development and Industrial Pharmacy - December 29, 2023 Category: Drugs & Pharmacology Authors: Basmah N Aldosari Ahmed A H Abdellatif Alanood Sunhat Almurshedi Iman Mohammed Alfagih Bushra Tawfeeq AlQuadeib Asmaa Youssef A Abbas Yasser A Hassan Ahmed Abdelfattah Hesham M Tawfeek Source Type: research

Intranasal administration of innovative triamcinolone acetonide encapsulated cubosomal < em > in situ < /em > gel: formulation and characterization
Conclusion: The utilization of an intranasal cubosomal in situ gel encapsulated with TCA was anticipated to lower intracranial pressure and improve patient adherence by offering effective relief for individuals suffering from Brain edema. This efficacy is attributed to its rapid onset of action and its safe and well-tolerated dosage form.PMID:38148515 | DOI:10.1080/03639045.2023.2297275 (Source: Drug Development and Industrial Pharmacy)
Source: Drug Development and Industrial Pharmacy - December 27, 2023 Category: Drugs & Pharmacology Authors: Ruturaj Patil Archana S Patil Krutuja Chougule Yadishma Gaude Rajashree S Masareddy Source Type: research

Development of a novel direct compressible co-processed excipient and its application for formulation of Mirtazapine orally disintegrating tablets
CONCLUSION: Therefore, the developed co-processed excipients show great potential in enhancing the functionalities of ODTs, offering a promising solution to improve the overall performance and usability of ODTs in various therapeutic applications.PMID:38149637 | DOI:10.1080/03639045.2023.2294095 (Source: Drug Development and Industrial Pharmacy)
Source: Drug Development and Industrial Pharmacy - December 27, 2023 Category: Drugs & Pharmacology Authors: Ying Hui Loke Yik-Ling Chew Ashok Kumar Janakiraman Siew-Keah Lee A B M Helal Uddin Choon Fu Goh Phei Er Kee Hui Suan Ng Long Chiau Ming Kai Bin Liew Source Type: research

Intranasal administration of innovative triamcinolone acetonide encapsulated cubosomal < em > in situ < /em > gel: formulation and characterization
Conclusion: The utilization of an intranasal cubosomal in situ gel encapsulated with TCA was anticipated to lower intracranial pressure and improve patient adherence by offering effective relief for individuals suffering from Brain edema. This efficacy is attributed to its rapid onset of action and its safe and well-tolerated dosage form.PMID:38148515 | DOI:10.1080/03639045.2023.2297275 (Source: Drug Development and Industrial Pharmacy)
Source: Drug Development and Industrial Pharmacy - December 27, 2023 Category: Drugs & Pharmacology Authors: Ruturaj Patil Archana S Patil Krutuja Chougule Yadishma Gaude Rajashree S Masareddy Source Type: research

Development of a novel direct compressible co-processed excipient and its application for formulation of Mirtazapine orally disintegrating tablets
CONCLUSION: Therefore, the developed co-processed excipients show great potential in enhancing the functionalities of ODTs, offering a promising solution to improve the overall performance and usability of ODTs in various therapeutic applications.PMID:38149637 | DOI:10.1080/03639045.2023.2294095 (Source: Drug Development and Industrial Pharmacy)
Source: Drug Development and Industrial Pharmacy - December 27, 2023 Category: Drugs & Pharmacology Authors: Ying Hui Loke Yik-Ling Chew Ashok Kumar Janakiraman Siew-Keah Lee A B M Helal Uddin Choon Fu Goh Phei Er Kee Hui Suan Ng Long Chiau Ming Kai Bin Liew Source Type: research

Intranasal administration of innovative triamcinolone acetonide encapsulated cubosomal < em > in situ < /em > gel: formulation and characterization
Conclusion: The utilization of an intranasal cubosomal in situ gel encapsulated with TCA was anticipated to lower intracranial pressure and improve patient adherence by offering effective relief for individuals suffering from Brain edema. This efficacy is attributed to its rapid onset of action and its safe and well-tolerated dosage form.PMID:38148515 | DOI:10.1080/03639045.2023.2297275 (Source: Drug Development and Industrial Pharmacy)
Source: Drug Development and Industrial Pharmacy - December 27, 2023 Category: Drugs & Pharmacology Authors: Ruturaj Patil Archana S Patil Krutuja Chougule Yadishma Gaude Rajashree S Masareddy Source Type: research

Development of a novel direct compressible co-processed excipient and its application for formulation of Mirtazapine orally disintegrating tablets
CONCLUSION: Therefore, the developed co-processed excipients show great potential in enhancing the functionalities of ODTs, offering a promising solution to improve the overall performance and usability of ODTs in various therapeutic applications.PMID:38149637 | DOI:10.1080/03639045.2023.2294095 (Source: Drug Development and Industrial Pharmacy)
Source: Drug Development and Industrial Pharmacy - December 27, 2023 Category: Drugs & Pharmacology Authors: Ying Hui Loke Yik-Ling Chew Ashok Kumar Janakiraman Siew-Keah Lee A B M Helal Uddin Choon Fu Goh Phei Er Kee Hui Suan Ng Long Chiau Ming Kai Bin Liew Source Type: research

Intranasal administration of innovative triamcinolone acetonide encapsulated cubosomal < em > in situ < /em > gel: formulation and characterization
Conclusion: The utilization of an intranasal cubosomal in situ gel encapsulated with TCA was anticipated to lower intracranial pressure and improve patient adherence by offering effective relief for individuals suffering from Brain edema. This efficacy is attributed to its rapid onset of action and its safe and well-tolerated dosage form.PMID:38148515 | DOI:10.1080/03639045.2023.2297275 (Source: Drug Development and Industrial Pharmacy)
Source: Drug Development and Industrial Pharmacy - December 27, 2023 Category: Drugs & Pharmacology Authors: Ruturaj Patil Archana S Patil Krutuja Chougule Yadishma Gaude Rajashree S Masareddy Source Type: research

Development of a novel direct compressible co-processed excipient and its application for formulation of Mirtazapine orally disintegrating tablets
CONCLUSION: Therefore, the developed co-processed excipients show great potential in enhancing the functionalities of ODTs, offering a promising solution to improve the overall performance and usability of ODTs in various therapeutic applications.PMID:38149637 | DOI:10.1080/03639045.2023.2294095 (Source: Drug Development and Industrial Pharmacy)
Source: Drug Development and Industrial Pharmacy - December 27, 2023 Category: Drugs & Pharmacology Authors: Ying Hui Loke Yik-Ling Chew Ashok Kumar Janakiraman Siew-Keah Lee A B M Helal Uddin Choon Fu Goh Phei Er Kee Hui Suan Ng Long Chiau Ming Kai Bin Liew Source Type: research

Intranasal administration of innovative triamcinolone acetonide encapsulated cubosomal < em > in situ < /em > gel: formulation and characterization
Conclusion: The utilization of an intranasal cubosomal in situ gel encapsulated with TCA was anticipated to lower intracranial pressure and improve patient adherence by offering effective relief for individuals suffering from Brain edema. This efficacy is attributed to its rapid onset of action and its safe and well-tolerated dosage form.PMID:38148515 | DOI:10.1080/03639045.2023.2297275 (Source: Drug Development and Industrial Pharmacy)
Source: Drug Development and Industrial Pharmacy - December 27, 2023 Category: Drugs & Pharmacology Authors: Ruturaj Patil Archana S Patil Krutuja Chougule Yadishma Gaude Rajashree S Masareddy Source Type: research

Development of a novel direct compressible co-processed excipient and its application for formulation of Mirtazapine orally disintegrating tablets
CONCLUSION: Therefore, the developed co-processed excipients show great potential in enhancing the functionalities of ODTs, offering a promising solution to improve the overall performance and usability of ODTs in various therapeutic applications.PMID:38149637 | DOI:10.1080/03639045.2023.2294095 (Source: Drug Development and Industrial Pharmacy)
Source: Drug Development and Industrial Pharmacy - December 27, 2023 Category: Drugs & Pharmacology Authors: Ying Hui Loke Yik-Ling Chew Ashok Kumar Janakiraman Siew-Keah Lee A B M Helal Uddin Choon Fu Goh Phei Er Kee Hui Suan Ng Long Chiau Ming Kai Bin Liew Source Type: research

Enhancing oral bioavailability of Ca-DTPA by Self Double Emulsifying Drug Delivery System (SDEDDS)
CONCLUSION: The present studies have clearly demonstrated that SDEDDS could readily form w/o/w double emulsions in vivo with enhanced in vitro and in vivo oral bioavailability. Therefore considerable augmentation in the rate and extent of oral drug absorption ratified the better performance of the SDEDDS in enhancing the bioavailability of Ca-DTPA.PMID:38145420 | DOI:10.1080/03639045.2023.2298881 (Source: Drug Development and Industrial Pharmacy)
Source: Drug Development and Industrial Pharmacy - December 25, 2023 Category: Drugs & Pharmacology Authors: Vaishali Agrawal Anjali Priyadarshani Dharam Pal Pathak Nidhi Sandal Source Type: research