Fabrication, Properties, and Stability of Oregano Essential Oil and Sodium Alginate-Based Wound-Healing Hydrogels
Dose Response. 2023 Oct 9;21(4):15593258231204186. doi: 10.1177/15593258231204186. eCollection 2023 Oct-Dec.ABSTRACTThe wound dressings fabricated by polymers and oregano essential oil (OEO) can be very effective as a hydrogel. The current study has been focused on fabricating the hydrogel membranes of oregano oil encapsulated as an antibacterial agent into sodium alginate (SA) solution by solvent casting method and then evaluated the antibacterial, antioxidant activity, and physicochemical performance of SA/OEO-based polymeric membranes. The polymeric interactions, surface morphology, water absorption capability, thermal ...
Source: Dose Response - October 12, 2023 Category: Drugs & Pharmacology Authors: Dure Najaf Iqbal Asia Ashraf Arif Nazir Samar Z Alshawwa Munawar Iqbal Naveed Ahmad Source Type: research
Fabrication, Properties, and Stability of Oregano Essential Oil and Sodium Alginate-Based Wound-Healing Hydrogels
Dose Response. 2023 Oct 9;21(4):15593258231204186. doi: 10.1177/15593258231204186. eCollection 2023 Oct-Dec.ABSTRACTThe wound dressings fabricated by polymers and oregano essential oil (OEO) can be very effective as a hydrogel. The current study has been focused on fabricating the hydrogel membranes of oregano oil encapsulated as an antibacterial agent into sodium alginate (SA) solution by solvent casting method and then evaluated the antibacterial, antioxidant activity, and physicochemical performance of SA/OEO-based polymeric membranes. The polymeric interactions, surface morphology, water absorption capability, thermal ...
Source: Dose Response - October 12, 2023 Category: Drugs & Pharmacology Authors: Dure Najaf Iqbal Asia Ashraf Arif Nazir Samar Z Alshawwa Munawar Iqbal Naveed Ahmad Source Type: research
Dose Dependent Effect of Sulfamethoxazole on Inhibiting K < sub > ATP < /sub > Channel of Mouse Pancreatic β Cell
In this study, whole-cell patch clamp recording was utilized to measure the effect of SMX on KATP channel activity on pancreatic β cells. Also, the static incubation assay with mice islets was assessed to measure the insulin secretion capacity of SMX. SMX was shown to inhibit the KATP channel in pancreatic β cell membrane and induce insulin secretion in relatively high concentration. The half maximal inhibitory concentration (IC50) for KATP channel activity of SMX was .46 ± .08 mM. It was also shown that a near IC50 concentration of SMX (.5 mM) was able to nearly fully block the KATP channel when simultaneously applied ...
Source: Dose Response - October 2, 2023 Category: Drugs & Pharmacology Authors: Hiroshi Ogata Shigeki Kitamura Makoto Fujiwara Masaru Shimizu Chengbo Tan Songji Zhao Yuko Maejima Kenju Shimomura Source Type: research
Dose Dependent Effect of Sulfamethoxazole on Inhibiting K < sub > ATP < /sub > Channel of Mouse Pancreatic β Cell
In this study, whole-cell patch clamp recording was utilized to measure the effect of SMX on KATP channel activity on pancreatic β cells. Also, the static incubation assay with mice islets was assessed to measure the insulin secretion capacity of SMX. SMX was shown to inhibit the KATP channel in pancreatic β cell membrane and induce insulin secretion in relatively high concentration. The half maximal inhibitory concentration (IC50) for KATP channel activity of SMX was .46 ± .08 mM. It was also shown that a near IC50 concentration of SMX (.5 mM) was able to nearly fully block the KATP channel when simultaneously applied ...
Source: Dose Response - October 2, 2023 Category: Drugs & Pharmacology Authors: Hiroshi Ogata Shigeki Kitamura Makoto Fujiwara Masaru Shimizu Chengbo Tan Songji Zhao Yuko Maejima Kenju Shimomura Source Type: research
Dose Dependent Effect of Sulfamethoxazole on Inhibiting K < sub > ATP < /sub > Channel of Mouse Pancreatic β Cell
In this study, whole-cell patch clamp recording was utilized to measure the effect of SMX on KATP channel activity on pancreatic β cells. Also, the static incubation assay with mice islets was assessed to measure the insulin secretion capacity of SMX. SMX was shown to inhibit the KATP channel in pancreatic β cell membrane and induce insulin secretion in relatively high concentration. The half maximal inhibitory concentration (IC50) for KATP channel activity of SMX was .46 ± .08 mM. It was also shown that a near IC50 concentration of SMX (.5 mM) was able to nearly fully block the KATP channel when simultaneously applied ...
Source: Dose Response - October 2, 2023 Category: Drugs & Pharmacology Authors: Hiroshi Ogata Shigeki Kitamura Makoto Fujiwara Masaru Shimizu Chengbo Tan Songji Zhao Yuko Maejima Kenju Shimomura Source Type: research
Dose Dependent Effect of Sulfamethoxazole on Inhibiting K < sub > ATP < /sub > Channel of Mouse Pancreatic β Cell
In this study, whole-cell patch clamp recording was utilized to measure the effect of SMX on KATP channel activity on pancreatic β cells. Also, the static incubation assay with mice islets was assessed to measure the insulin secretion capacity of SMX. SMX was shown to inhibit the KATP channel in pancreatic β cell membrane and induce insulin secretion in relatively high concentration. The half maximal inhibitory concentration (IC50) for KATP channel activity of SMX was .46 ± .08 mM. It was also shown that a near IC50 concentration of SMX (.5 mM) was able to nearly fully block the KATP channel when simultaneously applied ...
Source: Dose Response - October 2, 2023 Category: Drugs & Pharmacology Authors: Hiroshi Ogata Shigeki Kitamura Makoto Fujiwara Masaru Shimizu Chengbo Tan Songji Zhao Yuko Maejima Kenju Shimomura Source Type: research
Dose Dependent Effect of Sulfamethoxazole on Inhibiting K < sub > ATP < /sub > Channel of Mouse Pancreatic β Cell
In this study, whole-cell patch clamp recording was utilized to measure the effect of SMX on KATP channel activity on pancreatic β cells. Also, the static incubation assay with mice islets was assessed to measure the insulin secretion capacity of SMX. SMX was shown to inhibit the KATP channel in pancreatic β cell membrane and induce insulin secretion in relatively high concentration. The half maximal inhibitory concentration (IC50) for KATP channel activity of SMX was .46 ± .08 mM. It was also shown that a near IC50 concentration of SMX (.5 mM) was able to nearly fully block the KATP channel when simultaneously applied ...
Source: Dose Response - October 2, 2023 Category: Drugs & Pharmacology Authors: Hiroshi Ogata Shigeki Kitamura Makoto Fujiwara Masaru Shimizu Chengbo Tan Songji Zhao Yuko Maejima Kenju Shimomura Source Type: research
Dose Dependent Effect of Sulfamethoxazole on Inhibiting K < sub > ATP < /sub > Channel of Mouse Pancreatic β Cell
In this study, whole-cell patch clamp recording was utilized to measure the effect of SMX on KATP channel activity on pancreatic β cells. Also, the static incubation assay with mice islets was assessed to measure the insulin secretion capacity of SMX. SMX was shown to inhibit the KATP channel in pancreatic β cell membrane and induce insulin secretion in relatively high concentration. The half maximal inhibitory concentration (IC50) for KATP channel activity of SMX was .46 ± .08 mM. It was also shown that a near IC50 concentration of SMX (.5 mM) was able to nearly fully block the KATP channel when simultaneously applied ...
Source: Dose Response - October 2, 2023 Category: Drugs & Pharmacology Authors: Hiroshi Ogata Shigeki Kitamura Makoto Fujiwara Masaru Shimizu Chengbo Tan Songji Zhao Yuko Maejima Kenju Shimomura Source Type: research
Dose Dependent Effect of Sulfamethoxazole on Inhibiting K < sub > ATP < /sub > Channel of Mouse Pancreatic β Cell
In this study, whole-cell patch clamp recording was utilized to measure the effect of SMX on KATP channel activity on pancreatic β cells. Also, the static incubation assay with mice islets was assessed to measure the insulin secretion capacity of SMX. SMX was shown to inhibit the KATP channel in pancreatic β cell membrane and induce insulin secretion in relatively high concentration. The half maximal inhibitory concentration (IC50) for KATP channel activity of SMX was .46 ± .08 mM. It was also shown that a near IC50 concentration of SMX (.5 mM) was able to nearly fully block the KATP channel when simultaneously applied ...
Source: Dose Response - October 2, 2023 Category: Drugs & Pharmacology Authors: Hiroshi Ogata Shigeki Kitamura Makoto Fujiwara Masaru Shimizu Chengbo Tan Songji Zhao Yuko Maejima Kenju Shimomura Source Type: research
Dose Dependent Effect of Sulfamethoxazole on Inhibiting K < sub > ATP < /sub > Channel of Mouse Pancreatic β Cell
In this study, whole-cell patch clamp recording was utilized to measure the effect of SMX on KATP channel activity on pancreatic β cells. Also, the static incubation assay with mice islets was assessed to measure the insulin secretion capacity of SMX. SMX was shown to inhibit the KATP channel in pancreatic β cell membrane and induce insulin secretion in relatively high concentration. The half maximal inhibitory concentration (IC50) for KATP channel activity of SMX was .46 ± .08 mM. It was also shown that a near IC50 concentration of SMX (.5 mM) was able to nearly fully block the KATP channel when simultaneously applied ...
Source: Dose Response - October 2, 2023 Category: Drugs & Pharmacology Authors: Hiroshi Ogata Shigeki Kitamura Makoto Fujiwara Masaru Shimizu Chengbo Tan Songji Zhao Yuko Maejima Kenju Shimomura Source Type: research
Toxic Potential of Crude Extract From Cassava Cortex Containing Scopoletin and Cyanide on Wistar Rats and Broilers
Dose Response. 2023 Sep 22;21(3):15593258231203587. doi: 10.1177/15593258231203587. eCollection 2023 Jul-Sep.ABSTRACTThe present work aimed to evaluate acute and sub-acute toxicity of cortex cassava crude extract containing scopoletin and cyanide. The limit test method of OECD at 2000 mg/kg was used to determine the LD50 of the crude extract in female Wistar rats, and the sub-acute toxicity was conducted in broilers by incorporating their feed with the cortex powder at 2 mg, 4 mg and 8 mg of powder per 100 g of standard food, corresponding to MIC, 2MIC and 4MIC: those concentrations, respectively, corresponded to .07 μg, ...
Source: Dose Response - September 25, 2023 Category: Drugs & Pharmacology Authors: Youchahou Ndam Njankouo Maximilienne Ascension Nyegue Ibrahim Njingou Paul Fewou Moundipa Pauline Mounjouenpou Source Type: research
Toxic Potential of Crude Extract From Cassava Cortex Containing Scopoletin and Cyanide on Wistar Rats and Broilers
Dose Response. 2023 Sep 22;21(3):15593258231203587. doi: 10.1177/15593258231203587. eCollection 2023 Jul-Sep.ABSTRACTThe present work aimed to evaluate acute and sub-acute toxicity of cortex cassava crude extract containing scopoletin and cyanide. The limit test method of OECD at 2000 mg/kg was used to determine the LD50 of the crude extract in female Wistar rats, and the sub-acute toxicity was conducted in broilers by incorporating their feed with the cortex powder at 2 mg, 4 mg and 8 mg of powder per 100 g of standard food, corresponding to MIC, 2MIC and 4MIC: those concentrations, respectively, corresponded to .07 μg, ...
Source: Dose Response - September 25, 2023 Category: Drugs & Pharmacology Authors: Youchahou Ndam Njankouo Maximilienne Ascension Nyegue Ibrahim Njingou Paul Fewou Moundipa Pauline Mounjouenpou Source Type: research
Toxic Potential of Crude Extract From Cassava Cortex Containing Scopoletin and Cyanide on Wistar Rats and Broilers
Dose Response. 2023 Sep 22;21(3):15593258231203587. doi: 10.1177/15593258231203587. eCollection 2023 Jul-Sep.ABSTRACTThe present work aimed to evaluate acute and sub-acute toxicity of cortex cassava crude extract containing scopoletin and cyanide. The limit test method of OECD at 2000 mg/kg was used to determine the LD50 of the crude extract in female Wistar rats, and the sub-acute toxicity was conducted in broilers by incorporating their feed with the cortex powder at 2 mg, 4 mg and 8 mg of powder per 100 g of standard food, corresponding to MIC, 2MIC and 4MIC: those concentrations, respectively, corresponded to .07 μg, ...
Source: Dose Response - September 25, 2023 Category: Drugs & Pharmacology Authors: Youchahou Ndam Njankouo Maximilienne Ascension Nyegue Ibrahim Njingou Paul Fewou Moundipa Pauline Mounjouenpou Source Type: research
Toxic Potential of Crude Extract From Cassava Cortex Containing Scopoletin and Cyanide on Wistar Rats and Broilers
Dose Response. 2023 Sep 22;21(3):15593258231203587. doi: 10.1177/15593258231203587. eCollection 2023 Jul-Sep.ABSTRACTThe present work aimed to evaluate acute and sub-acute toxicity of cortex cassava crude extract containing scopoletin and cyanide. The limit test method of OECD at 2000 mg/kg was used to determine the LD50 of the crude extract in female Wistar rats, and the sub-acute toxicity was conducted in broilers by incorporating their feed with the cortex powder at 2 mg, 4 mg and 8 mg of powder per 100 g of standard food, corresponding to MIC, 2MIC and 4MIC: those concentrations, respectively, corresponded to .07 μg, ...
Source: Dose Response - September 25, 2023 Category: Drugs & Pharmacology Authors: Youchahou Ndam Njankouo Maximilienne Ascension Nyegue Ibrahim Njingou Paul Fewou Moundipa Pauline Mounjouenpou Source Type: research
Toxic Potential of Crude Extract From Cassava Cortex Containing Scopoletin and Cyanide on Wistar Rats and Broilers
Dose Response. 2023 Sep 22;21(3):15593258231203587. doi: 10.1177/15593258231203587. eCollection 2023 Jul-Sep.ABSTRACTThe present work aimed to evaluate acute and sub-acute toxicity of cortex cassava crude extract containing scopoletin and cyanide. The limit test method of OECD at 2000 mg/kg was used to determine the LD50 of the crude extract in female Wistar rats, and the sub-acute toxicity was conducted in broilers by incorporating their feed with the cortex powder at 2 mg, 4 mg and 8 mg of powder per 100 g of standard food, corresponding to MIC, 2MIC and 4MIC: those concentrations, respectively, corresponded to .07 μg, ...
Source: Dose Response - September 25, 2023 Category: Drugs & Pharmacology Authors: Youchahou Ndam Njankouo Maximilienne Ascension Nyegue Ibrahim Njingou Paul Fewou Moundipa Pauline Mounjouenpou Source Type: research
