Curcumin's Dose-Dependent Attenuation of Gastric Cancer Cell Progression Via the PI3K Pathway Blockade
Conclusion: These findings propose that curcumin may exercise its anti-cancer effects on gastric cancer cells, partly by suppressing the PI3K signaling pathway. This study's outcomes support curcumin's potential as a therapeutic agent for gastric cancer and encourage further exploration of its underlying molecular mechanisms and in vivo effectiveness.PMID:37933268 | PMC:PMC10625731 | DOI:10.1177/15593258231203585 (Source: Dose Response)
Source: Dose Response - November 7, 2023 Category: Drugs & Pharmacology Authors: Gen Xi Qingtao Dong Bo Yang Desheng Jiao Shahanavaj Khan Source Type: research
Air Pollution and Cardiac Diseases: A Review of Experimental Studies
Dose Response. 2023 Nov 4;21(4):15593258231212793. doi: 10.1177/15593258231212793. eCollection 2023 Oct-Dec.ABSTRACTAir pollution is associated with around 6.5 million premature deaths annually, which are directly related to cardiovascular diseases, and the most dangerous atmospheric pollutants to health are as follows: NO2, SO2, CO, and PM. The mechanisms underlying the observed effects have not yet been clearly defined. This work aims to conduct a narrative review of experimental studies to provide a more comprehensive and multiperspective assessment of how the effect of atmospheric pollutants on cardiac activity can res...
Source: Dose Response - November 7, 2023 Category: Drugs & Pharmacology Authors: Laura C Palacio Diana C Pachajoa Carlos A Echeverri-Londo ño Javier Saiz Catalina Tob ón Source Type: research
Curcumin's Dose-Dependent Attenuation of Gastric Cancer Cell Progression Via the PI3K Pathway Blockade
Conclusion: These findings propose that curcumin may exercise its anti-cancer effects on gastric cancer cells, partly by suppressing the PI3K signaling pathway. This study's outcomes support curcumin's potential as a therapeutic agent for gastric cancer and encourage further exploration of its underlying molecular mechanisms and in vivo effectiveness.PMID:37933268 | PMC:PMC10625731 | DOI:10.1177/15593258231203585 (Source: Dose Response)
Source: Dose Response - November 7, 2023 Category: Drugs & Pharmacology Authors: Gen Xi Qingtao Dong Bo Yang Desheng Jiao Shahanavaj Khan Source Type: research
Air Pollution and Cardiac Diseases: A Review of Experimental Studies
Dose Response. 2023 Nov 4;21(4):15593258231212793. doi: 10.1177/15593258231212793. eCollection 2023 Oct-Dec.ABSTRACTAir pollution is associated with around 6.5 million premature deaths annually, which are directly related to cardiovascular diseases, and the most dangerous atmospheric pollutants to health are as follows: NO2, SO2, CO, and PM. The mechanisms underlying the observed effects have not yet been clearly defined. This work aims to conduct a narrative review of experimental studies to provide a more comprehensive and multiperspective assessment of how the effect of atmospheric pollutants on cardiac activity can res...
Source: Dose Response - November 7, 2023 Category: Drugs & Pharmacology Authors: Laura C Palacio Diana C Pachajoa Carlos A Echeverri-Londo ño Javier Saiz Catalina Tob ón Source Type: research
Curcumin's Dose-Dependent Attenuation of Gastric Cancer Cell Progression Via the PI3K Pathway Blockade
Conclusion: These findings propose that curcumin may exercise its anti-cancer effects on gastric cancer cells, partly by suppressing the PI3K signaling pathway. This study's outcomes support curcumin's potential as a therapeutic agent for gastric cancer and encourage further exploration of its underlying molecular mechanisms and in vivo effectiveness.PMID:37933268 | PMC:PMC10625731 | DOI:10.1177/15593258231203585 (Source: Dose Response)
Source: Dose Response - November 7, 2023 Category: Drugs & Pharmacology Authors: Gen Xi Qingtao Dong Bo Yang Desheng Jiao Shahanavaj Khan Source Type: research
Air Pollution and Cardiac Diseases: A Review of Experimental Studies
Dose Response. 2023 Nov 4;21(4):15593258231212793. doi: 10.1177/15593258231212793. eCollection 2023 Oct-Dec.ABSTRACTAir pollution is associated with around 6.5 million premature deaths annually, which are directly related to cardiovascular diseases, and the most dangerous atmospheric pollutants to health are as follows: NO2, SO2, CO, and PM. The mechanisms underlying the observed effects have not yet been clearly defined. This work aims to conduct a narrative review of experimental studies to provide a more comprehensive and multiperspective assessment of how the effect of atmospheric pollutants on cardiac activity can res...
Source: Dose Response - November 7, 2023 Category: Drugs & Pharmacology Authors: Laura C Palacio Diana C Pachajoa Carlos A Echeverri-Londo ño Javier Saiz Catalina Tob ón Source Type: research
Assessing the Risk of Secondary Cancer Induction in Radiosensitive Organs During Trigeminal Neuralgia Treatment With Gamma Knife Radiosurgery: Impact of Extracranial Dose
CONCLUSION: The results of this study and its comparison with standard values demonstrate that on average, mean doses to mentioned organs were smaller than their tolerance doses, and there is no limitation to treating patients suffering from TN by GK.PMID:37900619 | PMC:PMC10605703 | DOI:10.1177/15593258231210432 (Source: Dose Response)
Source: Dose Response - October 30, 2023 Category: Drugs & Pharmacology Authors: Ghazale Geraily Ali Ameri Atefeh Mahmoudi Mohadese Moafee Javad Teymouri Source Type: research
In Vitro Antioxidant and Inhibitory Study of < em > Picrorhiza kurroa < /em > (Kutki), < em > Syzygium aromaticum < /em > (Loung), < em > Lawsonia inermis < /em > (Henna), < em > Rheum emodi < /em > (Revand Chini), < em > Curcuma longa < /em > (Haldi) Against Lipid Per-Oxidation in Mice Brain and Liver
This study was done to evaluate the antioxidant and protective properties of P kurroa, S aromaticum, L inermis, R emodi, and C longa against lipid peroxidation induced by different pro-oxidants. The aqueous extracts of these medicinal plants showed inhibition against thiobarbituric acid reactive species (TBARS) induced by different pro-oxidants (10 mM FeSO4 and 5 mM sodium nitroprusside) in the brain and liver of mice. Moreover, the free radical scavenging activities of the extracts were evaluated by the scavenging of the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical. L inermis, S aromaticum, and R emodi showed higher inhib...
Source: Dose Response - October 30, 2023 Category: Drugs & Pharmacology Authors: Farooq Hassan Asmat Ullah Khan Syed Zahoor Ul Hassan Zaidi Madiha Khan Niazi Muhammad Amjed Ismail Source Type: research
Assessing the Risk of Secondary Cancer Induction in Radiosensitive Organs During Trigeminal Neuralgia Treatment With Gamma Knife Radiosurgery: Impact of Extracranial Dose
CONCLUSION: The results of this study and its comparison with standard values demonstrate that on average, mean doses to mentioned organs were smaller than their tolerance doses, and there is no limitation to treating patients suffering from TN by GK.PMID:37900619 | PMC:PMC10605703 | DOI:10.1177/15593258231210432 (Source: Dose Response)
Source: Dose Response - October 30, 2023 Category: Drugs & Pharmacology Authors: Ghazale Geraily Ali Ameri Atefeh Mahmoudi Mohadese Moafee Javad Teymouri Source Type: research
In Vitro Antioxidant and Inhibitory Study of < em > Picrorhiza kurroa < /em > (Kutki), < em > Syzygium aromaticum < /em > (Loung), < em > Lawsonia inermis < /em > (Henna), < em > Rheum emodi < /em > (Revand Chini), < em > Curcuma longa < /em > (Haldi) Against Lipid Per-Oxidation in Mice Brain and Liver
This study was done to evaluate the antioxidant and protective properties of P kurroa, S aromaticum, L inermis, R emodi, and C longa against lipid peroxidation induced by different pro-oxidants. The aqueous extracts of these medicinal plants showed inhibition against thiobarbituric acid reactive species (TBARS) induced by different pro-oxidants (10 mM FeSO4 and 5 mM sodium nitroprusside) in the brain and liver of mice. Moreover, the free radical scavenging activities of the extracts were evaluated by the scavenging of the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical. L inermis, S aromaticum, and R emodi showed higher inhib...
Source: Dose Response - October 30, 2023 Category: Drugs & Pharmacology Authors: Farooq Hassan Asmat Ullah Khan Syed Zahoor Ul Hassan Zaidi Madiha Khan Niazi Muhammad Amjed Ismail Source Type: research
Assessing the Risk of Secondary Cancer Induction in Radiosensitive Organs During Trigeminal Neuralgia Treatment With Gamma Knife Radiosurgery: Impact of Extracranial Dose
CONCLUSION: The results of this study and its comparison with standard values demonstrate that on average, mean doses to mentioned organs were smaller than their tolerance doses, and there is no limitation to treating patients suffering from TN by GK.PMID:37900619 | PMC:PMC10605703 | DOI:10.1177/15593258231210432 (Source: Dose Response)
Source: Dose Response - October 30, 2023 Category: Drugs & Pharmacology Authors: Ghazale Geraily Ali Ameri Atefeh Mahmoudi Mohadese Moafee Javad Teymouri Source Type: research
In Vitro Antioxidant and Inhibitory Study of < em > Picrorhiza kurroa < /em > (Kutki), < em > Syzygium aromaticum < /em > (Loung), < em > Lawsonia inermis < /em > (Henna), < em > Rheum emodi < /em > (Revand Chini), < em > Curcuma longa < /em > (Haldi) Against Lipid Per-Oxidation in Mice Brain and Liver
This study was done to evaluate the antioxidant and protective properties of P kurroa, S aromaticum, L inermis, R emodi, and C longa against lipid peroxidation induced by different pro-oxidants. The aqueous extracts of these medicinal plants showed inhibition against thiobarbituric acid reactive species (TBARS) induced by different pro-oxidants (10 mM FeSO4 and 5 mM sodium nitroprusside) in the brain and liver of mice. Moreover, the free radical scavenging activities of the extracts were evaluated by the scavenging of the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical. L inermis, S aromaticum, and R emodi showed higher inhib...
Source: Dose Response - October 30, 2023 Category: Drugs & Pharmacology Authors: Farooq Hassan Asmat Ullah Khan Syed Zahoor Ul Hassan Zaidi Madiha Khan Niazi Muhammad Amjed Ismail Source Type: research
Assessing the Risk of Secondary Cancer Induction in Radiosensitive Organs During Trigeminal Neuralgia Treatment With Gamma Knife Radiosurgery: Impact of Extracranial Dose
CONCLUSION: The results of this study and its comparison with standard values demonstrate that on average, mean doses to mentioned organs were smaller than their tolerance doses, and there is no limitation to treating patients suffering from TN by GK.PMID:37900619 | PMC:PMC10605703 | DOI:10.1177/15593258231210432 (Source: Dose Response)
Source: Dose Response - October 30, 2023 Category: Drugs & Pharmacology Authors: Ghazale Geraily Ali Ameri Atefeh Mahmoudi Mohadese Moafee Javad Teymouri Source Type: research
In Vitro Antioxidant and Inhibitory Study of < em > Picrorhiza kurroa < /em > (Kutki), < em > Syzygium aromaticum < /em > (Loung), < em > Lawsonia inermis < /em > (Henna), < em > Rheum emodi < /em > (Revand Chini), < em > Curcuma longa < /em > (Haldi) Against Lipid Per-Oxidation in Mice Brain and Liver
This study was done to evaluate the antioxidant and protective properties of P kurroa, S aromaticum, L inermis, R emodi, and C longa against lipid peroxidation induced by different pro-oxidants. The aqueous extracts of these medicinal plants showed inhibition against thiobarbituric acid reactive species (TBARS) induced by different pro-oxidants (10 mM FeSO4 and 5 mM sodium nitroprusside) in the brain and liver of mice. Moreover, the free radical scavenging activities of the extracts were evaluated by the scavenging of the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical. L inermis, S aromaticum, and R emodi showed higher inhib...
Source: Dose Response - October 30, 2023 Category: Drugs & Pharmacology Authors: Farooq Hassan Asmat Ullah Khan Syed Zahoor Ul Hassan Zaidi Madiha Khan Niazi Muhammad Amjed Ismail Source Type: research
Assessing the Risk of Secondary Cancer Induction in Radiosensitive Organs During Trigeminal Neuralgia Treatment With Gamma Knife Radiosurgery: Impact of Extracranial Dose
CONCLUSION: The results of this study and its comparison with standard values demonstrate that on average, mean doses to mentioned organs were smaller than their tolerance doses, and there is no limitation to treating patients suffering from TN by GK.PMID:37900619 | PMC:PMC10605703 | DOI:10.1177/15593258231210432 (Source: Dose Response)
Source: Dose Response - October 30, 2023 Category: Drugs & Pharmacology Authors: Ghazale Geraily Ali Ameri Atefeh Mahmoudi Mohadese Moafee Javad Teymouri Source Type: research
