Quantities of CD3+, CD8+ and CD56+ lymphocytes decline in breast cancer recurrences while CD4+ remain similar
Much is known about tumor infiltrating lymphocytes (Tils) in primary breast cancer, as this has been the focus of much research in recent years, but regarding recurrent breast cancer, only few studies have bee... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - January 10, 2023 Category: Pathology Authors: Minna Mutka, Kristiina Joensuu, Mine Eray and P äivi Heikkilä Tags: Research Source Type: research
Non-producer multiple myeloma presenting with acute hyperammonemic encephalopathy: case report
Hyperammonemic encephalopathy (HE) is a rare and life-threatening complication of multiple myeloma, with underlying mechanisms that are not fully understood. In contrast to previously reported cases, most of w... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - January 4, 2023 Category: Pathology Authors: Karina Verma, Tina Zhang, David Mueller, Julie Li, Vaishali Sanchorawala and Andrew Staron Tags: Case Report Source Type: research
Barium Sulfate Deposition in the Gastrointestinal Tract: Review of the literature
Barium sulfate is utilized for imaging of the gastrointestinal tract and is usually not deposited within the wall of the intestine. It is thought that mucosal injury may allow barium sulfate to traverse the mu... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - December 31, 2022 Category: Pathology Authors: Daniel J. Zaccarini, David Lubin, Soma Sanyal and Jerrold L. Abraham Tags: Review Source Type: research
High Hepcidin expression predicts poor prognosis in patients with clear cell renal cell carcinoma
Clear cell renal cell carcinoma (ccRCC) is a growing public health challenge worldwide. Hepcidin antimicrobial peptide (HAMP) is differentially expressed in various tumors. However, the roles and functions of ... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - December 31, 2022 Category: Pathology Authors: Yuting Tang, Shengdong Ge, Xiao Zheng and Jiejiao Zheng Tags: Research Source Type: research
Clinicopathological features and genomic profiles of a group of secretory breast carcinomas in which progressive cases have more complex genomic features
Secretory breast carcinoma (SBC) is a rare malignant breast neoplasm with distinct histological features, including solid, microcystic, tubular, and rarely papillary structures, traditionally characterized by ... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - December 31, 2022 Category: Pathology Authors: Ting Lei, Yuyan Yang, Yongqiang Shi, Xu Deng, Yan Peng, Hui Wang and Tongbing Chen Tags: Research Source Type: research
Proliferative epithelial changes in tumour adjacent tissue in Sri Lankan women with breast carcinoma: do morphological changes support molecular models of breast carcinogenesis?
The multistep molecular model of breast carcinogenesis is based on the oestrogen receptor(ER) status of the tumour. Its two main arms comprise ER-positive and ER-negative breast carcinomas(BCa), which are asso... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - December 29, 2022 Category: Pathology Authors: Indumini Maheshika Jinadasa, Harshima Disvini Wijesinghe, Modini Manohari Abeydera Jayawickrama and Menaka Dilani Samarawickrama Lokuhetty Tags: Research Source Type: research
Diagnostic pitfalls: a case of prostate cancer and rectal cancer accompanied by prostate cancer invasion of the rectum
Case of double primary cancer of the prostate and rectum is rare, prostate cancer involving the postoperative intestinal anastomotic mucosal tissue is even rarer. (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - December 29, 2022 Category: Pathology Authors: Qiongxian Long, Ji Wu, Yong Peng, Xuqian Zhang, Xinya Liu and Huaping Chen Tags: Case Report Source Type: research
Intraductal oncocytic papillary neoplasm arising in Peutz-Jeghers Syndrome bile duct: a unique case report
Peutz-Jeghers syndrome (PJS) is a rare, autosomal dominant disorder caused by germline mutations of STK11/LKB1, with an increased risk of tumors at multiple sites. Intraductal oncocytic papillary neoplasm (IOPN) ... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - December 28, 2022 Category: Pathology Authors: Qingyue Liu, Zhiyu Wang, Chaoran Yu, Jianping Zhu, Chengli Liu, Xiangsheng Li, Li Ren and Teng Li Tags: Case Report Source Type: research
Ureteral tumor with morphological features analogous to phyllodes tumor: a unique case with concomitant urothelial carcinoma
Phyllodes tumors belong to a spectrum of biphasic fibroepithelial lesions and are most commonly found in the breast. They are extremely rare in the urinary tract and only one case of bladder phyllodes tumor ha... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - December 23, 2022 Category: Pathology Authors: Wei Zhou, Linlin Dang, Chuangang Chong, Xiankui Cheng, Yejun Qin and Wenjing Su Tags: Case Report Source Type: research
Sinonasal mucosal melanoma with smooth muscle differentiation: a potential pathological diagnostic pitfall
Sinonasal mucosal melanoma (SNMM) is a rare malignant melanoma originating from melanocytes derived from multipotent neural crest cells. Its incidence accounts for less than 1 % of all malignant melanomas, wit... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - December 23, 2022 Category: Pathology Authors: Hao Tang, Yutao He, Ying Chen, Wenfeng Xu, Yujuan Xu, Xianyun Li and Deyu Guo Tags: Case Report Source Type: research
Comprehensive genomic profiling of a unique liposarcoma arising in a patient with Li –Fraumeni syndrome and the novel detection of c-myc amplification: a case report
Germline TP53 mutations have been frequently reported in patients with Li –Fraumeni syndrome (LFS), resulting in a predisposition to various malignancies. Mutations other than germline TP53 mutations can also caus... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - December 13, 2022 Category: Pathology Authors: Hirofumi Watanabe, Fumiyoshi Fujishima, Toru Motoi, Yayoi Aoyama, Tetsuya Niihori, Masanobu Takahashi, Sho Umegaki, Hisashi Oishi, Hiroshi Tada, Ryo Ichinohasama and Hironobu Sasano Tags: Case Report Source Type: research
p53 immunostaining pattern is a useful surrogate marker for TP53 gene mutations
TP53 is the most frequently mutated gene in the human cancer, and the awareness of its mutational status is useful in the diagnosis and treatment of cancer patients. In the present study, we investigated the asso... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - December 5, 2022 Category: Pathology Authors: You-Na Sung, Deokhoon Kim and Jihun Kim Tags: Research Source Type: research
Evaluation of tumor-infiltrating lymphocytes (TILs) in molecular subtypes of an Indian cohort of breast cancer patients
Evaluation of tumor-infiltrating lymphocytes (TILs) distribution in an Indian cohort of breast cancer patients for its prognostic significance. (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - November 21, 2022 Category: Pathology Authors: Pooja M. Vaid, Anirudha K. Puntambekar, Nutan S. Jumle, Rituja A. Banale, Danish Ansari, Ruhi R. Reddy, Rohini R. Unde, Namrata P. Namewar, Devaki A. Kelkar, L. S. Shashidhara, Chaitanyanand B. Koppiker and Madhura D. Kulkarni Tags: Research Source Type: research
Aberrant synaptophysin expression in classic Hodgkin lymphoma
Synaptophysin is an immunohistochemical marker for neuroendocrine differentiation and is widely used in pathologic diagnosis. Its expression in malignant lymphoma has not yet been described. However, we experi... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - November 18, 2022 Category: Pathology Authors: Soyoung Im, Jeong-A. Kim, Gyeongsin Park and Uiju Cho Tags: Research Source Type: research
Multidisciplinary collaboration in diagnosis and treatment of neuroleptic malignant syndrome complicated with pneumonia: report of three cases
Neuroleptic malignant syndrome (NMS) is a relatively rare and a potentially fatal syndrome. It is a serious complication associated with antipsychotic therapy. NMS is easily prone to pneumonia, rhabdomyolysis ... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - November 9, 2022 Category: Pathology Authors: Huachang Zhao, Sijia Lu, Xiaoyan Li, Panyun Huang, Hongming Wang and Fengmei Lu Tags: Case Report Source Type: research
