Explainable convolutional neural networks for assessing head and neck cancer histopathology
Although neural networks have shown remarkable performance in medical image analysis, their translation into clinical practice remains difficult due to their lack of interpretability. An emerging field that ad... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - November 3, 2023 Category: Pathology Authors: Marion D örrich, Markus Hecht, Rainer Fietkau, Arndt Hartmann, Heinrich Iro, Antoniu-Oreste Gostian, Markus Eckstein and Andreas M. Kist Tags: Research Source Type: research
Bilateral ovarian fibromas as the sole manifestation of Gorlin syndrome in a 22-year-old woman: a case report and literature review
Nevoid basal cell carcinoma syndrome (NBCCS, Gorlin syndrome) is a rare autosomal dominantly inherited disorder that is characterized by multisystem disorder such as basal cell carcinomas, keratocystic odontog... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - October 31, 2023 Category: Pathology Authors: Menghan Zhu, Jun Li, Jie Duan, Jing Yang, Weiyong Gu and Wei Jiang Tags: Case Report Source Type: research
Penile melanoma: a pathological report of two cases
Penile melanoma (PM) is a rare tumor, accounting for less than 2% of all penile cancers. PM can occur on the surface of the glans, foreskin, and opening of the urethra. Furthermore, PM primarily affects older ... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - October 28, 2023 Category: Pathology Authors: Bogl árka Pósfai, Márton Szentkereszty, Fanni Sánta, Zoltán Bajory, Andrea Simon, Zsófia Kozéki, Ildikó Csányi, Mahmut Akgul and Levente Kuthi Tags: Case Report Source Type: research
Identification of dual STRN-NTRK2 rearrangements in a high grade sarcoma, with good clinical response to first-line larotrectinib therapy
Among the three NTRK genes, NTRK2 possesses a tremendous structural complexity and involves tumorigenesis of several types of tumors. To date, only STRN and RBPMS are identified in the fusion with NTRK2 in adult ... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - October 21, 2023 Category: Pathology Authors: Ruihe Lin, Atrayee Basu Mallick, Zi-Xuan Wang, Scot Andrew Brown, Bo Lu and Wei Jiang Tags: Case Report Source Type: research
Circularity of islets is a distinct marker for the pathological diagnosis of adult non-neoplastic hyperinsulinemic hypoglycemia using surgical specimens
Adult non-neoplastic hyperinsulinemic hypoglycemia (ANHH), also known as adult-onset nesidioblastosis, is a rare cause of endogenous hyperinsulinemic hypoglycemia in adults. This disease is characterized by di... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - October 20, 2023 Category: Pathology Authors: Ryota Nakagawa, Sachiko Minamiguchi, Tatsuki R. Kataoka, Junji Fujikura, Toshihiko Masui, Masakazu Fujimoto, Yosuke Yamada, Yasuhide Takeuchi, Yuki Teramoto, Hiroaki Ito, Manduwa Saka, Kyohei Kitamura, Shinya Otsuki, Ryohei Nishijima and Hironori Haga Tags: Research Source Type: research
Invasive stratified mucin-producing carcinoma of the colorectum: expanding the morphologic spectrum of large bowel cancer
Invasive stratified mucin-producing carcinoma is a recently recognized adenocarcinoma with distinctive features. It was first described in the cervix but similar tumors have since been reported in the penis, a... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - October 18, 2023 Category: Pathology Authors: Finn Morgan Auld and Terence N. Moyana Tags: Research Source Type: research
Evidence of autoinflammation as a principal mechanism of myocardial injury in SARS-CoV-2 PCR-positive medical examiner cases
Disease from Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) remains the seventh leading cause of death in the United States. Many patients infected with this virus develop later cardiovascular co... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - October 18, 2023 Category: Pathology Authors: Margo E. Hammond, Erik D. Christensen, Michael Belenky, Gregory L. Snow, Kevin Shah and M. Elizabeth H. Hammond Tags: Research Source Type: research
Adrenal schwannoma can be FDG-Avid on PET/CT: case report and review of historic institutional pathology
Schwannomas are benign, generally indolent tumors of neural crest origin and comprise the most common histologic tumor of peripheral nerves. Schwannomas are a rare histology for retroperitoneal tumors and very... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - October 13, 2023 Category: Pathology Authors: Oliver J. Fackelmayer, Eduardo D. Rodriguez, Anthony E. Sisk Jr and Masha J. Livhits Tags: Case Report Source Type: research
Possible Concomitant Aggressive NK Cell Leukemia and EBV-positive T-cell lymphoma; Using the online beta version of WHO-HAEM5 and videoconferencing software to make diagnoses accessible in an emerging economy
Using the World Health Organization Classification 5th edition (beta version online; WHO-HAEM5bv) in emerging economies is key to global healthcare equity. Although there may be ongoing updates, hesitancy in a... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - October 6, 2023 Category: Pathology Authors: Vanessa J. Dayton, Dang Hoang Thien, Phan Thi Xinh, Cade Arries, Nguyen Ngoc Sang, Ngo Ngoc Ngan Linh, Nguyen Phuong Lien and Phu Chi Dung Tags: Case Report Source Type: research
Artificial intelligence in diagnostic pathology
Digital pathology (DP) is being increasingly employed in cancer diagnostics, providing additional tools for faster, higher-quality, accurate diagnosis. The practice of diagnostic pathology has gone through a s... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - October 3, 2023 Category: Pathology Authors: Saba Shafi and Anil V. Parwani Tags: Review Source Type: research
Jejunal gastrointestinal stromal tumor that developed in a patient with neurofibromatosis type 1: a case report
Neurofibromatosis type 1 (NF1) is known to be associated with the frequent occurrence of unique gastrointestinal stromal tumors (GISTs), preferably occurring in the small intestine, with no mutations in the c-kit (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - October 3, 2023 Category: Pathology Authors: Hideki Nagano, Shigekazu Ohyama, Atsushi Sato, Jun Igarashi, Tomoko Yamamoto, Masumi Kadoya and Mikiko Kobayashi Tags: Case Report Source Type: research
Effect and mechanism of HMG-CoA reductase inhibitor on the improvement of elderly essential hypertension-induced vascular endothelial function impairment based on the JAK/STAT pathway
Our research was designed to figure out the influence and mechanism of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor on the improvement of elderly essential hypertension-induced vascular ... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - September 28, 2023 Category: Pathology Authors: Wen Yuan, Hongjun Fan, Haibing Yang, Liang Tang, Zhiming Liu, Fan Ouyang, Wei Luo and Yong Yan Tags: Research Source Type: research
Successful neoadjuvant chemotherapy plus sintilimab for locally advanced cervical cancer: case series and review of the literature
The locally advanced cervical cancer (LACC) of FIGO stage IB3-IIA2 is characterized by large local mass, poor prognosis and survival rate. Tumor response to neoadjuvant chemotherapy for LACC, utilized as a sur... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - September 26, 2023 Category: Pathology Authors: Linlin Liu, Xianbo Deng, Shuang Guo and Shouhua Yang Tags: Case Report Source Type: research
MCM4 expression is associated with high-grade histology, tumor progression and poor prognosis in urothelial carcinoma
We previously reported Minichromosome maintenance 4 (MCM4) overexpression in gastric cancer. However, the clinicopathological significance of MCM4 in urothelial carcinoma (UC) has not been investigated. To cla... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - September 22, 2023 Category: Pathology Authors: Go Kobayashi, Tetsutaro Hayashi, Kazuhiro Sentani, Naohiro Uraoka, Takafumi Fukui, Aya Kido, Narutaka Katsuya, Akira Ishikawa, Takashi Babasaki, Yohei Sekino, Hiroyuki Nose, Koji Arihiro, Nobuyuki Hinata and Naohide Oue Tags: Research Source Type: research
A novel TPD52L2-ROS1 gene fusion expanding the molecular alterations in inflammatory myofibroblastic tumor: case report and literature review
Inflammatory myofibroblastic tumor (IMT) is a distinctive tumor composed of spindle cells accompanied by mixed inflammatory cells, and immunohistochemical positivity for ALK (anaplastic lymphoma kinase protein... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - September 21, 2023 Category: Pathology Authors: Xuguang Liu, Yaqi Duan, Guoping Wang and Pengcheng Zhu Tags: Case Report Source Type: research
