Lymph node ratio is a more robust predictor of overall survival than N stage in stage III colorectal adenocarcinoma
Lymph node ratio (LNR) may offer superior prognostic stratification in colorectal adenocarcinoma compared with N stage. However, candidate cutoff ratios require validation. We aimed to study the prognostic sig... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - February 28, 2024 Category: Pathology Authors: Amir F. Beirat, Justin Z. Amarin, Haya H. Suradi, Yasmeen Z. Qwaider, Adel Muhanna, Bayan Maraqa, Abdallah Al-Ani and Maysa Al-Hussaini Tags: Research Source Type: research

Challenges and barriers of using large language models (LLM) such as ChatGPT for diagnostic medicine with a focus on digital pathology – a recent scoping review
The integration of large language models (LLMs) like ChatGPT in diagnostic medicine, with a focus on digital pathology, has garnered significant attention. However, understanding the challenges and barriers as... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - February 27, 2024 Category: Pathology Authors: Ehsan Ullah, Anil Parwani, Mirza Mansoor Baig and Rajendra Singh Tags: Review Source Type: research

Quantitative assessment of H & E staining for pathology: development and clinical evaluation of a novel system
Staining tissue samples to visualise cellular detail and tissue structure is at the core of pathology diagnosis, but variations in staining can result in significantly different appearances of the tissue sampl... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - February 23, 2024 Category: Pathology Authors: Catriona Dunn, David Brettle, Martin Cockroft, Elizabeth Keating, Craig Revie and Darren Treanor Tags: Research Source Type: research

Histopathology and molecular pathology confirmed a diagnosis of atypical Caroli ’s syndrome: a case report
Caroli ’s syndrome is a congenital disease characterized by dilation of intrahepatic bile ducts and congenital hepatic fibrosis. It is a rare condition in clinical work. Typically, the diagnosis of this disease... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - February 22, 2024 Category: Pathology Authors: Tianmin Zhou, Keyu Liu, Hao Wei, Qingmei Zhong, Daya Luo, Wenjuan Yang, Ping Zhang and Yingqun Xiao Tags: Case Report Source Type: research

Artificial intelligence ’s impact on breast cancer pathology: a literature review
This review discusses the profound impact of artificial intelligence (AI) on breast cancer (BC) diagnosis and management within the field of pathology. It examines the various applications of AI across diverse... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - February 22, 2024 Category: Pathology Authors: Amr Soliman, Zaibo Li and Anil V. Parwani Tags: Review Source Type: research

Clinicopathological analysis of rosette-forming glioneuronal tumors
This study aimed to investigate the clinicopathological characteristics, diagnostic indicators, and critical factors for the differential diagnosis of rosette-forming glioneuronal tumor (RGNT). (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - February 22, 2024 Category: Pathology Authors: Jing Liu, Fan Lin, Yanhua Sun and Xia Liu Tags: Case Report Source Type: research

A case of fat-forming solitary fibrous tumor that is prone to be confused with liposarcoma
Fat-forming solitary fibrous tumor is a rare and specific subtype of solitary fibrous tumor. In this case, a mass of 8.3 cm in diameter was found in a 59-year-old male patient ’s right retroperitoneum, as revea... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - February 22, 2024 Category: Pathology Authors: Yi-Dan Ma, Zi-Qing Wu, Xin-Rong Liang, Lin Jing Pi, Meng-Zhen Gong and Yao Tang Tags: Case Report Source Type: research

A case report of abdominal metastatic dermatofibrosarcoma protuberans misdiagnosed as gastrointestinal stromal tumor
Dermatofibrosarcoma protuberans (DFSP) is a low-grade malignant soft-tissue tumor that originates from the skin. It has a slow onset in the early stages, non-specific clinical symptoms, low specificity, and ca... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - February 22, 2024 Category: Pathology Authors: Minying Deng, Qingxiao Liu, Lei Ren, Wei Yuan, Chen Xu and Yingyong Hou Tags: Case Report Source Type: research

Epstein-Barr virus-positive inflammatory follicular dendritic cell sarcoma with significant granuloma: case report and literature review
Epstein-Barr virus-positive inflammatory follicular dendritic cell sarcoma (EBV+IFDCS) is a rare disease characterized by mild clinical symptoms and non-specific imaging findings. The diagnosis of the disease ... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - February 16, 2024 Category: Pathology Authors: Chenchen Nie, Xun Xie, Hangyan Li, Yangcan Li, Zhihong Chen, Yanchun Li and Zhenfeng Li Tags: Case Report Source Type: research

Evaluating the effects of curcumin nano-chitosan on miR-221 and miR-222 expression and Wnt/ β-catenin pathways in MCF-7, MDA-MB-231 and SKBR3 cell lines
Breast cancer is one of the most common diseases worldwide that affects women of reproductive age. miR-221 and miR-222 are two highly homogeneous microRNAs that play pivotal roles in many cellular processes and r... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - February 16, 2024 Category: Pathology Authors: Touba Eslaminejad, Seyed Noureddin Nematollahi-Mahani, Marzieh Lotfian Sargazi, Mehdi Ansari and Vida Mirzaie Tags: Research Source Type: research

Clinical application of the HM-1000 image processing for HER2 fluorescence in situ hybridization signal quantification in breast cancer
Accurate quantification of human epidermal growth factor receptor 2 (HER2) gene amplification is important for predicting treatment response and prognosis in patients with breast cancer. Fluorescence in situ hybr... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - February 15, 2024 Category: Pathology Authors: Vicente Peg, Teresa Moline, Miquel Roig, Yuko Saruta and Santiago Ramon y Cajal Tags: Research Source Type: research

Acute neutrophilic vasculitis (leukocytoclasia) in 36 COVID-19 autopsy brains
Hypercytokinemia, the renin-angiotensin system, hypoxia, immune dysregulation, and vasculopathy with evidence of immune-related damage are implicated in brain morbidity in COVID-19 along with a wide variety of... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - February 15, 2024 Category: Pathology Authors: Roy H. Rhodes, Gordon L. Love, Fernanda Da Silva Lameira, Maryam Sadough Shahmirzadi, Sharon E. Fox and Richard S. Vander Heide Tags: Research Source Type: research

Novel KMT2B gene mutation in MUC4 positive low-grade fibromyxoid sarcoma
Low-grade Fibromyxoid Sarcoma(LGFM)is a rare fibrosarcoma, which mainly occurs in young people and is mostly seen in the trunk and limbs. The tumor is usually FUS-CREB3L2 fusion cause... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - February 12, 2024 Category: Pathology Authors: Liying Zhang, Luqiao Luo, Chao Liu and Zhi Li Tags: Case Report Source Type: research

The court ’s judgment on the true identity of the author responsible for identity fraud and the consequent batch retraction of Iranian’s papers in the journal of diagnostic pathology
This letter concerns retracted papers published in the Journal of Diagnostic Pathology, where my name was misused as the author or corresponding author without my permission or knowledge. Considering that all ... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - February 12, 2024 Category: Pathology Authors: Aram Mokarizadeh Tags: Comment Source Type: research

Killing capacity analysis of tumor-infiltrating cytotoxic lymphocytes and impact on lymph node metastasis in differentiated papillary carcinoma of thyroid with the BRAF V600E mutation
Cytotoxic lymphocytes (CLs) express potent toxins, including perforin (P) and granzyme-B (G), which brings about target cell death. The purpose of this study was to evaluate the killing capacity of tumor-infil... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - February 10, 2024 Category: Pathology Authors: Xiaogang Liu, Honggang Liu, Lu Wang, Yubing Han, Linghong Kong and Xinpeng Zhang Tags: Research Source Type: research