Stromal osseous metaplasia in urothelial carcinoma of the bladder: a rare case report and literature review
The bone formation within bladder tumors could be encountered in 3 conditions. These might consist of malignant bone formation in mesenchymal tumors; mixed mesenchymal and epithelial tumors; and epithelial tum... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - July 13, 2019 Category: Pathology Authors: Jo ëlle Razafimahefa, Clément Gosset, Pierre Mongiat-Artus, Tsitohery Francine Andriamampionona and Jérôme Verine Tags: Case Report Source Type: research

Prenatal diagnosis of fetal skeletal dysplasia using targeted next-generation sequencing: an analysis of 30 cases
This study aims to provide genetic diagnoses for 30 cases of fetal skeletal dysplasia, and a molecular basis for the future prenatal diagnosis of fetal skeletal dysplasia. (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - July 13, 2019 Category: Pathology Authors: Yan Liu, Li Wang, Yi-Ke Yang, Ying Liang, Tie-Juan Zhang, Na Liang, Li-Man Yang, Si-Jing Li, Dan Shan and Qing-Qing Wu Tags: Research Source Type: research

Relevance and clinicopathologic relationship of BRAF V600E, TERT and NRAS mutations for papillary thyroid carcinoma patients in Northwest China
To determine the relevance of the single or combination mutations of BRAF V600E, TERT, and NRAS genes and the clinicopathologic relationship in papillary thyroid cancer (PTC). (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - July 12, 2019 Category: Pathology Authors: Meiling Huang, Changjiao Yan, Jingjing Xiao, Ting Wang and Rui Ling Tags: Research Source Type: research

Primary endocervical gastric-type adenocarcinoma: a clinicopathologic and immunohistochemical analysis of 23 cases
This study aime... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - July 6, 2019 Category: Pathology Authors: Shanshan Lu, Danhua Shen, Yun Zhao, Nan Kang and Xingxing Wang Tags: Research Source Type: research

Poorly differentiated mucinous carcinoma with signet ring cells in an ovarian endometriotic cyst: a case report
Ovarian signet ring cell carcinomas are predominantly metastatic. Cases coexisting with endometriotic cysts are extremely rare, and are supposed to be primary. However, such cases have not been well-documented... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - July 6, 2019 Category: Pathology Authors: Yurong Jiao and Bingjian Lu Tags: Case Report Source Type: research

Mesonephric adenocarcinoma of the cervix: a case report with a three-year follow-up, lung metastases, and next-generation sequencing analysis
Mesonephric adenocarcinoma (MNAC) is a rare tumor of the female genital tract, which originates from mesonephric duct remnants. Its diagnosis is pathologically challenging, because MNAC may exhibit a mixture o... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - July 3, 2019 Category: Pathology Authors: Nelson Montalvo, Ligia Redrob án and David Galarza Tags: Case Report Source Type: research

BCL2 overexpression: clinical implication and biological insights in acute myeloid leukemia
BCL2 protein inhibitor venetoclax (ABT-199) has been authorized by Food and Drug Administration for relapsed/refractory chronic lymphoid leukemia with 17p deletion. Although venetoclax/ABT-199 also caused cell de... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - June 29, 2019 Category: Pathology Authors: Jing-dong Zhou, Ting-juan Zhang, Zi-jun Xu, Yu Gu, Ji-chun Ma, Xi-xi Li, Hong Guo, Xiang-mei Wen, Wei Zhang, Lei Yang, Xing-hui Liu, Jiang Lin and Jun Qian Tags: Research Source Type: research

Diagnostic terminology used to describe atypia on breast core needle biopsy: correlation with excision and upgrade rates
Subjective qualitative descriptors are sometimes used to describe atypical breast lesions diagnosed on core needle biopsy (CNB) which are limited in extent. In clinical practice, this terminology is used to im... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - June 29, 2019 Category: Pathology Authors: Gary Tozbikian, Michael George and Debra L. Zynger Tags: Research Source Type: research

Hyaline vascular variant of unicentric Castleman disease of the tonsil: a case report
Castleman disease (CD) is a lymphoproliferative disorder with an unknown etiology. The disease may be unicentric (UCD) or multicentric (MCD), and three histopathologic variants have been described: hyaline vas... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - June 29, 2019 Category: Pathology Authors: Ping Li, Huaipu Liu, Hao Li, Ang Li, Guangyin Yu and Weihua Yin Tags: Case Report Source Type: research

Case report: mutation analysis of primary pulmonary lymphoepithelioma-like carcinoma via whole-exome sequencing
Primary pulmonary lymphoepithelioma-like carcinoma (LELC) is a rare tumor subtype accounting for around 0.9% of lung cancers. At present, research on LELC mainly focuses on pathological diagnosis, while the mo... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - June 28, 2019 Category: Pathology Authors: Hong Xuan, Chai Zhengjun, Han Yang and Chen Guohan Tags: Case Report Source Type: research

Validation of mitotic cell quantification via microscopy and multiple whole-slide scanners
The establishment of whole-slide imaging (WSI) as a medical diagnostic device allows that pathologists may evaluate mitotic activity with this new technology. Furthermore, the image digitalization provides an ... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - June 26, 2019 Category: Pathology Authors: Kazuhiro Tabata, Naohiro Uraoka, Jamal Benhamida, Matthew G. Hanna, Sahussapont Joseph Sirintrapun, Brandon D. Gallas, Qi Gong, Rania G. Aly, Katsura Emoto, Kant M. Matsuda, Meera R. Hameed, David S. Klimstra and Yukako Yagi Tags: Research Source Type: research

Primary pseudomyogenic hemangioendothelioma of the vulva: a rare location for a rare entity
Pseudomyogenic hemangioendothelioma (PMHE) is a recently described vascular neoplasm which typically occurs in the lower extremities of young to middle-aged adults. (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - June 26, 2019 Category: Pathology Authors: Yue-Fang Sun and Jian Wang Tags: Case Report Source Type: research

Cystic appearance - a new feature of solid fibrous tumours in the lacrimal gland: a case report with literature review
Solitary fibrous tumours (SFTs) rarely occur in the orbit, especially in the lacrimal area. These tumours are mostly solid. Cystic changes have been documented, but they remain very rare. Only three cases of p... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - June 22, 2019 Category: Pathology Authors: Ancuta-Augustina Gheorghisan-Galateanu, Dana Cristina Terzea, Iulia Burcea, Roxana Dusceac, Cristina Capatina and Catalina Poiana Tags: Case Report Source Type: research

Clinicopathological characteristics and molecular abnormalities of primary grade 2 neuroendocrine tumors of the cervix
This study is aimed to analyse the diagnosis, genetic changes, management and progn... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - June 22, 2019 Category: Pathology Authors: Ran Zhu, Huanwen Wu, Bo Chen, Junyi Pang and Zhen Huo Tags: Research Source Type: research

The importance of EGFR mutation testing in squamous cell carcinoma or non-small cell carcinoma favor squamous cell carcinoma diagnosed from small lung biopsies
Adenosquamous carcinoma (ADSC) of the lung, a rare but aggressive subtype of non-small cell lung cancer (NSCLC), is defined as a carcinoma containing components of adenocarcinoma (ADC) and squamous cell carcin... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - June 21, 2019 Category: Pathology Authors: Hsiang-Ling Ho, Hua-Lin Kao, Yi-Chen Yeh and Teh-Ying Chou Tags: Research Source Type: research

High expression of MRE11 correlates with poor prognosis in gastric carcinoma
MRE11, a protein known to play a vital role in DNA double-strand break repair, is associated with the prognosis of a variety of tumours, but there are few studies regarding the role of MRE11 in gastric carcino... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - June 21, 2019 Category: Pathology Authors: Junqing Li, Taiqiang Su, Liang Yang, Changhua Zhang and Yulong He Tags: Research Source Type: research

Expression of GCRG213p, LINE-1 endonuclease variant, significantly different in gastric complete and incomplete intestinal metaplasia
Intestinal metaplasia (IM) of the gastric mucosa is classified as complete (Type I) and incomplete IM (Type II and III) subtypes, which showed significantly different risk for developing to gastric adenocarcin... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - June 21, 2019 Category: Pathology Authors: Xiaojian Duan, Hongwei Lian, Jie Li, Benyan Wu, Weihua Wang, Tao Wu, Changzheng Wang, Yan Dou, Zhongren Zhou, Bingzhi Wang, Liyan Xue and Gangshi Wang Tags: Research Source Type: research

Off-label use of common predictive biomarkers in gastrointestinal malignancies: a critical appraisal
The use of immunohistochemistry (IHC) as a companion diagnostic is an increasingly important part of the case workup by pathologists and is often central to clinical decision making. New predictive molecular m... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - June 21, 2019 Category: Pathology Authors: Basile Tessier-Cloutier, Ellen Cai and David F. Schaeffer Tags: Review Source Type: research

Comparative analysis of confocal microscopy on fresh breast core needle biopsies and conventional histology
Evaluation of core needle biopsies (CNB) is a standard procedure for the diagnosis of breast cancer. However, tissue processing and image preparation is a time- consuming procedure and instant on-site availabi... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - June 15, 2019 Category: Pathology Authors: C. Elfgen, B. Papassotiropoulos, Z. Varga, L. Moskovszky, M. Nap, U. G üth, A. Baege, E. Amann, F. Chiesa and C. Tausch Tags: Research Source Type: research

Improving sensitivity of amyloid detection by Congo red stain by using polarizing microscope and avoiding pitfalls
Systemic amyloidosis is a devastating group of disorders for which there is no current cure. The treatment goal is to reduce the burden of amyloidogenic protein precursors. The treatment is only effective if a... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - June 14, 2019 Category: Pathology Authors: Ashraf El-Meanawy, Christopher Mueller and Kenneth A. Iczkowski Tags: Short report Source Type: research

Treatment outcome and prognostic factors in PCNSL
Standard treatment with a thiotepa-based regimen in countries with a limited resource is less feasible. Aims of the study were to evaluate the treatment outcome, and identify the prognostic factors in patients... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - June 13, 2019 Category: Pathology Authors: Pimjai Niparuck, Paisarn Boonsakan, Taksayut Sutthippingkiat, Sulada Pukiat, Pichika Chantrathammachart, Sithakom Phusanti, Kochawan Boonyawat, Teeraya Puavilai, Pantep Angchaisuksiri, Artit Ungkanont, Suporn Chuncharunee and Vichai Atichartakarn Tags: Research Source Type: research

Association of tumour-associated macrophages with cancer cell EMT, invasion, and metastasis of Kazakh oesophageal squamous cell cancer
Tumour-associated macrophages (TAMs) play an important role in the growth, progression, and metastasis of tumours. Epithelial-mesenchymal transition (EMT) is a mechanism for tumour invasion and metastasis. In ... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - June 12, 2019 Category: Pathology Authors: Jihong Liu, Chunxiao Li, Liyan Zhang, Kai Liu, Xianli Jiang, Xueli Wang, Lan Yang, Weihua Liang, Kunping Liu, Jianming Hu and Feng Li Tags: Research Source Type: research

Coexistence of endometrial mesonephric-like adenocarcinoma and endometrioid carcinoma suggests a M üllerian duct lineage: a case report
Endometrial mesonephric-like adenocarcinomas exhibit classical histologic features of mesonephric carcinoma; however, it remains unclear whether these tumors represent mesonephric (Wolffian) carcinoma or endom... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - June 7, 2019 Category: Pathology Authors: Mitsutake Yano, Daisuke Shintani, Tomomi Katoh, Mei Hamada, Kozue Ito, Eito Kozawa, Kosei Hasegawa and Masanori Yasuda Tags: Case Report Source Type: research

Overexpression of microRNA-423-3p indicates poor prognosis and promotes cell proliferation, migration, and invasion of lung cancer
Lung cancer is one of the common malignant tumors worldwide with high incidence and mortality. MicroRNA-423-3p (miR-423-3p) acts as an oncogene in several types of cancers. The aim of this study is to reveal t... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - June 4, 2019 Category: Pathology Authors: Rukun Wang, Gaofeng Li, Guoyan Zhuang, Shuying Sun and Zhihui Song Tags: Research Source Type: research

IL-17A increases MHC class I expression and promotes T cell activation in papillary thyroid cancer patients with coexistent Hashimoto ’s thyroiditis
The incidence of coexisting papillary thyroid cancer (PTC) and Hashimoto ’s thyroiditis (HT) is increasing. The impact of HT on PTC prognosis and its possible mechanism remains controversial. Interleukin-17A (I... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - June 4, 2019 Category: Pathology Authors: Li-Tao Han, Jia-Qian Hu, Ben Ma, Duo Wen, Ting-Ting Zhang, Zhong-Wu Lu, Wen-Jun Wei, Yu-Long Wang, Yu WANG, Tian Liao and Qing-Hai Ji Tags: Research Source Type: research

Primary intraosseous hybrid epithelioid schwannoma/perineurioma in the proximal tibia: a case report of benign hybrid neoplasm with local hypercellularity
As a new entity included in the 4th edition of the WHO classification of tumours of soft tissue and bone in 2013, hybrid peripheral nerve sheath tumours are benign composite neoplasms that demonstrate features... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - June 1, 2019 Category: Pathology Authors: Yuejiao Lang, Dawei Liu, Pei Xiang, Jilin Wang and Yang Li Tags: Case Report Source Type: research

Expression of Concern to: Decreased microRNA-224 and its clinical significance in non-small cell lung cancer patients
. (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - May 30, 2019 Category: Pathology Authors: Dan Zhu, Hui Chen, Xiguang Yang, Weisong Chen, Linying Wang, Jilin Xu and Long Yu Tags: Correction Source Type: research

Serum expression of selected miRNAs in patients with laryngeal squamous cell carcinoma (LSCC)
The aim of the present study was to identify specific serum miRNAs (preoperative serum samples compared to healthy controls) as potential diagnostic markers for detection in laryngeal squamous cell carcinoma (... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - May 28, 2019 Category: Pathology Authors: Weronika Lucas Grzelczyk, Janusz Szemraj, Sylwia Kwiatkowska and Magdalena J ózefowicz-Korczyńska Tags: Research Source Type: research

Interobserver variability and accuracy of p16/Ki-67 dual immunocytochemical staining on conventional cervical smears
p16/Ki-67 dual immunocytochemical staining (DS) has been proven as a sensitive and specific test for triage of HPV positive women with good reproducibility and accuracy. However, implementation of the test int... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - May 24, 2019 Category: Pathology Authors: Veronika Kloboves Prevodnik, Tine Jerman, Nata ša Nolde, Alenka Repše Fokter, Sandra Jezeršek, Živa Pohar Marinšek, Ulrika Klopčič, Simona Hutter Čelik, Kristina Gornik Kramberger, Maja Primic Žakelj and Urška Ivanuš Tags: Research Source Type: research

Tumor-to-tumor metastasis: a rare case of breast carcinoma metastasizing to a pheochromocytoma, and a literature review
Tumor-to-tumor metastasis is a well-recognized but uncommon entity. Breast carcinoma is one of the most common metastatic donors. Breast carcinoma metastasizes commonly to adrenal glands. However, the co-exist... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - May 20, 2019 Category: Pathology Authors: Weiwei Tan, Lili Tao, Zhuping Zhou, Weihua Yin and Yaoli Chen Tags: Case Report Source Type: research

Comparison of four DLL3 antibodies performance in high grade neuroendocrine lung tumor samples and cell cultures
Small cell lung cancer (SCLC) is usually diagnosed in the advanced stage. It has a very poor prognosis, with no advancements in therapy in the last few decades. A recent phase 1 clinical study, using an antibo... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - May 20, 2019 Category: Pathology Authors: Luka Brcic, Christian Kuchler, Sylvia Eidenhammer, Daniela Pabst, Franz Quehenberger, Adi F. Gazdar and Helmut Popper Tags: Research Source Type: research

Retraction Note: RNAi targeting CXCR4 inhibits proliferation and invasion of esophageal carcinoma cells
The Editor-in-Chief has retracted this article [1] because Fig. 3 shows overlap with Fig. 6 in [2], Fig. 2b in [3] and Fig. 6a in [4]. An investigation by Zhengzhou University has confirmed that these figures ... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - May 20, 2019 Category: Pathology Authors: Tao Wang, Yanfang Mi, Linping Pian, Ping Gao, Hong Xu, Yuling Zheng and Xiaoyan Xuan Tags: Correction Source Type: research

Rare cases of primary central nervous system anaplastic variant of diffuse large B-cell lymphoma
Primary central nervous system (CNS) diffuse large B-cell lymphoma (DLBCL) is a rare intracranial tumor, defined as DLBCL arising from the brain, spinal cord, leptomeninges and eye, with an overall annual inci... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - May 20, 2019 Category: Pathology Authors: Tianqi Xu, Qingge Jia, Yingmei Wang, Yixiong Liu, Donghui Han, Peifeng Li, Jing Ma, Linni Fan, Qingguo Yan, Shuangping Guo, Mingyang Li and Zhe Wang Tags: Case Report Source Type: research

Desmoplastic small round cell tumor of the parotid gland-report of a rare case and a review of the literature
Desmoplastic small round cell tumor (DSRCT) is a rare soft tissue tumor that generally involves the retroperitoneum, pelvis, omentum and mesentery in younger patients. However, extra-abdominal DSRCT is very rare. (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - May 18, 2019 Category: Pathology Authors: Kanako C. Hatanaka, Emi Takakuwa, Yutaka Hatanaka, Akira Suzuki, Satoshi IIzuka, Nayuta Tsushima, Tomoko Mitsuhashi, Shintaro Sugita, Akihiro Homma, Shojiroh Morinaga, Tadashi Hashegawa and Yoshihiro Matsuno Tags: Case Report Source Type: research

A novel apolipoprotein E mutation caused by a five amino acid deletion in a Chinese family with lipoprotein glomerulopathy: a case report
Lipoprotein glomerulopathy (LPG) is a rare kidney disease with a poor prognosis that is related to mutation of the apoE gene. More than 10 variants of apoE associated with LPG have currently been identified. (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - May 15, 2019 Category: Pathology Authors: Weiji Xie, Yi Xie, Zhijun Lin, Xiaochang Xu and Yimin Zhang Tags: Case Report Source Type: research

Positive/retained SDHB immunostaining in renal cell carcinomas associated to germline SDHB-deficiency: case report
According to WHO, succinate dehydrogenase (SDH) –deficient renal cell carcinoma is characterized by negative immunostaining for SDHB, which remains positive in non-tumor tissue despite germline mutations in the SD... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - May 15, 2019 Category: Pathology Authors: Marina Ugarte-Camara, Raul Fernandez-Prado, Isabel Lorda, Gabriela Rossello, Carmen Gonzalez-Enguita, Pablo Cannata-Ortiz and Alberto Ortiz Tags: Case Report Source Type: research

Colon adenoma and adenocarcinoma with clear cell components - two case reports
Diagnoses reflect clear cell morphologies when tumor cells have clear cytoplasm in many organs, and the nature of such clear cells is typically identified. Colorectal tubular adenoma or adenocarcinoma, convers... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - May 10, 2019 Category: Pathology Authors: Yuzo Oyama, Haruto Nishida, Takahiro Kusaba, Hiroko Kadowaki, Motoki Arakane, Kazuhisa Okamoto, Junpei Wada, Shogo Urabe and Tsutomu Daa Tags: Case Report Source Type: research

Gastric mixed neuroendocrine-non-neuroendocrine neoplasm (MiNEN) with pancreatic acinar differentiation: a case report
Gastric mixed neuroendocrine-non-neuroendocrine neoplasms (MiNENs) are infrequently encountered in routine practice. Some gastric neuroendocrine carcinomas (NECs) have a variety of differentiation patterns; ho... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - May 10, 2019 Category: Pathology Authors: Yasuko Fujita, Noriyuki Uesugi, Ryo Sugimoto, Makoto Eizuka, Takayuki Matsumoto and Tamotsu Sugai Tags: Case Report Source Type: research

Mutation profiles of follicular thyroid tumors by targeted sequencing
One of the major challenges remaining in the classification of thyroid tumor is the determination of whether a nodule is benign or malignant. We aimed to characterize the mutational profiles of follicular thyr... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - May 10, 2019 Category: Pathology Authors: Huanli Duan, Xiaoding Liu, Xinyu Ren, Hui Zhang, Huanwen Wu and Zhiyong Liang Tags: Research Source Type: research

Updated Oxford classification and the international study of kidney disease in children classification: application in predicting outcome of Henoch-Sch önlein purpura nephritis
Henoch-Sch önlein purpura nephritis (HSPN) shares many similarities with IgA nephropathy. We aimed to analyze the predictive value of the International Study of Kidney Disease in Children (ISKDC) classification... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - May 10, 2019 Category: Pathology Authors: Xiaohan Huang, Lili Ma, Pingping Ren, Hongya Wang, Liangliang Chen, Haidongqin Han, Jianghua Chen and Fei Han Tags: Research Source Type: research

Low frequency of mismatch repair deficiency in gallbladder cancer
DNA mismatch repair (MMR) deficiency is a major pathway of genomic instability in cancer. It leads to the accumulation of numerous mutations predominantly at microsatellite sequences, a phenotype known as micr... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - May 8, 2019 Category: Pathology Authors: Benjamin Goeppert, Stephanie Roessler, Marcus Renner, Moritz Loeffler, Stephan Singer, Melina Rausch, Thomas Albrecht, Arianeb Mehrabi, Monika Nadja Vogel, Anita Pathil, Elena Czink, Bruno K öhler, Christoph Springfeld, Christian Rupp, Karl Heinz Weiss, Tags: Research Source Type: research

A nomogram for predicting the HER2 status in female patients with breast cancer in China: a nationwide, multicenter, 10-year epidemiological study
The concordance rate of human epidermal growth factor receptor 2 (HER2) status between core needle biopsy (CNB) and subsequent excisional biopsies of the same tumor varies from 81 to 96%, which may cause inapp... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - May 4, 2019 Category: Pathology Authors: Huimin Zhang, Peiling Xie, Zhuoying Li, Rong Huang, Weiliang Feng, Yanan Kong, Feng Xu, Lin Zhao, Qingkun Song, Jing Li, Baoning Zhang, Jinhu Fan, Youlin Qiao, Xiaoming Xie, Shan Zheng, Jianjun He & hellip; Tags: Research Source Type: research

SNW1 is a prognostic biomarker in prostate cancer
SNW1 is a nuclear receptor co-activator involved in splicing and transcription control, including androgen receptor signaling. Overexpression of SNW1 has been linked to adverse prognosis in different cancer ty... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - May 1, 2019 Category: Pathology Authors: Doris H öflmayer, Carla Willich, Claudia Hube-Magg, Ronald Simon, Dagmar Lang, Emily Neubauer, Frank Jacobsen, Andrea Hinsch, Andreas M. Luebke, Marie Christina Tsourlakis, Hartwig Huland, Markus Graefen, Alexander Haese, Hans Heinzer, Sarah Minner, Fran Tags: Research Source Type: research

Nuclear TFE3 expression is a diagnostic marker for Desmoid-type fibromatosis
Desmoid-type fibromatosis (DTF) is a lesion characterized by clonal proliferation of myofibroblasts, which exhibits an infiltrative growth pattern. It is necessary for them to be distinguished from other fibro... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - May 1, 2019 Category: Pathology Authors: Luting Zhou, Haimin Xu, Jun Zhou, Lei Dong, Peipei Zhang, Xiaoqun Yang and Chaofu Wang Tags: Research Source Type: research

Leiomyoma with KAT6B-KANSL1 fusion: case report of a rapidly enlarging uterine mass in a postmenopausal woman
Uterine leiomyomas, in contrast to sarcomas, tend to cease growth following menopause. In the setting of a rapidly enlarging uterine mass in a postmenopausal patient, clinical distinction of uterine leiomyoma ... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - April 25, 2019 Category: Pathology Authors: Alessandra J. Ainsworth, Nooshin K. Dashti, Taofic Mounajjed, Karen J. Fritchie, Jaime Davila, Rohini Mopuri, Rory A. Jackson, Kevin C. Halling, Jamie N. Bakkum-Gamez and J. Kenneth Schoolmeester Tags: Case Report Source Type: research

Metastatic low-grade endometrial stromal sarcoma of uterus presenting as a primary pancreatic tumor: case presentation and literature review
Metastatic tumors to the pancreas are uncommon, accounting for approximately 2% of pancreatic malignancies. The most common primary tumors to give rise to pancreatic metastases are carcinomas. (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - April 22, 2019 Category: Pathology Authors: Aoife J. McCarthy, Blaise A. Clarke, Ian McGilvray, Brendan C. Dickson, Korosh Khalili and Runjan Chetty Tags: Case Report Source Type: research

Cross-hybridization between HPV genotypes in the Linear Array Genotyping Test confirmed by Next-Generation Sequencing
Linear Array Genotyping Test (LA) is one of the gold standards used for Human Papillomavirus (HPV) genotyping, however, since its launching in 2006, new HPV genotypes are still being characterized with the use... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - April 22, 2019 Category: Pathology Authors: Cristina Artaza-Irigaray, Mar ía Guadalupe Flores-Miramontes, Dominik Olszewski, Verónica Vallejo-Ruiz, Laura Patricia Limón-Toledo, Cibeles Sánchez-Roque, Rocío Mayoral-Torres, Luis Felipe Jave-Suárez and Adriana Aguilar-Lemarroy Tags: Research Source Type: research

Applications of molecular neuro-oncology - a review of diffuse glioma integrated diagnosis and emerging molecular entities
Insights into the molecular underpinnings of primary central nervous system tumors have radically changed the approach to tumor diagnosis and classification. Diagnostic emphasis has shifted from the morphology... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - April 9, 2019 Category: Pathology Authors: Matthew D. Wood, Aaron M. Halfpenny and Stephen R. Moore Tags: Review Source Type: research

Orthokeratinized odontogenic cyst (OOC): Clinicopathological and radiological features of a series of 10 cases
Orthokeratinized Odontogenic Cyst (OOC) is a rare, developmental odontogenic cyst which was considered in the past to be a variant of Odontogenic keratocyst (OKC) later renamed as keratocystic odontogenic tumo... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - April 4, 2019 Category: Pathology Authors: Nasir Uddin, Maha Zubair, Jamshid Abdul-Ghafar, Zia Ullah Khan and Zubair Ahmad Tags: Research Source Type: research

Mesenteric extraovarian Sertoli-Leydig cell tumor without DICER1 hotspot mutation: a case report
Ovarian Sertoli-Leydig cell tumors (SLCTs) with androgenic manifestations harbor DICER1 mutations in 30 –60% of cases. Ovarian SLCTs without DICER1 hotspot mutations have been reported to exhibit elderly onset and... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - April 1, 2019 Category: Pathology Authors: Mitsumasa Osakabe, Chie Sato, Masamichi Suzuki, Ryo Sugimoto, Yasuko Fujita, Noriyuki Uesugi, Kazuyuki Ishida, Hiroaki Itamochi, Tsukasa Baba and Tamotsu Sugai Tags: Case Report Source Type: research