Future Directions Incorporating Novel Medications to Reduce Repeat Overdose
AbstractPurpose of reviewThe use of opioids has risen dramatically in the USA and led to an increase in opioid use disorders and deaths due to opioid-related overdoses. Current treatments for opioid use disorder are not without drawbacks, so that new treatments may be helpful in reducing opioid use. This paper reviews current pharmacologic treatments for opioid use disorder as well as emerging novel treatments that may change or improve approaches to treatment.Recent findingsThe current treatments for opioid use disorder are methadone, buprenorphine, and naltrexone. Of the three, methadone has been the most studied and lon...
Source: Current Treatment Options in Psychiatry - September 1, 2018 Category: Psychiatry Source Type: research

Thyroid Hormone Treatment of Mood Disorders
AbstractPurpose of reviewBoth excess and insufficient thyroid hormones can lead to depression that is generally reversible with adequate thyroid treatment. On the other hand, major depression is associated with subtle chronobiological hypothalamic-pituitary-thyroid (HPT) axis dysregulation and thyroid hormones can be an effective adjunct to antidepressant treatment. However, the links between HPT axis status and efficacy of thyroid hormone supplementation in depression remain to be further clarified.Recent findingsWhile generally, depressed patients are chemically euthyroid, most exhibit a chronobiological HPT axis dysregu...
Source: Current Treatment Options in Psychiatry - August 30, 2018 Category: Psychiatry Source Type: research

Risk Factors for Opioid Overdose
AbstractPurpose of ReviewOpioid overdoses have risen starkly over the last two decades in the USA and are now among the leading causes of overall mortality. This review summarizes the current literature on risk factors for overdose as well as public health solutions.Recent FindingsAlthough opioid overdose mortality is highest among men and non-Hispanic whites, the rate of death is rising more rapidly now among women and non-Hispanic blacks. Incarceration remains a significant risk factor for overdose death, especially in the first weeks upon reentry reflecting the absence of treatment in prisons and jails despite strong ev...
Source: Current Treatment Options in Psychiatry - July 25, 2018 Category: Psychiatry Source Type: research

Mobile App Tools for Identifying and Managing Mental Health Disorders in Primary Care
AbstractPurpose of ReviewMental health apps are intriguing yet challenging tools for addressing barriers to treatment in primary care. In the current review, we seek to assist primary care professionals with evaluating and integrating mental health apps into practice. We briefly summarize two leading frameworks for evaluating mental health apps and conduct a systematic review of mental health apps across a variety of areas commonly encountered in primary care.Recent FindingsExisting frameworks can guide professionals and patients through the process of identifying apps and evaluating dimensions such as privacy and security...
Source: Current Treatment Options in Psychiatry - July 16, 2018 Category: Psychiatry Source Type: research

Death Ambivalence and Treatment Seeking: Suicidality in Opiate Addiction
AbstractPurpose of reviewRates of suicide and opiate overdose have recently skyrocketed in the USA. In light of impulsivity and impaired motivation common in people with substance use disorders, suicidality is common in addiction.Recent findingsChart review surveys indicate two primary suicidal populations that are important to distinguish for clinical practice and healthcare policy. One group is heavily composed of people with substance use disorders, in whom chronic compulsive use fosters a numbambivalence about death (low death intentionality). Many of these individuals with opiate use disorder (OUD) exaggerate suicidal...
Source: Current Treatment Options in Psychiatry - July 9, 2018 Category: Psychiatry Source Type: research

Future Directions Incorporating Novel Medications to Reduce Repeat Overdose
AbstractPurpose of reviewThe use of opioids has risen dramatically in the USA and led to an increase in opioid use disorders and deaths due to opioid-related overdoses. Current treatments for opioid use disorder are not without drawbacks, so that new treatments may be helpful in reducing opioid use. This paper reviews current pharmacologic treatments for opioid use disorder as well as emerging novel treatments that may change or improve approaches to treatment.Recent findingsThe current treatments for opioid use disorder are methadone, buprenorphine, and naltrexone. Of the three, methadone has been the most studied and lon...
Source: Current Treatment Options in Psychiatry - July 7, 2018 Category: Psychiatry Source Type: research

Financing for Collaborative Care —a Narrative Review
Opinion statementPurpose of reviewCollaborative care (CoCM) is an evidence-based model for the treatment of common mental health conditions in the primary care setting. Its workflow encourages systematic communication among clinicians outside of face-to-face patient encounters, which has posed financial challenges in traditional fee-for-service reimbursement environments.Recent findingsOrganizations have employed various financing strategies to promote CoCM sustainability, including external grants, alternate payment model contracts with specific payers, and the use of billing codes for individual components of CoCM. In re...
Source: Current Treatment Options in Psychiatry - July 6, 2018 Category: Psychiatry Source Type: research

Update on Current Treatment of Acute Opioid Overdose
AbstractPurposeOpioid use, misuse, and abuse are now a rapidly evolving epidemic in the USA. This review aims to update changes in the dosing of naloxone, describe new strategies in prehospital management, and examine in more detail the diverse pathophysiology of opioids beyond respiratory depression.Recent findingsThere are no comparative studies of old or new antidotes or procedures elucidating the superiority of one therapy. Abuse and misuse of over-the-counter loperamide and non-FDA approved tianeptine, using the herbal product kratom, and gambling with powerful fentanyl analogues are recent trends that will impact cli...
Source: Current Treatment Options in Psychiatry - July 3, 2018 Category: Psychiatry Source Type: research

Treatment Approaches for Opioid Use Disorders in Late Life
AbstractPurpose of reviewThe use of opioids and opioid-related deaths in the USA has risen to epidemic proportions. Until recently, the impact of this public health crisis in older adults has not been adequately emphasized. This paper reviews the extant literature for the management of opioid use disorder (OUD) in older adults, with a focus on both pharmacologic and non-pharmacologic interventions for OUD in older adults.Recent findingsOpioid prescriptions for older adults have dramatically increased since the 1990s. OUD in older adults is under recognized and under treated in clinical settings. Once identified, appropriat...
Source: Current Treatment Options in Psychiatry - June 1, 2018 Category: Psychiatry Source Type: research

Treatment of Late-Life Psychosis
AbstractPurpose of reviewPsychosis in late life is a cause of significant distress, suffering, and decline in the quality of life for patients, caregivers, and family members. While psychotic symptoms in later life may be related to long-standing, chronic conditions, the new onset of delusions and hallucinations often presents a diagnostic dilemma to the clinician. This paper seeks to review the overall causes and conditions related to psychosis in later life and discuss available treatment options.Recent findingsThe paucity of new research in the areas of psychosis in late-life and the near absences of clinical drug trial...
Source: Current Treatment Options in Psychiatry - June 1, 2018 Category: Psychiatry Source Type: research

Position Paper —Transference-Focused Psychotherapy (TFP) for Narcissistic Personality
AbstractPurpose of reviewThe authors describe the application of a twice-weekly, exploratory psychotherapy, Transference-Focused Psychotherapy (TFP), to patients with Narcissistic Personality Disorder (NPD). The paper describes the pathology of object relations within which narcissistic pathology can be understood, and how TFP establishes a treatment framework to address narcissistic pathology. An outline of the assessment and treatment protocol is described along with a case example to illustrate the same.Current findingsThe application of TFP to patients with NPD follows from recent research demonstrating the effectivene...
Source: Current Treatment Options in Psychiatry - June 1, 2018 Category: Psychiatry Source Type: research

Recent Developments in the Management of Insomnia in Later Life
AbstractPurpose of reviewInsomnia impacts a significant proportion of older adults yet is not an inevitable consequence of aging and is amenable to intervention. The aim of this narrative review is to provide an overview of recent recommendations and empirical findings regarding the management of insomnia in older adults.Recent findingsThe treatment of insomnia with cognitive behavioral therapy for insomnia (CBT-I) continues to be empirically supported and the recommended first-line intervention for adults. Accumulating evidence indicates that other non-pharmacological therapies for insomnia, such as mindfulness-based ther...
Source: Current Treatment Options in Psychiatry - June 1, 2018 Category: Psychiatry Source Type: research

Treatment Approaches to Sexual Dysfunction in Late Life
AbstractPurpose of reviewThis review provides an overview of the latest treatment options for sexual dysfunction in the elderly, specifically the DSM-5 male and female sexual disorders, medication-induced sexual dysfunction, and inappropriate sexual behaviors in dementia. Despite the increasing prevalence of sexual dysfunction with age, various factors including ageism, misconceptions about sexual behavior in the elderly, and discomfort discussing these issues can lead to under-recognition and under-treatment. This review highlights the importance of sexual health at any age and the available pharmacologic and non-pharmaco...
Source: Current Treatment Options in Psychiatry - June 1, 2018 Category: Psychiatry Source Type: research

The Use of Electroconvulsive Therapy in Late-Life Psychiatric Disorders
AbstractPurposeTo review the current literature regarding the use and safety of electroconvulsive therapy (ECT) in the elderly population.Recent findingsElectroconvulsive therapy (ECT) is both a safe and effective treatment for geriatric patients with severe psychiatric illness. In an era of often inadequate or poorly tolerated pharmacologic treatments, ECT can provide life-saving treatment for depression, catatonia, movement disorders, and even mood and behavioral dysregulation in dementia syndromes. The Prolonging Remission in Depressed Elderly (PRIDE) study directed by Charles Kellner has provided clear and convincing e...
Source: Current Treatment Options in Psychiatry - June 1, 2018 Category: Psychiatry Source Type: research