Current Obstetrics and Gynecology Reports This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Sentinel Lymph Node Mapping in Patients with Endometrial Carcinoma: Less Can Be More
AbstractPurpose of ReviewThe role and extent of lymphadenectomy for endometrial carcinoma has been debated for over 30  years. Many clinicians argue that there is therapeutic value for lymphadenectomy in patients deemed to be “at risk,” a designation not universally defined, despite the lack of randomized data supporting this argument. However, lymphadenectomy is associated with morbidity, including lower extre mity lymphedema. Sentinel lymph node (SLN) mapping is emerging as a viable alternative to comprehensive lymphadenectomy in the surgical staging of patients with endometrial cancer.Recent FindingsNodal disease s...
Source: Current Obstetrics and Gynecology Reports - October 2, 2016 Category: OBGYN Source Type: research

Erratum to: Caring for Pregnant Women with Opioid Use Disorder in the USA: Expanding and Improving Treatment
(Source: Current Obstetrics and Gynecology Reports)
Source: Current Obstetrics and Gynecology Reports - September 12, 2016 Category: OBGYN Source Type: research

Obstetric Hemorrhage Current Management and Usefulness of Protocols, Checklist, Drills
AbstractObstetrical hemorrhage continues to be an important contributor to maternal morbidity and mortality in the USA. Although preventable, it is still the 5th leading cause of maternal death, often due to factors associated with a delay in recognition by providers and/or delay in treatment. We cannot overlook the fact that for every maternal death due to hemorrhage, there are at least 100 women who suffer severe morbidity. It is known that implementing hemorrhage-specific protocols can improve outcomes related to this condition. This review will update readers in early detection and preparation, diagnosis, and treatment...
Source: Current Obstetrics and Gynecology Reports - September 5, 2016 Category: OBGYN Source Type: research

Making Sense Out of the Controversy: Use of SSRIs in Pregnancy
AbstractPerinatal depression complicates up to 20  % of all pregnancies. Selective serotonin reuptake inhibitor (SSRI) drugs have become the first-line treatment of depressive symptoms during pregnancy. About 7.5 % of all pregnancies are currently exposed to psychotropic medications. Recent studies suggest the SSRI medications may have some detri mental effects in pregnancy, including a possible increased risk of miscarriage, preterm delivery, clubfoot, heart defects, brain and craniofacial abnormalities, persistent pulmonary hypertension of the newborn, neonatal seizures, low neonatal Apgar score, as well as neurodevelo...
Source: Current Obstetrics and Gynecology Reports - August 7, 2016 Category: OBGYN Source Type: research

Host Immune Responses Associated with Clearance or Persistence of Human Papillomavirus Infections
AbstractSpecific types of human papillomavirus (HPV) are involved in a number of human cancers, including cervical cancer. With strict host epithelial cell tropism, HPV avoids immune detection using both passive and active mechanisms resulting in persistent, often asymptomatic infections with very limited and tightly regulated viral gene expression linked closely to the natural pathway of host epithelial cell maturation. With a focus on genital HPV infections, this review summarizes some of the host and viral factors that may influence HPV clearance, persistence, and latency and discusses factors that could favor progressi...
Source: Current Obstetrics and Gynecology Reports - July 31, 2016 Category: OBGYN Source Type: research

Epidemiology and Burden of Disease Associated with HPV Infection
< h3 class= " a-plus-plus " > Abstract < /h3 > < p class= " a-plus-plus " > Infection with certain types of human papillomavirus is associated with approximately 660,000 cancers and over 350 million cases of genital warts annually. This ubiquitous virus is transmitted by skin-to-skin contact, including through sexual contact. Of the 40 types infecting the anogenital tract, approximately 15 are considered carcinogenic, particularly types 16 and 18 which are the commonest types found in women diagnosed with invasive cervical cancer. HPV has oncogenic potential at the cervix, vagina, vulva, penis, anus, and certain head and n...
Source: Current Obstetrics and Gynecology Reports - July 26, 2016 Category: OBGYN Source Type: research

Management of Acute Postpartum Hemorrhage in Senegal
Abstract In Senegal, maternal mortality is 222.9 per 100,000 live births. Acute postpartum hemorrhage (PPH) complicates 3.1 % of all births, 44.2 % of direct causes of maternal deaths, and 33.6 % of all maternal deaths. Major causes include uterine atony, trauma, coagulation disorders, and total or partial retention of the placenta. A newer technique to address acute postpartum hemorrhage is the use of the condom balloon catheter. In Senegal, prevention means following the World Health Organization (WHO) recommendation of active management of the third stage of labor for all women in labor. This practi...
Source: Current Obstetrics and Gynecology Reports - July 17, 2016 Category: OBGYN Source Type: research

The Zika Virus and Pregnancy
Abstract Purpose of Review Following the recent association of Zika virus with microcephaly in Brazil, there has been a multitude of studies attempting to elucidate the relationship between Zika virus infection in pregnancy and congenital anomalies. The American Congress of Obstetricians and Gynecologists (ACOG), the U.S. Centers for Disease Control and Prevention (CDC), and the Society for Maternal Fetal Medicine (SMFM) have all issued guidelines governing the screening and management of pregnant patients with Zika exposure. These guidelines have rapidly evolved a...
Source: Current Obstetrics and Gynecology Reports - July 12, 2016 Category: OBGYN Source Type: research

Are We Getting Closer to Explaining Preeclampsia?
Abstract Preeclampsia continues to contribute to major maternal and neonatal morbidity and mortality worldwide. In this article, we review the pathophysiological mechanisms, screening strategies, and novel therapeutic options for preeclampsia. (Source: Current Obstetrics and Gynecology Reports)
Source: Current Obstetrics and Gynecology Reports - July 8, 2016 Category: OBGYN Source Type: research

Primary Prevention of HPV through Vaccination: Update on the Current Global Status
Abstract Ten years after the first licencing of a prophylactic human papillomavirus (HPV) vaccine, this paper reviews global information on programme coverage, as reported to WHO and from the published and grey literature. As of May 2016, 74 countries report that the HPV vaccine is on the national schedule or reimburse vaccine costs. We also summarise the latest available information on programme implementation, vaccine effectiveness, the nine-valent HPV vaccine and the accumulated safety experience with HPV vaccines. (Source: Current Obstetrics and Gynecology Reports)
Source: Current Obstetrics and Gynecology Reports - July 6, 2016 Category: OBGYN Source Type: research

Point-of-Care Thromboelastometry in the Management of Acute Obstetric Hemorrhage
Abstract Massive obstetric hemorrhage is the leading cause of maternal morbidity and direct obstetric death in developed countries. It is also the most frequent reason for maternal ICU admission. Mismanagement of maternal hemorrhage is one of the potentially preventable causes of maternal mortality in the USA. Thromboelastometry (TEM)—previously named rotational thromboelastography (ROTEG) or rotational thromboelastometry (ROTEM)—is an established viscoelastic method for hemostasis testing in whole blood. It investigates the interaction of coagulation factors, their inhibitors, anticoagulant drugs, an...
Source: Current Obstetrics and Gynecology Reports - July 4, 2016 Category: OBGYN Source Type: research

Management of Women with Field Effect of Anogenital Human Papillomavirus Infection
This article aims to review the literature, present the challenges and suggest management options for women with multifocal HPV-associated disease of the lower genital tract. (Source: Current Obstetrics and Gynecology Reports)
Source: Current Obstetrics and Gynecology Reports - July 1, 2016 Category: OBGYN Source Type: research

Recent Advances and Controversies in Peripartum Depression
Abstract Purpose of Review The purpose of this review is to update readers on recent controversies and findings on the underlying biology and clinical management of peripartum depression. Recent Findings Topics discussed include the discovery and replication of two epigenetic biomarkers of peripartum depression, two well controlled studies that do NOT find associations between in utero antidepressant exposure and cardiac defects and persistent pulmonary hypertension of the newborn and ong...
Source: Current Obstetrics and Gynecology Reports - June 30, 2016 Category: OBGYN Source Type: research

Caring for Pregnant Women with Opioid Use Disorder in the USA: Expanding and Improving Treatment
Abstract Purpose of the Review Opioid use disorder in the USA is rising at an alarming rate, particularly among women of childbearing age. Pregnant women with opioid use disorder face numerous barriers to care, including limited access to treatment, stigma, and fear of legal consequences. This review of opioid use disorder in pregnancy is designed to assist health care providers caring for pregnant and postpartum women with the goal of expanding evidence-based treatment practices for this vulnerable population. ...
Source: Current Obstetrics and Gynecology Reports - June 30, 2016 Category: OBGYN Source Type: research

Vulvar Cancer, HPV Infection, and HIV Status
Abstract Vulvar cancer is rare, but its incidence is increasing particularly in young women. This increase has been attributed to increasing human papillomavirus (HPV) infection with high-risk types of HPV. There is an association between HPV and vulvar cancer, but the pathophysiology of this relationship is not fully understood, nor is the complexity of HPV/HIV co-infection and its association with vulvar cancer. Even with the limited literature, there is real evidence on the interrelationship between HPV, vulvar cancer in HIV-positive women, and that in the setting of HIV infection, careful examination ...
Source: Current Obstetrics and Gynecology Reports - June 30, 2016 Category: OBGYN Source Type: research