Intrapartum Management of Maternal Congenital Heart Disease
AbstractPurpose of ReviewThis review discusses the special considerations in the care of pregnant patients with congenital heart disease (CHD) to minimize obstetric risks and avoid cardiac complications.Recent FindingsMultidisciplinary team planning is a cornerstone in the care of patients with CHD in pregnancy. Most patients with CHD should have neuraxial anesthesia and laboratory monitoring during labor and delivery, but the need for pulse oximetry, telemetry, and invasive hemodynamic monitoring should be individualized based on patient risk. Additionally, most patients with CHD can safely have a vaginal delivery at 39 â...
Source: Current Obstetrics and Gynecology Reports - September 8, 2023 Category: OBGYN Source Type: research

Intrapartum Management of Moderate to Severe COVID-19: an Evidence-Based Update
AbstractPurpose of ReviewThis review was performed to provide an evidence-based approach to specific intrapartum management considerations for pregnant patients with moderate or severe COVID-19.Recent FindingsPregnant patients are at increased risk for serious illness related to COVID-19 infection including respiratory failure. Timing, mode, and location of delivery may be impacted by severe COVID-19 infection. The majority of medical therapies and other interventions are not contraindicated in the setting of COVID-19 infection and pregnancy.SummaryIntrapartum management of pregnant women with moderate or severe COVID-19 i...
Source: Current Obstetrics and Gynecology Reports - August 28, 2023 Category: OBGYN Source Type: research

Uterine Artery Embolization for Adenomyosis: A Review of Imaging, Techniques, Complications and Outcomes
AbstractPurpose of ReviewThis review aims to provide a comprehensive summary of the literature regarding the use of uterine artery embolization (UAE) in the treatment of pure adenomyosis and to document indications, results and complications for symptomatic patients who have failed conservative treatment and wish to avoid hysterectomy.Recent FindingsThere is growing evidence to support UAE as a safe and successful treatment for the treatment of symptomatic pure adenomyosis.SummaryPure adenomyosis has historically been treated with conservative pharmacological treatments including non-steroidal anti-inflammatories, hormonal...
Source: Current Obstetrics and Gynecology Reports - August 14, 2023 Category: OBGYN Source Type: research

Enabling Breastfeeding for Women with Obesity
AbstractPurpose of ReviewThis narrative review summarizes the epidemiology of breastfeeding outcomes by BMI category, describes research that elucidates underlying mechanisms, critically appraises intervention studies aimed at improving breastfeeding outcomes for lactating parents with obesity, and provides clinical management considerations.Recent FindingsExclusive breastfeeding for the first 6  months, with continued breastfeeding for at least 1 to 2 years, is strongly endorsed by many public health and professional organizations. Over 80% of parents in the USA initiate breastfeeding. While breastfeeding initiation rat...
Source: Current Obstetrics and Gynecology Reports - June 8, 2023 Category: OBGYN Source Type: research

Adenomyosis: Transvaginal Ultrasound and Imaging Innovations for Diagnosis
AbstractPurpose of ReviewThere have been considerable advances in recent years using transvaginal sonography (TVUS) to diagnose adenomyosis. The diagnosis, however, is highly dependent upon the recognition of specific sonographic features as defined by the Morphological Uterus Sonographic Assessment (MUSA) statement. The main goal of this article is to review the literature in the last 5  years on specific TVUS features and imaging innovations for its diagnosis. We also sought to identify studies that evaluated the association between imaging-diagnosed adenomyosis and other clinical conditions.Recent FindingsDirect and in...
Source: Current Obstetrics and Gynecology Reports - June 6, 2023 Category: OBGYN Source Type: research

Antenatal Optimization of Maternal Anemia Leads to Decreased Risks of Maternal Morbidity
AbstractPurpose of ReviewOur review focuses on the appropriate use of intravenous iron to increase the likelihood of achieving target hemoglobin levels prior to delivery to reduce maternal morbidity.Recent FindingsIron deficiency anemia (IDA) is a leading contributor to severe maternal morbidity and mortality. Prenatal treatment of IDA has been demonstrated to reduce the likelihood of adverse maternal outcomes. Recent investigations of intravenous iron supplementation have demonstrated superior efficacy and high tolerability for the treatment of IDA in the third trimester, compared against oral regimens. However, it is unk...
Source: Current Obstetrics and Gynecology Reports - June 3, 2023 Category: OBGYN Source Type: research

Updates on Anti-seizure Medication Use in Pregnancy
AbstractPurpose of ReviewCare of people with epilepsy and gestational capacity throughout pregnancy involves weighing risks of seizures with the known risks of anti-seizure medications, and requires planning and patient counseling.Recent FindingsAnti-seizure medications are associated with increased risk of congenital malformations. Further study is needed to understand the risk profile of newer anti-seizure medications in pregnancy. Cognitive outcomes of infants exposed to anti-seizure medications in utero vary, but valproate is associated with an increased risk of cognitive teratogenesis. Topiramate may also have an adve...
Source: Current Obstetrics and Gynecology Reports - June 3, 2023 Category: OBGYN Source Type: research

An Update on Contraception for Transgender, Non-binary, and Gender-expansive Individuals
AbstractPurpose of ReviewThe goal of this review is to summarize the current understanding of how exogenous testosterone and estrogen affects fertility in transgender, non-binary, and gender-expansive (TGE) individuals, and what contraceptive options are available for this population.Recent FindingsRecent studies have shown conflicting findings with regards to the effects of exogenous testosterone on ovulation and the endometrium; however, the overarching conclusion continues to be that it cannot be viewed as a contraceptive. Survey studies conducted in the past 5  years have repeatedly shown disparities in the rates of c...
Source: Current Obstetrics and Gynecology Reports - May 19, 2023 Category: OBGYN Source Type: research

Intrapartum Oxygen for Fetal Resuscitation: State of the Science
AbstractPurpose of ReviewThis review aims to summarize the current evidence regarding maternal oxygen supplementation for Category II fetal heart tracings (FHT) in labor. We aim to evaluate the theoretical rationale for oxygen administration, the clinical efficacy of supplemental oxygen, and the potential risks.Recent FindingsMaternal oxygen supplementation is an intrauterine resuscitation technique rooted in the theoretic rationale that hyperoxygenating the mother results in increased oxygen transfer to the fetus. However, recent data suggest otherwise. Randomized controlled trials on the efficacy of oxygen supplementatio...
Source: Current Obstetrics and Gynecology Reports - May 18, 2023 Category: OBGYN Source Type: research

Second Trimester Medication Abortion Regimens and the Mifepristone-Misoprostol Dosing Interval
AbstractPurpose of ReviewThe purpose of this article is to review current methods of induction termination of pregnancy in the second trimester. The specific area of focus is recent publication regarding timing of mifepristone and misoprostol dosing. Current international guidelines recommend initial treatment with mifepristone followed by misoprostol after 24 to 48  h.Recent FindingsRetrospective studies indicate that a shorter interval between mifepristone and misoprostol of less than 12  h or even concomitant administration may result in a shorter total abortion time without increasing risk of incomplete abortion or c...
Source: Current Obstetrics and Gynecology Reports - May 6, 2023 Category: OBGYN Source Type: research

Intrauterine Device Complications and Their Management
AbstractPurpose of ReviewIndividuals are using intrauterine devices (IUDs) increasingly more frequently not only for contraception and emergency contraception, but also, in the case of hormonal IUDs, for the management of heavy menstrual bleeding and endometrial hyperplasia. While IUD complications are rare, their increasing prevalence is inevitably linked to more patients requiring specialized care for these complications. This review summarizes the most common complications, inclusive of perforation, expulsion, concurrent pregnancy, and difficult IUD removal, as well as their management strategies.Recent FindingsThe two ...
Source: Current Obstetrics and Gynecology Reports - April 27, 2023 Category: OBGYN Source Type: research

Management of Labor and Delivery to Reduce Risk for Cesarean Birth in Women with Obesity
AbstractPurpose of reviewThis review provides readers with current management guidelines for labor and birth for individuals with obesity and includes a summary of methods for lowering the risk for cesarean birth. The goal of this review was to examine the evidence for women with obesity having uncomplicated labor courses and to apply the concept of metabolically healthy obesity to cesarean birth reduction.Recent findingsOne-fifth to one-third of those in labor will have a pregnancy complicated by obesity. A variety of adipokines produced in excess adipose tissue counteract the normal physiology of labor and increase syste...
Source: Current Obstetrics and Gynecology Reports - April 17, 2023 Category: OBGYN Source Type: research

Infertility Treatment in Women with Obesity
This article examines the interplay of obesity with fertility treatment and reviews the most recent evidence on how weight loss treatments impact reproductive outcomes.Recent FindingsAlthough weight loss can improve ovulatory dysfunction, the sum of evidence does not show improved birth rates or ART outcomes. For those with PCOS and obesity, bariatric surgery may play a role in improving both natural conception rates and ART outcomes. Physical activity has also been shown to improve ART outcomes regardless of BMI or weight loss achievement.SummaryWeight loss may be useful in improving fecundity though recent research sugge...
Source: Current Obstetrics and Gynecology Reports - April 14, 2023 Category: OBGYN Source Type: research

Preventing Adverse Cardiovascular Outcomes in Pregnancy Complicated by Obesity
AbstractPurpose of ReviewObesity is a chronic disease that is becoming increasingly prevalent, and more individuals of reproductive age have obesity prior to becoming pregnant. Obesity in pregnancy is associated with short- and long-term adverse consequences for both the birthing person and their offspring which have been associated with increased long-term cardiovascular morbidity and mortality. The goal of this review is to discuss what is currently understood about the relationship between maternal obesity and adverse pregnancy outcomes (APOs), the association between APOs and future cardiovascular disease (CVD) risk, a...
Source: Current Obstetrics and Gynecology Reports - April 6, 2023 Category: OBGYN Source Type: research

Congenital Anomalies in Women with Obesity
AbstractPurpose of ReviewIn addition to a general overview of congenital anomalies in pregnant people with obesity as well as new data on the topic, this review aims to discuss the challenges in antenatal diagnosis of anomalies via sonogram.Recent FindingsObesity is associated with a dose-dependent increase in risk of certain congenital anomalies including cardiac malformations. The risk reduction of neural tube defects with folic acid supplementation is not as significant in offspring of patients with obesity compared to their normal weight counterparts. The addition of an early anatomy scan at 13 to15 weeks in addition t...
Source: Current Obstetrics and Gynecology Reports - March 21, 2023 Category: OBGYN Source Type: research