Application of nanotags and nanobodies for live cell single-molecule imaging of the Z-ring in Escherichia coli
Curr Genet. 2023 Apr 6. doi: 10.1007/s00294-023-01266-2. Online ahead of print.ABSTRACTUnderstanding where proteins are localized in a bacterial cell is essential for understanding their function and regulation. This is particularly important for proteins that are involved in cell division, which localize at the division septum and assemble into highly regulated complexes. Current knowledge of these complexes has been greatly facilitated by super-resolution imaging using fluorescent protein fusions. Herein, we demonstrate with FtsZ that single-molecule PALM images can be obtained in-vivo using a genetically fused nanotag (...
Source: Current Genetics - April 6, 2023 Category: Genetics & Stem Cells Authors: Emma Westlund Axel Bergenstr åle Alaska Pokhrel Helena Chan Ulf Skoglund Daniel O Daley Bill S öderström Source Type: research

Diverse and dynamic forms of gene regulation by the S. cerevisiae histone methyltransferase Set1
We describe the COMPASS complex, factors that influence H3K4 methylation, and the roles of Set1 in gene silencing at telomeres and heterochromatin, as well as repression and activation at euchromatic loci. We also discuss proteins that "read" H3K4 methyl marks to regulate transcription and summarize alternate functions for Set1 beyond H3K4 methylation.PMID:37000206 | DOI:10.1007/s00294-023-01265-3 (Source: Current Genetics)
Source: Current Genetics - March 31, 2023 Category: Genetics & Stem Cells Authors: Neha Deshpande Mary Bryk Source Type: research

Diverse and dynamic forms of gene regulation by the S. cerevisiae histone methyltransferase Set1
We describe the COMPASS complex, factors that influence H3K4 methylation, and the roles of Set1 in gene silencing at telomeres and heterochromatin, as well as repression and activation at euchromatic loci. We also discuss proteins that "read" H3K4 methyl marks to regulate transcription and summarize alternate functions for Set1 beyond H3K4 methylation.PMID:37000206 | DOI:10.1007/s00294-023-01265-3 (Source: Current Genetics)
Source: Current Genetics - March 31, 2023 Category: Genetics & Stem Cells Authors: Neha Deshpande Mary Bryk Source Type: research

Diverse and dynamic forms of gene regulation by the S. cerevisiae histone methyltransferase Set1
We describe the COMPASS complex, factors that influence H3K4 methylation, and the roles of Set1 in gene silencing at telomeres and heterochromatin, as well as repression and activation at euchromatic loci. We also discuss proteins that "read" H3K4 methyl marks to regulate transcription and summarize alternate functions for Set1 beyond H3K4 methylation.PMID:37000206 | DOI:10.1007/s00294-023-01265-3 (Source: Current Genetics)
Source: Current Genetics - March 31, 2023 Category: Genetics & Stem Cells Authors: Neha Deshpande Mary Bryk Source Type: research

Diverse and dynamic forms of gene regulation by the S. cerevisiae histone methyltransferase Set1
We describe the COMPASS complex, factors that influence H3K4 methylation, and the roles of Set1 in gene silencing at telomeres and heterochromatin, as well as repression and activation at euchromatic loci. We also discuss proteins that "read" H3K4 methyl marks to regulate transcription and summarize alternate functions for Set1 beyond H3K4 methylation.PMID:37000206 | DOI:10.1007/s00294-023-01265-3 (Source: Current Genetics)
Source: Current Genetics - March 31, 2023 Category: Genetics & Stem Cells Authors: Neha Deshpande Mary Bryk Source Type: research

Diverse and dynamic forms of gene regulation by the S. cerevisiae histone methyltransferase Set1
We describe the COMPASS complex, factors that influence H3K4 methylation, and the roles of Set1 in gene silencing at telomeres and heterochromatin, as well as repression and activation at euchromatic loci. We also discuss proteins that "read" H3K4 methyl marks to regulate transcription and summarize alternate functions for Set1 beyond H3K4 methylation.PMID:37000206 | DOI:10.1007/s00294-023-01265-3 (Source: Current Genetics)
Source: Current Genetics - March 31, 2023 Category: Genetics & Stem Cells Authors: Neha Deshpande Mary Bryk Source Type: research

Morphogenic plasticity: the pathogenic attribute of Candida albicans
Curr Genet. 2023 Mar 22. doi: 10.1007/s00294-023-01263-5. Online ahead of print.ABSTRACTCandida albicans is a commensal organism of the human gastrointestinal tract and a prevalent opportunistic pathogen. It exhibits different morphogenic forms to survive in different host niches with distinct environmental conditions (pH, temperature, oxidative stress, nutrients, serum, chemicals, radiation, etc.) and genetic factors (transcription factors and genes). The different morphogenic forms of C. albicans are yeast, hyphal, pseudohyphal, white, opaque, and transient gray cells, planktonic and biofilm forms of cells. These forms d...
Source: Current Genetics - March 22, 2023 Category: Genetics & Stem Cells Authors: Priya Prasad Meena Tippana Source Type: research

Morphogenic plasticity: the pathogenic attribute of Candida albicans
Curr Genet. 2023 Mar 22. doi: 10.1007/s00294-023-01263-5. Online ahead of print.ABSTRACTCandida albicans is a commensal organism of the human gastrointestinal tract and a prevalent opportunistic pathogen. It exhibits different morphogenic forms to survive in different host niches with distinct environmental conditions (pH, temperature, oxidative stress, nutrients, serum, chemicals, radiation, etc.) and genetic factors (transcription factors and genes). The different morphogenic forms of C. albicans are yeast, hyphal, pseudohyphal, white, opaque, and transient gray cells, planktonic and biofilm forms of cells. These forms d...
Source: Current Genetics - March 22, 2023 Category: Genetics & Stem Cells Authors: Priya Prasad Meena Tippana Source Type: research

Morphogenic plasticity: the pathogenic attribute of Candida albicans
Curr Genet. 2023 Mar 22. doi: 10.1007/s00294-023-01263-5. Online ahead of print.ABSTRACTCandida albicans is a commensal organism of the human gastrointestinal tract and a prevalent opportunistic pathogen. It exhibits different morphogenic forms to survive in different host niches with distinct environmental conditions (pH, temperature, oxidative stress, nutrients, serum, chemicals, radiation, etc.) and genetic factors (transcription factors and genes). The different morphogenic forms of C. albicans are yeast, hyphal, pseudohyphal, white, opaque, and transient gray cells, planktonic and biofilm forms of cells. These forms d...
Source: Current Genetics - March 22, 2023 Category: Genetics & Stem Cells Authors: Priya Prasad Meena Tippana Source Type: research

Morphogenic plasticity: the pathogenic attribute of Candida albicans
Curr Genet. 2023 Mar 22. doi: 10.1007/s00294-023-01263-5. Online ahead of print.ABSTRACTCandida albicans is a commensal organism of the human gastrointestinal tract and a prevalent opportunistic pathogen. It exhibits different morphogenic forms to survive in different host niches with distinct environmental conditions (pH, temperature, oxidative stress, nutrients, serum, chemicals, radiation, etc.) and genetic factors (transcription factors and genes). The different morphogenic forms of C. albicans are yeast, hyphal, pseudohyphal, white, opaque, and transient gray cells, planktonic and biofilm forms of cells. These forms d...
Source: Current Genetics - March 22, 2023 Category: Genetics & Stem Cells Authors: Priya Prasad Meena Tippana Source Type: research

Morphogenic plasticity: the pathogenic attribute of Candida albicans
Curr Genet. 2023 Mar 22. doi: 10.1007/s00294-023-01263-5. Online ahead of print.ABSTRACTCandida albicans is a commensal organism of the human gastrointestinal tract and a prevalent opportunistic pathogen. It exhibits different morphogenic forms to survive in different host niches with distinct environmental conditions (pH, temperature, oxidative stress, nutrients, serum, chemicals, radiation, etc.) and genetic factors (transcription factors and genes). The different morphogenic forms of C. albicans are yeast, hyphal, pseudohyphal, white, opaque, and transient gray cells, planktonic and biofilm forms of cells. These forms d...
Source: Current Genetics - March 22, 2023 Category: Genetics & Stem Cells Authors: Priya Prasad Meena Tippana Source Type: research

Morphogenic plasticity: the pathogenic attribute of Candida albicans
Curr Genet. 2023 Mar 22. doi: 10.1007/s00294-023-01263-5. Online ahead of print.ABSTRACTCandida albicans is a commensal organism of the human gastrointestinal tract and a prevalent opportunistic pathogen. It exhibits different morphogenic forms to survive in different host niches with distinct environmental conditions (pH, temperature, oxidative stress, nutrients, serum, chemicals, radiation, etc.) and genetic factors (transcription factors and genes). The different morphogenic forms of C. albicans are yeast, hyphal, pseudohyphal, white, opaque, and transient gray cells, planktonic and biofilm forms of cells. These forms d...
Source: Current Genetics - March 22, 2023 Category: Genetics & Stem Cells Authors: Priya Prasad Meena Tippana Source Type: research

Morphogenic plasticity: the pathogenic attribute of Candida albicans
Curr Genet. 2023 Mar 22. doi: 10.1007/s00294-023-01263-5. Online ahead of print.ABSTRACTCandida albicans is a commensal organism of the human gastrointestinal tract and a prevalent opportunistic pathogen. It exhibits different morphogenic forms to survive in different host niches with distinct environmental conditions (pH, temperature, oxidative stress, nutrients, serum, chemicals, radiation, etc.) and genetic factors (transcription factors and genes). The different morphogenic forms of C. albicans are yeast, hyphal, pseudohyphal, white, opaque, and transient gray cells, planktonic and biofilm forms of cells. These forms d...
Source: Current Genetics - March 22, 2023 Category: Genetics & Stem Cells Authors: Priya Prasad Meena Tippana Source Type: research

Genomic analyses of drug-resistant Salmonella enterica serovar Heidelberg strains isolated from meat and related sources between 2013 and 2017 in the south region of Brazil
In conclusion, the presence of multidrug-resistant S. Heidelberg strains in Brazil showing a global genomic relationship may alert for the necessity of stronger surveillance measures by food safety and public health authorities to limit its spread to humans and animals through foods.PMID:36920496 | DOI:10.1007/s00294-023-01264-4 (Source: Current Genetics)
Source: Current Genetics - March 15, 2023 Category: Genetics & Stem Cells Authors: Felipe Pinheiro Vilela D ália Dos Prazeres Rodrigues Marc William Allard Juliana Pfrimer Falc ão Source Type: research

Genomic analyses of drug-resistant Salmonella enterica serovar Heidelberg strains isolated from meat and related sources between 2013 and 2017 in the south region of Brazil
In conclusion, the presence of multidrug-resistant S. Heidelberg strains in Brazil showing a global genomic relationship may alert for the necessity of stronger surveillance measures by food safety and public health authorities to limit its spread to humans and animals through foods.PMID:36920496 | DOI:10.1007/s00294-023-01264-4 (Source: Current Genetics)
Source: Current Genetics - March 15, 2023 Category: Genetics & Stem Cells Authors: Felipe Pinheiro Vilela D ália Dos Prazeres Rodrigues Marc William Allard Juliana Pfrimer Falc ão Source Type: research