TOF1 and RRM3 reveal a link between gene silencing and the pausing of replication forks
Curr Genet. 2023 Jun 22. doi: 10.1007/s00294-023-01273-3. Online ahead of print.ABSTRACTEukaryotic DNA replication is accompanied by the disassembly and reassembly of nucleosomes and the transmission of epigenetic marks to the newly assembled chromatids. Several histone chaperones, including CAF-1 and Asf1p, are central to these processes. On the other hand, replication forks pause at numerous positions throughout the genome, but it is not known if and how this pausing affects the reassembly and maintenance of chromatin structures. Here, we applied drug-free gene silencing assays to analyze the genetic interactions between...
Source: Current Genetics - June 22, 2023 Category: Genetics & Stem Cells Authors: Kholoud Shaban Andrew Dolson Ashley Fisher Emma Lessard Safia Mahabub Sauty Krassimir Yankulov Source Type: research
TOF1 and RRM3 reveal a link between gene silencing and the pausing of replication forks
Curr Genet. 2023 Jun 22. doi: 10.1007/s00294-023-01273-3. Online ahead of print.ABSTRACTEukaryotic DNA replication is accompanied by the disassembly and reassembly of nucleosomes and the transmission of epigenetic marks to the newly assembled chromatids. Several histone chaperones, including CAF-1 and Asf1p, are central to these processes. On the other hand, replication forks pause at numerous positions throughout the genome, but it is not known if and how this pausing affects the reassembly and maintenance of chromatin structures. Here, we applied drug-free gene silencing assays to analyze the genetic interactions between...
Source: Current Genetics - June 22, 2023 Category: Genetics & Stem Cells Authors: Kholoud Shaban Andrew Dolson Ashley Fisher Emma Lessard Safia Mahabub Sauty Krassimir Yankulov Source Type: research
TOF1 and RRM3 reveal a link between gene silencing and the pausing of replication forks
Curr Genet. 2023 Jun 22. doi: 10.1007/s00294-023-01273-3. Online ahead of print.ABSTRACTEukaryotic DNA replication is accompanied by the disassembly and reassembly of nucleosomes and the transmission of epigenetic marks to the newly assembled chromatids. Several histone chaperones, including CAF-1 and Asf1p, are central to these processes. On the other hand, replication forks pause at numerous positions throughout the genome, but it is not known if and how this pausing affects the reassembly and maintenance of chromatin structures. Here, we applied drug-free gene silencing assays to analyze the genetic interactions between...
Source: Current Genetics - June 22, 2023 Category: Genetics & Stem Cells Authors: Kholoud Shaban Andrew Dolson Ashley Fisher Emma Lessard Safia Mahabub Sauty Krassimir Yankulov Source Type: research
TOF1 and RRM3 reveal a link between gene silencing and the pausing of replication forks
Curr Genet. 2023 Jun 22. doi: 10.1007/s00294-023-01273-3. Online ahead of print.ABSTRACTEukaryotic DNA replication is accompanied by the disassembly and reassembly of nucleosomes and the transmission of epigenetic marks to the newly assembled chromatids. Several histone chaperones, including CAF-1 and Asf1p, are central to these processes. On the other hand, replication forks pause at numerous positions throughout the genome, but it is not known if and how this pausing affects the reassembly and maintenance of chromatin structures. Here, we applied drug-free gene silencing assays to analyze the genetic interactions between...
Source: Current Genetics - June 22, 2023 Category: Genetics & Stem Cells Authors: Kholoud Shaban Andrew Dolson Ashley Fisher Emma Lessard Safia Mahabub Sauty Krassimir Yankulov Source Type: research
TOF1 and RRM3 reveal a link between gene silencing and the pausing of replication forks
Curr Genet. 2023 Jun 22. doi: 10.1007/s00294-023-01273-3. Online ahead of print.ABSTRACTEukaryotic DNA replication is accompanied by the disassembly and reassembly of nucleosomes and the transmission of epigenetic marks to the newly assembled chromatids. Several histone chaperones, including CAF-1 and Asf1p, are central to these processes. On the other hand, replication forks pause at numerous positions throughout the genome, but it is not known if and how this pausing affects the reassembly and maintenance of chromatin structures. Here, we applied drug-free gene silencing assays to analyze the genetic interactions between...
Source: Current Genetics - June 22, 2023 Category: Genetics & Stem Cells Authors: Kholoud Shaban Andrew Dolson Ashley Fisher Emma Lessard Safia Mahabub Sauty Krassimir Yankulov Source Type: research
TOF1 and RRM3 reveal a link between gene silencing and the pausing of replication forks
Curr Genet. 2023 Jun 22. doi: 10.1007/s00294-023-01273-3. Online ahead of print.ABSTRACTEukaryotic DNA replication is accompanied by the disassembly and reassembly of nucleosomes and the transmission of epigenetic marks to the newly assembled chromatids. Several histone chaperones, including CAF-1 and Asf1p, are central to these processes. On the other hand, replication forks pause at numerous positions throughout the genome, but it is not known if and how this pausing affects the reassembly and maintenance of chromatin structures. Here, we applied drug-free gene silencing assays to analyze the genetic interactions between...
Source: Current Genetics - June 22, 2023 Category: Genetics & Stem Cells Authors: Kholoud Shaban Andrew Dolson Ashley Fisher Emma Lessard Safia Mahabub Sauty Krassimir Yankulov Source Type: research
TOF1 and RRM3 reveal a link between gene silencing and the pausing of replication forks
Curr Genet. 2023 Jun 22. doi: 10.1007/s00294-023-01273-3. Online ahead of print.ABSTRACTEukaryotic DNA replication is accompanied by the disassembly and reassembly of nucleosomes and the transmission of epigenetic marks to the newly assembled chromatids. Several histone chaperones, including CAF-1 and Asf1p, are central to these processes. On the other hand, replication forks pause at numerous positions throughout the genome, but it is not known if and how this pausing affects the reassembly and maintenance of chromatin structures. Here, we applied drug-free gene silencing assays to analyze the genetic interactions between...
Source: Current Genetics - June 22, 2023 Category: Genetics & Stem Cells Authors: Kholoud Shaban Andrew Dolson Ashley Fisher Emma Lessard Safia Mahabub Sauty Krassimir Yankulov Source Type: research
TOF1 and RRM3 reveal a link between gene silencing and the pausing of replication forks
Curr Genet. 2023 Jun 22. doi: 10.1007/s00294-023-01273-3. Online ahead of print.ABSTRACTEukaryotic DNA replication is accompanied by the disassembly and reassembly of nucleosomes and the transmission of epigenetic marks to the newly assembled chromatids. Several histone chaperones, including CAF-1 and Asf1p, are central to these processes. On the other hand, replication forks pause at numerous positions throughout the genome, but it is not known if and how this pausing affects the reassembly and maintenance of chromatin structures. Here, we applied drug-free gene silencing assays to analyze the genetic interactions between...
Source: Current Genetics - June 22, 2023 Category: Genetics & Stem Cells Authors: Kholoud Shaban Andrew Dolson Ashley Fisher Emma Lessard Safia Mahabub Sauty Krassimir Yankulov Source Type: research
TOF1 and RRM3 reveal a link between gene silencing and the pausing of replication forks
Curr Genet. 2023 Jun 22. doi: 10.1007/s00294-023-01273-3. Online ahead of print.ABSTRACTEukaryotic DNA replication is accompanied by the disassembly and reassembly of nucleosomes and the transmission of epigenetic marks to the newly assembled chromatids. Several histone chaperones, including CAF-1 and Asf1p, are central to these processes. On the other hand, replication forks pause at numerous positions throughout the genome, but it is not known if and how this pausing affects the reassembly and maintenance of chromatin structures. Here, we applied drug-free gene silencing assays to analyze the genetic interactions between...
Source: Current Genetics - June 22, 2023 Category: Genetics & Stem Cells Authors: Kholoud Shaban Andrew Dolson Ashley Fisher Emma Lessard Safia Mahabub Sauty Krassimir Yankulov Source Type: research
TOF1 and RRM3 reveal a link between gene silencing and the pausing of replication forks
Curr Genet. 2023 Jun 22. doi: 10.1007/s00294-023-01273-3. Online ahead of print.ABSTRACTEukaryotic DNA replication is accompanied by the disassembly and reassembly of nucleosomes and the transmission of epigenetic marks to the newly assembled chromatids. Several histone chaperones, including CAF-1 and Asf1p, are central to these processes. On the other hand, replication forks pause at numerous positions throughout the genome, but it is not known if and how this pausing affects the reassembly and maintenance of chromatin structures. Here, we applied drug-free gene silencing assays to analyze the genetic interactions between...
Source: Current Genetics - June 22, 2023 Category: Genetics & Stem Cells Authors: Kholoud Shaban Andrew Dolson Ashley Fisher Emma Lessard Safia Mahabub Sauty Krassimir Yankulov Source Type: research
TOF1 and RRM3 reveal a link between gene silencing and the pausing of replication forks
Curr Genet. 2023 Jun 22. doi: 10.1007/s00294-023-01273-3. Online ahead of print.ABSTRACTEukaryotic DNA replication is accompanied by the disassembly and reassembly of nucleosomes and the transmission of epigenetic marks to the newly assembled chromatids. Several histone chaperones, including CAF-1 and Asf1p, are central to these processes. On the other hand, replication forks pause at numerous positions throughout the genome, but it is not known if and how this pausing affects the reassembly and maintenance of chromatin structures. Here, we applied drug-free gene silencing assays to analyze the genetic interactions between...
Source: Current Genetics - June 22, 2023 Category: Genetics & Stem Cells Authors: Kholoud Shaban Andrew Dolson Ashley Fisher Emma Lessard Safia Mahabub Sauty Krassimir Yankulov Source Type: research
TOF1 and RRM3 reveal a link between gene silencing and the pausing of replication forks
Curr Genet. 2023 Jun 22. doi: 10.1007/s00294-023-01273-3. Online ahead of print.ABSTRACTEukaryotic DNA replication is accompanied by the disassembly and reassembly of nucleosomes and the transmission of epigenetic marks to the newly assembled chromatids. Several histone chaperones, including CAF-1 and Asf1p, are central to these processes. On the other hand, replication forks pause at numerous positions throughout the genome, but it is not known if and how this pausing affects the reassembly and maintenance of chromatin structures. Here, we applied drug-free gene silencing assays to analyze the genetic interactions between...
Source: Current Genetics - June 22, 2023 Category: Genetics & Stem Cells Authors: Kholoud Shaban Andrew Dolson Ashley Fisher Emma Lessard Safia Mahabub Sauty Krassimir Yankulov Source Type: research
TOF1 and RRM3 reveal a link between gene silencing and the pausing of replication forks
Curr Genet. 2023 Jun 22. doi: 10.1007/s00294-023-01273-3. Online ahead of print.ABSTRACTEukaryotic DNA replication is accompanied by the disassembly and reassembly of nucleosomes and the transmission of epigenetic marks to the newly assembled chromatids. Several histone chaperones, including CAF-1 and Asf1p, are central to these processes. On the other hand, replication forks pause at numerous positions throughout the genome, but it is not known if and how this pausing affects the reassembly and maintenance of chromatin structures. Here, we applied drug-free gene silencing assays to analyze the genetic interactions between...
Source: Current Genetics - June 22, 2023 Category: Genetics & Stem Cells Authors: Kholoud Shaban Andrew Dolson Ashley Fisher Emma Lessard Safia Mahabub Sauty Krassimir Yankulov Source Type: research
TOF1 and RRM3 reveal a link between gene silencing and the pausing of replication forks
Curr Genet. 2023 Jun 22. doi: 10.1007/s00294-023-01273-3. Online ahead of print.ABSTRACTEukaryotic DNA replication is accompanied by the disassembly and reassembly of nucleosomes and the transmission of epigenetic marks to the newly assembled chromatids. Several histone chaperones, including CAF-1 and Asf1p, are central to these processes. On the other hand, replication forks pause at numerous positions throughout the genome, but it is not known if and how this pausing affects the reassembly and maintenance of chromatin structures. Here, we applied drug-free gene silencing assays to analyze the genetic interactions between...
Source: Current Genetics - June 22, 2023 Category: Genetics & Stem Cells Authors: Kholoud Shaban Andrew Dolson Ashley Fisher Emma Lessard Safia Mahabub Sauty Krassimir Yankulov Source Type: research
TOF1 and RRM3 reveal a link between gene silencing and the pausing of replication forks
Curr Genet. 2023 Jun 22. doi: 10.1007/s00294-023-01273-3. Online ahead of print.ABSTRACTEukaryotic DNA replication is accompanied by the disassembly and reassembly of nucleosomes and the transmission of epigenetic marks to the newly assembled chromatids. Several histone chaperones, including CAF-1 and Asf1p, are central to these processes. On the other hand, replication forks pause at numerous positions throughout the genome, but it is not known if and how this pausing affects the reassembly and maintenance of chromatin structures. Here, we applied drug-free gene silencing assays to analyze the genetic interactions between...
Source: Current Genetics - June 22, 2023 Category: Genetics & Stem Cells Authors: Kholoud Shaban Andrew Dolson Ashley Fisher Emma Lessard Safia Mahabub Sauty Krassimir Yankulov Source Type: research
