TOF1 and RRM3 reveal a link between gene silencing and the pausing of replication forks
Curr Genet. 2023 Jun 22. doi: 10.1007/s00294-023-01273-3. Online ahead of print.ABSTRACTEukaryotic DNA replication is accompanied by the disassembly and reassembly of nucleosomes and the transmission of epigenetic marks to the newly assembled chromatids. Several histone chaperones, including CAF-1 and Asf1p, are central to these processes. On the other hand, replication forks pause at numerous positions throughout the genome, but it is not known if and how this pausing affects the reassembly and maintenance of chromatin structures. Here, we applied drug-free gene silencing assays to analyze the genetic interactions between...
Source: Current Genetics - June 22, 2023 Category: Genetics & Stem Cells Authors: Kholoud Shaban Andrew Dolson Ashley Fisher Emma Lessard Safia Mahabub Sauty Krassimir Yankulov Source Type: research
TOF1 and RRM3 reveal a link between gene silencing and the pausing of replication forks
Curr Genet. 2023 Jun 22. doi: 10.1007/s00294-023-01273-3. Online ahead of print.ABSTRACTEukaryotic DNA replication is accompanied by the disassembly and reassembly of nucleosomes and the transmission of epigenetic marks to the newly assembled chromatids. Several histone chaperones, including CAF-1 and Asf1p, are central to these processes. On the other hand, replication forks pause at numerous positions throughout the genome, but it is not known if and how this pausing affects the reassembly and maintenance of chromatin structures. Here, we applied drug-free gene silencing assays to analyze the genetic interactions between...
Source: Current Genetics - June 22, 2023 Category: Genetics & Stem Cells Authors: Kholoud Shaban Andrew Dolson Ashley Fisher Emma Lessard Safia Mahabub Sauty Krassimir Yankulov Source Type: research
TOF1 and RRM3 reveal a link between gene silencing and the pausing of replication forks
Curr Genet. 2023 Jun 22. doi: 10.1007/s00294-023-01273-3. Online ahead of print.ABSTRACTEukaryotic DNA replication is accompanied by the disassembly and reassembly of nucleosomes and the transmission of epigenetic marks to the newly assembled chromatids. Several histone chaperones, including CAF-1 and Asf1p, are central to these processes. On the other hand, replication forks pause at numerous positions throughout the genome, but it is not known if and how this pausing affects the reassembly and maintenance of chromatin structures. Here, we applied drug-free gene silencing assays to analyze the genetic interactions between...
Source: Current Genetics - June 22, 2023 Category: Genetics & Stem Cells Authors: Kholoud Shaban Andrew Dolson Ashley Fisher Emma Lessard Safia Mahabub Sauty Krassimir Yankulov Source Type: research
TOF1 and RRM3 reveal a link between gene silencing and the pausing of replication forks
Curr Genet. 2023 Jun 22. doi: 10.1007/s00294-023-01273-3. Online ahead of print.ABSTRACTEukaryotic DNA replication is accompanied by the disassembly and reassembly of nucleosomes and the transmission of epigenetic marks to the newly assembled chromatids. Several histone chaperones, including CAF-1 and Asf1p, are central to these processes. On the other hand, replication forks pause at numerous positions throughout the genome, but it is not known if and how this pausing affects the reassembly and maintenance of chromatin structures. Here, we applied drug-free gene silencing assays to analyze the genetic interactions between...
Source: Current Genetics - June 22, 2023 Category: Genetics & Stem Cells Authors: Kholoud Shaban Andrew Dolson Ashley Fisher Emma Lessard Safia Mahabub Sauty Krassimir Yankulov Source Type: research
TOF1 and RRM3 reveal a link between gene silencing and the pausing of replication forks
Curr Genet. 2023 Jun 22. doi: 10.1007/s00294-023-01273-3. Online ahead of print.ABSTRACTEukaryotic DNA replication is accompanied by the disassembly and reassembly of nucleosomes and the transmission of epigenetic marks to the newly assembled chromatids. Several histone chaperones, including CAF-1 and Asf1p, are central to these processes. On the other hand, replication forks pause at numerous positions throughout the genome, but it is not known if and how this pausing affects the reassembly and maintenance of chromatin structures. Here, we applied drug-free gene silencing assays to analyze the genetic interactions between...
Source: Current Genetics - June 22, 2023 Category: Genetics & Stem Cells Authors: Kholoud Shaban Andrew Dolson Ashley Fisher Emma Lessard Safia Mahabub Sauty Krassimir Yankulov Source Type: research
TOF1 and RRM3 reveal a link between gene silencing and the pausing of replication forks
Curr Genet. 2023 Jun 22. doi: 10.1007/s00294-023-01273-3. Online ahead of print.ABSTRACTEukaryotic DNA replication is accompanied by the disassembly and reassembly of nucleosomes and the transmission of epigenetic marks to the newly assembled chromatids. Several histone chaperones, including CAF-1 and Asf1p, are central to these processes. On the other hand, replication forks pause at numerous positions throughout the genome, but it is not known if and how this pausing affects the reassembly and maintenance of chromatin structures. Here, we applied drug-free gene silencing assays to analyze the genetic interactions between...
Source: Current Genetics - June 22, 2023 Category: Genetics & Stem Cells Authors: Kholoud Shaban Andrew Dolson Ashley Fisher Emma Lessard Safia Mahabub Sauty Krassimir Yankulov Source Type: research
TOF1 and RRM3 reveal a link between gene silencing and the pausing of replication forks
Curr Genet. 2023 Jun 22. doi: 10.1007/s00294-023-01273-3. Online ahead of print.ABSTRACTEukaryotic DNA replication is accompanied by the disassembly and reassembly of nucleosomes and the transmission of epigenetic marks to the newly assembled chromatids. Several histone chaperones, including CAF-1 and Asf1p, are central to these processes. On the other hand, replication forks pause at numerous positions throughout the genome, but it is not known if and how this pausing affects the reassembly and maintenance of chromatin structures. Here, we applied drug-free gene silencing assays to analyze the genetic interactions between...
Source: Current Genetics - June 22, 2023 Category: Genetics & Stem Cells Authors: Kholoud Shaban Andrew Dolson Ashley Fisher Emma Lessard Safia Mahabub Sauty Krassimir Yankulov Source Type: research
TOF1 and RRM3 reveal a link between gene silencing and the pausing of replication forks
Curr Genet. 2023 Jun 22. doi: 10.1007/s00294-023-01273-3. Online ahead of print.ABSTRACTEukaryotic DNA replication is accompanied by the disassembly and reassembly of nucleosomes and the transmission of epigenetic marks to the newly assembled chromatids. Several histone chaperones, including CAF-1 and Asf1p, are central to these processes. On the other hand, replication forks pause at numerous positions throughout the genome, but it is not known if and how this pausing affects the reassembly and maintenance of chromatin structures. Here, we applied drug-free gene silencing assays to analyze the genetic interactions between...
Source: Current Genetics - June 22, 2023 Category: Genetics & Stem Cells Authors: Kholoud Shaban Andrew Dolson Ashley Fisher Emma Lessard Safia Mahabub Sauty Krassimir Yankulov Source Type: research
TOF1 and RRM3 reveal a link between gene silencing and the pausing of replication forks
Curr Genet. 2023 Jun 22. doi: 10.1007/s00294-023-01273-3. Online ahead of print.ABSTRACTEukaryotic DNA replication is accompanied by the disassembly and reassembly of nucleosomes and the transmission of epigenetic marks to the newly assembled chromatids. Several histone chaperones, including CAF-1 and Asf1p, are central to these processes. On the other hand, replication forks pause at numerous positions throughout the genome, but it is not known if and how this pausing affects the reassembly and maintenance of chromatin structures. Here, we applied drug-free gene silencing assays to analyze the genetic interactions between...
Source: Current Genetics - June 22, 2023 Category: Genetics & Stem Cells Authors: Kholoud Shaban Andrew Dolson Ashley Fisher Emma Lessard Safia Mahabub Sauty Krassimir Yankulov Source Type: research
TOF1 and RRM3 reveal a link between gene silencing and the pausing of replication forks
Curr Genet. 2023 Jun 22. doi: 10.1007/s00294-023-01273-3. Online ahead of print.ABSTRACTEukaryotic DNA replication is accompanied by the disassembly and reassembly of nucleosomes and the transmission of epigenetic marks to the newly assembled chromatids. Several histone chaperones, including CAF-1 and Asf1p, are central to these processes. On the other hand, replication forks pause at numerous positions throughout the genome, but it is not known if and how this pausing affects the reassembly and maintenance of chromatin structures. Here, we applied drug-free gene silencing assays to analyze the genetic interactions between...
Source: Current Genetics - June 22, 2023 Category: Genetics & Stem Cells Authors: Kholoud Shaban Andrew Dolson Ashley Fisher Emma Lessard Safia Mahabub Sauty Krassimir Yankulov Source Type: research
TOF1 and RRM3 reveal a link between gene silencing and the pausing of replication forks
Curr Genet. 2023 Jun 22. doi: 10.1007/s00294-023-01273-3. Online ahead of print.ABSTRACTEukaryotic DNA replication is accompanied by the disassembly and reassembly of nucleosomes and the transmission of epigenetic marks to the newly assembled chromatids. Several histone chaperones, including CAF-1 and Asf1p, are central to these processes. On the other hand, replication forks pause at numerous positions throughout the genome, but it is not known if and how this pausing affects the reassembly and maintenance of chromatin structures. Here, we applied drug-free gene silencing assays to analyze the genetic interactions between...
Source: Current Genetics - June 22, 2023 Category: Genetics & Stem Cells Authors: Kholoud Shaban Andrew Dolson Ashley Fisher Emma Lessard Safia Mahabub Sauty Krassimir Yankulov Source Type: research
TOF1 and RRM3 reveal a link between gene silencing and the pausing of replication forks
Curr Genet. 2023 Jun 22. doi: 10.1007/s00294-023-01273-3. Online ahead of print.ABSTRACTEukaryotic DNA replication is accompanied by the disassembly and reassembly of nucleosomes and the transmission of epigenetic marks to the newly assembled chromatids. Several histone chaperones, including CAF-1 and Asf1p, are central to these processes. On the other hand, replication forks pause at numerous positions throughout the genome, but it is not known if and how this pausing affects the reassembly and maintenance of chromatin structures. Here, we applied drug-free gene silencing assays to analyze the genetic interactions between...
Source: Current Genetics - June 22, 2023 Category: Genetics & Stem Cells Authors: Kholoud Shaban Andrew Dolson Ashley Fisher Emma Lessard Safia Mahabub Sauty Krassimir Yankulov Source Type: research
TOF1 and RRM3 reveal a link between gene silencing and the pausing of replication forks
Curr Genet. 2023 Jun 22. doi: 10.1007/s00294-023-01273-3. Online ahead of print.ABSTRACTEukaryotic DNA replication is accompanied by the disassembly and reassembly of nucleosomes and the transmission of epigenetic marks to the newly assembled chromatids. Several histone chaperones, including CAF-1 and Asf1p, are central to these processes. On the other hand, replication forks pause at numerous positions throughout the genome, but it is not known if and how this pausing affects the reassembly and maintenance of chromatin structures. Here, we applied drug-free gene silencing assays to analyze the genetic interactions between...
Source: Current Genetics - June 22, 2023 Category: Genetics & Stem Cells Authors: Kholoud Shaban Andrew Dolson Ashley Fisher Emma Lessard Safia Mahabub Sauty Krassimir Yankulov Source Type: research
Yeast of Eden: microbial resistance to glyphosate from a yeast perspective
Curr Genet. 2023 Jun 3. doi: 10.1007/s00294-023-01272-4. Online ahead of print.ABSTRACTFirst marketed as RoundUp, glyphosate is history's most popular herbicide because of its low acute toxicity to metazoans and broad-spectrum effectiveness across plant species. The development of glyphosate-resistant crops has led to increased glyphosate use and consequences from the use of glyphosate-based herbicides (GBH). Glyphosate has entered the food supply, spurred glyphosate-resistant weeds, and exposed non-target organisms to glyphosate. Glyphosate targets EPSPS/AroA/Aro1 (orthologs across plants, bacteria, and fungi), the rate-l...
Source: Current Genetics - June 3, 2023 Category: Genetics & Stem Cells Authors: Dionysios Patriarcheas Taizina Momtareen Jennifer E G Gallagher Source Type: research
Yeast of Eden: microbial resistance to glyphosate from a yeast perspective
Curr Genet. 2023 Jun 3. doi: 10.1007/s00294-023-01272-4. Online ahead of print.ABSTRACTFirst marketed as RoundUp, glyphosate is history's most popular herbicide because of its low acute toxicity to metazoans and broad-spectrum effectiveness across plant species. The development of glyphosate-resistant crops has led to increased glyphosate use and consequences from the use of glyphosate-based herbicides (GBH). Glyphosate has entered the food supply, spurred glyphosate-resistant weeds, and exposed non-target organisms to glyphosate. Glyphosate targets EPSPS/AroA/Aro1 (orthologs across plants, bacteria, and fungi), the rate-l...
Source: Current Genetics - June 3, 2023 Category: Genetics & Stem Cells Authors: Dionysios Patriarcheas Taizina Momtareen Jennifer E G Gallagher Source Type: research
